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Immune /natural killer cell treatment when ttc or pregnant (aka the 16th pred thread!)

992 replies

sunnyday01 · 05/06/2015 19:22

This is a thread for those diagnosed with high or very high natural killer cells and trying to concieve or are pregnant and taking steroids/intralipids etc

Newcomers very welcome

OP posts:
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5
Determined123 · 09/07/2015 10:00

Ahhh I want to give you both a big fat virtual hug! It sounds like the two of you are making each other stronger through this and that's so special!

Yeah, test was done yesterday...got to be honest that last few days i have had zero sleep and mega stress with work so my NK cells were probably mental!

I really tried my best to tell myself i didn't have any (NK cells) and the drugs were working this time but we will see (mind over matter eh). I get my results next week so that's it, nothing more to be done but face the music of whatever we need to do on this TTC journey...(if we decide to do it of course).

I really really really advise the break...i am in such a better place mentally i am happier and positive and actually look forward to things and enjoy them when i do them. I was so depressed at the beginning on the year and i think so was (or it was deffo impacting) DH. I am fitter, stronger, I smile, I laugh...(i don't cry all the time). I am like a different person and i feel ready to deal with whatever life throws at me again...but with a lot more wisdom and reflection! Sounds a bit deep but it is amazing what a few months and a bit of acceptance and dealing with it can do. I really think it will do you the world of good to get your mind and your body primed. Its been through a lot!

I really hope today is a quick and easy as it possibly can be xxx

Tryingno1 · 09/07/2015 08:55

Thanks determined. I do feel so lucky to have him. He's been kind supportive loving and caring. And also practical and descisive. He hasn't been a guy about his sperm count like I would have thought and just supported me through the ivf and didn't bring it up. I've started wondering if maybe the greater beings that exist think I should be happy with just him and shouldn't ask for more as im already lucky to have him. But he says life doesn't work like that! It's not one or the other!
How r u lovely? Are u waiting for ur retest, going to take a leaf about ur book and break from TtC after this weekend and just take a step back from thinking of it all. I need to loose this pred weight and enjoy life and start thinking again in a few months.
Ps of I end up at argc they use ivig Confused

Determined123 · 09/07/2015 08:22

Thinking of you trying!! Flowers sounds like you are doing the right thing and getting appointments and trips booked to keep moving forward and keep busy. You are being so incredibly strong! I've no idea why some of us are placed on this journey...maybe we are the strong ones but I really do believe we will all get there someway or how! It just takes a lot of perseverance and bravery!!! You DH sounds like an amazing man...I hope you two can take comfort in how special you two are together whilst going through such a crappy time! Love and hugs and hope today goes ok xxx

Tryingno1 · 09/07/2015 07:25

My Dh is convinced it's his sperm causing the issue now. Dna fragmention, Ros tests on sperm and sperm anueploidy seems to be the sort of things we need to look into. How did things get so complex?! I'm sure it's not meant to be this hard? And am I looking for answers that are not there? Is it just bad luck and I'll be fine next time with no Tx?! Not sure I want to take risk to be fair!

Tryingno1 · 09/07/2015 07:22

Hi hula. Thanks sw.
God it's awful when u wake up and rem isn't it. I thought this one might work as it was my first on the drugs.

Like u DRtCC I seem to be loosing them early. I reckon I prob only made it to 4.5 weeks , same as my last one. For some reason my second made it to 9 though? No pattern...and the first 6. Either way the time is getting less not sure if this bodes well?

Yes I'm going to stress how imp the karotype is, d and c this afternoon. I can't believe 4 miscarriages aged 28-31 can all be chromosomal. And it's annoying not knowing and wondering. I wish I had done PGd this time, I'm annoyed I didn't push for it.

Argc is like 15 grand with full immunes :( . wont get it on nhs I live up North and just had my one nhs cycle. (Which cost 4 grand !???)

I feel like maybe it's too drastic and I really dont fancy uprooting my life to london. But with DH sperm while i its dissapering we have to act while he's still making some fresh stuff. If I spend another year trying 2 more cycles here and then in a years time he makes zero fresh sperm? The frozen stuff we are saving up doesn't always defrost well, although I'm grateful we are saving it and realised at this stage what's going on (weekly wanks at clinic, poor Dh).

I think our urology appt will be the most imp, the chap is kinda the shehata of the low sperm world! I suppose he will be best in guiding us how quickly we need to act. He may have some tx that may improve things etc

If there was no sperm issue I would just use up my 3 blastocsysts here first.....
But on the other hand it means uprooting my life and taking time off work as they do daily bloods during stimming and when u get pregnant....there's a lady on the RM thread who has had a natural preg and gone to them for their monitoring and drugs maybe I'll drop her a line... I don't really fancy turning my life upside down. But maybe I need to?

