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Conception

When's the best time to get pregnant? Use our interactive ovulation calculator to work out when you're most fertile and most likely to conceive.

TTC Active Letrozole Thread

497 replies

Angelselevenx · 28/02/2024 17:09

Struggling to find an active Letrozole thread. Recently been prescribed Letrozole as I have low progesterone and signs of ovulation not being as effective as it could be, albeit I still ovulate on my own.

Would love to hear success stories or chat to people who are going through TTC with letrozole now x

OP posts:
Thread gallery
17
worldwidetravel2017 · 13/09/2024 11:10

Angelselevenx · 13/09/2024 11:05

@worldwidetravel2017 I'm already on round 7, so will be 11 by then

Have you had your feretin tested ?

Low feretin can make implantation impossible

My consultant discussed feretin with me yest

Angelselevenx · 13/09/2024 11:05

@worldwidetravel2017 I'm already on round 7, so will be 11 by then

OP posts:
worldwidetravel2017 · 13/09/2024 10:56

Angelselevenx · 13/09/2024 06:46

@Plumchumm yeah they've given me enough letrozole to last until January when we have our ivf funding appointment. It's been okay, it obviously hasn't worked for us yet but it's increased my progesterone like it needed to and now with the added progesterone I just need to hope it works but tbh I'm not feeling hopeful 🫣. Really hope it works for you though! There's lots of mixed reviews on it for people who ovulate already x

Is that 6 Letrozole cycles done by jan ?

susie1984234 · 13/09/2024 08:36

@BreakfastOats im taking 5000 I.E Vitamin D every day and have been for about 6 months now. Haven't had my AMH checked lately so not sure if it's improving but it can't do any harm :)
Taking also folic acid, coq10, vitamin E and melatonin as well. I read It Starts With the Egg and this was recommended for miscarriage prevention.

worldwidetravel2017 · 13/09/2024 08:32

Angelselevenx · 13/09/2024 06:46

@Plumchumm yeah they've given me enough letrozole to last until January when we have our ivf funding appointment. It's been okay, it obviously hasn't worked for us yet but it's increased my progesterone like it needed to and now with the added progesterone I just need to hope it works but tbh I'm not feeling hopeful 🫣. Really hope it works for you though! There's lots of mixed reviews on it for people who ovulate already x

Your doing better than me! It didn't increase my progsterone
Sending all the luck

BreakfastOats · 13/09/2024 07:51

@Angelselevenx Thank you, this is almost 3 times what I take! I’m off to Boots to buy some extra vitamin d today!!! 😅
Good news about your progesterone btw! Being hopeful is really hard while on this journey. I’ve been trying to convince myself to focus on the positives everyday 😅

@LucyLou0527 Happy for you👏

Angelselevenx · 13/09/2024 06:46

@Plumchumm yeah they've given me enough letrozole to last until January when we have our ivf funding appointment. It's been okay, it obviously hasn't worked for us yet but it's increased my progesterone like it needed to and now with the added progesterone I just need to hope it works but tbh I'm not feeling hopeful 🫣. Really hope it works for you though! There's lots of mixed reviews on it for people who ovulate already x

OP posts:
Angelselevenx · 13/09/2024 06:11

@BreakfastOats sorry to jump in, I take 4000iu viramin d3

OP posts:
LucyLou0527 · 12/09/2024 23:32

BreakfastOats · 12/09/2024 22:29

@worldwidetravel2017thanks for the vitamin d tip! BTW I also had a hycosy done privately as I didn’t want to wait a year on the NHS! @susie1984234 I take perceive max which contains 35ug D3. Can I ask what dose do you take? :)

@LucyLou0527 The line looks quite dark to me! Have you heard of the Premom app? You can upload pictures of your tests and the app will recognise your peak.

Hey, I know I’m over the moon!

Premom says it was 0.82 wet and 0.99 dry so I’m really happy with either🩷

TTC Active Letrozole Thread
Plumchumm · 12/09/2024 23:04

Angelselevenx · 12/09/2024 19:37

@Plumchumm I ovulate cd 20-23 without letrozole and CD16 each time on the last 6 cycles (bar last cycle was CD19 as I was put on metformin but I've stopped that now). Best of luck x

Thank you, I hope it’s like that for me. How’s your cycles on Letrozole been? Are you doing another? My partner and I actually went to go and do IVF but our fertility nurse said let’s try this first x

BreakfastOats · 12/09/2024 22:29

susie1984234 · 12/09/2024 15:57

@worldwidetravel2017 yes I've been taking high dose vitamin D. My AMH went from an undetectable 0.13 to 0.50. Still terribly low but some improvement ( in this time I'll take any small victory 😅)

My specialist also said I should wait until 6 months on Letrozole before getting my tubes checked - it's a long time! If you are able to go private and get it done quicker then it's worth it for your peace of mind

@worldwidetravel2017thanks for the vitamin d tip! BTW I also had a hycosy done privately as I didn’t want to wait a year on the NHS! @susie1984234 I take perceive max which contains 35ug D3. Can I ask what dose do you take? :)

@LucyLou0527 The line looks quite dark to me! Have you heard of the Premom app? You can upload pictures of your tests and the app will recognise your peak.

