If Covid has become less of a worry, and the 2024 elections are in any way contentious, then yeah, the potential is there. For instance, Democrat senators represent 40 million more people than the Republicans, but the senate is split 50:50. Also Biden got 10 million more votes than Trump, but if he was short of around 50,000 in the right places he'd have lost - numbers like those would seem to me to be a cause of some tension....
The republicans are changing the voting borders around in as many places as they can to ensure they get control of the lower house, even if they get fewer votes (and in the meantime making it harder and harder to vote in democrat strongholds), and some state legislatures are threatening to send their electoral college votes in for the Republican candidate, even if the Democrat wins in their state (which they're allowed to do BTW).