Immune / natural killer cell treatment when ttc or pregnant (aka the 15th pred thread)

SUNNY!!!

Omg what amazing news!!! Were you trying but foregoing the pred? What cycle day are you?

Ahhhh yayy!!!!

Thanks rosa. It's so hard isn't it! I so want to be preg again but I'm kinda dreading the anxiety and worry I'll have. My acupunture lady will be seeing me daily to help calm
Me down!!
Good luck with scan today rosa, ur so close out of trouble zone it's so wonderful. Seeking hope u been calm and hope the scan tmre shows the bean has grown and doing well. Do let us know.
Hope everyone else ok

• do to you

Trying - you have to remind him what the drugs to you.. So he can know (without telling you in the moment) that it's not really you sometimes when moods get extreme. And thank him lots for looking after you - my DH is a legend but says least he can do given what I'm going through. But also had more moments than usual because it is just relentlessly tough. Of course you know all that, just empathising really. Hang in there. Let's hope we keep the positive momentum of this thread going x

Seeking I've got everything crossed. And u rosa.

Hula I get heavier boobs about 6days post ovulation till AF comes. I used to think it was a BFP sign but never was! My first bFp boobs were painful rather than heavy/swollen.

Found an app where u can tick off and add all ur drugs! Was worried I would forget my drugs as when af arrives I'll be on 9 diff drugs minus the vitamins !!!

This ivf crap is really hard on relationships, Me and dH r mega strong (touch wood, please don't change!) but we been bickering recently. In 5 years of marriage I can count my bickers on one hand. Oh well, only a few more weeks to go! We both know are stress levels r slightly hugher so just rolling with it and accepting the stress! I hope he's willing to do this again if it fails

In 7 weeks tomorrow Drttc. And I can totally confirm that time is going soooo slow!! I'm living my life wishing the week away! I just want it to be Thursday so I know where I am with the scan... Praying, crossing fingers, talking to the bean trying to encourage it! I'm losing he plot!

Hope you're joining us soon Drttc and that your progressing on o second trimester Rosa!!

We've also just though sod it with regards to the cost of everything. It's so bloody expensive but we'll figure it all out! What's £500 for the harmony when you've just spent thousands getting to this point!

Ps I can.. This has been the looooongest 10 weeks ever.. Ever day feels like a week! Think the next 2 2/12 (assuming things ok) will feel like 6 months. It's funny how we all go through the same time but it can feel so different depending on what's happening in your life !

Drttc - it is £500 in Edin.. £450 with Mr S and Spire up here is £700! It's cheaper and quicker for me to get done here as no travel. It's meant to be so accurate it's almost as good as a diagnostic so will (I so hope!) give reassurance - but extremely nervous result could be bad. We can't afford any of this anymore but just throwing everything at it and not going on hols etc helps. Hope you find a way too when it's time x

Have added you in, Seeking :)! Are you about 6 weeks? Keep the updates coming!

Rosa, it would be a dream to join you at the end of the month! I can't believe you're already at 10 wks?! And you lucky thing going in for the harmony scan... SO EXCITING! Love this :) I looked up that scan the other day and it's about £500 isn't it? Wayyy too expensive for us considering we'll need to pay for Intralipids, but who knows.... In the excitement of selling my old flat I may 'misplace' £500 or so ;)

Has anyone ever followed TTCers on Instagram? I can't decide if this branches into 'unhealthy obsession' :-/

3rd Trimester
Hopender- (38 yrs old) 7 miscarriages, one DS, Was on pred, cycolgest, baby aspirin and intralipids. Now only baby aspirin! (29 wks)

1st trimester
Rosa (39yrs) - 3 MMC
(11.5, 6.5, 7.5). 6 months ttc on treatment. On complex programme for high NK, cytokines and thyroid antibodies (hydroxy, pred, intralipids)- had allergy to Humira. Also on SO programme. (10wks)

SeekingMiracles (30)
3mcs (5+3, 4+2 and blighted ovum 6+4). On treatment programme for high Nk cells and PT Gene variant. Pred, intralipds, fragments and aspirin. Currently crossing fingers and toes that this pregnancy works out. (6wks)

TTC
Sunnyday (32 yrs)- high nk cells - hydroxy, pred intralipids - 3 mc (1 on treatment) also doing super ovulation - round 1 (got bpf on round 5 last time)

Tryingno1 (30 yrs old)- 3 mc. Ttc since April 2012. 5.5 weeks, 9 weeks, 6.5 weeks. High nk cells. Pred and intralipds. pa1 mutation. C4/m2 mutation. Hla dq match and low LAD. (Last ones done by ivf clinic) pred and intralipds. Along with asprin, clexane, metformin, hydroxy. discovered low sperm count. Starting first ivf injection in 1/2 weeks.

