Anyone had any luck with Letrozole?!

Hey I used letrozole for 5 cycles under dr supervision (PCOS never any natural pregnancies) did 2.5mg and 5mg and it worked once at 5mg. Do you know the protocol to use it? I then needed injections to ovulate and get pregnant with progesterone support. A neighbour also with PCOS had letrozole from fertility and it hadn’t worked she had some left when treatment got cancelled and without a dr tried it and it worked and she got pregnant. It’s your choice, you could try it if you think you can do it safely?

Just so confused 😕 anyone feel free to give me your opinion on this should I or shouldn't I could really do with you lovely ladies advice xx

Thank you Victoria 😊 unfortunately the waiting list for the fertility clinic here is terrible your waiting a year or more just to be seen that's before starting any treatments unless you go private then your in straight away but it's so expensive to go private you might aswell save a little more and go for around of ivf I'm just abit all over the place at the moment I feel like it's been a sign silly I know but what's the odds my friends treatment is letrozole she has over ordered and said I could use them and it's for fertility I feel there's a part of me saying no don't do it because something could go wrong but then the others saying try it once it's your last chance especially as my friend is just going to bin the once she doesn't need feels a waste when it's something that could possibly help me

Hi all I'm PCOS been trying for over 10 years first few years I was falling pregnant but kept miscarrying I haven't been pregnant now for about 6 years I tried multiple over the counter things and doctors put me on clomid but nothing I've just about giving up and I now don't see my doctor anymore about it but here gose my friend had breast cancer thankfully removed and she's doing great she's been talking about having kids I'm happy for her so we got into the conversation about her medication and if it was effect her getting pregnant when infact when we did some research we find it's also used as a fertility drug so she then says to me I have over the amount of letrozole as she put 2 prescriptions in so has double the amount she needs and says if you want a pack to try have one of mine and I know so please don't judge me it's the wrong thing to do and you shouldn't take someone else's medication but I can't help but feel like I've been given a chance and feel like I should just try it once but I'm a little worried too I've done research about letrozole 2.5mg and there isn't really any major side effects so would I really need to be monitored by my doctor again please don't judge me I'm just in a very confused state of mind right now and would really like some advice

Hey, I can totally relate to your situation. I also struggled with PCOS and TTC and was prescribed Letrozole at one point. Like you, I had regular periods, and while Letrozole seemed promising, it didn’t work for me personally—I didn’t achieve the results I was hoping for.

After that, I tried Metformin, but again, it wasn’t the breakthrough I needed. Eventually, I decided to give Clomid a try after hearing about it from a close friend who had great success with it. Honestly, Clomid was a game-changer for me! I started taking it on days 3–7 of my cycle, and by the second cycle, I got my first positive pregnancy test! 🥰 I can’t describe how relieved and happy I was.

I actually ordered Clomid from a reliable pharmacy my friend recommended: topsup24.com/buy-clomid-uk.html. The process was super easy, the delivery was fast, and the medication worked exactly as expected. I was really pleased with the whole experience.

Just don’t lose hope. Letrozole works wonders for many women, but if it doesn’t, there are definitely other options out there like Clomid. Speak with your doctor about next steps, and always keep the faith—it can happen when you least expect it! 💕

Wishing you all the best on your journey! 💐

Hi, can I ask if you took progesterone from ovulation onwards for your luteal phase, or if they gave it to you for other stages of your cycle too?

Thanks for this thread guys
Im currently on my 2nd Letrozole cycle

Thank you lovely xx

@Victoriaspa I needed to see that success story. Huge congratulations! Just got my period after month one and feeling very depleted as ttc for 25 months now

My first month I produced 2 good looking follicles, but did not get pregnant. The second month I took the same dose of medication and produced 1 good follicle. I am happy to report that I am pregnant! I have PCOS and am very pleased with the outcome - https://onlinecheappills.com/letrozole.html

@Res_Ipsa i have slightly irregular cycles 26-34 days. They said it could help regulate them more but it hasn’t. I haven’t ovulated on 2.5mg and 5mg also doesn’t seem to be working

I also have mild PCOS but my body was pretty resistant! I ended up having to take 7.5mg before I would ovulate.

Have they also put you on Metformin? There is some evidence that it will increase success rates.

Letrozole is used to induce ovulation, why have they given you this if you already ovulate naturally?

@Alexis7890 update from me…. The clinic want me to take norethisterone to induce a bleed but I’m worried about taking it because we’ve been trying all cycle and only stopped around 5 days ago so technically I could be pregnant as I have no idea if or when I ovulated. The GP suggested I wait another two weeks for a negative pregnancy test before I start it 😭. Im
already CD39 and my cycles without this are totally normal! They have said they want to keep me on the same dose next month. I just don’t get it but I think if they don’t increase my dose then I won’t take it. I don’t want this to happen again

@Victoriaspa it was probably 2.5mg cycle days 3-7. Had one scan mid cycle. Good luck!

@Alexis7890 great- thanks so much for replying to me. NHS wouldn’t give me letrozole as I ovulate naturally so I went private for one last shot before IVF but just feels like it’s made everything worse!

@Hoping43 try a local pharmacy, they don’t sell provera but they usually sell norethisterone and that does the same thing so then at least you can get started on the next cycle! 2.5mg hasn’t worked for me so they’re trying me on 5 next cycle but I don’t ovulate naturally and if 5 fails I’ll go to injectables. I would expect you to be getting top care as it’s private!!

@Alexis7890 It’s private. They gave me 2.5mg. They said I ovulate myself anyway so that’s all I would need. I went for 4 scans between days 9-21 and I had 25 follicles but they were all 10mm or below each time I went. I never had any usual ovulation symptoms but my lining went to a post ovulation thickness. I was only going to do the letrozole for 3 months as a last ditch attempt before we do IVF (this is our third baby) but it’s all gone wrong! I’m worried they won’t do anything and my period will just never come if I haven’t ovulated x

@Hoping43 is this through the nhs? Or private? What dosage did they give you for this cycle? All I can suggest is stand your ground. Norethisterone (not sure on spelling) can be used to bring on a period like provera does and you can buy that in pharmacies I think so could be worth a go so you know the period will come if the consultant won’t help?

I conceived on my first cycle of letrozole after 18ish months of actively ttc. Had not used contraception for another few years before but nothing ever happened. I also had suspected mild pco, even if I did get a positive opk in most cycles.