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Conception

When's the best time to get pregnant? Use our interactive ovulation calculator to work out when you're most fertile and most likely to conceive.

Immune/natural killer cell treatment when TTC or pregnant (aka the 14th pred thread)

993 replies

sunnyday01 · 29/11/2014 13:57

Continuing from 13th thread

OP posts:
Arianrhod · 05/12/2014 13:51

Should say .. free your advice about peppermint oil capsules really worked! thank you, I read about taking lactulose from the morning after CS (I couldn't face anything the same day) absolutely did the trick too, no problems in that dept! Still hurting 2.5 weeks on from the wound but that's to be expected I guess.

Arianrhod · 05/12/2014 13:48

cheerful Fab news, so pleased to see it! A can't believe your LO is 2 though, where on earth have the last 2 years gone. My Dad's birthday was 23rd Dec, he liked it. I'm still lurking here, just don't have much to post about now .. or brain power left to post! :)

freelancegirl · 04/12/2014 16:04

I haven't found out yet no, I was so tempted this time - even as far as we have it written in a sealed envelope from the 20w scan! But we haven't opened it so far. It's the sort of thing I would love to open if we had had a couple of glasses of wine and a lovely night out when on holiday...but that wasn't going to happen (although I have of course had the holidays just not enough wine :) ). You will let us know though when you know won't you!

Yes your last pregnancy sounds just like my last one which is the only I've ever managed to have tested and was indeed chromosomal. It's strangely comforting to know it's 'just one of those things'.

I too am the owner of one very lively toddler who doesn't like to sleep. So the next few months are going to be awful interesting.

Cheerfulcharlie · 04/12/2014 13:34

wow - twin boys! Have you found out your baby's gender yet Free? I had a Harmony type test the other day so will find out in a couple of weeks. Yes had the NT scan and looked good from there. Phew so far.
Yes I had another MC (on treatment) in Jan but it wasn't looking good from early on. By 7 weeks it was only measuring 6 weeks even though it had a heartbeat and it was all over by 8 weeks. I don't know for sure but I tend to think that one might have been a chromosomal one.
I will go ELCS this time too as advised by doc. 23rd Dec is a cool date to have for a birthday - what a perfect Christmas present. How on earth people cope with a toddler and a newborn I have no idea. My boy is rather lively to say the least so no idea how it works. Perhaps it's best just not to leave the house for 3 years....

freelancegirl · 04/12/2014 11:51

Charlie! Great to hear from you. I was only asking about you on here the other week as I thought you might be pregnant again. You had another miscarriage previously didn't you? So good to hear you're over the first trimester danger zone with this one! Have you had a scan?

Yep I'm 35 weeks and really feeling it. It's hard being pregnant and looking after a toddler as I am sure you are finding/will find! This Sunday I will take my last hydroxy, the final bit of medication for nkc. Hurrah! And I am booked in for another cs on 23rd December. Half can't wait until it's all over with but also terrified of a) anything going wrong and b) having two little ones to deal with!

Yes Ari has had her twin boys and all well (well, apart from never sleeping again etc etc...) and Duggs has also had her little boy very recently. Here's to more BFPs and babies soon!

Cheerfulcharlie · 04/12/2014 11:25

Hello! Some of you may remember me from the earlier threads ? I have a 2 year old that was the result of intralipid treatment after VHigh NKC diagnosis. I am now 12 weeks along with another, having had intralipids again since BFP.
Free - great to see you are 35 weeks along now! Has Ari had her twins yet?

dildoos · 03/12/2014 21:34

Sunny that's fab news Grin woohoo get going girl !!

How is everyone else today? X

Tryingno1 · 03/12/2014 20:48

That's great news sunny! I hope this is ur month :) .

Hope-how u holding up? Hope ur boobs are hurting and ur feeling sick! (In the nicest possible way! )

sunnyday01 · 03/12/2014 18:28

Well done for not using the ov sticks this month trying!

OP posts:
sunnyday01 · 03/12/2014 18:27

Scan was good - have 2 really good sized follicles! One is so big that louise think it might pop any second so has advised to DTD tonight just incase!! Lol!

Also got to do injection tonight but hasn't collected it from the chemist so had to drive 20 miles in the other direction to go and get it, so ovulation will be Friday and back on the pred from Friday too!

OP posts:
dildoos · 03/12/2014 15:38

Good luck to all ovulating! I agree hope I think we needs some bfp's for crimbo would be lovely and you ovulating ones are well times for that GrinWink

Hopender · 03/12/2014 14:10

Good luck Sunny, Trying, Mel, and Rosa too, I think! Hopefully this is the month. The law of averages makes me think there should be at least one other BFP before Christmas. Grin

Tryingno1 · 03/12/2014 13:53

Ps I kept to my word and am not doing ov sticks this month!

Tryingno1 · 03/12/2014 13:53

Good luck with ur scan sunny!
I'm ovulating in a few days too. Happy DTD to us both!
Have booked in for weekly acu this
Month...broken the bank balance. I hope it does something for me though!

sunnyday01 · 03/12/2014 10:46

HI everyone! Sorry I haven't been very active, work has been a bit manic over the past couple of weeks and I have been working long hours so not had much time for anything else!!