Hula2 (39 years) - one DS (took 18mns with low amh but no other probs), one MC at 9wks, ttc no 2 19 mns (12mns since last mc), low amh, borderline cytokines, high nks, on complex nk plan (pred, intralipids) about to do Humira for cytokines.

Drttc- (28 yrs old) 3 MCS (6 wks, 4wks 2 days, 5.5 weeks), very high NKC on complex treatment plan: hydroxy 2x day, 25 mg pred from ovulation, add cyclogest on bfp & Intralipids every 4 wks until 16 wks. Testing on May 28th.

lilliesandchocolate (32) 1 mc, 1dc, 5mc, 2nd dc on pred and cyclogest and the vitamins, 1mc. pred,cyclogest,intripalids and the vitamins.

WTTC

Determined123- awaiting (retest) results. 4mcs (2 on treatment). PCOS, Borderline NK Cells and v.high thyroid antibodies.

Thanks Drttc- very kind of you - and impressed with all the detail you got right! Hopefully you can go to my category before the end of the month (and I can stay there!). Also Seeking.. Thinking of you ... Hope you're managing to stay sane and positive and of course still everything crossed for you.
I've a scan tomorrow night as part of the Harmony test. Nervous as ever.. X

I need to be added to fort trimester please Drttc

SeekingMiracles (30)
3mcs (5+3, 4+2 and blighted ovum 6+4)
On treatment programme for high Nk cells and PT Gene variant. Pred, intralipds, fragments and aspirin.
Currently crossing fingers and toes that this pregnancy works out.

Whoops just spotted mistakes! Sorry! Here it goes again...!

3rd Trimester
Hopender- (38 yrs old) 7 miscarriages, one DS, Was on pred, cycolgest, baby aspirin and intralipids. Now only baby aspirin! (29 wks)

1st trimester
Rosa (39yrs) - 3 MMC
(11.5, 6.5, 7.5). 6 months ttc on treatment. On complex programme for high NK, cytokines and thyroid antibodies (hydroxy, pred, intralipids)- had allergy to Humira. Also on SO programme. (10wks)

TTC
Sunnyday (32 yrs)- high nk cells - hydroxy, pred intralipids - 3 mc (1 on treatment) also doing super ovulation - round 1 (got bpf on round 5 last time)

Tryingno1 (30 yrs old)- 3 mc. Ttc since April 2012. 5.5 weeks, 9 weeks, 6.5 weeks. High nk cells. Pred and intralipds. pa1 mutation. C4/m2 mutation. Hla dq match and low LAD. (Last ones done by ivf clinic) pred and intralipds. Along with asprin, clexane, metformin, hydroxy. discovered low sperm count. Starting first ivf injection in 1/2 weeks.

Hula2 (39 years) - one DS (took 18mns with low amh but no other probs), one MC at 9wks, ttc no 2 19 mns (12mns since last mc), low amh, borderline cytokines, high nks, on complex nk plan (pred, intralipids) about to do Humira for cytokines.

Drttc- (28 yrs old) 3 MCS (6 wks, 4wks 2 days, 5.5 weeks), very high NKC on complex treatment plan: hydroxy 2x day, 25 mg pred from ovulation, add cyclogest on bfp & Intralipids every 4 wks until 16 wks. Testing on May 28th.

lilliesandchocolate (32) 1 mc, 1dc, 5mc, 2nd dc on pred and cyclogest and the vitamins, 1mc. pred,cyclogest,intripalids and the vitamins.

WTTC

Determined123- awaiting (retest) results. 4mcs (2 on treatment). PCOS, Borderline NK Cells and v.high thyroid antibodies.

