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Immune/NK issues - aka Pred Thread no.20!

960 replies

harrietm87 · 18/07/2017 11:42

Hi all, thought I'd get the ball rolling on the new thread.

Welcome all with immune/natural killer cell issues.

It's been a while since a new thread so thought it might be helpful if we all added our stats:

I'm harriet, age 30, TTC#1.
3 mcs (2 at 5 weeks, 1 mmc at 9 weeks).
Hypothyroid and high NK cells.
Cycle 2 on pred!

OP posts:
Thread gallery
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JustLa · 18/08/2017 16:35

Yum Luna!! Looks like aphrodisiac food if I ever saw it!

Harriet, I had fish n chils followed by warm brownie at a restaurant on weds, my stomach was so bloated it hurt! Although the fatigue is annoying I feel like it's your body saying 'right you, slow down- I need to concentrate on making a human and I wanna get it right. I need all your energy please 😊'

Seeking, lol at your knicks comment.
Hope you're starting to relax a teeeeeeny bit more?

Take4, welcome!! You are not too old at all. We were just talking about Ginger spice kicking another out with no help but acupuncture at 44 and thinking of another and she's young compared to many.
I went for my dating scan today and I would say around 20-30% of the expectant mums there looked well into their 40's which I thought was great! So many older mums are awesome mothers, not only because they take the responsibility so seriously that they've waited for ( not that young mums don't ofc, but you know what I mean)

I'm currently sobbing my silly hormonal eyes out, mid writing this I got a call from Mr S office, harmony results came back low risk 😊 Also had my 11+4 nuchal and dating scan at hospital today and they dated my at 12+2! That's 5 days less of pure panic in my life!! Dare I dream this could be it?! Eeeek xxx

LunaB · 18/08/2017 14:58

Welcome take I echo Poppy's comments - there's no time or age or sadness limit here!! ❤️❤️

Harriet - 🐷🙌🍝🍝🥘🍟🌮🌯🍕🍖🥙🍲🍙 (but I'm not even pregnant, just pure piggy)

PoppyJ1 · 18/08/2017 14:45

Welcome, Take4. Sorry for your losses. Don't be embarrassed! This is not an easy journey and perceived time limits make it even harder. I have two female relatives who had babies at 43 and 45 and a friend who had her only child at 48 (all three kids perfectly well) 👍

Take4 · 18/08/2017 14:26

Joined yesterday and not quite up to speed with posting but here goes.

Jessica
Just 43 (old! I know! Feel embarrassed that even still trying!)
3 miscarriages, two early and one Molar pregnancy

Diagnosed with high NK Cells and am under Dr Shehata. Just completed first cycle of prednisolone etc but am also taking Hydroxychoroquine with a view to possibly stopping the steroids but am worried this form of treatment won't be as effective.........

Trying to stay positive and get in the flow of being a pill popper!

Grateful to have found others on the same journey - one that can be very lonely.......

harrietm87 · 18/08/2017 14:21

Mmm luna my mouth is watering! I had fish and chips for lunch at 12 and I'm having curry for dinner...but don't think I can wait that long!!!

I don't know if it's pregnancy cravings or just greed but I've also become obsessed with pasta - eaten it every day this week so far. God help me 🐖🐷🐽

OP posts:
LunaB · 18/08/2017 08:45

Fuel for boink fest (or at least that's my excuse) 🐷

Immune/NK issues - aka Pred Thread no.20!
Seekingmiracles · 18/08/2017 07:52

Hi panda,
Sorry you've suffered loss too but I hope you find comfort in knowing you're not alone. I agree that MrS would be a great place to start to get some kind of plan in place.

Just I'm sure the weight gain will level out once you're off the pred. I've put on about 7lb because I can't stop eating!! I'm actually thinking of re-starting slimming world loosely to regain some kind of control. I worked so hard to shift the baby weight from Tallulah that I really don't want to end up looking like a pygmy hippo!!

I'm of the mindset that they shouldn't even bother with a tummy scan until 9/10 weeks. They hardly ever see enough, they have to do purely for protocol. But all trusts are different. I asked at my last hospital for them to go straight 'in' with the internal and they said they weren't allowed. I'm so used to the internal wand now, that like Harriet, I'm practically whipping my knicks off before I'm even in the room!!

Glad you have you're appointment with prof Quenby soon sheepy.

