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Conception

When's the best time to get pregnant? Use our interactive ovulation calculator to work out when you're most fertile and most likely to conceive.

Immune/NK issues - aka Pred Thread no. 22!

990 replies

HappyApple05 · 22/10/2018 21:01

Helllooooo deariesFlowers

Opening this new thread looking for a light in the tunnel during my journey towards conception. Would be nice to walk along with people in the same journey. To cut my story short, 3 miscarriages and referred to Mr.S, diagnosed with high NK cells and lupus positive, already on levothyroxine. After 2 weeks of staring at the med pack, I have now finally started on Aspirin, Vit D and Pregnacare plus. Awaiting Ovulation to start on Pred protocol.

Miscarriage Sad history:

  1. July 2017 - In my 12 week scan, found foetus with no hb (6 weeks foetus size), devastated! Shock Had severe morning sickness, didn't predict anything negative. Took my son (6 years then) to the scan planning to break the surprise where he could see his sibling in scan.. We all broke down, opted d&c
  1. March 2018 - started bleeding in 6 weeks and miscarried naturally.
  1. July 2018 - spotted in 6 weeks, scan at EPU no pole, returned when 9 weeks along, still nothing, opted d&c

Bought the ovu predictor kit for the first time, counting days to use it. Any of you in the same position? Would be great to hear your stories and cheer each other up towards the destination. Previous threads were beautiful, so supportive but sadly the latest post was in Sep 2017. So most of them would have crossed the bridge. Decided to start on a fresh thread.. So here we are....

Looking forward to catching up... Take care you guys.... Plenty of baby dust to everyone

OP posts:
bluepixie · 27/06/2019 13:04

Chicjen we had major sperm problems. None there and all rubbish ones! I put my dh on a ridiculous number of antioxidants (I spoke to dietician Mel about it and she was great in recommending what he needed to take) and saw mr Ramsey who put him in tamoxifen which helped increase his numbers (and I got a natural preg which I mc!) but then our ivf cycle gave us some good blasts. Just worth a thought. We also did tried to do fragmentation test and aneuplody but not enough sperm for it

bluepixie · 27/06/2019 13:01

Hi hopeful sorry not been online for a while!
So I’m on day 4 of oestrogen atm. I usually have lining dramas so will see how things go!
I take Gcsf from day 5 of oestrogen (urs is 3?) and yes every 3rd day. Also on the hydroxy pred Clexane etc. Can I ask when you had your intralipids? Are you also on aspirin? Last pregnancy I had ivig with gorgy (which worked) and I’ve decided not to have it this time. I don’t know if this is a huge error!!! But shehata doesn’t often use it and has good results so hoping it’s ok?!
Good luck for ur lining scan!!

Sunshineblonde1 · 27/06/2019 07:35

Big hugs @chickjen so sorry to hear that, will be very interesting to see what the sperm comet reveals. My fiancé had the antioxidants after the comet results and it seems to have done the trick along with Mr S’s suggestion of having a strategic ejaculation before the baby dance xxx

KittyKatSmile · 27/06/2019 07:18

Oh @Chickjen I'm so so sorry. Poor darling, especially with that rubbish you're having to deal with at work. You sound very upbeat. Stay strong lovely.

Chickjen · 27/06/2019 07:11

It's another chemical for me 😥 The good thing to come out of it is DH has finally agreed to do the sperm comet test 👍 But the guy I sit next to at work announced yesterday his wife is having a baby, great timing!😠 I am starting some CBT sessions next week which I'm quite looking forward too 😀 Hope everyone else is doing ok? ❤️

KittyKatSmile · 21/06/2019 09:08

@Chickjen what's one of the lines here? "A line is a line"?! Sounds like congratulations may be in order. Fingers crossed for no AF today or Monday. Holiday is lovely, just what I needed. Meant to test next Friday, will probably go for Thursday (someone who had the transfer on the same day as me is having blood tests on wed so it doesn't seem ridiculous. It would actually be 16dpo which feels late after months of testing early to ensure you can get those intralipids in). Big love. Great to see you back here x

Chickjen · 21/06/2019 08:56

Wow I didn't check in for a few days and I have missed so much! So lovely to hear from @Nixwix @Sunshineblonde1 @Megan234 with your amazing pregnancy updates, please do keep letting us know how you are getting on. ❤️ @NixWix I can't believe you still don't know! How on earth has he kept that to himself! Does anyone else know?
Great news on your scan with prof A @DaniMERL 😀 And good luck for your scan @Widdendream77 🍀
@Lau2019 I hope today goes as well as these things can, thinking of you Flowers I hope MrS can see you soon and tweak your plan.

