Immune/NK issues - aka Pred Thread no.20!

Agreed Tee.... ooooof, hectic tho

It's a difficult balance isn't it! It also dawned on me that you wouldn't want to start it too late, as although you'd be further along by testing date (= more chance of a genuine FRER result), that would also mean starting the cyclogest later than potentially possible! So as with everything ttc, feels like we're walking on a razor blade, although the reality is that a day of 2 either side is not going to be the make or break! 🙈🙈🙈

I'm holding my nerve take4... will take at dawn on day after solid face lol 🙌

I also had someone tell me I should be happy with the child I have, sheepy.... & I should adopt.... I won't write what I told them in response 😝🖕

Yay! Another wee heartbeat!! Did you whip ya knickers off 👉😝❤️❤️❤️

Thank you for the warm welcome to the group and all the encouragement - means a lot!

JustLa thanks for the reminder about Gerry, Made me smile. It ain't over till it's over and I am a bit younger than her!!!

My question re ovulation and taking pred has been answered without me asking! This month (first cycle on treatment plan) I took pred on first day of solid face but wondered if it should be the following day and it makes sense that it should be.......next month it should all feel less messy and simpler...!

Hope you're all having good weekends x

Hi ladies! Just a quick update - not been able to read everything! Had a scan today and it went perfect! Heartbeat and am caught up with my LMP measuring 6 weeks +4 days. Very happy and very nauseous!

Justla sounds sooooo lovely that you'll be finding out gender with DH for his bday!!

Luna, the Drs when I had the d&c were shocked, which is why the one dr wanted to help so much. That he has actually personally written his own letter to Professor Quenby. I have been looking into Mr S as well.
I was asked on return to work interview why I keep on trying so much and surely I should just be content with DD, and adopt but dh and I looked into it and we actually were told we were too large.

Interesting, you think even day after solid smiley Seeking... glad you're feeling much more confident and calm 😁

Sheepy, I still can't get over how many you've lost... 😰

I agree that you should probably wait until the day after a solid face. You're likely to ovulate with 24hrs of a solid/positive opk. You want to be able to take the pred as long as poss before testing and taking it too early would mean stopping it early.

Welcome take4, sorry for your losses. But you've found a great thread for info and support.

It's my understanding that the NHS don't test for Nk cells. I had all the tests they offered and then went loaded with those results to MrS so I didn't have to pay unnecessarily for tests I'd already had.
While I know it's terribly unfair that they don't test, I do understand why they don't. I do believe though that it will be something that develops as the private industry gather more and more positive results. Treatment on the NHS requires blind testing and quite frankly I don't think many of us would be willing to risk a pregnancy with possible placebo drugs required for blind trials.

I am feeling more positive now. I think once I've got the next scan out the way I'll start to really believe it.

Great news regarding your low risk Just!! You must be so relieved!! Although I do think you should let us know the sex

The NHS are shocking, it is only this time I have had the referrral and the help. But part of me thinks could this only be happening now due to some extremely monumental errors.
I am Sheepy, I have had 14 miscarriages and I am now eagerly awaiting my appointment with professor Quenby. I also have Antiphospolipid Syndrome and Lupus and Fibromyalgia. My current meds are diverse
Duloxetine 120mg
Plaquenil 400mg
Predisnolone 20mg
Asprin 300mg
Folic Acid
B12
The pred has been since last Miscarriage. Currently waiting for AF to show as had D&C and can also start charting properly

Cheers Tee, agreed!

Wow I've missed a lot, this is a fast moving thread!! Welcome newcomers, it's so reassuring to join a thread with so many success stories! I'm in the middle of my first cycle of pred, so gaining so much insight here!
Just that's amazing re. your scan results!! So happy for you. I'm sure none of us will ever relax entirely in pregnancy, but reaching each milestone must be such a relief.
Luna I agree, solid face sounds like a good bet to me! Funny, I ended up ovulating earlier this month too, our bodies are chomping at the bit!! 😂

Anyone interested in visualisation? I've been setting aside some time in my 2ww to just completely relax and focus on my body accepting a pregnancy. Posting my favs 2 here. First is 18 mins and REALLY relaxing and calming. The second is just 5 mins so better if you're pushed for time and not necessarily wanting to get into 'the zone' so much, I like the positive affirmations in it x

Awwww & what a bday treat DH will have today! Just I'm so happy for you guys! Enjoy Devon!

