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Conception

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Immune / natural killer cell treatment when ttc or pregnant (aka the 15th pred thread)

991 replies

sunnyday01 · 06/02/2015 20:10

This is a thread for those diagnosed with high or very high natural killer cells and trying to concieve or are pregnant and taking steroids/intralipids etc

Newcomers very welcome

OP posts:
dildoos · 25/02/2015 21:42

Thank you all for your kind well wishes, dd was better in night last night Smile off school still until Friday bless her she is on 20mg prednisalone for her chest is there nothing this medication doesn't help?
Woohoo sunny! Back in the game is always fabulous!
Hula trying determind how and where you guys at?
Smidge how are you feeling now about having a break? I am feeling good about mine this month not really sure where I will be next month mentally but I am Cool with the break his month!
Agree trying I think the men will all pull ranks on the prederteranian cruise ship and ban us from DTD!
X

Tryingno1 · 25/02/2015 20:59

Yay sunny! I hope u get a bfp soon! We r out of syn now! Hula
I think we are though...
Wonder how rosa is getting on...

Dildoos hope ur little girl is ok xxx

Hula2 · 25/02/2015 20:19

Hey dildoos how s you re little girl ? i hope she was ok last night and keep her sats up and also that you re ok, i know how worrying it can be.

Smidge good you ve been able to have some relaxing time with your dh and good to hear the doc was still optimistic about you getting preg. Interesting she wasn t saying to use pred again, you had high nk on biopsy didn t u ? Did she say why ? I guess maybe she thought intralipids were enough - i d be interested to know as i still feel a bit uneasy about using pred.

Yay sunny you re back in buisness ! Grin

Trying i don t blame u about the pred, i didn t bother taking it either with my riculously early ov, what bad patients we are !

Hi eveyone else.

sunnyday01 · 25/02/2015 19:49

I'm back in the game! Popped some letrazole today!

OP posts:
Tryingno1 · 25/02/2015 15:27

Hey smidge glad to hear an update. Indulgent breaks are very much needed at times like this. I'm glad ur doctor was so positive. Good idea to take a break and then restart again when ur physically and emotionally ready. Enjoy the few months off and I truely hope u get a bfp and a sticky bfp next time!

Smidge001 · 25/02/2015 07:52

Thanks for the well wishes and encouragement. Trip to the snow sounds great to take a mental break Hula. Hubby and I have come away for 3 days to a lovely house in the country and just taken it easy. Played board games, had some wine (the positive of a bfn!) and read books looking out at the hills. Been exactly what we needed.

My fertility doctor called at last today (been promising every day since the negative result on Friday). She thinks we still should be able to get pregnant and that it's just a numbers game. At my age she says 25% of blastocysts make it to a successful pregnancy and we've only had 3 attempts so far, so she is leaning towards our issue being the embryo quality rather than implantation (despite testing high in the biopsy Hmm). She recommends when we do our frozen embryo that I have another intralipid infusion, and take the Clexane after transfer, but reckons another scratch probably isn't worthwhile (yay, not much fun!) and up to me if I want to use the pred. Personally she thought not but is happy for me to go ahead if I want.

I think we're going to give it a break for a couple of months now to try to let my body get back into the swing of a natural cycle. My first after IVF is always a bit screwy.

I asked her about the bleeding and she is still unconcerned, given I've had the laparoscopy and she confirmed my progesterone levels were high throughout the tww. Possibly the Clexane is making me more prone to bleed plus the pessaries might be irritating my cervix. (I don't actually believe this as it feels just like my normal pre menstrual feelings, but it's always nice to be reassured)

Hope the little one's feeling a lot better in the morning dildoos.

Tryingno1 · 24/02/2015 21:37

Haha! Great idea. Although our DP would come and would hate the amount us girls know about our sex life's etc!
Hope they stay at 94 and higher x

dildoos · 24/02/2015 21:14

Thank you lovelies!
Oxygen sats are at 94 at the moment any lower and I am off!
Hula good to see you had a nice break away. How was the snow? Other than white and fluffy Grin
We should all book a cruise ship together for this thread no one else and take a trip around the world in 80 days and see how many of us come back with a sticky bfp Grin I can dream anyway x

Tryingno1 · 24/02/2015 20:51

I love a good holiday hula. I feel like I need a long one to just forget it all...by all I mean stop counting tracking and living my life in 2 halves - before and after ovulation! Hope ur little one was ok with his mummy for the first time! No not taking the pred-I know I should but I don't want to! I'll test early and if its a bfp then I'll start taking it.

Dildoos hope she's better in the am! Xx

Hula2 · 24/02/2015 20:21

Hi all,

Dildoos sorry to hear your daughter isn t well, must be really worrying, really hope u don t have to go to a and e. Think there s alot of nasty coughs about this year as have had a few friends having similar with their LOs.

Sunny hope 5weeks is close enough to get going this cycle.

Trying sounds like u should def be covering ov time. Don t think u need to worry about it being every other day unless dh sperm count is low which is prob unlikely being you ve alreaady concieved three times but at least you can be sure when he gets it checked. R u taking pred this cycle ?

Fingers crossed Determined for good blood results.

