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Feminism: Sex and gender discussions

Puberty blockers Lupron.

33 replies

panjandrumpyjamas · 20/04/2018 23:18

I knew that there was a problem with Lupron with regards to osteoporosis www.statnews.com/2017/02/02/lupron-puberty-children-health-problems/

but I didnt realize that it was used as a chemical for castration!
clinicaltrials.gov/ct2/show/NCT00220350

Does anyone have access to information as to why this drug is deemed safe for children? www.consumeraffairs.com/news/new-report-describes-dangers-of-giving-lupron-to-kids-020317.html

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DisturblinglyOrangeScrambleEgg · 21/04/2018 06:26

The only way they justify this is by saying that it's safer than your child killing themselves. That's the only way you can justify any dangerous drug - are the side effects of the drug better than the thing you're using it to do.

Eg. The Pill - has side-effects, but safer than pregnancy. Vaccination - has possible side effects, but safer than the diseases themselves. Then you balance this risk/reward for the patient.

So someone with severe dysphoria, who's not got better with therapy, might go for surgery. Someone in continuous pain, will take strong painkillers that will probably eventually lead to their death.

And these puberty blockers are so dangerous, that the only way these people can justify giving them to kids is to say that the alternative is that the children will suicide - they're so dangerous, they have to go straight to death as the alternative to balance against.

And what's crazy about this, is there isn't even proof of this high rate of suicide specific to trans. Read any study, and there's a high rate of co-morbidity with other mental health issues, or with other reasons for increased risk of suicide (eg being gay or lesbian in an unwelcoming environment) - but rather than research this, or try to reduce the suicide risk in other ways (eg, the LGB - 'it gets better' campaign) it's used as a justification for damaging these kids with dangerous drugs.

miri1985 · 21/04/2018 06:04

I came to gender critical feminism because of lupron. I have endometriosis was reading an endo board discussion about the side effects (note adult women are put on it for no longer than 6 months) and I was just shocked at what is being done to these children when I found out that this is the puberty supressing drug and did my research.

Every time I read people talking about puberty blockers being completely safe and allowing children to pause, make decisions etc, I cringe because the physical ramifications of these drugs are well known by now and they are anything but safe.

Others have already provided the links for the physical problems that lupron can cause but it also has effects on the developing brain that we don't fully understand yet.
They've done at least 2 studies on girls (not transgender) who were given puberty blockers for a short period as they were going through early puberty. On average their IQ went down 8 points (7 points in the other study) in the year or so they took the blockers, in the most recent study 2 out of 15 who were given the drugs ended up being held back a year at school.

7-8 IQ points aren't that much if your IQ is starting out fairly high but losing that amount (or more) makes a lot of difference if your starting IQ is low and as far as I can see there aren't studies on how this effects children who are suppressed for their whole puberty and beyond.

www.frontiersin.org/articles/10.3389/fpsyg.2017.00044/full#B8

www.ncbi.nlm.nih.gov/pubmed/11683207

TerfinUSA · 21/04/2018 05:10

The liars at a certain charity will tell you it's not used in the UK, this is not true, it is. Further, there are other drugs that are more commonly used instead in the UK that work in exactly the same way, as they are from the same class of hormone drug (GnRH agonists). I think the specific coverage of Lupron just reflects the much bigger and more open US drug market, so the publicity reflects what's used over there.

Xenophile · 21/04/2018 00:24

You can't test for drug safety with children. It would be an ethical minefield. Can you imagine?

"Oh, yes Mr and Ms Bloggs, we're doing a double blind trial of this potentially life saving drug, so, some kids will be getting the real thing and others will be getting something else, you good with that? Even if little Johnny gets the real deal, we don't know if it will have deleterious side effects, we good to go?"

What tends to happen is that drugs are tested on adults, often males, often white, and then dosages are tweaked for children's bodies. It's an educated gues, but still a guess.

Xenophile · 21/04/2018 00:16

It's not safe for children.

It's not reversible in the majority of cases.

It has a relatively high death rate.

LineyHasntLeftTheBuilding · 20/04/2018 23:54

I don't think it is deemed safe for children, from what I can see. Happy to be corrected, though.

I wonder who has an interest in promoting its use in children? And why?

I know there were potential issues raised by some parties way back re fluoxentine / prozac in under-18s from memory. Does anyone recall that? About lack of testing.

thebewilderness · 20/04/2018 23:49

It is not deemed safe for children.
It is being used off label.
www.lupronvictimshub.com/lawsuits.html

panjandrumpyjamas · 20/04/2018 23:24

The other side of lupron

transhealth.phsa.ca/medical-options/hormones/puberty-blockers

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