Boys wise, in South Bucks, you have lots of choice and your commuting distance will be reasonable.
Aylesbury Grammar and Dr Challoners are both great schools as is Waddesdon but much further out for commuting into London. Even Marlow is a bit of a push if driving and you have to be in catchment for Borlase or you'll have difficulties come 6th form time unless your boys are very academic.
Wycombe schools are a good option because you have the RGS as the high academic school and JHGS is the more nurturing, art and design focus school. Both have the same 11+ pass rate but have different skills IYSWIM. Nice to have a choice. Commuting is easy to London, even from the outer villages.
Having said that, Marlow is next to Maidenhead and Crossrail is going to make it much faster (and unfortunately more expensive and it's already bloody pricey!) so commuting from there would be ok too.
In terms of secondary schools, Great Marlow and Highcrest in Wycombe are considered to be good schools. Beaconsfield is also good. Princes Risborough is a good school but then you'd be looking at a much longer commute (though my Dad does it from around there and he manages ok!).
Really what I'm saying is that is depends on your house budget and how long your other half is willing to commute for. If he wants to drive in to London, you'll need to make different choices to the train etc.
The areas with good schools are priced accordingly, unfortunately.