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To think it will be revealed WLI cause physical aging

830 replies

Tuliptana · 02/03/2026 07:14

Obviously the pictures of Kelly Osbourne are both sad and terrifying.

But a few women i know have also used this method for weight loss and their skin has lost elasticity. They look at least 10 years older. Is this side effect being under played?

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18
Zanatdy · 04/03/2026 08:05

Notsosweetcaroline · 04/03/2026 07:40

Sure, but you were unwell. Being ill often ages people. It’s very different to eating a healthy diet in a defecit. The two are not comparable. Most people who lose weight due to illness will look aged.

I wasn’t unwell, I lost weight during Covid lockdown, not because of covid. When you’re in your 40-50’s even getting down to ideal weight can age you, it’s a fact. I look better in the face closer to 9 stone, but then I have excess weight on my stomach. Just a downside of losing weight later in life is it can age you.

likelysuspect · 04/03/2026 08:01

Nanda66 · 04/03/2026 06:44

I agree with you, although shapes and weights vary. I’ve lost over two stone and I’m now a size 14, a 16 in some things. But my BMI is now 28 so I’m no longer obese, just overweight. I actually look very slim. So at a size 14 I’m not obese but others will be. I’ll never be less than a 12/14.

In modern terms you look slim but at size 14/16 you're overweight as you say and wouldnt look slim if it was 50 or so years ago

Nothing wrong with that, Im about a stone more than I would like to be, just bordering on overweight and I look chubby but would be described by others as 'slim'. Im about a 12/14, the sizes mean nothing becuase I know my measurements are absolutely not a size 12 , more like a 16.

DarkForces · 04/03/2026 07:55

Dig, not 🐶 and I definitely look pretty damn good! I'm a bmi of 21.8 so perfectly healthy and my face looks younger than my years. People are shocked to find out I'm heading towards 50 and think I'm in my 30s

Nanda66 · 04/03/2026 07:51

Notsosweetcaroline · 04/03/2026 07:25

I have to agree with this, unless the poster is very tall indeed, and bmi would indicate not.

they likely feel the look very slim in comparison to before, but this is doubtful to be very slim in real terms. Very slim for me would be mid to lower point of a healthy bmi, few people look very slim when overweight and at a 14-16 dress size. Unless very muscular and then you’d not look very slim, you’d look muscular.

its funny how perception works. We see so many people lose a lot of weight and can’t see it, think they are still big, I myself gained a huge amount of weight with menopause as shown by the images above and I didn’t see it at all, I thought I looked like I always looked, I didn’t take pics like the one shown, and thought any candid shots from others or the ring doorbell wasn’t accurate. I couldn’t work out why my face looked fat in pics.

in fact my iPad has just show a memory which is a selfie from a couple of years ago and I’m really shocked at how fat my face was.

I do look slim. I don’t look thin, but I don’t look overweight in clothes. I have very broad shoulders and big boobs - even though I’ve lost a lot of weight I’m wearing the same cup size. I do have a bit of weight to lose on my tummy but have very slim arms and legs. I have good muscle tone. I don’t really want to upload a picture but I don’t look fat. I appreciate that I am though, but I carry it well.

BMI is a great indicator but it isn’t a one size fits all. I’d love to be a size 10 but it will never happen, I’m just not built like that. I’m aiming to get to the top end of healthy BMI for my height but definitely no lower. And at that weight I would expect to be size 14/16 on top and 12 on bottom.

Notsosweetcaroline · 04/03/2026 07:40

Zanatdy · 04/03/2026 07:38

I was still in a healthy weight for height, but it still aged me.

Sure, but you were unwell. Being ill often ages people. It’s very different to eating a healthy diet in a defecit. The two are not comparable. Most people who lose weight due to illness will look aged.

Zanatdy · 04/03/2026 07:38

Notsosweetcaroline · 04/03/2026 07:36

Absolutely, if someone goes under or over weight it is ageing.

the point being made is pretty much none of us are doing this. We are all predominantly staying a healthy weight.

I was still in a healthy weight for height, but it still aged me.

Notsosweetcaroline · 04/03/2026 07:36

Zanatdy · 04/03/2026 07:25

I lose 2stone in Covid and went to 7.5 stone and it aged me. So it’s not just WLI but i guess those on WLI will lose more and it can definitely lead to a gaunt look.

Absolutely, if someone goes under or over weight it is ageing.

the point being made is pretty much none of us are doing this. We are all predominantly staying a healthy weight.

EnterQueene · 04/03/2026 07:36

The before and after photos on this thread are an excellent example of how much better and healthier people look after losing significant amounts of weight. They are miles away from Kelly Osbourne, who really shouldn't be used to discourage women prioritising their health by losing weight.

I have been slim all my life and at nearly 60 I have wrinkles on my face - shock horror! Being a healthy weight will likely prolong your life - which is considerable more important than a few age appropriate wrinkles.