Xxx

swlondonnanny · 09/07/2015 06:49

Trying I am so sorry.
Thinking of you today

Hula2 · 08/07/2015 23:56

Aw trying, good you ve made a plan.
Sounds sensible to have the dnc rather than wait. Will you have testing to see if it was a chromosal issue ? At least with ivf you ve got the PGD option next time. Will you be able to get any bits of your argc cycle on the nhs ? (I m guessing they are particularily expensive). I hope tomorrow goes as smoothly as possible, will be thinking of you.

Tryingno1 · 08/07/2015 23:01

Yes wonderful DH's. Feel so bad he's so kind and lovely and I wish I could give him a little one :(

Got mine booked tmrw, I never miscarry naturally and ive had failed natural and medical management before and the whole process gets dragged out. Absolutely can't be bothered with that this time so just want it over.

I've joined the gym and ive registered with the argc today. I've booked flights to see a friend in Spain for a weeken when DH was at a course. I'm going to get fit and pray and hope its next time or the time after. I'll prob go into it with PGD incase it is chromosomal although I doubt it.

Hope everyone else doing ok? Bit shit on the thread recently after some wonderful news. Let's
Hope it picks up xxx

Drttc · 08/07/2015 22:51

So so sorry Trying. I can completely relate as you know... Have had an almost identical 4th mc just a few weeks ago :( It sounds it'll happen naturally though and you won't need a d&c.... Hope you have comforting cuddles from your hubby & that you can both look ahead with hope in your hearts xx

Rosa27 · 08/07/2015 22:21

Yes most of us are blessed I think more than others with Super-DHs. It's thee most important thing. I really wish, hope and pray we are all blessed in every way too though.
Take care xx

Tryingno1 · 08/07/2015 19:37

Thanks for ur words. Life is shit, what can u do. Ur right, let's hope it's a numbers game just when is it my turn? And all of u other lovely ladies.

At least I have my wonderful DH even If we have about ten sperm left and I'm not sure on our chances of a bfp are let alone a miscarriage again.

Booked appt at argc in London. Think that's my next port of call.

Wine and chocolate and my lovely DH for next few days
Xxx

Snoopysimaginaryfriend · 08/07/2015 19:32

Oh trying, so so sad for you and your DH. Can't imagine how you're feeling. We're here whenever you need support. Please take care of yourself x

Rosa27 · 08/07/2015 18:33

Big hug even ! Xx

Rosa27 · 08/07/2015 18:33

Trying - so sorry, gutted for you. Really thought this was it. Don't give up though.. Everything is lined up for success now, it's just a lottery with which will make it but fingers crossed this year is a lucky year overall. Sorry you're going through this now though - it's just not fair- especially after all you've been through. Bug hug xx

Determined123 · 08/07/2015 18:01

Am so sorry trying!! Like hula said I never understand why life does this it's so cruel! Thinking of you and DH! Hugs xxx

Hula2 · 08/07/2015 17:55

Oh Trying i m so so sorry. That s so unfair, life is just so shitty sometimes. I really hope you are as ok as you can be. Sending u the biggest cyber hug.

sunnyday01 · 08/07/2015 17:25

Oh trying, I'm so sorry that they have gone down. Thinking of you and look after yourself xx

OP posts:
Tryingno1 · 08/07/2015 16:42

Levels down to 391. :(
Hoping if I stop all the meds it may happen naturally? Ow I'll book a d and c tmrw.
Sigh. Thanks for thinking of me
Xxx

Drttc · 08/07/2015 15:39

Yes, sending you a big hug trying xx

Hula2 · 08/07/2015 10:33

Trying - i hope you re ok. Thinking of you.

MorganLeFey · 07/07/2015 21:17

Trying So sorry to hear what you're going through - as people have said it's still not definitely over even if you're feeling realistically pessimistic.
If it is then I think the keep going with fresh sperm is a great plan - we obsess over our eggs/lining then all it can take is 1 sperm! My two baby bombs from close friends since I started having miscarriages had both been trying for over a year & a half to conceive with men with known sperm issues - but then they did & that one got them their babies!
How many D&Cs have you had now? I've had 2MMC (+ 1 natural) & reframed it in my mind as rather than my body failing to do & MC naturally as the foetus/baby & my body wanting to stay as close as possible for as long as possible and not let go - which although really sad gave me comfort in some strange way.

Tryingno1 · 07/07/2015 20:32

Why do I never bleed. How many d and c can one person have in their life :(

Tryingno1 · 07/07/2015 20:29

I have seen that hula. Find it v hard to believe. Thanks for trying to be hopeful for me. Online forums suggest 10000s by now. Anyways yes will know tmrw.
Sigh.
When r u testing? We due more good news on here, I hope it's u next x

Hula2 · 07/07/2015 20:20

I hope thats was clear that is was a range from 18 to 7000 (not 187000).

Hula2 · 07/07/2015 20:16

Trying don t apologise, thats what we re here for. From googling charts wk 5 seems to have the highest variability (some said at normal level was 18-7000 !) so this really is just a baseline. Try not to think too far ahead, just focus on trying to stay calm and get through the next 24 hours. I m hoping with all i ve got you get doubled numbers tomorrow.

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