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Conception

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Immune /natural killer cell treatment when ttc or pregnant (aka the 16th pred thread!)

992 replies

sunnyday01 · 05/06/2015 19:22

This is a thread for those diagnosed with high or very high natural killer cells and trying to concieve or are pregnant and taking steroids/intralipids etc

Newcomers very welcome

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Snoopysimaginaryfriend · 11/06/2015 19:47

seeking I know that the grief and pain is still very raw but in my more optimistic moments I try to say to myself that I got pregnant this third time and didn't start my medication until after bfp so maybe it didn't have a chance to work as well and my NK cells were still too high. I think you were in a similar position. I know you won't have had time to fully take in everything but that has been my tiny glimmer of hope for the future.

Rosa27 · 11/06/2015 19:22

Trying .. Also sorry for your added challenge and stress. But confident you're the most informed of the lot of us and feel sure you'll get there. Xx

Rosa27 · 11/06/2015 19:14

Seeking - so, so sorry. I hadn't seen the last page when I wrote my last one .. Absolutely gutted for you :(
I'm so sad you will be sad - I hope you can get through this with lots of love and support. Xxx

Rosa27 · 11/06/2015 19:03

Seeking - I was in your boat with cyclogest. I upped to twice when spotted though at 5 weeks and got cyclogest on nhs. I get via Boots and just told them and my GP reception I needed to 16 weeks and they sorted it. I think I picked up 8 boxes last week and after this week only have 2 weeks left so should have spare if you want me to post? Should have said they gave me enough for 2 a day up to 16 weeks but I switched back to 1 a day at 12 weeks.
Sunny - try not to worry as others say. You might be advised to get GP to test for infection but I've had 'tinted discharge' or watery with white flecks (sorry all tmi) and each time I google and stress but think (hope) am ok.
Trying - great news that big hurdle is over, well done! Enjoy the celebratory cuisine :)
Hi everyone else x

Snoopysimaginaryfriend · 11/06/2015 19:01

seeking I'm so sorry. I don't know what to say because nothing will make it better. I'm so heartbroken for you. I hope you have support around you and I will be thinking of you x

Hello sasha, you're welcome here anytime. I don't know if the ivig is available on the nhs. Did the lister give you a copy of your results? If not I would definitely bring a copy of them to your appointment with Dr s . Sorry I can't be more help.

Hula2 · 11/06/2015 18:59

Oh god seeking, so so sorry. There s no words to ease the awful pain you must be feeling. I m so sorry.

Hula2 · 11/06/2015 18:57

Trying - so sorry you got this news. Life is a b*tch and its just not fair you ve got this to contend with too but please don t give up hope. You ve got 10 eggs which is great and enough sperm to fertilise them so hopefully you ll get some great embryos and maybe even some to freeze. I know one couple who now have 2 kids 9mns apart and all from their first ivf round so it can happen. Good idea to ask not to deal with the results till after the tww so you can try to just focus your positive thoughts on those little embies. Hugs

Tryingno1 · 11/06/2015 18:55

Oh Seeking. I'm so so so sorry. Flowers
After a good scan, a loss is such a huge shock. I've been there before.
I'm sorry, thinking of u and ur DH
Xxxxxx

Seekingmiracles · 11/06/2015 18:53

Bad news here afraid. Baby died at 8+6. I'm absolutely heartbroken and shocked. I felt so confident after the last scan.

SashaKerr · 11/06/2015 17:12

This reply has been deleted

Message withdrawn at poster's request.

Tryingno1 · 11/06/2015 16:13

Seeking lots of happy positive vibes for ur scan later!

Tryingno1 · 11/06/2015 15:40

Thanks guys. I almost want to ring my ivf place up and tell them not to tell me my DH results as I only want to think postive (after today!). If it's a y deletion it means all our sons would have it :(

They Bascially said u need one sperm per egg with ISCI so it didn't matter. And that the whole pt of isci was that it's for people with little sperm. The fact it has taken such a huge nose dive scares me...it's going down so quickly. What is by next week there are zero???
the talk of freezing sperm and all that has terrified the hell out of me. To be honest if we hadn't have questioned why his sperm had dropped again and how we got preg after trying for One month twice he wouldn't have had this chat with us. It's always perplexed us. Makes u realise how much u have to question everything.