I ve just got back from our ski weekend and it was lovely. Good to just switch of from ttc pursuits and just chill out.

dildoos · 24/02/2015 20:14

That we do I think this thread helps us all encourage each other along .
It is rather stressful kept waking to check her last night xx

Tryingno1 · 24/02/2015 20:07

Dildoos sorry to hear the little one is unwell :( I hope she picks up and ur not panicking too much :(. Bless her. must be frightening having a little one if they get poorly..cant imagine

Most women don't ovulate the first month post miscarriage so don't worry...u will next month.
I am hopeful overall,I just don't know how many years this saga will continue for...not sure how long I can take it for! But I never thought I would cope with another miscarriage...and I did at number 3...so just shows we do all just plod on!

dildoos · 24/02/2015 19:29

Hi ladies.
I am ok thank you determind.
Trying sorry to see you are loosing hope I still feel positive for us all, sunny I hope you ovulate a week late so that will be 6 weeks and you can try or be on time and louise says that's fine?
I am day 19 still no ovulation medium or high on my monitor?
Dd unwell has awful chest had antibiotics and now on steroids and monitoring her oxygen sats esp at night as they are dipping considerably. Been told that if it happens tonight a and e so I have everything crossed that all will be well.
Other than my non ovulation month wondering if because first cycle post MC? Or if machine faulty? Either way doesn't matter as was not going to take pred this month anyway.
How is everyone doing? I agree it's mighty quiet in here at the moment.
X

Tryingno1 · 24/02/2015 12:22

Hi sunny.glad u ok on the hydroxy and I hope u can start sooner rather than later!

Yes it's been quiet on here as dont think any of us have much to say! I'm still ttc and loosing a bit of
Hope that it will happen naturally as each month passes! Hula thanks for ur advice-intresting that u can ovulate on the day of ur LH surge, the day after or 2 days after? Was this all in a similar time frame? I usually bd the day before surge and then daily after for 3 days. Thought that would cover it but wondering if I should just do alternate day instead so all based are covered and DH sperm had some rest time! I suppose when he sends his sample off I will know if that's a problem
Or not!

sunnyday01 · 24/02/2015 09:04

Hi everyone - sorry i've not been around much but haven't felt i can contribute much whilst waiting around!

Hydroxy has been fine, have had no side effects (or none that I have noticed). Had my first set of blood tests last week too, so hopefully they are all ok (you have to have a liver and kidney function test every 3 months on hydroxy). AF looks to be starting today, so don't think I'm going to be able to try this month as it needs to be in your body 5-6 weeks before you can try, I've been on it 3 weeks on Thursday, so assuming 2 weeks to ovulation - its going to be very very close to being 5 weeks! In fact i could miss it by a matter of days - will seek some advice from Louise I think.

Hope everyone else is doing ok

OP posts:
Tryingno1 · 22/02/2015 19:14

Let us know how ur bloods r determined. And let us know wot the nutriontist says too! I know low fat diary isn't great but I can't cope without my decaf Latte and yog ESP when dieting!
I weighed myself yest agast! Have put on 6 pounds!!! So mega dieting begins tmrw! Dear me.

Determined123 · 22/02/2015 10:12

Hey there

Hula you have your ski wknd? Where did you go? V.jealous!

Hi trying I am good thanks. Been really busy lately and trying to avoid any baby/ttc thoughts and just focus on other things...think it's helped! Great news on your latest scans and dh doing his tests!

Have booked my re do of bloods for next week, no idea what they will say!? I have managed to get my self a cold though and worried that may effect results? (I haven't had a cold for I reckon 18months) so wondering if something has changed?! Prob not!! Got an appointment with a nutritionist while I am in London to check I am on the right track...

Dildoos how you doing now? Sunny how is hydroxychloroquine so far? And Rosa SO? It's been all go lately ;)

Xxx

Tryingno1 · 22/02/2015 10:05

Oh lovely hula! Have a great weekend! Hope u manged to enjoy urself!
Thanks about the ecwm-I have the same pattern, it's not ecwm the day of surge and day after which I think it is odd, but urs sounds the same!

Waves to everyone x

Hula2 · 21/02/2015 18:30

I tend to have 3-4 days ewcm, tho it tends to go more thin and a bit less obvious on day of positive opk and day after (which would usually be ov day). I charted for about 6mns and i did get a temp shift either one or two days after positive opk. I do get the feeling sometimes i ovulate late on positive opk day rather than the day after and I did a monitored cycle which supported this. It can be nice to comfirm ov with temp shift (and also that you haven t ov with low temps) so i tend to just do it a few day b4 ov and a few days (assuming ds doesn t have me up too much).

I think if you bd for 2-3 days after u last notice ewcm you ll cover bases.

I m on my ski weekend and so nice to just chill out (tho do miss my little boy!).

Hope you re all having a good weekend.

Tryingno1 · 21/02/2015 11:25

Hula - when ur cycle is behaving when does ur ecwm stop? Do u chart too? I don't want to get into temping coz I'll drive myself mad! But I keep worrying I've missed ovulation and that's why not preg!

Tryingno1 · 21/02/2015 08:53

Morning sunny! Hope ur enjoying having a break! How's ur swimming etc going?

sunnyday01 · 20/02/2015 23:20

Hi everyone! Just a quick check in yo see how everyone's doing?

I'm sitting back a bit this month as just waiting to start again so nothing exciting to report!!

OP posts:
dildoos · 20/02/2015 22:20

Sounds like the perfect excuse to me Grin
How are you feeling at the mo?
I am day 15 still no ovulation but def not taking the drugs this month as just can't bare the thought x

Tryingno1 · 20/02/2015 21:25

No I didn't! I just always react to
It a bit with a mild headache. I know ur not supposed to ;) But I have drunk on it before coz I really wanted to get pissed post ercp! Wasn't the best idea had a stinkinh headache after 2 glasses of wine!

dildoos · 20/02/2015 21:04

I take it you possibly drank on metronidazole?! It can make you really I'll bless you! Hope the headaches gone. X