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Conception

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Immune / natural killer cell treatment when ttc or pregnant (aka the 15th pred thread)

991 replies

sunnyday01 · 06/02/2015 20:10

This is a thread for those diagnosed with high or very high natural killer cells and trying to concieve or are pregnant and taking steroids/intralipids etc

Newcomers very welcome

OP posts:
Seekingmiracles · 21/05/2015 10:22

Rosa you are so so close. I'm wishing the next 2 1/2 weeks away for you. You've really helped me to be positive in the last few weeks, just seeing your progress encourages me. Keep strong.

Just had my scan. Heart still beating away and grown as it should. I can relax at least for the rest of the day before anxiety kicks in again! Another week until I see Dr S again - I pray that all continues as it is. Bloody hell this is stressful!

Really hope this is the beginning of a stream of luck and good news floor he rest of you ladies

Rosa27 · 21/05/2015 09:19

Thanks Trying. We all get our bravery tested don't we - so tough. Hope you get answers .. I never went to a dietician - wish I had though.
Seeking - thinking of you too... Everything crossed xx

Tryingno1 · 21/05/2015 09:06

Seeking hand holding for today Flowers

Tryingno1 · 21/05/2015 09:05

Oh rosa, u choked me up. It's so overwhelming. Ur nearly there. Keep being brave

Sunny hope u got Louise!

Hula anyone who been to dietician. I take omega 3-it's from Holland and barrat 1200mg and has epa 648 and dha 432. Is this ok??

Rosa27 · 20/05/2015 22:18

Thanks Hula, Seeking, Sunny, Trying. Feel a bit weepy tonight .. Was so scared tonight. I never let them switch the monitor on as still traumatised by images showing no heart beat .. Tonight I looked and my wee baby's hand waved at me .. I can't avoid crushing heartbreak now if things don't keep going well...
They said they could test for more things like extra or missing chromosomes if we found out the sex so said yes. Not sure will share that, but given it's taken me to 39 to get here, and given I don't know I could go through all this again no matter what, I think I do want to know. Years ago I never though I would but the last few years panned out very differently to how I imagined .. You have to do what feels right I guess.
It's amazing how great it feels to read good news for you guys too, and for positive steps and mind sets .. Will be over the moon if we can all start moving through the ranks this year towards our dream. Sorry I'm OTT emotional right now x

Seekingmiracles · 20/05/2015 21:10

Excellent news Rosa!! You're sooo very close now! Keeping everything. Crossed for your harmony results. Are you finding out the sex of little one? Xx

Tryingno1 · 20/05/2015 20:46

Either ur results were wrong, or as my ivf guy said its all a game of chance and even if there one sperm in there u can get a BFP! Which was his explanation as to my 3 quick pregnancies followed by nothing for 10 months! It's such a strange bizzare world I think so much noone knows about fertility.... when it's meant to happen I think maybe it just does and it all fits into place. My acupunctre lady told me today of a woman who had pred intralipds etc twice it didn't work. So went solo on nothing and has a baby?!! How bizzare!?

I have a great feeling for u. Yay! Let's hope we have another bFp very soon! This thread was a bit depressing a few months ago! And now it's all go ??

Hula2 · 20/05/2015 20:43

Rosa fantastic ! A good scan at 10 wks is a REALLY good sign. I had planned on having the harmony test with my mc last year and it sounded very accurate for picking up the trisomy esp downs. Your odds are still far far more likely everything will be fine. Keeping everything crossed for you (and sunny and seeking) for happy and healthy LOs. Go ladies !!

sunnyday01 · 20/05/2015 20:34

Thanks everyone - I've got everything crossed that this is it. Trying not to think about it too much as its early days still! (Easier said than done!)

Trying - can't believe it after results - they must have been wrong! You're so close to your ivf starting - it's very exciting! Great idea about the app too!

Fab news about your results Rosa - keep hanging in there!

Let's hope this is the start of dome good news for all on this board - we've been waiting long enough!

OP posts:
Tryingno1 · 20/05/2015 20:26

Oh my! Don't check the board for a bit and we have another bfp! Amazing congrats sunny. Don't worry about not being on the drugs, ur on hydroxy and u will get the others in u soon. So exciting! No ivf after all! I hope this thread is finally picking up and getting some good news after all the crap we have all been through! Whoopy!
And rosa excellent news re scan, so close to 1st trimester ending!
Seeking hope ur ok re tmrw x

Rosa27 · 20/05/2015 20:22

YAY Sunny!! Congrats !! Smile
The momentum is finally building - so excited. I had super faint results too at the start.

My scan tonight put me at exactly 10 weeks. The blood was taken for Harmony and I now need to wait 2 weeks for results and 2 1/2 for my dating scan. So nervous about Harmony results .. Has anyone out there ever had it?
X

Hula2 · 20/05/2015 20:20

Oh and try not to worry about the flight, i found out i was pg with ds the day after we arrived in canada so had two long haul flights b4 6wks. The relaxation of being on hol should cancel out any negatives.

Hula2 · 20/05/2015 20:16

Great news Sunny ! Sooooooo pleased for you.

Rosa hope your scan went well.

Wow trying that s loads of drugs to try and remember, good idea getting an app. Really hope this works for you 1st go.

Seekingmiracles · 20/05/2015 19:47

I asked DrS about the flight, he said it's fine. Just get some flight socks!

sunnyday01 · 20/05/2015 19:31

Thanks seeking to, going to do another cb digital inn he morning just to make sure!

