Immune / natural killer cell treatment when ttc or pregnant (aka the 15th pred thread)

Hey guys hope u all had good weekends.
Rosa and seeking hope u had a little less of a panic filled weekend.
Determined have u been able to decide in ur plan yet?
Hula when is ur retest?
Drttc hope ur staying postive!
Snoopy, don't worry about ur NK levels they are typical of those who have raised levels and the meds will hopefully bring them down. Are u starting to TTC now? Take as much time off from work u need, it's a tough emotional and physical process to go through. U need lots of tlc.

I started my injections! So far no issues, got my first scan and my intralipids on Friday. Egg collection week after sometime! Quite exciting and I'm still ina calm relaxed state which is good.

Snoopy where you have 260, I have 280... It's meant to be below 200. I was classed as high and you're lower than me so don't think on this one you're beyond the realms of help.. Def seen worse numbers - and also know people with very high who had babies.
I understand on the talking thing.. For me the last thing I wanted to do in precious recovery time was going back to talking about the darkest most painful memories. I do know though that the process if articulating your feelings really helps you process them and move on. I think this can also work with writing like on these forums. Whatever works x

Yeah I know you're right rosa. I think I'm firmly mired in the 'depression' stage of grief. I should have called occupational health today but I couldn't face talking about something so intimate with a faceless stranger over the phone.

DH's working a night shift tonight and one if the girls at work has just come back from a holiday and texted me she hopes I feel better soon because everyone thinks I'm just sick. I don't know what to tell her. She's the only one who knows about the two previous mc but I don't know if I want to tell her I've joined the club no one wants to be a part of.

I have a question for you knowledgable ladies. On my results it says - total NK cell absolute count: 260.7. How do I convert that into the numbers I've seen you talk about or is that your total NK cd69 absolute count - in which case mine is 0.56. Is that really bad?

Ps snoopy I had that on my elbows but pred made it go away. It can't hurt to get your GP's advice in the meantime before you see Mr S.. You could always try a different one and you don't need up take the advice .. Just sometime interesting to get opinions and info ..

Welcome Catmum- and congrats .. Great you've joined on a positive :)
Seeking - woohoo! My phone died (thought was broken) yesterday and just managed to charge .. been thinking of you.. SO glad all good!
Trying - you too.. It's all go and I've a good feeling about this. It's your time. As you say though, worst case you take a breath and go again. But think you should feel lucky.
Drttc - I've found it really tough too but all I can say is for no particular reason some days feel better than others so hang in there and focus in things you can control like good diet, regularly keeping your fluids up and doing anything that makes you feel relaxed. Especially if it also distracts you a bit as time will then drag a bit less.
Snoopy- I hope you feel better today. It's very hard when you plan things out and imagine not only dates relating to your babies but your life. I've made so many decisions around what I hoped would happen. I'm finding myself talking a lot more like 'if all keeps going well' this time but know it would be no less devastating if it doesn't. It's just human nature to dream and hope and so keep doing that because I'm sure you will get lucky soon (this is the lucky thread and a lucky year) and in the meantime we're all here for you xx

trying don't apologise. We're all excited for you, starting your journey. You're going to be another success story!

Great news seeking

Speaking of success stories a lady my mum knows was treated for NK cells at the Lister and she now has two children!

I'm starting to get a bit worried and I'm going into a Google meltdown. Everytime I get pregnant I develop this patch of red skin, like a rash on my face. This time it disappeared for the two weeks I took the pred. Just before this last miscarriage I got really bad pains in my knees and the patch of bad skin started coming back. Now it's spread to the top of my right arm so I showed my mum and she confirmed its probably psoriasis. She's had psoriatic arthritis for 35 years. Is this my immune system flaring? I know I should go to my gp but I can't face it, they've been so poor recently.

I will discuss it with Dr s next week.

I know I thought they would cheer us up. They cheered me Up! Hopefully so will do its thing for u, is Dh sperm good? I'm obssesed with everyone checking their dh sperm these days!!!

So tmrw I have to ring the clinic and book my first scan which will prob be next Friday. I've just popped my first hydroxy and asprin and the pred starts tmrw and then all injections on sat-we going away for the night so I've frantically packed my needles and sharps Box into the suitcase! its only 10-12 days of injections then it's all over! I always thought it would take weeks and weeks but I'm on the short protcol. I hope My postive mental Attitude stays throughout. I really hope to God this works, I just don't want
To loose all my hope like I did after mc 2 and 3. It's an awful place to be when u have no hope. I've finally got it back and I don't know if it will be gone forever if this fails! But I have prepared myself For it failing and told Myself I'll just have to Go again. Most don't work First time, must remember that.

Sorry for going on it, I know it doesn't apply to any of u!

Love the stories trying, been feeling like i m never going to get preg again so good to hear it can happen and hurray for your af arriving, go eggies go !!

Thanks Trying! Glad AF arrived! Acupuncture must have sped her up!

I love stories like that! Fills us all with hope!

That's last bit should have said 'drag like a bitch'!
Thanks Hula

Seeking wonderful news! So pleased. Mr s sounded a bit worried last time so must have felt great he was postive now. Hopefully u can relax?