Zanatdy · 04/03/2026 07:25

I lose 2stone in Covid and went to 7.5 stone and it aged me. So it’s not just WLI but i guess those on WLI will lose more and it can definitely lead to a gaunt look.

Notsosweetcaroline · 04/03/2026 07:25

Helpiscoming · 04/03/2026 07:16

But if you're wearing a size 14, sometimes a size 16, then with respect that's not 'very slim'.
Thus proving my point; we all think of being bigger as normal now.

I have to agree with this, unless the poster is very tall indeed, and bmi would indicate not.

they likely feel the look very slim in comparison to before, but this is doubtful to be very slim in real terms. Very slim for me would be mid to lower point of a healthy bmi, few people look very slim when overweight and at a 14-16 dress size. Unless very muscular and then you’d not look very slim, you’d look muscular.

its funny how perception works. We see so many people lose a lot of weight and can’t see it, think they are still big, I myself gained a huge amount of weight with menopause as shown by the images above and I didn’t see it at all, I thought I looked like I always looked, I didn’t take pics like the one shown, and thought any candid shots from others or the ring doorbell wasn’t accurate. I couldn’t work out why my face looked fat in pics.

in fact my iPad has just show a memory which is a selfie from a couple of years ago and I’m really shocked at how fat my face was.

Helpiscoming · 04/03/2026 07:16

Nanda66 · 04/03/2026 06:44

I agree with you, although shapes and weights vary. I’ve lost over two stone and I’m now a size 14, a 16 in some things. But my BMI is now 28 so I’m no longer obese, just overweight. I actually look very slim. So at a size 14 I’m not obese but others will be. I’ll never be less than a 12/14.

But if you're wearing a size 14, sometimes a size 16, then with respect that's not 'very slim'.
Thus proving my point; we all think of being bigger as normal now.

Nanda66 · 04/03/2026 06:44

Helpiscoming · 04/03/2026 06:34

You say your friends had size 14/16 mum bods but were ''barely overweight let alone obese".
I had a size 14/16 mum body and at that dress size my weight put me in the BMI category of clinically obese.
I've lost 4 stone on MJ and I am still in the overweight BMI category. I need to lose another stone to reach BMI 25 and even then I'll still be in the top end of a healthy weight.
My point is, we have all become so accustomed to people being overweight we see size 14/16 as not particularly overweight anymore. But size 14/16 is overweight. I know it is, cos I was in BMI obese range at a size 14.

I agree with you, although shapes and weights vary. I’ve lost over two stone and I’m now a size 14, a 16 in some things. But my BMI is now 28 so I’m no longer obese, just overweight. I actually look very slim. So at a size 14 I’m not obese but others will be. I’ll never be less than a 12/14.

Helpiscoming · 04/03/2026 06:34

SuzyFandango · 02/03/2026 08:07

I don't really care about whoever Osborne.

I do care about my friends though....i live in a well off south east village, most of my friends (all in our forties) had size 14/16 "mum bods" and have eagerly found online pharmacies to give them mounjaro. One has yoyo-ed down to a size 6, stopped taking it, piled weight back on incredibly fast & is back on it. Another told me she had a horrendous run of stomach issues when taking it.

I do think at some point the supply to these people will be more strictly regulated, they were barely even overweight let alone obese so this is unlikely to be providing them with health benefits. The "checks" seem to be incredibly easy to lie to get around.

A friend is a doctor doing some specialist research into obesity and said that there are concerns around what WLI drugs do to your own endocrine function, with some people gaining weight more rapidly when they stop taking them. This would worry me a bit - sure you could stay on a "maintenence dose" forever but what will the pharma companies charge you for that?

You say your friends had size 14/16 mum bods but were ''barely overweight let alone obese".
I had a size 14/16 mum body and at that dress size my weight put me in the BMI category of clinically obese.
I've lost 4 stone on MJ and I am still in the overweight BMI category. I need to lose another stone to reach BMI 25 and even then I'll still be in the top end of a healthy weight.
My point is, we have all become so accustomed to people being overweight we see size 14/16 as not particularly overweight anymore. But size 14/16 is overweight. I know it is, cos I was in BMI obese range at a size 14.

Notsosweetcaroline · 04/03/2026 06:33

I can’t really comment to the voracity of the article in allure magazine you posted. I can though direct people to the trials on the medication,

here is the ai over view, anyone interested in the fact it is anti ageing can google based on the back of this and look at the multiple articles now on line from scientific bodies.

or maybe go with the plastic surgeon article in allure magazine..l

To think it will be revealed WLI cause physical aging
milkyuniverse · 04/03/2026 04:53

DarkForces · 03/03/2026 09:15

I can't find a single reference to back this up.

It was in an interview I saw in a longevity summit thing online, but did not purchase. He was talking about the differences in tissue of people of the same age, when he operated on them, and how you can feel the tissue - how well it integrates, how well it heals - and sometimes younger people had older internal tissues and vice versa; and that he had discussed with other surgeons their experience of tissue changes when operating on patients on GLP-1s.

