I once taught an Effie - and yes I heard her get teased: Eff off, Effing hell, effie the heiffer.
But that is anecdotal and as a teacher I have come across hundreds of names - and I suppose they can all have something done to them as children are imaginative.
I don't like it, personally - the idea a name should be 'cute' or 'sweet' when it is one day going to belong to an adult woman. But, again, as a teacher, I have no doubt heard worse names.