Help protect children from gaming harms.

Take our survey

Please or to access all these features

Conception

When's the best time to get pregnant? Use our interactive ovulation calculator to work out when you're most fertile and most likely to conceive.

What's IVF *really* like?

63 replies

JaneHH · 01/03/2008 17:59

Hi everyone

DH and I are almost 99% sure we're going to start on IVF in the next few months - I can get pregnant but I don't want to pass on something hereditary which I have. So IVF will -hopefully- help us in that department.

So I was wondering whether anyone else has done IVF with PGD (pre-implantation genetic diagnosis)?

But I was mainly wondering what it's REALLY like to have IVF... What can we expect besides all sorts of trips to the chemist and self-mutilation with daily hormone injections? Is it manageable or more realistically truly hideous? What do I need to steel prepare myself/ourselves for?

Thanks for all your help, MN'ers!

---------------------

Hi there - this thread is a little old. [[https://www.mumsnet.com/conception/ivf
If you want to find out about IVF, we’ve got more information here]]. MNHQ

OP posts:
Kewcumber · 01/03/2008 21:16

This particular recruitment guy looked about 12 and like he wanted the ground to open up and swallow him. It swas almost worth putting up with the IVF for that alone!

JaneHH · 01/03/2008 21:05

1wish you are NOT hijacking, we're all in this together (with or without wine I'm on the "with wine" side btw )

Kewcumber your reaction sounds rather like the matching pants and socks things from LG&T's thread last week (think you were on that one too) - scare people with tmi and they'll shut up sharpish

Money is not really an issue, so I feel very lucky - I'm in Holland and we don't have an NHS here but it's all done with medical insurance. Can't remember how exactly many cycles are covered by my insurance but I have savings precisely for this purpose. Obviously wouldn't keep going for the 50th time... but there are other factors which I have to worry about, let's put it that way. I do realise I'm very lucky in this respect.

I think I will have to tell my employer - not expecting too much trouble with that as I will just have to take the time out of my holiday time. Am more worried about the constant nipping in and out of the office to the other end of Holland without explanation... HELP!

OP posts:
jenkel · 01/03/2008 21:02

From what I could remember for almost 2 weeks I was at the clinic every other day and at different times, I guess it depends on where you work in relation to the clinic, you may be able to fit in visits in your lunch time or on the way in or home.

1wish · 01/03/2008 21:00

I'm interested in the work/Ivf balance too. I don't know whether to wait and have two IVF attempts then get a job if it fails. Or go for that dream job i've just seen and just hope it works out.
I mean how much time is spent at the clinic, you would have to tell your employer wouldn't you?

Sorry for hijacking again Jane, and i've had wine now so i'll be worse

jenkel · 01/03/2008 21:00

It was daring and it did pay off but we were taking a huge risk, if it didnt work I would have been left without a job. But I was so positive that it would, which was why it I went to pieces so much when the first one failed, I didnt really go into it expecting failure.

Dont mean to be rude but is money an issue or are you lucky to get funding, when you know each visit could ultimately cost your more that is bound to have a negative effect.

Kewcumber · 01/03/2008 21:00

no help on teh work thing (I also left my job) - when it didn;t work and I had to explain a gao in my CV was bloody dificult though. I scaed the wits out of one (male) recruiters who persisted in asking what I'd done in my year off "I had bloody IVF repeatedly. OK?"

Kewcumber · 01/03/2008 20:58

I was glad I set myself a limit - it isvery easy to keep going until your funds (and your body!) are exhausted, its sooo tempting just to think ... one more try...

Obviously that approach doesn't work for everyone but I knew I would move on to adoption and just felt that wasting more time and money on something which may never work was less important than having a fmaily anotherway.

JaneHH · 01/03/2008 20:54

Jenkel now THAT was daring!!!! Don't think I'd dare do that [scared weedy look] Wow the gamble paid off well. Has anyone else had to do the juggling-work-and-IVF thing? How did you do it?

I will be implementing the no-asking-me rule too It does my head in with well-meaning friends asking me how it's going in the pregnancy department (not knowing that I've been pregnant again). What do they expect me to say? "Well, I'm ovulating on Monday so I'll get back to you on Tuesday morning as to how it went"

Sorry to be a bit behind on posts - everytime I post a message there are three more which have appeared...

OP posts:
JaneHH · 01/03/2008 20:50

Hey kewcumber, we meet again! (Think we were both on some loooong thread sometime last week - either the one about working mothers or with LG&T needing some MN Power!)

Thanks very much for your input. I'm sorry to hear it went so badly for you - very strong of you to make a decision beforehand as to how many cycles you wanted to try. As with my pregnancies, I think DH and I will have to see when we want to stop when we get to that point, as (as you can see from my posts) I have very little idea of what we're letting ourselves in for...

So, so far I think we can consider the following downsides:

  • self-injection
  • hormonal inbalance
  • having to schlep backwards and forwards to clinic
  • egg/embryo/blastocyte counting
  • hyperstimulation (dangerous for me if it happens)

oh and those transvaginal scans (had enough of them when pregnant )

...

anything else I need to be forewarned of?

