BertrandRussell "Hugh-do you have any data less than 17 years old?"
The Hhorages France study I linked to previously:
www.intechopen.com/books/state-of-the-art-of-therapeutic-endocrinology/behavioral-and-somatic-disorders-in-children-exposed-in-utero-to-synthetic-hormones-a-testimony-case
was published in 2012.
This study:
www.ncbi.nlm.nih.gov/pmc/articles/PMC3146061/
was published in 2009. It's particularly significant as far as the dependence of human "brain sex" on prenatal androgen levels, because Rhesus monkeys are one of the closest animal models to human beings, and the research shows that exposure to external hormones can alter the sex of their brain.
"Studies over the last 50 years have verified that prenatal androgens have permanent effects in rhesus monkeys on the neural circuits that underlie sexually dimorphic behaviors. These behaviors include both sexual and social behaviors, all of which are also influenced by social experience. Many juvenile behaviors such as play and mounting are masculinized, and aspects of adult sexual behavior are both masculinized (e.g. approaches, sex contacts, and mounts) and defeminized (e.g. sexual solicits). "
The fact that they could produce female monkeys with male brains just by prenatally exposing them to testosterone, makes it highly plausible that drugs with testosterone suppressing properties (such as DES or progestins) can produce the reverse effect, of driving female brain development in male foetuses. As the experiences of people such as Ailynn and I show, DES definitely has caused female brain development in male assigned human beings, however it's very likely that progestins do the same thing (because they also are powerful testosterone suppressants). The fact that progestins remain in widespread use during pregnancy, perhaps along with third generation effects, would explain why gender clinic referrals continue to soar.
Most of the papers reporting on the high failure rates of infant gender reassignments are clustered around 2000 - 2005, but most likely that's because there was an expose in 1997 showing the David Reimer case to be a failure, and follow up studies of other infant reassignments were most likely organised in response, to see whether there was a problem with them too. There was.
www.ncbi.nlm.nih.gov/pmc/articles/PMC1421518/
"Conclusion: Active prenatal androgen effects appeared to dramatically increase the likelihood of recognition of male sexual identity independent of sex-of-rearing. Genetic males with male typical prenatal androgen effects should be reared male."
There most likely haven't been many further studies along those lines since about 2005 because by then the point had already been made: Dr Money (and Dr Zucker) were wrong: your gender identity is hardwired into your brain and already in place by the time you're born, and you can't arbitrarily reassign babies to another sex and expect it to work.