Drtcc it's so hard after our histories to really enjoy pregnancies. But u have the backup, u have the drugs, and ur seeing the country speciliast. It will work out for u. Don't loose hope!

Snoopy - so sorry due date soon. I tem crying when I was meant to go on Mat leave first time around. It's so so hard. I hope u find a way to remember the day if u wish to. And again, don't loose hope u will get there too

2 lovely stories-one from acupuncture lady. 37 year old 2 miscarriages finds out v low amh. Fails ivf twice so then uses donor eggs and works. By now she's 40. Then has a natural bFp and has a baby?!
One story from my mum today (over afternoon tea-bad idea for eating healthy!) lasy adopted as tried for ten years and it was before ivf excited. Adopted a girl, then 4 months later BAM bfp! Now has another daughter!?

Bascially never lose hope girls....

On my end af just arrived! That means the drugs start scared and excited!

Yay, SO pleased !!!!

Phew! Everything ok. Measuring bang on 8+1 which is where he wanted it to be. Heart beat was strong. He's now pretty positive. I feel so relieved! Got another two weeks until I see him, that's going to drag like a bit hb

Welcome and congrats catmum, we ll do all we can to help you on this journey.

Snoopy sorry you re feeling down, the due date is such a hard time and i found all those raw emotions come flooding back for a good few weeks before the actual date. Maybe plan to do something on the day to remember the lo you lost (i put flowers on my grandmas grave as i liked to think that she was looking after my lo now). I found this helped and actually i felt alot better once the date has passed. Stay strong, it WILL happen for you.

Drttc - just take it one day at a time, you re on treatment and there s every chance this can work.

Seeking - keeping everything crossed for your scan.

I've had all three of my due dates pass me by, the first was definitely the hardest. I had three friends all due at that time and seeing there growing bumps made it all more real that I wand r pregnant anymore. Now all their babies are born it's much easier and I love them!

Drttc - just take it one day at a time. I'm sure you'll feel better when you get past your AF due date. You're on treatment, you e got your intralipids. This time is different.

Thanks for the info on Intralipids ladies!! She's coming tomorrow afternoon :)

Good lucj with your scan today Seeking!

Welcome Catmum! Congrats & looking forward to hearing lots of good news from you :)

Hey Snoopy, I'd not thought about the due date factor before. It actually broke my heart the other day (before I got BFP) & logged into an old pregnancy app... It read 'Welcome! You're 18 weeks pregnant!' Ouch... Remembering where you 'should' be is so painful.

I'm having a really tough day! With all the excitement of the BFP and months of positive thinking, I thought I'd be able to by pass feeling so low! Realistically, I know I'm in the absolutely most dangerous stage now, my history works against me, and stress/negativity is bad! Why is it so much easier to believe in others & not in yourself? I'm paralyzed by fear & have lost all my optimism :( Which hurts! Part of me is thinking this (being emotional) means AF is on it's way... Despite having no symptoms of AF! I just tend to get crazy sensitive beforehand. I've got to snap out of this! I got a 'pregnant 1-2 weeks' on clear blue which briefly made me so happy... But I know I'll be testing again tomorrow before Intralipids.

Someone shake me :(

Yeah catmum congratulations and welcome!

I don't know what's up with me, I was feeling so positive yesterday but today I feel like this journey is never going to end. Every mc just kicks me back to square one.

I think I'm getting more upset because the due date for my first is coming up. I just wanted to be pregnant again by that date and instead I'm getting over a third miscarriage. I feel like there's no light at the end of the tunnel

Welcome and congrats Catmum, you're in good company here, a wealth of knowledge and support from some very strong and brave ladies. Any questions - I'm sure someone here will have an answer for you. And if it's just support your after we're here too.

Come on Trying's AF!! Hope the acupuncture speeds her along!
Appointment is at 6.50..... Fingers crossed!

Hi catmum and welcome and congrats. The thread is a happy place to be right now so hopefully it will send u some good luck!
Are u under Mr s too?

Seeking what time is ur scan?

No af yet . Had acupuncture this am so hoping it will get it going!

Hi there. I'm a newcomer. POAS this morning and got a BFP . I've miscarried 3 times this past year, and have been diagnosed with high NK cells. I've started my prednisolone this morning, and see my doctor on Saturday morning. I just wanted to check in as I'm not sure about how I feel about the roller coaster coming my way!

Would love any tips or stories.

Thanks ladies

Drttc, they don't need to be refrigerated, so just keep them out of the sun.

Rosa - send your dh a big thanks from us, I'm always relaying stories from mumsnet to give my dh hope that it can happen. Big hugs to all our supportive husbands, it's tough all round.
Hula I really hope SO works for you and you can give ds a sibling, sounds like he's going to make a brilliant big brother!

I just left mine in the utility room! Don't think they need putting in the fridge...well I hope not!

Just got my Intralipids! Am I supposed to store them in any place in particular?

Oh hula, I'm sorry. It must be heartbreaking when he said that I really really Hope SO works for u. Ur doing everything u can, let's hope it's soon.