I am having a shocking week. A huge tree branch fell on our phone line and pulled it down along with our fascia and guttering, have been super stressed all week organising BT and roofers and tree surgeons 😡 I am day 8 pred with no side effects at all. I did start a few days after O so I tested yesterday and got a positive but I tested again today and there's no progression so I'm not holding out much hope. AF would be due tomorrow with my new weird short cycle, or Monday with my normal. As always totally overthinking this and confusing myself. 😕
@KittyKatSmile how are you getting on, how's the holiday, when can you test?!! ❤️
Hello to everyone I have missed! 😚

Hopeful07 · 20/06/2019 20:36

@Megan234 great news..fingers crossed for u. And i get more confidence that the hydroxy ll do the trick for me too..
@zarala - i ll be having my frozen embryo transfer in 10 days if the scan goes well on monday..Mr.S added hydroxy for me, so bit hopeful..

zarala · 20/06/2019 18:46

@Megan234 oooh! Good luck!! I have all my fingers crossed for a smooth and easy pregnancy for you!!! I'm really happy to see this news !!!

@Hopeful07 thank you very much
Where are you on this journey? Hope all is going well for you!

Megan234 · 20/06/2019 16:51

Sorry I can't find anywhere how to delete the first post x

Megan234 · 20/06/2019 16:48

@Zarala I’m so happy for you congratulations, baby girl how lovely 💗
@Hopeful07 nice to see you back here, good luck with the treatment 🤞
I’m 12 weeks pregnant and having the nhs scan next week and the following week scan with the prof🤞 This time Mr S added steroids to my treatment as well as Hydroxy. I’m still nervous, but hopefully things will progress in the right direction.
Warm welcome to the new ladies here, Mr S makes dreams come true, don’t give up Xx

Megan234 · 20/06/2019 16:18

@Zarala I’m so happy for congratulations, baby girl how lovely 💗
@Hopeful07 nice to see you back here, good luck with the treatment 🤞
I’m 12 weeks pregnant and having the nhs scan next week and the following week scan with the prof🤞 This time Mr S added steroids to my treatment as well as Hydroxy. I’m still nervous, but hopefully things will progress in the right direction.
Warm welcome to the new ladies here, Mr S makes dreams come true, don’t give up Xx

Hopeful07 · 20/06/2019 10:50

@ zarala - Many congratulations!! Amazing news..remember u and meghan from old threads..

DaniMERL · 20/06/2019 07:29

Amazing to hear from you @zarala! Many congrats to you too. I have been thinking of you.
All good here, the scan yesterday went well. DD is 23 Dec! xx

zarala · 19/06/2019 23:04

@DaniMERL & @Megan234
Hey ladies

I just wanted to comeback and check in with you guys! I had to leave MN as I just wanted to have positivity around me and not dwell on what I had been through with my losses - so I'm sorry I disappeared

also I wanted to say I gave birth to my little rainbow girl on 5/5- she's 6.5 weeks now and she's just wonderful!

After three losses Dr S's protocol worked for me! And I couldn't be happier or more grateful

I remember how much hope it gave me when I read success stories on here so wanted to come back and share mine.

I'm also so happy to read that you're pregnant @DaniMERL !!!! Amazing!!!

What's @Megan234 News!!? I couldn't see a recent post from her ?!

Good luck to everyone on this thread
And I hope you all get your rainbow babies

💕

Sunshineblonde1 · 19/06/2019 20:21

Aww that is so lovely to hear @KittyKatSmile, I feel the exact same!! X

KittyKatSmile · 19/06/2019 20:13

@Nixwix @Sunshineblonde1 so so good to hear from you both and to hear your updates. All of you ladies were the only thing that got me through those very dark early days post mc 4. I am feeling so zen and at peace these days, I hardly recognise myself. Lots of love to all of you x

Sunshineblonde1 · 19/06/2019 19:54

Hey @nixwix lovely to hear from you my dear, so pleased all is going swimmingly, I think we are Due Date Twinnies arent we and we are house hunting too :) I am 25 weeks this week and really enjoying the second trimi. The 1st wasnt so great but I havent looked back since 12 weeks - time has just flown and we are babymooning next week - last 'adults only' hol until my hen next year wahoo! Baby is kicking lots every day but bump hasn't quite popped yet which is good as I can still get in the gym every day. @Nixwix like you I am already thinking of potentially having a second, it would be so nice to have a sibling for this little bubbin if I can squeeze another in!! P.S. All my friends who have gone through IVF fell pregnant naturally after!! I don't know what it is, it's like it resets something internally!?! I'm starting the antenatal classes in August and really must ring NCT to start that too - ive heard nothing but good things. Pregnancy Yoga has been so helpful and informative and has helped me to bond with little lady.