3rd Trimester
Hopender- (38 yrs old) 7 miscarriages, one DS, Was on pred, cycolgest, baby aspirin and intralipids. Now only baby aspirin! (29 wks)

1st trimester
Rosa (39yrs) - 3 MMC
(11.5, 6.5, 7.5). 6 months ttc on treatment. On complex programme for high NK, cytokines and thyroid antibodies (hydroxy, pred, intralipids)- had allergy to Humira. Also on SO programme. (8wks)

TTC
Sunnyday (32 yrs)- high nk cells - hydroxy, pred intralipids - 3 mc (1 on treatment) also doing super ovulation - round 1 (got bpf on round 5 last time)

Tryingno1 (30 yrs old)- 3 mc. Ttc since April 2012. 5.5 weeks, 9 weeks, 6.5 weeks. High nk cells. Pred and intralipds. pa1 mutation. C4/m2 mutation. Hla dq match and low LAD. (Last ones done by ivf clinic) pred and intralipds. Along with asprin, clexane, metformin, hydroxy. discovered low sperm count. Starting first ivf injection in 1/2 weeks.

Hula2 (39 years) - one DS (took 18mns with low amh but no other probs), one MC at 9wks, ttc no 2 19 mns (12mns since last mc), low amh, borderline cytokines, high nks, on complex nk plan (pred, intralipids) about to do Humira for cytokines.

Drttc- (28 yrs old) 3 MCS (6 wks, 4wks 2 days, 5.5 weeks), very high NKC on complex treatment plan: hydroxy 2x day, 25 mg pred from ovulation, add cyclogest on bfp & Intralipids every 4 wks until 16 wks. Testing on May 28th.

lilliesandchocolate (32) 1 mc, 1dc, 5mc, 2nd dc on pred and cyclogest and the vitamins, 1mc. pred,cyclogest,intripalids and the vitamins.

WTTC

Determined123- awaiting (retest) results. 4mcs (2 on treatment). PCOS, Borderline NK Cells and v.high thyroid antibodies.

Tryingno1 (30 yrs old)- 3 mc. Ttc since April 2012. 5.5 weeks, 9 weeks, 6.5 weeks. High nk cells. pa1 mutation. C4/m2 mutation. Hla dq match and low LAD. (Last ones done by ivf clinic) pred and intralipds. Along with asprin, clexane, metformin, hydroxy. discovered low sperm count. Starting first ivf injection in 1/2 weeks.

Thought I'd revive this as things are heating up and I think it's hard to keep track of everyone's history. Feel free to add your details and repost or correct me if I'm wrong!

Thought I'd update the list with my results!

3rd Trimester
Hopender- (38 yrs old) 7 miscarriages, one DS, Was on pred, cycolgest, baby aspirin and intralipids. Now only baby aspirin! (29 wks)

1st trimester
Rosa (38 nearly 39yrs) - 3 MMC
(11.5, 6.5, 7.5). 6 months ttc on treatment. On complex programme for high NK, cytokines and thyroid antibodies (hydroxy, pred, intralipids)- had allergy to Humira. Also on SO programme. (8wks)

TTC
Sunnyday (32 yrs)- high nk cells - hydroxy, pred intralipids - 3 mc (1 on treatment) also doing super ovulation - round 1 (got bpf on round 5 last time)

Tryingno1 (30 yrs old)- 3 mc. Ttc since April 2012. 5.5 weeks, 9 weeks, 6.5 weeks. High nk cells. Pred and intralipds.

Hula2 (39 years) - one DS (took 18mns with low amh but no other probs), one MC at 9wks, ttc no 2 19 mns (12mns since last mc), low amh, borderline cytokines, high nks, on complex nk plan (pred, intralipids) about to do Humira for cytokines.

Drttc- (28 yrs old) 3 MCS (6 wks, 4wks 2 days, 5.5 weeks), very high NKC on complex treatment plan: hydroxy 2x day, 25 mg pred from ovulation, add cyclogest on bfp & Intralipids every 4 wks until 16 wks. Testing on May 28th.

lilliesandchocolate (32) 1 mc, 1dc, 5mc, 2nd dc on pred and cyclogest and the vitamins, 1mc. Now hoping dc3 happens with pred,cyclogest,intripalids and the vitamins.

WTTC

Determined123- awaiting (retest) results. 4mcs (2 on treatment). PCOS, Borderline NK Cells and v.high thyroid antibodies.

