Immune /natural killer cell treatment when ttc or pregnant (aka the 16th pred thread!)

When I saw Dr s after the last mc he advised to not try during the wtf cycle and just let my body recover so not take any pred and then start again the cycle after (this cycle) if we felt ready.
I told him I was rubbish with opks, and I'd be damned if I'm shelling out more money on a clear blue one, and he said if my periods were fairly regular I could just estimate when I was likely to ovulate and start the pred then.

Gosh Snoopy that's so sad for your friends :( Yes, hope and gratitude are beautiful things :)

If this is your first Pred cycle why did you have a wtf cycle before?

It shouldn't mess up ovulation for your first cycle as you wouldn't start the pres until after ovulation. It may affect the following cycle though.

Are you using an ovulation kit? The clear blue digital kit seems to be working for me. Just make sure to follow the intructions about when to test (depends on your cycle length).

drttc don't apologise. You are perfectly entitled to feel down sometimes in these circumstances. Life is so cruel. Last night we had dinner with friends and in the two years they've been married her mum and his dad have both been diagnosed with terminal cancer. I can't imagine what they're both going through. But we do have hope. Sometimes I downplay so as to prepare for when the worst invariably happens but we are going to get there one day, all of us.

It is my first pred cycle. I took my eighth dose of steroids today. The past couple of days I have been so bloated and when I'm on my way home after work I get awful cramps in my legs (I'm not sure if this is just going from work boots to converse but never had it before steroids). And sorry for TMI but there is a lot of stuff going on down there. My wtf cycle was my standard 33 days so I presumed this one would be fine and didn't start taking the pred until cd21 in the hope it wouldn't mess up ovulation but now I don't know what to think. If it was late that means this cycle is completely wasted because we only dtd every other day in what we thought was our tww.

Snoopy - it was very upsetting! It may well be. Is this your first cycle using Pred?

Well I've just had my intralipids done! Should be ovulating today and so DTD this morning. I think this is us done for this cycle! Can't say I'm optimistic about pregnancy BUT talking to the nurse about her other patients & their struggles really helped me put things in perspective. It's so scary how with one swoop life can take everything from you... And it has NOT done that to us. It's so special that we get to come home to loved ones & hold each other every night. Motherhood is such a blessing and I would be so grateful to be able to have a child with my wonderful husband... I'm also grateful to have him to begin with! Sorry for the rant, I've really worked myself up and am super weepy!

Oh gosh hula, a 13 day cycle?! And drttc, it must have been a nightmare. Do you think that it could be causing my odd stuff down there I guess I only have to wait until Sunday/Monday to see the damage it has done.

Thanks for the info sw. I might look into that as a way of saving money. I'm dual nationality myself so it might be worth it. It's so hard when your future is uncertain to know what plans to make for the best. Night shifts are the pits aren't they. I used to really enjoy them but I am honestly a much more improved person on this schedule.

trying I feel that doubt everyday. I even said to DH yesterday please don't get your hopes up this cycle. If it's going to happen it'll happen next month, just in time for me to miscarry when we're on my special birthday holiday. I don't even believe I will conceive again if I'm honest. I just want my puppy (I know mentally it's a replacement baby), a new job and to make the most of my life.

Should here about the job I applied for soon, pretty sure I won't get it because of sickness but please send your good thoughts my way.

Hey Seeking! Thanks, I'll try to be more positive!

It made my cycle a mess. I had EWCM on cycle day 7, sore boobs for a few days after that (which is why I knew something was odd as I NEVER get that), couldn't detect ovulation, and then only had a 23 day cycle (has also never happened). I was acutely aware from the beginning of that cycle that my body was acting weird. I still ttc but then skipped Pred for that month (knew there was no point) and the next month everything ran like clockwork again and I got a BFP at the end.

Sorry you're worrying Drttc, but like the others have said, do t count yourself out yet.
Can I ask how the pred effected your cycle?? This will be my first cycle on it as it is supposed to have been taken. Did it shorten your luteal phase?

Drttc - sorry things aren t going to plan but i def wouldn t count yourself out for this month but I can sympathise about the worry of steriods messing with ur cycle, i m having a dilemma as to whether to risk trying them again. Not sure if the SO drugs can overide them messing with things as i had a 13 day cycle the month after i first tried them on a natural cycle.

Trying - ds is doing great thanks, hope you have a realxing break and dont miss your dh too much.

