Please or to access all these features

Conception

When's the best time to get pregnant? Use our interactive ovulation calculator to work out when you're most fertile and most likely to conceive.

Immune/NK cells pred thread #34

929 replies

Hopeandfaith1990 · 03/08/2025 14:52

Hi all, started a new thread as the old one was full. Not sure if this is the way to do it but I've c&p'd the list of people on the previous one as much as poss:

Old thread here: https://www.mumsnet.com/talk/conception/5228367-immunenk-cells-pred-thread-33?page=40

@Jecca88
@Gizmo1983
@Deerdancer34
@Objectiontime
@SWMum9
@TammyinCork
@Newbeginnings22023
@Fletchasketch
@Morgan236
@CarpeDiem75
@ALittleLight
@MC8
@venusStarr
@Gizmo1983
@Carportforme
@Meg310532
@Newbeginnings22023
@recurrentmis
@hopefulH
@v60
@lozzmax
@fleur89
@motherofshihtzus
@sunflower360
@kea1990
@sprinkleofbabydust
@star2022
@rumandspinach
@ems123456789
@rainbowsunshine81
@mamaw05
@thornters
@elarcoiris

Page 40 | Immune/NK cells pred thread #33 | Mumsnet

Hey Guys, starting a new thread as we have run out of space - hope i have included everyone and sending lots of love x {mention:venusStarr} {mention:...

https://www.mumsnet.com/talk/conception/5228367-immunenk-cells-pred-thread-33?page=40

OP posts:
Thread gallery
8
LoudAquaMoose · 21/12/2025 08:10

Hey guys - I have been following this chat for a while. I am under Dr Shehata’s complex plan and am about 4.5 weeks pregnant on the first month of trying on the plan which I am very shocked by. I had 2 miscarriages this year - the second we tested and it was euploid so knew there was something pathological with me. I have PCOS, hashimotos, reactive arthritis in the past and high NK activation and tilt. Someone here mentioned a thin lining which is the same as me - I opted for PRP on this cycle and it worked well initially!

Totally empathise with everyone’s health anxiety. Truly awful after loss. I am worried I have ectopic (some left sided ache) so going to EPU on Monday to see if they can confirm for me.

Either way so many you have had such a terrible time and I’m thinking of us all as we navigate this great misfortunes!

pagey23 · 19/12/2025 16:58

@Hopeandfaith1990Oh that’s interesting… maybe there’s been a new paper that’s come out and they’ve changed their view on it? I hadn’t seen it myself and I’m surprised their wording is so against it…

i went to see dr edge today for my first super ovulation appointment. One follicle looks good size wise but another is lagging behind a bit so I’m triggering myself tomorrow evening. She said my lining is satisfactory but on the thin side so I’m also taking estrogen now. Literally swamped with meds but feeling positive!! Maybe the thin lining (as well as stress) is stopping me from falling pregnant… so I’m working on both of those things now. Still off work but have been angry at them as they are paying me statutory sick pay (SSP) after five days of consecutive sick leave (£118/week). How can anyone live on that?! Doesn’t help when you get a £1.1k CRP bill either 😫😫 anyway, trying not to worry about money and enjoy my time off.

Lot of love to everyone xx

Hopeandfaith1990 · 19/12/2025 12:55

This is what I meant to include above:

Immune/NK cells pred thread #34
OP posts:
SWMum9 · 19/12/2025 12:54

Hopeandfaith1990 · 19/12/2025 12:52

Hi @SWMum9 so happy to hear from you and hear your lovely news! Congrats. When is your first scan? I absolutely did not stay calm haha. I was crying before the doctor had even put the ultrasound in hahaha. She said 'you can smile now, there is a heartbeat' and then I continued crying but happy tears then! I was the same for my second scan, crying and could barely breathe again and this one was worse because the doctor went from over the tummy to internal which obviously panicked me. I think its impossible to stay calm with our history! Be kind to yourself and let yourself feel the things you feel. I'm journally/affirming/colouring in A LOT especially as my husband has been away this week skiing.

I'm still paranoid that I should have taken the hydroxy. Did you tell RMC you stopped and started it?

Hope everyone is well. @Jecca88 how many weeks are you now and have you had any more scans?

I was doing some research last night and came across the Tommy's NK cells page - does anyone else think its strange that they're basically completely going against the NK cells now? I swear they used to support the treatment.

Edited

No I haven’t mentioned that I stopped and started.

