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Conception

When's the best time to get pregnant? Use our interactive ovulation calculator to work out when you're most fertile and most likely to conceive.

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Original poster

RESPONSE trial thread

984 replies

Marchgirl · 04/05/2015 19:50

For anyone who had joined or is thinking of joining the RESPONSE medical trial for recurrent miscarriage

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Original poster
Marchgirl · 30/05/2015 19:31

I was planning to wait until cd14 to opk test claire, but ended up testing yesterday and today (cd11) as I've had fertile cm for 3 days. Still negative opk but it's very confusing. Having said that, the last 2 months I've had a bit of fertile cm a couple of times around this time, but not as much or for as long. Probably still be cd17 after all that! Progesterone doesn't start til 7dpo so got a while before that.

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Original poster
Marchgirl · 30/05/2015 19:26

Glad your people are looking after you girlie Flowers. Is the bruise from erpc?

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girliesaints · 30/05/2015 19:07

I'm fine ladies. Been looked after by DH & dd, although they have been out for most of the day to give me some peace.

Starting to get a nice bruise on my tummy and apart from feeling a bit sore I'm fine.

In terms of testing I was dpo13 last time before I got a definite line, although I had a shadow two days before but I assumed it wasn't a positive but in hindsight properly was.

Kazz2112 · 30/05/2015 18:59

That sounds good then. Prior to getting the smiley we dtd at least once a day for the 5 days prior to it! It sounds ridiculous but with me being off work this week after I've been able to lounge about in bed a bit. Hopefully giving them some assistance with gravity! Fingers crossed.

I've no symptoms atm other than being extremely tired but that may well just be the miles and miles walked around Barcelona. I also got hone from our trip and all I can smell is the bin but DH claims he can't smell it. Could just be an excuse because he wants to watch football / cricket and not be doing chores!

I'm due to get my results back from my 3rd lupus screening on monday So will have a more clear idea of possible Hughes / antiphospholipid syndrome then. Going to be a big week next week for results.

clairemorgan81 · 30/05/2015 18:52

thinking of you girlie.hope your recovery is going okay.

good luck with testing kazz.Smile hope you have a bfp this month.

I'm on cd13 so doing ov tests at the minute. expect my smiley anywhere from tomorrow to CD17.

March what's your plan this month? I'm not clued up on progesterone and when you start etc x

Original poster
Marchgirl · 30/05/2015 18:17

Snap advice indie!

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Original poster
Marchgirl · 30/05/2015 18:16

Oh, and I've never had a bfp before 11 dpo, and that was on a frer, so don't be surprised if you don't get anything before 12 or 13 on the trial tests (just don't want you to get disheartened).

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Indiedog · 30/05/2015 18:14

Kazz, I got my BFP 10days Post ovulation. Got my smiley 15th March, got my BFP 25th March, very faint, I took the test apart as I thought I could see a line. Then I did another that Eve after work, and it was darker.
So I think it does vary greatly.
Don't get disheartened, as we are all different.

Original poster
Marchgirl · 30/05/2015 18:13

I wouldn't worry about the day after that kaz, it's the day of ov and the day before that are the most important ones, followed by the few days before that. I think they say the days after ov are very unlikely to make any difference as the egg can't survive for long if it's not fertilised, so i think you'll be covered with the others. Fingers crossed for you Smile

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Choccywoccydodah · 30/05/2015 18:09

Good luck testing kazz!! Everything crossed for some positive news.
I always got my bfps early (5/6/7dpo) so I'm not a good example to answer lol! This one was 6dpo from my dating scan date, 5dpo from when I thought I ovulated, 3 days past cb smiley (which I always thought was wrong!) x

Kazz2112 · 30/05/2015 17:58

Hope you are feeling as ok as can be and recovering well Girlie.

I think that's so unfair that you were only allowed on round of toast!!! :( Very mean!

I start with the pg tests tomorrow morning so hoping for some positive news to share as requested! I'm feeling very apprehensive about it at the moment. How early did everyone else get there bfps? I'm currently cd22, will be cd23 tomorrow (obviously) and got my smiley on cd16.