OP posts:
jenkel · 01/03/2008 20:48

Just to jump in again, going through IVF while working was my main concern, I didnt want everybody in the office to know my very private business and just couldnt figure out how to do it.

We took a bit of a gamble but it kind of paid off, I handed in my notice and we went on a once in a lifetime holiday around the world, I told my very understanding boss the reason for leaving work and when we came back my boss allowed me to do some work on a casual basis from home and once i got pregnant I handed in my notice.

Kewcumber · 01/03/2008 20:33

downregging = down regulating - effet=ctivey they turn all your homrones off (instant menopause) so that the artificial hormones can take over - it takes a different amount of time for everyone but I beleive is about 2 weeks (?) is just a nasal spray.

Kewcumber · 01/03/2008 20:30

"It is hard for IVF not to be the main focus of your life for that time - OK hands up who managed that!

Its tru that as you don't appear to have any fertility issues your chances would be higher again.

I'd also forgotten (my how the memory recedes!) how up and down your emotions were depemdong on the results of the scan. Oh the follicales are growing nicely = happy positive day, oh there hasn;t been much change form the last scan = depressed miserable day. I had to tell my family not to ask me how it was going in the end as it was doing my head in - we developed a rule in teh end - if I wanted to talk abou tit I would bring the subject up otherwise they;d keep their mouth shut!

JaneHH · 01/03/2008 20:29

Thanks LadyMuck!

Am in Holland and will have to travel about 2 hours in the car to get to the clinic where they do the PGD. This combined with a 5-day working week is def one of my worries at the moment! However having told work about my 2 "miscarriages" (not going to tell them the full story) I am hoping they will be accommodating. It's what you tell colleagues when you're nipping off to the clinic AGAIN that I'm really worried about. The last thing I want to be is the department soap opera (oooh she's going for another round, will it work???? etc etc etc)

Very strange to know so much about it all - I hadn't thought of that, but to be honest my first termination was not a D+C and I was induced so I have seen a lot more of the world of obstetrics than I would wish on my worst enemy . Perhaps I will be able to deal with that, I wonder. But please help, what is "downregging"?

And the worst thing? Being able to conceive naturally makes no blardy difference to IVF success rates!! It's all the faffing around with embryos outside the body which reduces the rates of conception, not whether or not you produce "good" eggs or sperm or whatever. This is very annoying - but it does mean I can completely sympathise with others in the "normal" IVF boat.

So - 3 cycles, you think, then take stock?

OP posts:
Kewcumber · 01/03/2008 20:26

II had three cycles of IVF after 6 cycles on clomid and 3 cycles on injectibles - all IUI. This was after a cone biopsy and a polyp being removed.

Bst piece of advice I had was to decide how many attenpts you were going to have and stick to it. I was very unlucky with my IVF. The first I haemorrgaed afetr one week instead of having normal bleed after two. Clnic decided that I wasn't absorbing enough progesterone to suuport a pregnancy so had to move to injectible intramuscular projestone (conistency of olive oil) daily after embryo transfer. On teh days when I didn;t have anyone to stick me in the bum I had to imbed a needle that would scare horses into my thigh up to the hilt It bloody hurt - the normal IVF injetions are easy particlarly if you have very good needles.

Second attempt I hyperstimulated badly and had 30 follicels over 2cms (they didn't bother counting the smaller ones) once I'd ben treated they managed to colelct one egg . Third attempt was painfully slow as they were so concerned about me hyperstimulating again, egg collection was normal but for reasons they don't understand the sperm died before fertilising any eggs.

I found the drugs exaggerated my emotions terribly, I'm not an unusually emotional person but could be relied on to cry in public at the least provocatopn . In the end you stick with it becuase you want it enough. But I think its a good idea to be prepared. If you're under 35 and normal BMI that will work massively in your favour.

Before I terrify you too much, my experince was unusual and the clinic I used said about 85% of the popel they have under 35 are preganant by the third attmept. I also think that the technology is improvig all the time.

Be prepared to become very blase about your body parts though. I've had more transvaginal scans than most women have had hot dinners

1wish · 01/03/2008 20:21

Thanks again jane, and sorry if i'm hijacking .
Coggy have you considered egg sharing? I know it raises alot of issues, but we looked into it and your talking under £1000 as opposed to the £3500 which is our cheapest quote so far.
(Though makes me very angry that women in desperate situations like ours are forced to sell their eggs because of high prices and lack of NHS funding ) sorry had to rant there, realise it's a delicate issue

LadyMuck · 01/03/2008 20:15

Some of the stresses will be the number of visits to the clinics and the timing of these, especially if you are working. The fact that I couldn't predict which day egg retrieval would be was quite a blow in terms of working, so that is something to consider if you haven't already.

The other aspect of the treatment that I hadn't appreciated in advance is that you end up knowing too much about what is going on. You can follow the size and number of your follicles during each scan, then you have the number of eggs collected, then you have the number of emrbyos that fertilise and then you have to see how many of those reach blastocyte stage or whatever is needed for the PGD (and typically the numbers drop at each of these stages). And of course you have the extra step of seeing how many "pass" the PGD. And you go through all of this before you even start your 2 week wait.