Snoopy - glad you re feeling better, work and routine can def be good distraction. Yes the scan is for follicles and when to time the trigger injection to release them. The aim is to have two follicle.

Swnanny - sorry this has been such a long haul for you. Are you having intralipids every month while trying naturally ? I asked dr s about that instead of steriods but he said because its expensive and only last 4 wks he didn t routinely do it.

Rosa - are u lurking ? How are you doing, is it ur 20 wk scan yet ? I hope all is well.

Hi determined, seeking and anyone else i ve missed.

Something i came across and wanted to share with u ladies so you d know about it for the future (and now Rosa) is a petition about preg women getting tested for strep b. Its been started by a women who heartbreakingly lost her baby at 9days old due to it. Its something a quarter of preg women can carry and pass to the baby at birth and can be prevented by testing in late preg and giving antibiotics in labour, however the nhs don t routinely do this.
Here's the link for more info and if you wanted to sign the petition:

www.change.org/p/nhs-provide-tests-for-group-b-strep-to-prevent-any-more-avoidable-deaths-of-newborn-babies

Thanks drttc ive read those threads a lot! I don't know why some days I stillpanic I'll be that odd one who won't get there. I suppose it's reassuring that we all feel that, and it's not just me tempting my own fate!
I hope ur feeling ok re intralipids, I'm sure u know ur cucle quite well and like snoopy said u may not ovulaye for a day or 2 still. Try chillax ! (Not possible i know)
Snoopy glad ur feeling a bit better about things....it takes time to heal and come out of the daze. It's obviously never exactly the same but I suppose that's wot life is! Things that happen change us...
Seeking-how was it? Hope ur ok....

Snoopy he is abroad. But within EU so good for prescriptions. Also a consultation and scan there only cost me £50. The same with my endocrinologist. So I always book loads of appointments when I go 'home'. It all adds up...
I know exactly how you feel about the job. I work a mix of days and nights. Didn't do any nights for quite a while and felt like a human being again.
Sadly my daytime job is going to finish in October so will have to start looking for a new one soon.
Just need to figure out first what we are doing about TTC first (if we decide for IVF I can't start new job till maybe january..) hope you will find better job soon. So you can relax a bit

sw is your gynaecologist in London?

Thanks drttc. I'm sorry it all seems to be going against plan at the moment. But you might not ovulate until at least 36hrs after a positive test so you might still be ok? I understand your fears, I'm worried the steroids might mess me up too, but it could all still be ok.

trying sorry you're feeling down, but you are too going to have a baby! And you're so strong, you can get through these dark days and remember 'everything will be ok in the end, if it's not ok it's not the end'.

hula hope the scan goes well. That's the one to check the follicles isn't it?

Well there's no more ewcm, it's gone kind of a lotion consistency, sorry this is all tmi. I have no idea what it is, cm, post dtd stuff, pre seed remnants? Interestingly a week before my first bfp I noted ewcm. Wish I had kept sort of record of this month but never mind. I don't want to get too paranoid about it all.

I can't explain how much better I feel physically. With a nice, normal routine. Even though I'm starting work at 0630am, I don't feel that real exhaustion deep down in my bones anymore. I can't believe I abused myself for so long! Now I just need a better job permanently, anyone know of any jobs going?!

Oh I am not with Dr s. I found a gynecologist who is happy to prescribe it. Some private Gp do as well. I just can't afford to pay any more as am having them once a month. Also I find it better on ovulation day as they tend to mess up my ovulation...
Oh Drttc that list brought a few tears into my eyes. I was following / was on all those threads from the first one. I remember those ladies.... Guess it just reminded me how long we've been trying...

We are replying so quickly I can't keep up!

Trying I already paid for my intralipids and have received the package at home :-/ I'm going to have to hope that I've got some EWCM hiding in there I guess. Last month I had SO much it was kinda gross... Figures!

SW, thanks! Does Dr S send your prescription to this place?

Few typos in there when u was copy and pasting- but they all went on to have babies!

Drttc sorry you are upset but no cycle is the same and who know this one might be THE one.
I don't know where you live but I have my intralipids at INS in london and they only charge £120. You need a prescription though. £300 per intralipid is loads of money...
Snoopy is it possible you are only ovulating now?

And Trying, I share your fear :( But so many women have been in our shoes and got there in the end!

