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Conception

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Immune/NK issues - aka Pred Thread no.20!

960 replies

harrietm87 · 18/07/2017 11:42

Hi all, thought I'd get the ball rolling on the new thread.

Welcome all with immune/natural killer cell issues.

It's been a while since a new thread so thought it might be helpful if we all added our stats:

I'm harriet, age 30, TTC#1.
3 mcs (2 at 5 weeks, 1 mmc at 9 weeks).
Hypothyroid and high NK cells.
Cycle 2 on pred!

OP posts:
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Tee4me · 04/08/2017 19:35

Ouch Luna! I suppose we are lucky with 7am. We have always used the gro clock, which has been amazing, DS knows he has to wait for 'mr sun' - thoroughly recommend if you're looking for a longer lie in! x

LunaB · 04/08/2017 18:28

7am?? Tee you lucky fox... I've been getting 5:50am wake-up calls 😱😱 Maybe I'll send mine away too, during my baby making bonking

Tee4me · 04/08/2017 15:24

Ah that's a shame about delivery difficulties, good luck tracking a FRER down!
Ha! Banishment at this point in time is a massive bonus! ⛔️⛔️⛔️ We don't often manage morning bonks, what with a 7am intruder! Definitely want to cover all bases for my first month on pred!

PoppyJ1 · 04/08/2017 14:59

Tee4me, thanks! I'm very curious of course! Sadly Amazon Prime won't work here (in West Africa for DP's work) because we have major problems with post and deliveries. I emailed the doctor back at the local clinic and asked him where I can get FR and Clearblue, because they are around!

Sounds like you are well prepared indeed for O day! Love the banishing of child in the interests of minimising disruption to V. important schedule 😂 Good for you on the exercise too, I'm just sitting here getting bloated 😂

Also wanted to add, congrats on your excellent progress Jaffa! 25 weeks! I feel about this the way I saw year 11 girls when I first went to secondary school! Awesome.

Also so pleased to see our thread came up in the trending or active discussions widget, attracted more newbies and returners 😄 Welcome!

Tee4me · 04/08/2017 14:46

Poppy this is very exciting! Be lovely to hear more good news on this thread! Are you an Amazon Prime customer? I get all my TTC bits from there, quick delivery and discrete.
Harriet I'm currently CD5. Usually ovulate CD13 (next Saturday), already booked DS in for a sleepover with his Nanny on the Friday 😂 Been on Thyroxine for over a week now, so hoping it's kicked in fully by the time the egg drops. I've ordered an exercise bike to keep myself lightly active.
This is definitely the most positive thread with most bumps I've stumbled across, very encouraging!! x

PoppyJ1 · 04/08/2017 11:09

Harriet, I'm 8dpo today. Thinking of testing on Sunday or Monday if I can stand it! After that I won't be able to tell DP face to face. Got to see if I can find a reasonable pregnancy test out here! I got up for the loo twice in the night then first thing this morning. This is very sudden! Tingly nipples and still creamy cm so I feel like I have more tangible symptoms than last time.

Please divulge what was enjoyable about the intripalids, I am very intrigued! And glad you've had a positive few days.

harrietm87 · 04/08/2017 10:54

Aaahhh poppy so exciting! Very interesting on the progesterone level. What dpo are you today? I was sure you would be testing earlier than Monday too! Yes I did get left side twinges. I know I ovulated from my left side this time too, though in my last pregnancy it was from the right ovary and I still felt it on the left!

jaffa and snoopy so good to hear from you - congratulations!!! I wonder how @pickledsausage is doing?? Snoopy you're so close now - good luck!

tee and amy that's so annoying they messed up your tests. When are you starting the meds? Fx for more good luck on this thread!

justla yes I agree - intralipids were actually quite enjoyable! (Once I got over nearly passing out when it went in). There was just one other lady in there and we did have a good chat. The midwife is so lovely.

OP posts:
PoppyJ1 · 04/08/2017 10:30

Thanks, Luna ☺️ You are not "barren!" Enjoy the wine, It's a shame we can't have it in pregnancy to keep us calm!

JustLa, yes basically, if the blood test caught the other hormone and mistook it for progesterone the result could be 10% lower. However, the Pred is meant to suppress that hormone. All very interesting. DP can't believe I didn't get the blood test to double check pregnancy but I cannot be bothered to go to the clinic only to be told in two days time that it was too early. It'd be almost POAS stick by then.

Harriet, getting left side ovary pinching today, just like you did 👍

LunaB · 04/08/2017 09:10

😝🤞💝 jaffa - great news

jaffacakes16 · 04/08/2017 08:15

Hi just dropping in to say hi to everyone here, haven't been on in a while. All is going well with my baby growing I've made it to 25 weeks which was a big milestone as I know there's a chance the baby can survive from this gestation. So all of you suffering through the big fat faces, night sweats, nausea and other nasties stick with it!

LunaB · 03/08/2017 20:40

(But I will quickly say... poppy 🎉)

JustLa · 03/08/2017 20:39

😂 Haha Luna! Get it all in ya 🙌🏼

JustLa · 03/08/2017 20:38

Oh that's interesting! With regards to the Pred effects, not that I know Poppy but anything is possible. So your related hormone overproduction could be responsible for your results being 10% above the top of upper end?

LunaB · 03/08/2017 20:37

I will read everything properly tomorrow... until then, "cheers moongirls" - I've been feeling like 'barren woman walking' all year, so I've soothed myself this Thursday eve with 3 glasses of Rioja and am feeling ready for the Roids, the sex, and hopefully... Elvis 🕺 👆

PoppyJ1 · 03/08/2017 19:22

Good grief! Just got my blood test back early. Progesterone is 64.01! Apparently anything over 15 indicates proper ovulation. Doc said upper limit of the reference range for this point in my cycle is 59.01. He said I can go in for a blood test to check for pregnancy or just wait a few days for the ruin one. I've said I'll go for the latter because I can do that at home. I do overproduce a related hormone that can cross reference with progesterone but only by about 10%. Does Pred affect progesterone in the blood?