I'm really worried we messed up with the ttc. Went for it x2 on the smiley day and x2 the day after (where i had a smiley in the morning but not evening) and then once the day after the smileys but then DH was too hungover the following day! :( Ill be so gutted if i dont get a bfp. I suspect my next smiley is going to fall when im away on my sisters hen do and DH is off to Germany with a mate. Short of a pot and a turkey baster next cycle would be unlikely!

Choccywoccydodah · 30/05/2015 17:07

How've you been today girlie? Xx

girliesaints · 29/05/2015 20:40

Bless you lovely ladies!

Back home now and installed on the sofa and have been looked after by doc mcstuffin aka dd!

NHS toast was soo amazing I asked if I could have another round and got refused- how rude!

Enough of me. No pressure ladies but need happy news over next few weeks in terms of scans & bfp! ??

philippa88 · 29/05/2015 20:24

So sorry girlie, honestly my heart goes out to you :( I know it's hard but you have to keep fighting, one day this will work and you'll finally get that rainbow baby. Hugs xxx

SushieS · 29/05/2015 19:34

Really sad to hear that girlie...thinking of you and sending hugs. Hope there's some consolation in the fact that you've potentially helped millions of women in the future...without everyone being involved taking a leap of faith and trialling new drugs advancements in MC treatment wouldn't be possible. Really hope you get extra special treatment and investigation and next time it's a different outcome. I know from your words, and others on the thread, it's made me want to be part of it all.xxx

Kazz2112 · 29/05/2015 18:37

What is it with NHS toast??? Its amazing. My DH is nodding in agreement.

Get lots of rest now girlie. Glad to hear it sounds like you're being looked After. You will get your happy ending. Our roads are all just a little more windy than some.xxc

Joy2713 · 29/05/2015 17:09

Glad it went ok as could be and hopefully you'll be on your way home soon! Xxx

Choccywoccydodah · 29/05/2015 16:12

Girlie glad all went as well as could be. Nhs toast is fab (the only food they seem to get right!!)
I'm glad you now get fast tracked to the next stage, that's at least something you haven't got to worry about.

I was told they were stopping recruiting in June a few weeks ago too, but those ladies only had 3 months to catch as they want to bring the trial to a close, talk about pressure!

girliesaints · 29/05/2015 15:43

NHS toast is the best.

Have to see A & J in a month's time to follow up after finishing the drugs, which will be great.

There are some other trials ongoing that the miscarriage research nurse is going to run through but sadly not with J & A.

Size, meant to say loved your saying. I firmly believe this is part of my journey to get to dream.

Indiedog · 29/05/2015 15:41

Crossed threads with you girlie.

Glad your be in the system now. I can't beleive how long they left me after my fourth MC.

Make sure you stay on their case.
There will be something out there for you, and it will happen.
Xx

Indiedog · 29/05/2015 15:40

Hello girlie. NHS toast, I hope it's good xxx

Glad your ok.
Do you get to see A or J again at some point. Maybe they know or have connections with any other trials that may be in the future.
Too early to think about maybe, but something to keep in mind perhaps.

I hope your home soon, can't beat home comforts.
Of course stick around, we want to know your ok too don't forget xx

girliesaints · 29/05/2015 15:36

Thanks Indie, I'm seeing the recurrent miscarriage research nurse next week to discuss options. Apparently another bonus of the trial means I don't have to go through the normal wait times and she'll be able to fast track appointments for me.

Going to be sad to leave A & J. A even emailed me today to let me know she was thinking of me and she's on holiday. Bless.

girliesaints · 29/05/2015 15:34

Thanks ladies. Back from surgery and currently munching on toast.

I forgot to say earlier apparently they are stopping recruiting for the trial in June as the uptake as been so popular. I certainly feel honoured to have taken part.

If it's ok, I would like to stick around on the thread to see what happens with everyone.

Indiedog · 29/05/2015 15:32

Oh girlie, so sorry to see its not worked out this time. I am glad you are being looked after, and things are moving along. I guess that is the only consolation of being in the trial, is the extra care.
I wish you a speedy recovery, and that you and your partner etc are ok.
I had been thinking of you all the way home too.
I hope once you've recovered, physically and mentally (not that we forget) that the hospital can give you some more options, or tests and support.

We are all here to offer support, to let each other let off steam, and we are all here for you. ThanksThanks

Big hugs xxx

Kazz2112 · 29/05/2015 14:31

That's a lovely saying Size and so true.xxxx

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