I left a voicemail with EPU today to book my scan. I think for w/c 29th Dec.

keeping everything crossed!

Hopeandfaith1990 · 19/12/2025 12:52

Hi @SWMum9 so happy to hear from you and hear your lovely news! Congrats. When is your first scan? I absolutely did not stay calm haha. I was crying before the doctor had even put the ultrasound in hahaha. She said 'you can smile now, there is a heartbeat' and then I continued crying but happy tears then! I was the same for my second scan, crying and could barely breathe again and this one was worse because the doctor went from over the tummy to internal which obviously panicked me. I think its impossible to stay calm with our history! Be kind to yourself and let yourself feel the things you feel. I'm journally/affirming/colouring in A LOT especially as my husband has been away this week skiing.

I'm still paranoid that I should have taken the hydroxy. Did you tell RMC you stopped and started it?

Hope everyone is well. @Jecca88 how many weeks are you now and have you had any more scans?

I was doing some research last night and came across the Tommy's NK cells page - does anyone else think its strange that they're basically completely going against the NK cells now? I swear they used to support the treatment.

OP posts:
pagey23 · 18/12/2025 15:23

Congratulations!!! What lovely news before Christmas!

SWMum9 · 18/12/2025 12:06

Deerdancer34 · 18/12/2025 10:54

@SWMum9 Many congratulations 🥰 The lines sound really good! I remember seeing the lines when I conceived my daughter and thinking, oh that's what they are supposed to look like 😅

Thank you all for being such a supportive group, it's a lifeline this isn't it 😘 Hope everyone doing ok 💓

That’s exactly how I felt. None of this squinting under certain lights and pretending I can see things like I’ve been doing for god knows how long 😆

Deerdancer34 · 18/12/2025 10:54

@SWMum9 Many congratulations 🥰 The lines sound really good! I remember seeing the lines when I conceived my daughter and thinking, oh that's what they are supposed to look like 😅

Thank you all for being such a supportive group, it's a lifeline this isn't it 😘 Hope everyone doing ok 💓

Gems2811 · 18/12/2025 07:36

Gentle congratulations @SWMum9 the really strong lines sound promising! Xx

Rainbowchaser87 · 17/12/2025 22:56

@SWMum9 congratulations darling!!! I pray this baby will thrive!!🙏🏽❤️ thanks for sharing…

SWMum9 · 17/12/2025 14:47

Hi ladies, sorry I’ve been MIA here. After our chemical last month I fell into a bit of a hole thinking this will never happen. I came off all pregnancy related apps and just gave my brain a rest.

I have happy news again that I am pregnant this month. 5 weeks today and two realllly strong dark lines at 12 and 17dpo. With my previous losses I didn’t ever get lines this dark so it feels like a positive sign. Cramping, sore boobs, all the right signs but I feel super super anxious and don’t want to tell anyone yet. Counting down until I can have the 7 week scan under the RM team.

@Jecca88 so pleased to hear about your scans, amazing. I hope you are able to relax into things a little now.

@Hopeandfaith1990 I hope you’re keeping well. I just saw your comment about seeing the heart beat at 6weeks 4 days 🥹🥹. How did you stay calm? I already feel sick thinking about that first scan, if I get there.

@ChaE05 I understand your concerns about the hydroxy. I didn’t have the normal side affects they detail but I do think the combo of that and pred messed up my cycle a little. I stopped taking it for two months but have started up again when I got a positive test.

@Deerdancer34 so sorry to hear your sad news. Thinking of you

Sending love to everyone and hello to the new comers. This is a really supportive place. Merry christmas xx

Gems2811 · 17/12/2025 12:51

@Deerdancer34 I'm terribly sorry, what a double shock for you both, sending you all the love and you're right, one day at a time. Hoping for a lovely BFP for you xxx

Rainbowchaser87 · 16/12/2025 13:38

@Deerdancer34 gosh!! I am soo sorry that all this is happening to you! I really hope that this year won’t end with just sad news for u both but with a wonderful bfp and a baby that will thrive into your uterus! I pray your brother will fight and overcome this battle as well!! 🙏🏽
sending u love darling…you will get through this!!❤️ 🫂