LucyLou0527 · 12/09/2024 20:49

Update!

CD13 PM test, is this close to peak?

TTC Active Letrozole Thread
TTC Active Letrozole Thread
worldwidetravel2017 · 12/09/2024 19:50

Im expecting them to find evidence of either endo
Or pelvic inflammatory disease with tube flush

I had abnormal ca125 last yr - can be raised in endo or pid

Angelselevenx · 12/09/2024 19:37

@Plumchumm I ovulate cd 20-23 without letrozole and CD16 each time on the last 6 cycles (bar last cycle was CD19 as I was put on metformin but I've stopped that now). Best of luck x

OP posts:
worldwidetravel2017 · 12/09/2024 19:29

Also - was thinking over things earlier

Another thing i got checked on NHS in past

=
Prolactin

worldwidetravel2017 · 12/09/2024 19:27

Letrozole of 2.5 mg
Bought my ovulation forward by a week each time
On letrozole cycles 1 & 2

Plumchumm · 12/09/2024 18:04

Hi ladies, starting Letrozole for the first time soon. We just signed the paperwork today. This will be baby #1 but I’ve been pregnant before, had mc and ectopic.

but I’ve pcos and very long cycles so going to induce a period first.

just a bit worried because my partner and I are away to Sicily for a week on the 23rd. They don’t want to let us take anything till we’re back because we are being monitored and triggered this cycle.

Ive had overstimulation in the past which resulted in an ectopic so I suppose I shouldn’t risk it by taking the pills while abroad or away. Just wish the timing lined up better

starting on 5mg, they said if follicles don’t seem to be growing they will add FSH injections. I have very high AMH levels so basically play it by ear. I don’t regularly ovulate but when I have in the past it’s been around CD 20-22.

i hope Letrozole brings ovulation forward. I’ve never had CD14 ovulation in my life

worldwidetravel2017 · 12/09/2024 16:11

Have u all made sure your t s h
Is 2.5 or less

worldwidetravel2017 · 12/09/2024 16:10

susie1984234 · 12/09/2024 15:57

@worldwidetravel2017 yes I've been taking high dose vitamin D. My AMH went from an undetectable 0.13 to 0.50. Still terribly low but some improvement ( in this time I'll take any small victory 😅)

My specialist also said I should wait until 6 months on Letrozole before getting my tubes checked - it's a long time! If you are able to go private and get it done quicker then it's worth it for your peace of mind

Sometimes nhs say after 3 letrozole cycles
Letrozole = you only get given so many cycles

Def better 4 me and any1 / every1 to get it done asap

I i should have it done in the first half of Oct

susie1984234 · 12/09/2024 15:57

@worldwidetravel2017 yes I've been taking high dose vitamin D. My AMH went from an undetectable 0.13 to 0.50. Still terribly low but some improvement ( in this time I'll take any small victory 😅)

My specialist also said I should wait until 6 months on Letrozole before getting my tubes checked - it's a long time! If you are able to go private and get it done quicker then it's worth it for your peace of mind

worldwidetravel2017 · 12/09/2024 15:04

Those of u with amh - my friend has low amh - we read that daily vit d can help

Angelselevenx · 12/09/2024 15:00

@worldwidetravel2017 I went private with mine as also had a 6 month wait. Got it done within 2 weeks.

@BreakfastOats I track my BBT so know when I ovulate, did it at 7dpo and was 19nmol. They want over 30. Since progesterone I've had borderline over 30 so progesterone should give it that extra boost x

OP posts:
BreakfastOats · 12/09/2024 14:58

susie1984234 · 12/09/2024 12:22

@BreakfastOats that's a nice big follicle!
I also don't habe PCOS and have low AMH.

I got pregnant on my first round of Letrozole (although ended in a loss)

I'm the same as you, had scan on Monday (CD11) I had a 15mm follicle and 9mm lining, dr wanted me to wait until last night to trigger, hopefully my follicle grew nicely in that time.

Best of luck to you!

So sorry you suffered a loss and fingers crossed for this attempt! Doctors say that low AMH shouldn't prevent natural conception so let's hope we'll get lucky soon!

BreakfastOats · 12/09/2024 14:52

Angelselevenx · 12/09/2024 07:56

@BreakfastOats best of luck! I'm the same as you, no PCOS (but I do have PCO), regular ovulation/cycles etc. I do have low progesterone, finally been prescribed progesterone from 2dpo this cycle. On month 7 of letrozole now (7.5mg).

IVF funding appointment is January so just trying to get through these last few months 😂

Thank you and best of luck to you too! How did you find out you have low progesterone? I only tested my levels once since we started ttc and that was on day 21 to confirm ovulation. They were normal at the time.

worldwidetravel2017 · 12/09/2024 13:57

Tube flush will be private due to nhs wait times - i cant wait 5 - 6 months

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