So glad everything is ok after your bleed stuck. Mr S is of the opinion that a positive scan at 10 weeks is VERY positive. He says most of the time a missed mc at 10 + weeks will show that baby stopped growing around 6/7 weeks. Rarely do they stop growing after 9 weeks. Which is why I think he likes to scan so often.

harrietm87 · 18/08/2017 07:19

Ha ha luna the moon and pig sum me up!!! Haven't had any extra hair yet though thank god. My pred symptoms have been hunger, weight gain and bloating. The bloating is a killer as I'm fat enough at the start of the day but then twice as fat by the end! Had an actual bump last night!

justla I've had the odd wave of nausea but it passes quickly. And I'm exhausted and sleeping loads, though apparently progesterone makes you drowsy so that's probs why! 8lbs does not sound bad at all - dread to think what it is for me - and I'm sure won't affect the little one in the slightest. Good luck with today's scan!

redpanda welcome. I have hashimotos too and had 3 early mcs. The NHS weren't interested in any link between the mcs and my thyroid because my TSH levels were good (I've had it since 16 and well-controlled) so I had private tests with Mr Shehata and he found I had aggressive NK cells in addition to high thyroid antibodies. Everyone with hashis has high antibodies (that's what hashis is) but I think my losses were caused by the combo of that and NK cells. Apparently NK cells can be triggered by a pregnancy so it's common for people to have a normal first pregnancy and then have mcs after, which may have happened in your case? Now I'm being treated with prednisolone and intralipids and it's still so early days but I'm 6+2 and have never got this far before and I'm sure it's thanks to the pred! Mr S is expensive though and you've only had 1 mc (sorry don't mean to minimise how awful it is in any way) so there's every possibility it was just a one off. If you can afford it (tests are about £2.5k) then I'd see Mr S, but also may be worth trying again? NK cells also seem to fluctuate - after a predded up pregnancy drttc is now going drug free and it's all good!

stuck so glad it's all going well!

OP posts:
LunaB · 18/08/2017 06:39

Hairy moonface piggies unite 👨🏻🌝🐷❤️

JustLa · 17/08/2017 23:20

Luna you're so right! And thanks for your lovely comforting words 😊
I would post a pic of my super gut, but wouldn't want to offend anyone. Just started taking fibogel and guess what... that critter bloats you at first too!!! Violet from Willy Wonka better move over, there's a new ball of bloat in town 🐡🌝🏀🎈😂

Stuck, yes pred solves it again! I have a theory that NK cells actually don't exist, but just having pred usually sorts whatever mystery issue you have, out .... lol

Xxx

Stuckinstressville · 17/08/2017 22:14

Hi red - am sorry for your loss.
I have hashimotos too- hence why I think my rmc shoved me on pred the moment I realised I was 7 weeks pregnant. I was advised though that my tsh ought to be sub 1 to ttc and to test frequently when pg. I am
Ever so
Slightly over medicated on levothyroxine to keep my tsh so low. What has your dr said?

LunaB · 17/08/2017 21:53

"Fertility Botherer" 😂😂😂

Bugger, Just.... but at least you have scan tomorrow to put your mind at ease. God you're so close to the magic 12 weeks! Feels so far away for so many of us!

I was very, very bloated and constipated and moonfaced at 12 weeks with DS and I hadn't taken any meds!! It will level out and there's nothing to worry about. We are extremely low risk in the lifestyle stakes - it's just so unlikely you would damage your baby with the type of preg pudge you get 🙃

Sheepy1980 · 17/08/2017 21:53

I am already on Predisnolone am on a 20 mg Maintainance dose, and 300mg Asprin folic acid. I am hoping she accepts me onto the course. I am due Af next week so the charting will happen. I use ovia but if anyone has any suggestions let me know

JustLa · 17/08/2017 21:36

Another thought RedPanda, you could call Mr S's practice in Epsom, Surrey. Many of us in here are on his treatment plans and it may be worth asking if he can treat your particular condition. He's not cheap but his success rate is pretty bloomin good

JustLa · 17/08/2017 21:29

Welcome Panda! Sorry you've had a loss but glad you found us here.
I'm afraid I don't know about your condition but are you taking anything for it?
It could just be a chromosomal MC, but I agree, worth looking into your condition to prevent any future problems

Xx

JustLa · 17/08/2017 21:24

Stuck!! I'm so glad you're still ok, you must be a ball of nerves after the bleed and the pred and cyclo intensify that stuff, ugh. Are you getting them monthly? Some women continue to have monthly period style bleeds throughout pregnancy, would be good for you to know if you are set to have another 'harmless' bleed.
I agree with Luna, we are all in here supporting each other, if you need to 'wobble' at anyone, just let loose.
When is your next scan?