Deerdancer34 · 16/12/2025 09:31

@Hopeandfaith1990@Jecca88 @pagey23 @Rainbowchaser87 Thank you ladies for your lovely words. We're just reeling from the shock and I know it will be a process to comes to terms with. It's never the right time to lose anybody but it feels too early. At least my husband is talking about it. To add insult to injury, my brother rang last night to say he'd been diagnosed with lymphoma, so waiting on prognosis of that. Anyway one day at a time is my motto with anything I find hard 😅
We had actually already triggered, so I'm continuing with the meds this cycle but I doubt implantation will work...would be a lovely miracle! Sorry for the dampener, give everyone you love an extra squeeze 💓

Hopeandfaith1990 · 15/12/2025 20:19

@Deerdancer34 sending you all my love, I’m so sorry :-( life can be so cruel. Thinking of you xxx

OP posts:
Rainbowchaser87 · 15/12/2025 20:16

@Gems2811 I am soo really sorry…my love and prayers are for you now….

@Deerdancer34so sorry for u too…sending you love and prayers too…

Jecca88 · 15/12/2025 11:01

Oh my god @Deerdancer34 i am so sorry for your loss. Sending you so much strength in this horrible time. You poor thing, it just doesn't feel fair to have that much grief and around this time of year too. How are you?

pagey23 · 15/12/2025 10:05

@Gems2811gosh this is so awful. I’m so sorry to hear. Is there anything that you can take to lower the risk of it happening again or is it more luck of the draw kind of thing? Take care and look after yourself during this time. It’s really good to know the cause - I’ve had two miscarriages and didn’t even know it was possible to find out!

@Deerdancer34what a shock - you must all be going through so much😢 I’ve had this happen a few times and it’s hard to get your head around it. So sorry to hear this and take care. it might be worth skipping this cycle if it’s too overwhelming and they do say you need a break from the meds every 6 months so it might be a good time if you are coming up to that time? Big hugs

Deerdancer34 · 15/12/2025 09:51

@Gems2811 I am so sorry, its really not easy. It helps a bit to know the reason for your loss but it doesn't make it any better. Hopefully they will offer you testing and that will give you a bit more reassurance to carry on 😘

We lost my Father in Law very suddenly, so I'll be surprised if this cycle works 😔 Depends how much grief affects biology I suppose.

Lots of love everyone ❤️

Jecca88 · 15/12/2025 06:20

Oh @gems2811 I’m so sorry to read this, I can totally relate and it really took me back when we found out our boy from Jan this year had trisomy 21. He died at just 12 weeks, but I was in a way relieved that I didn’t have to make any decision and it was taken out of our hands despite the absolute heartbreak.

It too shook me up going forward - however the hospital should offer you parental karyotype test to check if either you or your partner carry a translocation for trisomy 13- to see your chances of it happening again. Sending love! Xxx

Hopeandfaith1990 · 13/12/2025 06:58

Thank you all! Really trying to work on the old positive mindset because my mind has been to some very dark places this week 😅

@Gems2811 I’m so sorry, it must have been incredibly difficult to receive that news and I can understand how it would impact your confidence going forward. I agree that there’s reassurance in knowing it wasn’t immune, and perhaps also that there was literally nothing more you could have done to protect him, as crushingly heartbreaking as that is, you did everything you could. Sending love xxx

OP posts:
Gems2811 · 12/12/2025 18:28

@Hopeandfaith1990 so happy for you! I was so hoping to read this 🩷 so wonderful

Got everything crossed for the 23rd for you @Deerdancer34

Thank you for this @pagey23 and that does sound like a good idea

Thank you for your insight on the testing @Hopeandfaith1990 and @Jecca88 , I got a phone call today when I followed up and baby had Patau syndrome trisomy 13 and he was a little boy. I feel very sad but there’s some reassurance for me that it wasn’t immune related. It has shaken my confidence to try again though 😔

Deerdancer34 · 12/12/2025 15:33

@Jecca88 I realised I counted the days wrong, pregnancy test 23rd, so have booked in for 23rd in case it is positive 🙏 Would be lovely...

@Hopeandfaith1990 Completely over the moon for you 🥰🥰🥰🥰 It's really wonderful news!

Much love to all 💞

Jecca88 · 12/12/2025 13:10

ahhhh the news i was coming on here to read @Hopeandfaith1990 yay! Keep taking it day by day my love - you have got this :)

Hopeandfaith1990 · 12/12/2025 11:54

All good guys, baby still has a heartbeat and is measuring 7w3d so exactly right for one week on. Almost doubled in size 🥰 relieved and really going to try and work on my anxiety management now I’m on my last day of school for the Christmas holidays too. Love to all xxx

OP posts:
Swipe left for the next trending thread