Immune / natural killer cell treatment when ttc or pregnant (aka the 15th pred thread)

So scan showed that I'm not as far along as I thought... That always makes me anxious. I'm 5+4, BUT. We did see a teeny little heartbeat via vaginal scan! So relieved. That'll be short lived but for now I'm a bit more relaxed. Will still see DrS on Thursday and then got ILI on Friday. Repeat scan at local epu on 28th.
Fingers crossed and a little prayer that things continue to improve and develop!

Best of luck today Seeking.. Think of you. When you know what's happening call Louise and see what she says about seeing Mr S later this week.
Trying- thanks, I know. Hoping nothing to worry about but just feel totally symptomless again except this colour .. And had horribly nightmares about miscarriage - fear or premonition? I don't know I guess will be like this all the way if I'm lucky enough to get all the way.
Nausea is awful - you poor thing. Hope you find ways to ease it. Assume you tried the wrist bands etc. x

Sorry seeking, how stressful. When is ur next scan. Lots of people spot and the progesteronr can irritate ur cervix. Don't give up hope yet!

Rosa, same for u. U had a scan showing ur ahead! Hopefully today scan will put u at ease let us know!

Determined if ur there how did u cope with this awful naseau of metformin? I'm on it for a pa1 mutation (!) not pcos and on 500 twice a day. Feeling very sick!

More of the same here. Pretty sure that me onto mc4 . I guess the scan tomorrow will tell me one way or the other. Feel stupid for getting my hopes up and thinking by some miracle we'd be ok. But I guess there's a reason Dr s specifically says not to get pregnant before starting the drugs.
If I do miscarry again should I still see Dr S on Thursday??
Feeling very down.
Hope you're ok Rosa, we both need to try to relax. Sending good vibes your way

Seeking ... I've now the same... Light yellow. Really worried. Hope it's not because I walked for half an hour in the sun from the station when should be resting. Seeing Mr S tomorrow .. Just have to take my own advice and try hard to relax and keep the faith ... X

Big hug Seeking. It's awful I know.. Always been a worry sign for me. I'm not out the woods yet though but did have some at your point and it went. I doubled up on cyclogest then and don't know if it's coincidence. The hard but important advice to take it not to stress and relax. Everything crossed for you x

Had some suspect looking discharge when I wiped after a wee this morning... Water brown...naturally now very anxious and assuming the worst

Had some suspect looking discharge when I wiped after a wee this morning... Water brown...naturally now very anxious and assuming the worst

Hula- that's great you've managed dairy too. I tried for a few weeks but caved with eggs. Now have some every day but try limit it- eg don't kick myself if I have a pret chicken salad. Or gluten-free cake ;)
Trying - I know, I know! Just had a lot of fatigue so too much time too! Mr S says cyclogest until 16 weeks so will need to get his view. X

Rosa u need to step away from Google! Ur only going to drive urself mad, I got told by my consultant yest (well my DH was told that I had to step away from Google!) there's too much info out there and most of it unhelpful. So I'm having a Google free life from now (wonder how long it lasts!).
From my understanding prog naturally gets made by ur placenta week 10ish so u don't need extra...so week 12 is quite a normal time To stop. Every week u have a good scan ur chances of it going wrong and hugely dropping!
Happy bday for next week, I'm gonna be on my 2ww of ivf for mine

Yep i know sometimes its bad to google/forum surf too much esp when preg but really hard when you re also looking for reassurance. Did you have a good luteal phase in your cycles, if so i wouldn t worry too much about the prog, i think its an extra precaution and really its the pred and intralipids that will be having most effect on immune issues.
I ve cut out diary and gluten in the last month too (and feel better for it) so hoping that will help too.

That's right - you're only a year ahead of me .. My birthday is a week today .. Think will get a reassurance scan in the morning so have a hope of enjoying some of it. Just spent the last hour reading other random forums and got myself stressed again. Different opinions on how long you take cyclogest for(some say through to 3rd tri?), how much (too much can cause development issues of sex organs?) and also how (read you need injections if immune issues to ensure it absorbs). I'm taking 400x2 pessaries. Then I started reading about 12 and 20 week scans - oh dear. Getting too far ahead of myself!
Hope you have good luck this month Hula .. I'm sure all the vits etc are helping with egg quality too. I've a feeling my cutting out gluten has helped too. X

Just turned 40

Yep i think they both help with cytokines and my cytokines were nt too bad (31.8). Just hope i don t get a flare.