Realistically, when you flood the body with a thousand-fold higher level of a manufactured substance than is naturally occuring, and one that stays in the body for days or weeks, rather than seconds or minutes, there will be some unexpected results.

catlover123456789 · 03/03/2026 23:08

People who are already skinny using wli to look like skeletons will look awful: Kelly Osborne looks seriously unwell and unrecognisable.

I take essential medications that have weight gaining side effects. I was getting to the point where walking just a short distance was painful.
I am now 19st 7lbs, lost about 2 stone so far. I can actually walk without pain now. WLI will almost certainly improve my life expectancy because it has allowed me to take tentative steps towards being more active again. I can see some features coming back in my previously round face, my clothes fit better, i feel more confident in myself. I definitely don't look older.

Notsosweetcaroline · 03/03/2026 21:30

Here are my before and after if people don’t want celebs , I’m also sure I look better and improved life expectancy and my blood rest results back that up, I also certainly don’t look older. My bmi is now 20 down from 32, lost 6 and a half stone, and maintained for a year now, dress size 8.

I was actually heavier at my start point than this I’d already been on a couple of months at the heavy picture, and I’m now leaner as I maintained my weight , but dropped a couple of percentage points in body fat, and built more muscle

im mid 50s, you can also probably tell from my swollen stomach I had a real cortisol problem due to menopause, which quickly resolved with the meds,

no one says I am too thin or skeletal.

To think it will be revealed WLI cause physical aging
To think it will be revealed WLI cause physical aging
Calliopespa · 03/03/2026 21:29

InfoSecInTheCity · 03/03/2026 21:19

I was 19 stone (now 9st 12lb) and size 22/24 (now size 10/12). When I was 10/11 years old the kids started calling me piggy, or the Fat Controller. I have literally had men in white vans shouting “fat cunt” at me as I walk down the street, teenagers in the park laughing and shouting fat jokes as I passed them by, men in bars/clubs grabbing my belly or boobs on a night out and mocking me. People are horrible to women who dare to be overweight in their presence.

There are people at work who I’ve worked alongside for a decade who are suddenly nice to me, listen to me and ask me to be involved in their projects. The only thing that’s changed is the size of my trousers and how much I hate them. They disgust me, shallow, judgemental, pathetic worms.

My friend has suffered similar. It has actually mostly been her MIL. I'm sorry for what you went through and it does disgust me too. It is part of the reason the whole "thin above all and at any cost" rhetoric bothers me though, and at a different end of the scale I do think the WLI are enabling a resurgence of these unhealthy values. I know someone who died of anorexia. She just got so small it wasn't tenable. Both these friends are/were the loveliest people and so much more than their weight.

You look lovely now: please stop!!

InfoSecInTheCity · 03/03/2026 21:19

Calliopespa · 03/03/2026 21:04

That is a definite change, and I can see you would look quite different to your friends.

I completely agree with your first paragraph about different cases and starts and end points - and fwiw I don't think your end point looks unhealthy at all. You look very healthy now, and I'm pleased for the change for you if you have suffered abuse. But the abuse does surprise me: lots of people look like that! I can see you would have been obese in that before photo but were you really BMI 38?

I was 19 stone (now 9st 12lb) and size 22/24 (now size 10/12). When I was 10/11 years old the kids started calling me piggy, or the Fat Controller. I have literally had men in white vans shouting “fat cunt” at me as I walk down the street, teenagers in the park laughing and shouting fat jokes as I passed them by, men in bars/clubs grabbing my belly or boobs on a night out and mocking me. People are horrible to women who dare to be overweight in their presence.

There are people at work who I’ve worked alongside for a decade who are suddenly nice to me, listen to me and ask me to be involved in their projects. The only thing that’s changed is the size of my trousers and how much I hate them. They disgust me, shallow, judgemental, pathetic worms.

FurForksSake · 03/03/2026 21:14

This was my start and end (ish, I am probably 5lbs under this now). BMI 32 to 21/22.

To think it will be revealed WLI cause physical aging
To think it will be revealed WLI cause physical aging
Calliopespa · 03/03/2026 21:11

LaurieFairyCake · 03/03/2026 20:08

massive transformation! Well done you Infosec FlowersFlowersFlowers

And @TheBroonOneAndTheWhiteOne !

Calliopespa · 03/03/2026 21:07

These are great photos to see because the results DO look healthy!

Calliopespa · 03/03/2026 21:06

TheBroonOneAndTheWhiteOne · 03/03/2026 20:35

Here are my Before and After pictures.
I actually gained another two stone prior to starting on WLI, so that photo isn't me at my heaviest.

I've lost 9st 8lb.

My BMI was over 50 when I started on MJ two years ago. It's now just under 26. According to the BMI scale I'm still overweight, even though my clothes are all size 8 and size 10.

I'm 69 years old. I'm quite sure that I've markedly improved my life expectancy because of MJ.

Edited

That's a big change!!