I don't even know wot to think anymore. I'll pull myself together by tmre ( I hope).

Seekingmiracles · 11/06/2015 15:31

Oh Trying I am sorry you been dealt another cruel blow but dont start thinking your journey is over. It's not. ICSI doesn't need millions of sperm, just a few good ones! You may end up with good quality embies. And you only need one of those to work. You e caught this early enough that you can get freezing if need be. Do not give up Hun. Your journey is very far from over!! You need to keep positive, calm and relaxed over the next few days and just keep thinking of your eggs and dh's sperm coming together and creating your perfect little baby. Positive visualisation. I'm sending you lots of positivity. Try to erase this recent news from your mind for the time being. At least until you know how the next few days go. Big hugs Hun

Snoopysimaginaryfriend · 11/06/2015 15:12

Oh trying I'm so sorry. I was just about to say well done getting ten little eggs and then I saw your most recent post. I know it feels like the bad news keeps coming but your doctor sounds like he's on top of the situation and he's right, you only need ten. At least you're finding out now so if you need to start freezing you can and I am sure you will be a mum. You've helped me through the dark days so I'm sending some of those positive thoughts back to you x

seeking I know it's cheeky but you could always tell the nhs you lost some of your cyclogest (left in hotel room etc). I've done that when I'm about to run out of thyroxine before but now my chemist always gives me some early Grin I demand to see puppy pictures as well! We've decided on a border terrier (when I say we that's dh, my mum who will help with dog sitting, and my brother who wants to be a dog uncle again) We won't be getting one until late September though because we're going away for two weeks for my birthday and it wouldn't be fair on the little puppy.

sunny try not to worry, I know easier said than done, but you've had good scans and I'm sure it will be ok.

rosa and hula I think I'm going to give acupuncture I try. I've found someone with good reviews in my area.

Tryingno1 · 11/06/2015 14:53

Thanks guys
So bad news. Does it ever stop? My DH sperm has nose dived AGAIN. It was 4.8 million 2 months ago and today more like 0.3. He doesn't drink or smoke eats healthy and has normal bmi.
He's had some bloods done today including hormones and for and a y chromosome deletion. But it's making sense why we had 3 quick pregnancies and then started struggling and again count has taken a dive. Sup the y deletion does this...it starts tailing off and then u are left with no sperm.

There were more than enough soerm for the Isci I was told. We only need 10! And they didn't want a second sample from him so the embryologist was fine about that

If it's hormonal it can be tx with meds. If it's chromosomal we need to start freezing sperm as his count can continue to drop to nothing.

I'm devastated. I thought I could do 10 ivf goes and one would work and not miscarry. And now we might only have a few chances as long as he has some Sperm. I feel like I need to imagine my life with no children now and prepare myself for it.

Sorry, this has been a happy thread this last few weeks.

Not feeling hopeful this cycle will work now, and not feeling hopeful this will ever work out for us

Xx

Seekingmiracles · 11/06/2015 14:28

Oh... I'm always kept waiting with DrS Sunny, not that long but he does seem to run late mostly. Only had one appointment when he's been on time (early actually!)

Seekingmiracles · 11/06/2015 14:27

10 is good Trying! Glad it went well!! You totally deserve some tasty treats!

This weather is amazing! Had a nice long walk this morning with my mums dog, was beautiful! Can't wait to have my own dog! We've just arranged to go pick our puppy on 28th.I can't wait! Then we'll bring it home at the end of July.Grin

sunnyday01 · 11/06/2015 13:51

great news trying, 10 sounds like a good number so hopefully there will be some good'uns! When is the transfer back in? Are you having icsi or normal ivf?

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Tryingno1 · 11/06/2015 11:19

Re ur bp it will be the pred and u were prob anxious! My first bp at the ivf place was mega High but every visit after when ive been calmer and used to it have been fine so emotions def raise it. A few home measurements and when ur off the pred things will settle!