JustLa · 03/08/2017 19:19

Tee, I really think you'll have success!! He may recommend super ovulation to really get you going but I'm sure he will get you there within a few months and hopefully sooner xxx

JustLa · 03/08/2017 19:17

Welcome back Amy.
Sorry your results have been a bit stressful for you. Hoping you get news of a nice strong egg count to give you a boost.
I'll be your Steriod-Fragmin sister if you decide to go ahead. I've been 'shooting' fragmin for over 5 weeks now and think I've got some good tips to share when you're ready to start 😊
My initial sticky blood results came back as very high on 2 tests, (this wasn't long after a MC operation so I think they should have considered that) I retested and still high on 2 counts. If you have any questions or worries on it, let me know and I'll try to help :)
The intralipids are fine, and that's coming from someone who had one vein collapse and the other flare up so we had to stop. I doubt they've ever had someone with problems like that before and I still didn't mind it. My 2nd lot went swimmingly well, I honestly find it quite enjoyable once it's in and dripping away. You get to talk to the nurse about all of your preggy concerns which is a fab opportunity and you get to chat to other ladies in similar positions.
Just drink lots running up to it and you'll be fine. #BetterThanASmearTest

Harriet, glad he upped your cyclo and didn't realise you were on aspirin. Did you get chin wagging to any other ladies in the treatment room? So pleased to hear Mr S is confident in your bean baking, take each day at a time as every new day increases your chance of success and look how far you've come in the last 2 days!

Glad everything is going well for you too Drttc, hope you're getting a little rest despite looking after a little one 😊

Snoopy how exciting! Well done on the fab job you've obviously done making a baby. Excited to hear the next update!

Poppy, roll on Sunday! (No pressure lol)

Xx

Tee4me · 03/08/2017 19:12

Not cool at all considering the costs involved. He was very apologetic though and produced a stack of email correspondence where he had escalated to the Manager.
In all honesty I'm chomping at the bit to get started on the steroids. We've been trying for 20 months now and in that time have been doing yoga, tai chi and acupuncture. All of which I think are beneficial (especially the acupuncture), but I think I'm beyond the wholly 'natural' approach now, and totally ready to accept the new strategy. I'll still be drinking my daily nettle tea, keeping stress to a minimum and focusing on mindfulness, but I'm totally convinced that Dr S is my answer. Eekkk could be in for a fall, but so encouraged by everybody here x

Amy2017 · 03/08/2017 18:50

Poppy - I had the HS8 test today which includes FSH, LH, E2 and AMH. Thanks, yeah it's so freakin' hard to wait for results - blood or pee stick time! :(

PoppyJ1 · 03/08/2017 18:38

Amy, welcomed back and thanks for your applause on the Africa trip! Which tests did you have? They are very scary to wait for aren't they? I had AMH done recently amid concerns about my egg reserve but it came back excellent instead. I had to wait a week on the NHS, so I'd expect yours to be much quicker.

Amy and Tee4me I can't believe all this you have had to put up with re losing samples! The waits for fertility related results are bad enough without incompetence!

Snoopy, so close now! Love your comment about the state of the house! Looking forward to a happy update soon!

Amy2017 · 03/08/2017 18:21

Oh wow, not you too Tee. Not cool at all with all this money we're paying. Have you decided to get started of treatment straight away?

I was thinking about going full tee-total-mind-body-hippy-earth-mamma for a few months and try a few natural cycles on an anti inflammatory diet... But if this egg count test comes back with dismal news, I'll probably dive straight into the steroids. I'm still worried about them and the intralipids, despite the reassuring stories on here.

I guess I also need to add Fragmin too now that I have this sticky blood result... !? Gah. So much to think about.

Tee4me · 03/08/2017 18:09

Hmmm Amy, I had a scare with the clinic when they first took my bloods. My blood clotting came back severely abnormal, and had to go back immediately for a retest. Turned out to be an error at the lab. Then when I collected my results Dr S informed me the lab has lost my Thyroid test and had to get that redone too. Annoying as that came back abnormal, which meant I missed out on a few days treatment. Doesn't fill you with confidence does it?

Snoopysimaginaryfriend · 03/08/2017 18:05

Hey everyone. Just popping in quickly to say hello and wish everyone the best, so much happening on the thread at the mo it's amazing!

Today is due date! But baby isn't even engaged so couldn't even do a sweep. Not used to this as edie was a spontaneous labour at 40+1 haha but our home is still a building site so maybe it's for the best.

Amy2017 · 03/08/2017 17:47

Hi ladies! I've just spent the last hour and a bit catching up with everyone's news. HOLY MOLY this thread is a such a rollercoaster!

Harriet - I was so so happy for you, followed by frightened for you, followed by relieved for you! I'm sending all the good vibes for a sticky bean.

Seeking, Trying, DrTTC and JustLa - mega healthy sticky bean good vibes for you all too (and anyone else I missed!).

LunaB - "By the power of our moonfaces we will succeed! 🌝🌝🌝"

PoppyJ1 · 03/08/2017 17:03

Thanks, DrTTC. Light cramping sounds ideal; proof that something is happening but whatever it is is normal and not unpleasant.

I have to say, I am pleased because I was cramping and spotting by 7dpo last cycle and cramping by 5-6 dpo the cycle before. I've had a few very light cramp and lots more creamy cm, which is not normal for me, so it's looking promising.

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