Ov today or tomorrow so we ll see how i go this month but the beer book said he saw best results 3mns after the humira as the cytokines can affect egg quality.

Hula - does the pred and /or intralipids not help with cytokines too-or is it just NK? Mine were v high and as had allergic reaction to Humira only went down 40 to 38 I think as couldn't take second dose. I'm sure and really hope everything you're doing is helping.
How old are you if you don't mind me asking? It's do hard to make a plan as you don't really know how you'll feel until you're actually faced with a choice. But whatever it is it will be right for you - really hope it all works out x

Well plan is 6mns but who knows when we get there....i m thinking of doing dhea too to improve egg quality as much as poss and once cytokines results are back maybe a few goes at SO if they have come down. Got to live life too someday and since my fsh had crept up to 10 the clock is def ticking for me !

Trying - I injected in my stomach for SO and was terrified before but was totally fine!
Worth knowing Healthcare at Home charge more on a Sat. But next week the nurse will bring my prescription with her to save me being in day before as will be in London so worth asking if possible for you too?

Thanks hula. How r u feeling about trying? Are u still going for 6 months more and then stopping or is that still up for debate?

Also don t know if you ve injected yourself before but i did mine over my stomach and it was fine.

Thanks hula!
Out of all the crap I'll be doing that was stressing me out the most
Hopefully I can plan it for a day when I'm not at work!
Have a lovely weekend.

Hi Trying - good to hear from you ! Exciting you ll be starting soon but i understand how daunting it can seem too. Good plan to just take it a week at a time. Do keep us posted on progress.

My humira came from healthcare at home and if you order by 3 you could get stuff next day and chose 7-1 or 1-7 i think. They did deliever on a sat morning too. It does need signing for. It did come in a plain box but mine needed refridgerating straight away so i didn t dare send it to work in case someone else tried to be helpful and opened it ! Good luck.

Ps thanks rosa. Will keep u guys posted. Not really expecting it to work out first time around, but there's always hoping. Feels a bit unfair I have 2 hurdles to jump now. I feel stressed about getting a bfp and wonder if it will ever happen and if ivf will work! and then I'll be a mad woman when I do!!

Has anyone had anything deliered from healthcare at home? Do they do weekends and after work hours too?

Thanks Hula - having stop myself from changing my internal theme tune from que sera to zipadeedooda!

Trying - really good to hear from you .. I know how it is when you have to learn about yet more stuff and another programme.. It's daunting but it sounds like you're in great hands and they are covering all bases... Plus 2 weeks is no time before things start happening! Really looking forward to hearing how you go and everything crossed for you of course :) loads of luck xxx

Hey guys

Sorry for the huge radio silence. I've needed a few weeks to sort my head out and come to terms with my new plan! But and u have all been in my thoughts daily (literally) my virtual "friends".

Rosa-so glad for u. I've been logging on mainly to see ur progress Really over the moon. Am sure things will keep going well and it's only a few more few more weeks of madness u will need to tolerate and hopefully after u will feel calmer past 12 weeks although I'm sure fear will never go.so glad.

Hula happy bday! Hope u had a fun day. Well done for being brave taking the humira and I hope it works it's majic for u soon.

Determined im glad the break did u good. Postive mental attitude and all that....I hope when ur ready to go again u feel strong and ur body feels ready. Hope u been having lots of laughs :)

Seeking, good luck for ur scan. Drtcc, good luck for ur next cycle!

Hope amazing, ur nearly there! So happy for u. Will be our first graduate from the bunch of us! Hope ur getting some sleep.

As for me, I start my ivf cycle in 2ish weeks. The ivf clinic discovered a few more issues, meaning I need metformin and hydroxychloroquine (12 weeks) and clexane throughout pregnancy and 6 weeks post natal too for the clexane. Like NK cells, these are contresversial tests/ not loads of evidence and hence why Shehata prob doesn't test for them. But now I don't really feel like his patient anymore! I'm in a totally diff world. So I'll be taking pred intralipids asprin clexane metformin and hydroxy!!! The whole ivf process is so confusing! Just going to take it week by week, and hope I manage it all with work. It's quite intense. Wish me luck!

Xxx

Made my day to hear your news Rosa, so so glad its still all going ok.

Good luck for monday seeking - rooting for you too. x