Hi ladies! I'm quietly reading along :) To all of you who are ttc or waiting- I feel you! You're are so inspiring and I love that we can give each other that push forward when one of us feels weak/down. You're all amazing!

Rosa and Seeking- so happy things are going well! Love following a positive story :)

As for me- I'm in the clear blue trial at the moment which means I got a free ovulation kit. Last month I couldn't detect ovulation with the kit, but this month I got a peak fertility smilie on day 12 :) That in itself felt like a victory! Now on CD14 so officially in the tww. Well more like 11 day wait because I have a 25 day cycle! I'm not even going to bother symptom spotting because I really worked myself up last month with it. Louise had told me to start progesterone on CD16, and I've decided I'm not starting steroids until CD19. I'm delaying the steroids so that I'm only on them for 5 days instead of 10 (if I get a bfn) because I'm convinced they are what messed up my cycle!

~sending positive vibes :)~

The move is kind of helping to distract me. Gonna have a busy few months!

Totally echo your point Hula - I think when we all finally get our babies we're going todo much more thankful and appreciative of every little second.one day at a time is all we can do.

My boobs only ever hurt in tww when I'm pregnant. It's the first giveaway.

Trying thanks so much for explaining the intralipids. I've asked my doctor whether she thinks we should use that too but I have a feeling she might say the pred and clexane are probably enough for now seeing as I haven't actually been diagnosed with anything.

Trying - its understandable you feel this way but when you finally get your bubs (and i really believe you will) you will treasure each moment so many more times over because of the journey you went through. I believe that those who fought tooth and nail to get their babies make the most amazing mummies. I know it won t seem much consolation now but stay strong and just take it day at a time. That is all anyone can do. Oh and try and ban yourself from google (hard i know!) maybe try to get stuck in a good book and divert yourself to a few pages of that if you feel yourself weakening !

Rosa so glad you could enjoy your birthday. Wednesday is not far now so stay positive. (Also try not to worry about the no symtpoms, i had very few with ds until third tri).

Seeking what a nightmare with the move, i guess up side is it may help keep you distracted.

Sunny good to hear from you and glad you seem more chilled, fingers crossed for a good res of dh test, sperm can really vary loads either way.

Determined i m going to ring and see if results are back tomorrow. Re the resvertrol yes its the stuff in red wine but sadly nutristionist rec i take in supplement form (200mg twice daily) instead ! I m getting supplements all online (amazon for alot of them).

A random question for you ladies, do you get breast sensitivity in the tww and if so when ? Last couple of cycles i ve had really sore boobs from about 3dpo to af. Don t know if this is a bad sign as usually only got full boobs in the week before af. My progesterone was good last month (when i also had sore boobs) so i dont know what to think. Prob should just not try and overanalyse things !

Seeking how stressful! Hopefully the move to the new house will be a sign of a start of good things for u :)
Rosa glad u had a good bday. When is ur next scan?
I'm struggling to not go google mad! Am worried I'll get a bfn at the end of it all and ivf won't work. Then there's the miscarrying if it does work. Only got a 30 percent chance of it working according to national stats..I keep worrying between failing ivf and then miscarrying after a BFP! Need to switch my brain off . Really wish we had just gotten preg again like the other 3 times. Sometimes feels like the world is telling me to give it up. Surely infertility and miscarriage isnt something easy to overcome...
Sorry for being down in the dumps!

Try not to let it worry you Rosa - I know that's hard. You're scans have all been very encouraging. You are so close!
I agree that the Deliciously Ella and Hemsley and Hemsley books are brilliant. My diet has taken a bit of a nose dive lately - we're in between houses at the moment, living out of boxes until remove into our permanent home next month. Just another stress to add Ito the mix. Perfect timing! Not!

Seeking - I know I got that answer too, just I have had symptoms..hmm. I've to start weaning off at 10 weeks so from Wed, so will be interesting. Let's just keep smiling when we can and hoping!
Sunny - nice to hear from you. Sounds like you've got a calm head on things all considered. Agree I'd not worry about drugs at this stage - so many are fine jumping on the medication from BFP. Nutrition fascinates me too. Totally believe it's as powerful as drugs if you know what you're doing.. Can be time consuming and expensive though. But I'm just trying to eat colourfully, without gluten and chucking in a teaspoon of macha and spirulina when I make a juice - lucky if that's half the week! X