All in all I personally cannot thank Mr S enough for bringing his theory, tests and the protocol to the UK and I am positive all ladies here will have their rainbow babies soon - you are all on the right path whether its through Mr S, IVF clinics or other care. Sending all so much love and positive thoughts - you are all amazing for tackling this conception journey - don't forget to be kind to yourselves for achieving what you have already achieved in your individual journeys. The tests and research and the uphill struggle will all pay off. And make sure you treat yourselves regularly!!! You all deserve it! Big hugs!!

I am so pleased to see so many new BFP's since I last checked in. Amazing progress @DaniMERL - you made it!! Hope you found Prof A as AMAZING as we do :) and @Chickjen how how you my lovely??Don't worry too much about your cycle changing. After my last D&C my cycle went from 25 days to 31days to 27days - I actually preferred the shorter periods. Accupuncture helped to regulate my cycles. Oh and yoga and breathing - I adopted the 'think less, breathe more' approach to get me through the anxiety of the protocol and first trimi. It was my salvation!

@KittyKatSmile best of luck with your run of IVF lovely and to all those who are currently pregnant - HURRAH THIS IS IT!!!!!

@HappyApple05 not sure if you still check in from time to time but I have been thinking of you and hope all is well. You must be past 12 weeks now. Hope all is well

Keep the positivity going ladies this thread is an amazing resource.

x

DaniMERL · 19/06/2019 08:42

@nixwix thank you so much and lovely to hear from you. Amazing progress!

I have my scan with Mr A at the clinic this morning, looking forward to that.

xx

Nixwix · 18/06/2019 16:34

Hi everyone. I used to post quite regularly but haven't had the time lately. Somehow pregnancy, family visits and house hunting got me very busy.

Just want to say hi to all the new ladies here and anyone under Dr S' protocol. Good luck!! So happy to see that some of you got your BFP. Please keep posting, always reading even if I am not posting.

Just want to wish you @DaniMERL congratulations! I hope you 12 week scan went well. And your harmony test results are all clear - so amazing! @KittyKatSmile how did your embryo transfer go? I rmb mine, two men and two nurses looking at my down- had me laughing inside. How are you @Chickjen !! And @Sunshineblonde1 would be great to hear from you and how you are getting on. Hope all's well with you and little one!

As for me, I am 24 weeks and still don't know the gender! So far so good, baby moves quite a bit. Had my whooping cough vaccination recently. And booked antenatal classes although I am keen to book NCT ones so my husband can join! Anyone else starting antenatal classes? The odd moments of anxiety are still there but trying to stay positive! :)

This sounds crazy but I am thinking of next pregnancy already as I'd like to conceive naturally! So anyone out here who tried ivf and then got naturally pregnant? (With immune issues)

Xxxx

fertilityhelphub · 18/06/2019 16:07

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Hopeful07 · 17/06/2019 11:58

@KittyKatSmile - great ur embryo transfer went well..not sure whether u can take melatonin now, its better to check with ur consultant. I have to take 25mg this time, its weird the body reacts to it each time differently. Hope ur sleep pattern gets better and u can relax a bit in ur 2ww. Good luck

Hopeful07 · 17/06/2019 11:49

@Lau2019 so sorry to hear about ur loss. I know exactly how heartbreaking this would be. I also had my 7th miscarriage after being in Mr.S protocol, was very hopeful that it would work for me. Unfortunately we seem to fall in the very less category where pred dont work. Please dont lose hope and as DaniMERL said book for a review and if u re ready try the hCQ protocol. I got to know from other forums as well that people have got success with hcq after failing on pred. After losing hope, I have now gained some strength to try with hCQ and gcsf and hoping for some success.
Please dont lose hope. take carexxx

KittyKatSmile · 17/06/2019 11:27

@Hopeful07 same dose, yes. It's usually 4am for me too but last night I couldn't get to sleep and then was only asleep for 40mns before waking up again. I ended up taking a melatonin which tided me over to 6:30am but I've just had my embryo transfer today so don't know if it's still safe to take. I never had this before and I was on 25mg then!

Hopeful07 · 17/06/2019 11:25

@Cream123 - i m day 4 on oestrogen today. had my down regulation scan last friday, all looked ok so started on oestrogen. Will have another scan on monday 24th and then ll know the transfer date. Probably ll start taking my first G-CSF injection coming tue/wed. Bit later than your protocol..Hav u been told to take every 3 days as well?
and have you started taking g-csf? Glad to find someone wtih a similar protocol.
@KittyKatSmile - How much dose r u on? I took 20 mg last time and like u was wide awake from 4 am. Taking it bit early helped me but still had disturbed sleep. soon ll be starting to take it again now!!
@Chickjen - good luck on your journey.hope this s the month for u.Take Care xx