Luckily I'm not a big sun worshipper as have very fair skin (as does dh) but I'm worried about the flight and it starting something, probably totally irrational!

OP posts:
Seekingmiracles · 20/05/2015 19:03

Sunny....
First off CONGRATULATIONS!!Smile
Secondly - it always happens when you're not 'trying'. I got my bfp on my second month 'off'! Bloody typical! As a result had to wait to get drugs (4 days to be precise). I also did a tesco test which was faint and the exact same worries. I also ha a holiday a week after my bfp, just stay out of the sun when you can and make sure you drink loads to stay hydrated.

sunnyday01 · 20/05/2015 18:44

Lol - not sure I'd do that! The tesco one must be crap! I'm just worried I haven't picked it up earlier. My main worries at the moment are

  1. Not discovered early enough to get maximum drugs in me
  2. Feint test means it's not strong enough
  3. Literally no symptoms!
  4. Going on holiday to Turkey in 3 weeks - worried that flight might trigger something
OP posts:
Drttc · 20/05/2015 18:36

Sounds like you're in a good position meds wise, sunny. As you know, loads of people start pred later. Currently I'm not taking pred after ovulation either!

If you're interested you could call the company to ask for sensitivity... I did that once lol. It took like 2 minutes! I think digital is 50 sensitivity?

sunnyday01 · 20/05/2015 18:29

I don't know! I dont use ov predictor kits and not doing SO meant I had no idea!

OP posts:
Hopender · 20/05/2015 18:13

Wow, sunny, so excited for you!! The supermarket ones always came up as faint for me too at the start and I'm now 30 weeks. How many days past ovulation are you?

sunnyday01 · 20/05/2015 18:09

Oh yes was on my vits but not pred for ov or aspirin, or my super ov drugs! It was a tesco own brand one - dudnt want to pay out when I thought it would be a bfn. I am worried it was feint though as May mean it's weak.

OP posts:
Drttc · 20/05/2015 18:04

Wow really interesting about the advice you got, Sunny. So no prenatals either? Good call staying on the hydroxy though! I've read it can take a longggg time before it's properly in your system so no point in stopping whatsoever.

Weird the digi came out but then the other was faint. Which brand was the faint one?

I think a while ago you had mentioned not being convinced your husband had low sperm count? I think this substantiates that!

sunnyday01 · 20/05/2015 17:58

Still can't believe it! I'm scared I have no symptoms and can't blame the pred!

OP posts:
sunnyday01 · 20/05/2015 17:57

Well after dh supposed low sperm result, Dr s advised that he needed to do a test in 2 months time after taking some tablets to see if it improves. He saud to stop all the drugs to give myself a break and also to concentrate on loosing weight and getting healthy etc. I decided to take hydroxy still as you have to take it for 6 weeks for it to be in your system do thought no point stopping as in 8 weeks they could say try again, then would need to wait another 6 weeks whilst I started taking it!

I'm on day 32, I did a test last week and it was negative, realised today that period was late but as had bo symptoms didn't think I was pregnant - did a test this morning but line was so feint I didn't know so did another digi test this afternoon and got pregnant 1-2!

OP posts:
Drttc · 20/05/2015 17:40

Updated :)

3rd Trimester
Hopender- (38 yrs old) 7 miscarriages, one DS, Was on pred, cycolgest, baby aspirin and intralipids. Now only baby aspirin! (29 wks)

1st trimester
Rosa (39yrs) - 3 MMC
(11.5, 6.5, 7.5). 6 months ttc on treatment. On complex programme for high NK, cytokines and thyroid antibodies (hydroxy, pred, intralipids)- had allergy to Humira. Also on SO programme. (10wks)

SeekingMiracles (30)
3mcs (5+3, 4+2 and blighted ovum 6+4). On treatment programme for high Nk cells and PT Gene variant. Pred, intralipds, fragments and aspirin. Currently crossing fingers and toes that this pregnancy works out. (7wks)

Sunnyday (32 yrs)- high nk cells - hydroxy, pred intralipids - 3 mc (1 on treatment) also doing super ovulation - round 1 (got bpf on round 5 last time) (4wks)

TTC

Tryingno1 (30 yrs old)- 3 mc. Ttc since April 2012. 5.5 weeks, 9 weeks, 6.5 weeks. High nk cells. Pred and intralipds. pa1 mutation. C4/m2 mutation. Hla dq match and low LAD. (Last ones done by ivf clinic) pred and intralipds. Along with asprin, clexane, metformin, hydroxy. discovered low sperm count. Starting first ivf injection in 1/2 weeks.

Hula2 (39 years) - one DS (took 18mns with low amh but no other probs), one MC at 9wks, ttc no 2 19 mns (12mns since last mc), low amh, borderline cytokines, high nks, on complex nk plan (pred, intralipids) about to do Humira for cytokines.

Drttc- (28 yrs old) 3 MCS (6 wks, 4wks 2 days, 5.5 weeks), very high NKC on complex treatment plan: hydroxy 2x day, 25 mg pred from ovulation, add cyclogest on bfp & Intralipids every 4 wks until 16 wks. Testing on May 28th.

lilliesandchocolate (32) 1 mc, 1dc, 5mc, 2nd dc on pred and cyclogest and the vitamins, 1mc. pred,cyclogest,intripalids and the vitamins.

WTTC

Determined123- awaiting (retest) results. 4mcs (2 on treatment). PCOS, Borderline NK Cells and v.high thyroid antibodies.