I normally loose them early early, 5/6 weeks, so being on the Pred at the right time seems really vital to me. I get the logic re solid face! Thanks too Poppy - agreed shall wait for solid! BF continues 😏

Oh god yeah normal NHS people have no clue, I meant Quenby etc. Althoigh Shehata is also NHS, but he said he's not authorised to do the behaviour NK test at St Helier's - said they just don't do it 😪

Luna I would go with OPKs over any other sign, which would mean waiting for a solid smiley. I once had 8 flashing ones followed by a solid on the last evening! But usually it's fewer than that!

Reading and running (literally in a sec!) and will reply properly a bit later x

Oh Lun!! How exciting!!
I personally think it's best to wait for solid face, as if you start taking pred now you may not get preg til solid face, and get a bfn at Day 10 of pred (as it's too early) and stop popping pills even though you're preg!
Does that make sense??
When had things been going wrong for you before?

BF alert!!!

Yes... I'm finding out gender. Omg it feels so real, as the email with gender is in my inbox. Hubby doesn't know email is there but it's his Birthday today so he will know soon. We are keeping it to ourselves (if possible) and don't even wanna post gender in here in case my family come across this thread googling Mr S stuff!
Btw, I didn't know the NHS tested for nk cells? Unless you get referred to someone like Quenby, that's good! My NHS OB looked at me as if I were mad when she asked about them, I said I don't really know or care if it's real or not, as long as I'm having this baby! Lol

Poppy, I think I'm officially 2nd trimester in 4 days time at 13 weeks, can't wait!!! But had to give myself reality check last night as my APS/Hughes can be dangerous all the way through.
We told hubbys mum this week and she was beside herself. We plan on telling rest of hubby family when back from holiday next weekend (I'm currently in Devon)

Fingers crossed for your Addison's disease results being negative/good Red 🤞🏻

Xx

Welcome Red!

My turn to be ovu worrier Tee & everybody!

So I took the Clear Blue Digi Ovu test today and came up with a flashy face...

But according to Clue I'm not due to ovulate until Tuesday (day 15)... But according to Flo I'm due to ovulate tomorrow (day 13) 🤔

Shall I take Pred today, at flashy face?

Or

Shall I keep testing until I get solid face? Then bosh a Pred...

Or

Take a Pred on day 14 regardless of face?

Or

Have mental breakdown worrying about it?

Thank you so much for explaining all that Luna. I'm so sorry to hear that most of you have NK cells and I'm so pleased that Dr S has so much success. I'm hoping for all of you that it's a success for you too.

I am so pleased that it seems unlikely that I have it too. Just so relieved!

Over to the ladies for more details! Im awful at explaining!!

😂

Hi Red, just looked up Addisons - glad its most likely you don't have that Hun!!

Dr Shehata is from The Miscarriage Clinic in Epsom, Surrey. Most of us here are his [private] patients! He very expensive but his record in treating recurrent miscarriage is excellent!
www.miscarriageclinic.co.uk

Most of us here have an issue with our Natural Killer (NK) Cells:
www.google.co.uk/amp/www.motherandbaby.co.uk/amp/pregnancy-and-birth/pregnancy/pregnancy-health-conditions-explained/natural-killer-cells-what-are-they

• we are almos all on steroid treatment to dampen and calm our immune systems so our bodies stop killing the implanting embryo 🙌

You can get this looked into through NHS as well - although in my case they wouldn't have found what Dr S did, as my NK Cells are a normal amount just very aggressive - the NHS doesn't test for behaviour of Cells, just the amount

JustLa, that is such amazing news! So pleased for you!

Sorry for the late replies everyone, and thank you for all your kind words! I had to go for another test this morning at the hospital for Addison's disease but the nurse said she would call me if it was bad news to get me back in today. I've had no phone call so I'm hoping that means I'm in the clear for that.

Oh wow so much I don't know about! What is NK? And who is Dr S? Is she/he a fertility doctor?

JustLa, congratulations! So you're officially second trimester? Any plans to reveal to anyone yet? I'm so pleased for you...and the results sounds great too.

I hope Mr S stretched himself to sound congratulatory and encouraging, not brusque as usual?!

🎉 🎉🎉🎉🎉🎉🎉 just! Remind me, will you find out gender?