The other thing to think about is the length of a cycle. Because of downregging beforehand, from the time you start to downreg to the time of the pg test can be up to 7 weeks. It is hard for IVF not to be the main focus of your life for that time.

I do feel for you in having had to terminate. IVF rates have increased so much and obviously they will be higher than normal for you as you have previously concieved. I'm sure that your clinic will have warned you to consider this as a round of treatments, ie set yourself up mentally to think of having 3 IVF cycles and see what happens.

Good luck!

JaneHH · 01/03/2008 20:09

Yes get some wine down you while you can before you get pregnant and can't do ANYTHING fun anymore Sorry, very flippant on a thread like this. 's just my way of dealing with it all, I suppose. On a serious note - I'm very sorry to hear that you're at risk of an early menopause. It makes my problems seem very small. Good luck with it all.

And Coggy good luck with the adoption process if you go for it - and with private IVF if you choose that route. I hope it works out for you, too.

OP posts:
1wish · 01/03/2008 20:02

And thankyou Coggy (feels star struck )

1wish · 01/03/2008 20:00

Unfortunately I am also near the deadline as I've been warned I'm at risk of premature menopause (sp) Ohh it just gets better doesn't it!!

But your positivity is very up lifting Jane, it helps talking to people who understand. Most people (my mother mainly) cannot understand my anxiety and keep saying I should wait, but it's not something you can easily put to the back of your mind is it?

The one solution to our problem is the cause of the problem in the 1st place (if that makes sense)

I'm off to crack the wine open and think positive thoughts

coggy · 01/03/2008 19:57

Thank you 1wish.....it's amazing how the past years have just turned into 'normal life' really....although I do have my moments when I feel that life is particularily unfair!

On the whole I am positive about it all.
I thought that I would be devestated at a failed IVF attempt as that was The End...but we are now looking into adoption and have found out that a private IVF attempt is not quite as hugely expensive as we thought.....we shall have to see.......

Hope all goes well with you. You have years on your side which is a good thing...although I know it doesn't feel like much of a comfort when you've been ttc for so long.
X

JaneHH · 01/03/2008 19:50

Absolutely everything crossed for you too, 1wish! Can I just say you have YEARS to try yet ( iyswim and if that helps)... I thought you might be a mature student but you have a lot of time yet I think a lot of people get worn out by the fact that they've only got a couple of years before they really can't try and conceive anymore, with that magical deadline of 35+ looming. Despite trying for 3 years (don't forget that the student life can take it out on your body!) you really never know... Take things as they come and who knows, you may just be very pleasantly surprised! (From this little missive you will be able to deduce that I'm slightly nearer that magical 35+ boundary than you ) I hope it all works for you.

OP posts:
1wish · 01/03/2008 19:40

Fingers crossed for you . I don't think it'll work for us, I'm coming to terms with this at the grand old age of 24 after actively trying for 3 years and no contraception for 6 (I know, i'm terrible )
Where are you thinking of having your IVF, are you going private?

Also just wanted to say i'm so sorry it didn't work out coggy i've been following your story for ages, and i've never heard such a heartbreaking story. Makes me feel stupid wallowing in my self pity when I can't even imagine what you've gone through.

I'm glad the IVF may not be as stressfull as I first thought

JaneHH · 01/03/2008 19:31

coggy so sorry to hear it didn't work for you
x

OP posts:
JaneHH · 01/03/2008 19:30

I agree, 1wish, that IS hard when everyone around you is pg. I had that a couple of years ago (DH and I are a bit behind the times in only wanting to get pg now ) but you DO learn to live with it, I promise. Because of the 50% chances of passing on what I don't want to pass on (and because of the even smaller chances of IVF working each time for us ), DH and I have developed a kind of strategy for dealing with the fact that there's quite a high chance that we will never have children.

a) we don't EVER make any plans for where we'd have the nursery etc
b) we don't talk about what we'd like any children of ours to be like (arty? sporty? etc)
c) we concentrate on all the positives of not having children. OK there are not that many when you look beyond the short-term "well next Saturday when we go out we don't have to get a babysitter" and "ooh I can have a glass of wine and eat some paté because I'm not pregnant" but you do have to keep looking ahead to positive things.

Of course we talked a lot about how disappointed we were when we had to terminate the two pregnancies (and that was very important to do, I know) but we do stop each other revelling in a fantasy future which may not even exist for us. That way if it DOES work for us we'll be absolutely blardy over the moon (and surprised!!).

I think all of us starting on IVF will have to deal with the fact that it might not work for us Everyone has to develop their little strategies for dealing with it without repressing their disappointment - I hope you and your partner can [big beam of support]

Sorry, bit of an essay...

OP posts:
coggy · 01/03/2008 19:24

Oops!
I also meant to say...that I believe that this cycle of IVF would have been far more stressful if we had had to pay for it.

The financial implications add a whole new stress level I'm sure....which is why we decided to only have our one NHS go.

Swipe left for the next trending thread