Tryingno1 · 11/06/2015 11:10

Hey guys.

All went well. Was straightforward and I was totally knocked out and don't rem a thing. I'm just having some period cramps now but it's totally tolerable. Much more straight fwd that I thought.

They got ten eggs which is fair/good. I was hoping for a few more but it's more imp they r good quality and my consultant seemed happy. Just hope they r healthy and mature! Going to spend day lying in sun and Gonna eat lots of tasty food as treats today!

Seeking I would just tell mr s u are taking 2-he advises 2 when people spot anyways and u did spot. He won't mind he knows we are anxious ladies and prefer to throw everything at it
Sunny don't worry re ur mucus u have had a good scan and so that should reassure u. In pregnancy cervical mucus thickens and u get more so u will just be gettingn a normal response.

X

sunnyday01 · 11/06/2015 10:37

i'd just ask mr s for more - if he asks why you can tell him, if he doesn't you don't have to say anything!!

He kept me waiting for nearly half an hour yesterday which was annoying, the patient before me went in a 3.20 and came out a 3.35, my appointment was at 3.30, but didn't get called in until 3.55!!

Have just emailed Luoise about my blood pressure monitor so asked about the discharge, but hopefully i'll be like you seeking and it'll be nothing to worry about.

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Seekingmiracles · 11/06/2015 10:33

I have had all my cyclogest from the NHS but they've said I only benefit until 12 weeks and gave me enough for 2 daily until then, which I've been doing. But drS said 1 daily until 16weeks. I doubt NHS will give me more considering I've had what they suggested.
WOuld have been funny to bump into each other Sunny Smile
I've also had funny coloured mucus on/off and DrS said not to worry too much as pregnancy seems to be developing well regardless. It's still worrying though

sunnyday01 · 11/06/2015 09:41

Finally catching up!! thanks for all your wishes - lets hope it all continues to progress well! However over the last couple of days i have had some odd coloured mucas when wiping (sorry if TMI), the rest of the toilet paper is clean but the actual mucas is not clear - can't decide if its greeny/yellow or beigy/brown - trying to not be too concerned but any thoughts?

Rosa - can't believe your NHS consultant said those things to you, how rude. I don't think it is any of her business really. I've decided I'm not going to tell the nhs what i'm doing. My gp has a letter from Mr S (actually my gp has been very good and given me the pred and progesterone on prescription :)) but unless they ask I won't be saying!

I started asprin once i got bfp - but that was just coincidence really as i was off all my drugs due to DH's issue. I haven't done much research in to it so have no real thoughts either way. I'd ask your ivf consultant and let him guide what you do.

Sorry you are stuggling snoopy, we have all been there. You just have to do what is best for you x Maybe counselling would help you to express all your feelings and talk it through with someone external to the situation? Look after yourself.

Seeking - my scan is at 11.30! Probably miss each other, would have been funny if we were next to each other! How many weeks are you now? Good luck for today - i'm already worrying about the next one! As for the cylogest - no idea - i'm sure you can get some from nhs if they are telling you 2 a day?

Hope everyone else is ok - drttc, hula....hope...

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Drttc · 11/06/2015 09:36

Awesome news Sunny!!!

Good luck today Trying, I'm sure everything will go smoothly. Looking forward to hearing about it!

Seeking, personally, I'd be tempted to take 2 daily... Or maybe alternate haha? Like one day 2, one day 1? Point being I'd want to take more to be 'safe'. Then eventually just admit it to Dr S. Though you'd think you could get cyclogest from NHS if they've told you to take 2 a day?

Seekingmiracles · 11/06/2015 08:39

Advice please ladies.... So DrS said cyclogest 1 x daily, NHS consultant said cyclogest 2x daily. Started on one per day until I had the brown spotting, since then I've been taking it twice daily as was worried the spotting could be progesterone related. Anyway I have enough to get me to 12 weeks as per NHS instruction but DrS said to take it until 16weeks. Do I admit I've been taking more than he recommended or just say i've run out and then switch to 1x daily until 16 weeks (not admitting I went with NHS instruction over his!).

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