Need to catch up with all the other posts, but its ovulation time for me too this week - got my scan today to see how my follicles are doing - fingers crossed for some good eggs this month after i had to up my dose of the letrozole. This will be round 4 for me, so getting in to the time when most people who do SO get pregnant! I am having to get my scan done locally again as Mr s is away - would have liked to seen him as didn't see him last month and won't see him next month as my scan falls just after xmas so will have to go locally again. I am assuming i will ovulate at the weekend.

Hope everyone is ok!

OP posts:
dildoos · 02/12/2014 21:59

Just watching 17 kids and counting Sad feel so sad for her , I really don't think MC are any better with 0 child or 16 broke my heart to the family broken x

dildoos · 02/12/2014 21:42

Quite probable , I know prof q likes you to be 10 days past ovulation for a uterine scrap for nk cell level as she was our alternative however something about Mr s drew me to use him x

Tryingno1 · 02/12/2014 21:39

Yeah I think aggression / activity stays same...just levels vary. Mine were taken just as period ended! Wondering if my levels would have been high too if taken another time
Oh well I suppose I just wait and see if I get preg again Confused

dildoos · 02/12/2014 21:26

Yes NK cells can vary through out your cycle in how many I believe but the aggression I thought stayed the same and this was why for the pred? Arrrrggggghhhh so confusing! Xx

Tryingno1 · 02/12/2014 21:18

I see-is that what mr s said? I know free had sky high levels but always got preg v quickly...so maybe panic over nothing?
Like you dildoos, my nk cells are not high just active....but I also read levels can be lower if taken after ur
Period?!
Free ur an nk cell Expert- do u know anything that can be done naturally to bring them
Down? Or anyone else?

dildoos · 02/12/2014 21:13

Nk cells can stop you getting pregnant yes Sad
They vary in level inter uterine and in bloods.
Some people have normal levels of nk cells (me) but they are aggressive and fight things off (babies) so can get pregnant but then can't get past a certain few weeks due to the attack!
Does this help? We were advised against Ivf as he said this alone would not work xxx

Tryingno1 · 02/12/2014 20:40

Snoopy-good luck with him. And I hope ur next preg is succesful like ur mums :).

Girls I have a question/wondering u you have asked mr s...NK cells are also known to stop people getting preg/cause for failed ivf...are they a diff sub type (they all have diff markers) to the ones he tests for? Is NK cells stoping us getting preg something i should be worried about too?

freelancegirl · 02/12/2014 20:33

Glad to be of service! I have always tried to keep my TSH levels under 2 but as the years have gone by my thyroid must have gradually got worse as ive gone from needing an initial 50mcg thyroxine to now on 150. When I had my first two pregnancies I imagine my thyroid was out of kilter - the first being what might have kicked the thyroid problem off and the second I was probably under active without knowing it.

My third pregnancy was a horrible shock of a miscarriage at 12 weeks ( although had been a mmc at 8 weeks unbeknownst to myself) and at this point my thyroid was controlled. Fourth pregnancy was a blighted ovum (now on treatment with Mr S for hnk -thyroid controlled), fifth pregnancy was by DS - on all treatment, sixth saw a heartbeat at 7 weeks but it was gone by 8 weeks - turned out to be chromosomal and the only one I've managed to get tested, seventh pregnancy will hopefully be my second child in a few weeks time. All 5 most recent ones my thyroid has been well controlled and I have always found it ridiculously easy to get pregnant apart from this pregnancy now which took 4/5 months although I realise that's not so long.

There's no reason why your GP wouldn't test you for thyroid antibodies - ask for a full thyroid function test and spell it out to them - but I used to read horror stories about labs refusing to do these even when asked!

But yes mr Shehata is a miracle worker and understands thyroid issues fully. He will more than likely test your nk cells levels too. It might be a bit early on the day, as it were, to react after one miscarriage but if you can get the cash together and have such a strong family history of autoimmune conditions it could save you a lot of time and physical/mental challenges.

Mr S has always suggested waiting two cycles after a miscarriage. Not necessarily about dating but about making sure your body is ready. He is also likely to want you to be on pregnancy vitamins plus omega 3, extra vitamin d and low dose aspirin so it might be worth you starting these now. I also took selenium as that's something that can affect thyroid function and pregnancy and although it wasn't on his usual protocol he said go ahead.

dildoos · 02/12/2014 19:40

Evening all.

Mel so sorry to hear about your mum, how awful for you all. I wish her well for many many years to come and hope that the onset of Parkinson's is very very delayed!

Snoopy! Hi yes def the thread for you, some very knowledgable ladies here and always good for support and options/answers/ comparatives!

I saw dr shehata for the very first time on 29/10/14 was the best move forward for me for answers an a treatment plan!

I wish you well on your journey with him I think you will get some good answers for sure as he seems I me like he doesn't just 'give up' on us!

How is everyone today?

We have had some disgusting weather today I have to say winter has most definitely hit here! X

Snoopysimaginaryfriend · 02/12/2014 19:10

Tryingno1 that's ok! The appointment isn't until 19th January anyway.

It's difficult to know what to do.

Spookily the last six months of my life have completely mirrored my mums when she was 27, married in August, pregnant in September and a miscarriage in December. She was pregnant with me by New Years and didn't discover she had psoriatic arthritis until she was pregnant and got a new gp from Australia. Back then there weren't any treatments and she managed to have three healthy pregnancies and always got pregnant quickly. I'm hoping I will have some good reproductive genes to balance out my bad ones haha