Poppy, it sounds like a cute set up you have there! It's lovely that you get on with their Mum and that you're already a parent in so many ways 😊 and I bet you're awesome at it!

Harriet, how are you feeling? Any effects from pred? Is your tummy big? Salt cravings? Any morning sickness? (mine started at about 7-8 weeks I think) I look about the size of a typical 5 month preggy woman now, the bloat is so uncomfortable and contributing factors include pred, Cyclogest, Heparin, constipation, weight gain and just being pregnant. I've put on about 8lb and hoping it's not unhealthy for the little one.

Tee, only a few days until testy time!

Drttc, not long until scan on Saturday! Will be nice for you to get a date. How have you been feeling?

Good news on Quenby appointment Sheepy

I'm going for another nuchal/dating scan with NHS tomorrow (I'm 11+ 3 today) Did too much strutting around today and had womby pains and strong cervical aches so obvs that's enough to send me into a tizzy!

Hope everyone else is ok :)

PoppyJ1 · 17/08/2017 21:17

Welcome Panda, new very to have another newbie onboard! Love that this thread has so much exposure now on Mumsnet.

Stuck, what a relief but sorry to hear about the terrifying events in the run up to your scan.

Luna, exciting! Looking forward to an update! Still waiting for September window and DP sweetly pointed out last night that he acknowledges his job is badly timed for TTC and he hopes it's not bothering me too much. Feel like less of a fertility botherer now because I have kind of bullied the poor man at times 😳

LunaB · 17/08/2017 21:13

Hi red! Never too late!! Welcome!!! Can't help with your particlaur issue, but I know some of the girls can!

I'm sorry you recently miscarried and hope that you find this group comforting and useful! 💪💋

RedPanda25 · 17/08/2017 20:55

Hi everyone I hope you don't mind me joining? I'm currently TTC again after a miscarriage in June when I was 7 weeks pregnant. I already have a DS who is 18 months old now. Since having him I was diagnosed with Hashimotos and my levels were good before conceiving, below 2.3. I'm so worried that my miscarriage was something to do with my thyroid. Sorry I'm late to the thread but have scrolled back a bit and wanted to say congratulations to those of you who are pregnant and sending luck to those TTC!

LunaB · 17/08/2017 20:45

And sorry the Pred is so shit!! Funny how it affects people differently!!

tee glad you are still feeling ok on it! Test in T-minus 5 days! 🙌 - us soon Poppy & Sheepy ✊️

Hope all the rest of you preggos are well!

LunaB · 17/08/2017 20:43

Hurrah stuck!!!! A-mazing news - what a horrible scare with the bleed but so wonderful another of our pups has made it through these little bleed dramas!!

Stay in touch, we are here for you - enjoy the wedding ❤️❤️

Stuckinstressville · 17/08/2017 20:31

Snigger . Bonk fest! Bf!

Stuckinstressville · 17/08/2017 20:30

Hello! Just burst into mega hormonal tears that you thought of me! FlowersLuna and others

Just read back and still am in awe at how positive and resilient you wonderful crew are. The pred is pretty bad on my health , starving, insomnia etc normal?

Am ok- another mega bleed last week and eating all the food - joy of pred! But had my bi weekly scan on tues and even though the bleed was big and tmi clotty - baby was in there! Looking like a baby alien but still happily kicking and bucking. Am 10 weeks tomorrow .... never made it past tomorrow with my mmc without knowing things had failed and waiting to mc, so am
A bundle of nerves.

Off to a wedding in wales tomorrow for the weekend! Will be good to be distracted!

Tee4me · 17/08/2017 20:18

No noticeable effects Harriet 😬💪🏻💪🏻
I'm on day 6, no moon in the mirror just yet 🌝🌝🌝

PoppyJ1 · 17/08/2017 17:11

Ah, no, I just meant the girls. The eldest is a boy and he's already a teenager! He's lovely too, but doesn't get into the pregnancy conversations! But yes they were certainly busy for a while and had them fairly young. DP and I are both mid 30s.

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