Here are more successful people from this Pred thread! :

Old threads

Babies

Stogan - V high NKC - cycle#2, DC#1, Baby girl born Sunday 11/03/12 7lb13.5. Our First Pred Thread Baby!

Digitalgirl - High NKC - BFP cycle#2, Baby boy (DS2) born at 39+0 on Easter Monday, 9/04/12, 8 lbs 12 Our Second Pred Thread Baby!

BFP 3rd Trimester
Coconutfeet - V High NKC, Factor II gene mutation, underactive thyroid - BFP pre-pred, started at 6 weeks

Comedy - V High NKC - BFP cycle#2, DC#2 – 14/5/12

Iggi - High NKC & Hypothyroidism - BFP cycle#2, DC#2- 21/5/12

BrownieGecko - High NKC, Hypothyroidism, & Glucose Intolerant. BFP Clomid cycle#3, DC#1 33+2

Freelance - V High NKC TTC#1 Hydroxychloroquine, Pred, Intralipids, 400 Cyclogest, Thyroid/hashimotos. MC 1st Pred cycle. 2 Pred babies!

Cheerfulcharlie - V High NKC, MTHFR, DC#2/ (metformin, intralipids, no pred).

batteryhen - High NKC, factor v leiden. DC#1 BFP cycle 3. 22+4
coleyoz - V High NKC. DC#2,

Oh sorry drttc. hmmmm can u postpone them till next month if u don't feel like this is ur month? If that make sense?
I found ecwm is sometimes a bit unreliable and I would get it a few days before the day of a surge or even day after postive stick. I fink sometimes it's there before but just not obvious....im sure having intralipids one or 2 days here or there won't mayyer? As they will be working by implantation time?
It's such a confusing scenario all this complex ttc!

Glad dc's op went well Hula! Hope you're not too shaken.

Hey Snoopy! Good luck with your cycle... Hopefully it all becomes clear soon!

Trying, hope you're little break is rejuvenating & leaves you feeling more positive :)

Well I'm so disappointed! I got a positive ovulation test today... Usually that would be good except for 1. I have no EWCM (ARGH!!!) and 2. My intralipids are tomorrow... So same day of ovulation instead of before. Basically the plan has gone tits up. I have preseed so I'll use that in hope that it will replace EWCM... But not feeling hopeful. Even worse, I'm worried that after taking steroids this cycle it will mess up my cycle next month (just like it did the last time I took them).

So that'll be lots of time, £600 on intralipids, and anxiety for 2 cycles that are already following the exact pattern of my previous unsuccessful post miscarriage cycles (break month okay, first ttc month no EWCM, 2nd ttc month really weird 23 day cycle due to steroids). I know I should be more positive but I can't help notice similarities :( We really can't afford intralipids every month & this cycle was our one true shot without the steroids interfering.

Hey guys
Hula how is dc
Yep snoopy can be hard to tell between ecwm and DTD! But u can get some before AF too like huka said I noted it some months.

Determined im off tmrw I hope I don't get preg as dH not coming haha! He's working long hours and his friend is coming to visit and I had leave so was perfect for me to visit a friend living out there for 3 nights. I feel bad leaving him with the miscarriahe being so recent but he won't get home till 9ish and its prob nicer for him to be with his mate without me cramping their style! Plus he really wanted me to go...did make a lot of a food for him yest and buy him some tasty puddings so I feel less bad about it! I think sun and a break from UK will do me some good. I do feel like I'm a bit up and down.

I'm terrfied this won't ever work out for me, I can't imagine not having a family :( it really scares me.....

Seeking hope appt goes to plan and ur ok x

Oh I've also just read it could be leftovers from DTD (gross ). It's just too confusing

Oh well, I guess af should arrive this weekend then

Snoopy i ve had similar before and when i looked into it i found out that you have a slight increase in oestrogen as the progesterone drops just before af so can cause some inc in cm so maybe its that ?

hula so pleased ds's operation went well, maybe not having the added stress will help this cycle?

Good to see lots of holidays being planned, I know I can't wait for mine in September. And seeking I'm so jealous you'll have your puppy soon, looks like we'll have to wait until November for ours!

I don't know what my body is doing, I'm on cd 29/30 (don't know how the two apps got in to different days ) and seem to have a lot ewcm. I haven't been checking at all, or temping or opking, because frankly I can't be bothered and what will be will be, but this was very noticeable.