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To think it will be revealed WLI cause physical aging

830 replies

Tuliptana · 02/03/2026 07:14

Obviously the pictures of Kelly Osbourne are both sad and terrifying.

But a few women i know have also used this method for weight loss and their skin has lost elasticity. They look at least 10 years older. Is this side effect being under played?

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18
KimberleyClark · 04/03/2026 11:39

Re exercise, it’s known that the health benefits of moderate exercise over no exercise are far greater than the benefits of intense exercise over moderate exercise.

HeadDeskHeadDesk · 04/03/2026 10:58

Stopping the jab does usually lead to weight regain. As does traditional dieting. There's only one thing shown to successfully address existing obesity, and that's sustained WLI use. This obviously comes with risks, but so does being obese. Being obese and losing weight are both risks for gallbladder problems!

Agree. HRT raises the risk of breast cancer but most of us are prepared to take that risk on the chin given that our lives can be immeasurably improved by HRT. Statins are not without risk or side effects. Neither is chemotherapy. Sometimes the chemo will kill us before the cancer does. Every drug given to solve one issue carries a heightened risk of something else. Name me one that doesn't. It's a trade off. Always has been, always will be.

Exercising vigorously and taking part in sports heightens the risk of breaking bones, having accidents, needing joint replacements, rotator cuff problems, sometimes arthritis, reptitive strain injury, or simply dropping dead of a heart attack because in spite of appearing ostensibly fit and healthy, the extreme exersion highlighted a heart defect you didn't know you had, and might never have really troubled you if only you hadn't run that marathon.

But people are encouraged to do exercise and play sport because it's good for you in all sorts of ways, social, mental and physical that are deemed to outweigh those risks.

Binus · 04/03/2026 10:52

likelysuspect · 04/03/2026 10:46

A friend of mine falls into the obese category, she is simply a stone more than me and Im a few lbs into the overweight category. Its as small as that, or as big as that however people want to see it

And absolutely the WLI 'cures' the reason for being overweight, which is overeating. We are designed to seek out high calorie foods as a species, its why we are still here, our bodies are designed to survive, like any animal. You dont see cats, dogs, bears, tigers picking away at nibbles, they eat high calorie dense food, they seek it out. They'll eat too much of it given the chance.

Thread after thread you get the pearl clutchers and po faced self righteous going on about 'deep seated issues' and 'therapy'. Most people become overweight through habit, ease of consumption, society and culture. The UK (or US/Australia) doesnt have any more 'deep seated' issues around food than other countries which have less obesity, what we have is a food culture that leads to overeating and plentiful opportunity. Simple as that.

And honestly, obesity is on the rise in nearly all developed countries. Even Japan. The only one that's managed to curb it recently is the US.

There aren't actually any examples of human societies that didn't hadn't develop an obesity problem once they had enough resources to provide the whole population with more calories than they need and also didn't have loads of the population on appetite suppressant drugs. It just happens sooner in some than others.

likelysuspect · 04/03/2026 10:46

Binus · 04/03/2026 10:35

Actually, the weight loss jab does very much solve the reason the person was overweight in the first place for many of us. That is, eating more than we burned off. Which isn't something that needs pathologising or can be cured, because it's a normal human behaviour.

Stopping the jab does usually lead to weight regain. As does traditional dieting. There's only one thing shown to successfully address existing obesity, and that's sustained WLI use. This obviously comes with risks, but so does being obese. Being obese and losing weight are both risks for gallbladder problems!

Lastly, I dont think 'not terribly overweight' is a very helpful description. People can be clearly obese, with all the risks that entails, and not be perceived as such by those around them.

A friend of mine falls into the obese category, she is simply a stone more than me and Im a few lbs into the overweight category. Its as small as that, or as big as that however people want to see it

And absolutely the WLI 'cures' the reason for being overweight, which is overeating. We are designed to seek out high calorie foods as a species, its why we are still here, our bodies are designed to survive, like any animal. You dont see cats, dogs, bears, tigers picking away at nibbles, they eat high calorie dense food, they seek it out. They'll eat too much of it given the chance.

Thread after thread you get the pearl clutchers and po faced self righteous going on about 'deep seated issues' and 'therapy'. Most people become overweight through habit, ease of consumption, society and culture. The UK (or US/Australia) doesnt have any more 'deep seated' issues around food than other countries which have less obesity, what we have is a food culture that leads to overeating and plentiful opportunity. Simple as that.

Binus · 04/03/2026 10:35

Forestgreenblue · 04/03/2026 09:13

I think it’s great that a lot of people who were significantly overweight and unable to lose weight before have managed on the jab. Loose skin is purely from rapid weight loss and loss of collagen.

However the weight loss jab ultimately doesn’t magically solve the reason they were overweight in the first place and if they don’t work on their own eating habits and healthy habits I would imagine stopping the jab would cause weight regain. It is also not without its risks.

Personally we have had 2 people in our family who have been on them - one ended up in hospital and had her gall bladder removed - now will have life long issues as a result - and one hid her symptoms of dreadful gastro issues and significant pain for months before stopping, though she was happy with the results of her weight loss, she actually looked really poorly a lot of the time and had the reported ‘ozempic face’. She was actually grey at one point. We were terribly worried about her as she wasn’t actually particularly overweight to begin with. She’s regained most of her weight though since stopping.

Long term I would be concerned about premature loss of bone density, particularly where the weight loss jab is being used by people who don’t medically qualify for it OR are using it when they are already underweight - Kelly Obsourne for example. In females this is something we will naturally decline with in age so early progression is a huge concern.

Id imagine with the majority of people who are getting their jabs from unregulated suppliers that their bone density isn’t being checked or tracked in any way.

Whilst people say, quite rightly, it’s a medication that has been utilised by diabetics for years so their assumption is that it’s completely safe - well an diabetics other option of not using it is frankly death. The jabs are a medication with risks associated to it, no matter which way you look at it.

Actually, the weight loss jab does very much solve the reason the person was overweight in the first place for many of us. That is, eating more than we burned off. Which isn't something that needs pathologising or can be cured, because it's a normal human behaviour.

Stopping the jab does usually lead to weight regain. As does traditional dieting. There's only one thing shown to successfully address existing obesity, and that's sustained WLI use. This obviously comes with risks, but so does being obese. Being obese and losing weight are both risks for gallbladder problems!

Lastly, I dont think 'not terribly overweight' is a very helpful description. People can be clearly obese, with all the risks that entails, and not be perceived as such by those around them.

likelysuspect · 04/03/2026 10:32

The biggest comorbidity for gall stones and gall bladder problems is obesity

Fat, fair, female, fertile (semi myth)

Bearsdolovetrees · 04/03/2026 10:31

Imdunfer · 03/03/2026 09:18

You didn't look very far, this took me one search to find.

pmc.ncbi.nlm.nih.gov/articles/PMC10213739/

That’s a letter to an editor from a random chinese scientist not a peer reviewed paper. Also, it says there have been no such effects observed in humans. Quite clearly. The effects mentioned were in rats given HUGE amounts of the drug. If you’re going to post ‘scientific evidence’ please at least read and understand it.

brunettemic · 04/03/2026 10:25

I don’t think it will be revealed, it’s pretty obvious. The question of whether or not it’s a bad thing is then down to the individual. Health wise it’s arguably a non issue.

ruethewhirl · 04/03/2026 10:21

gostickyourheadinapig · 02/03/2026 08:51

Nobody ever died of looking a bit older, but many have died from complications of obesity.

Exactly this.

SherbetDipDap · 04/03/2026 10:19

God fat women can’t win, can they?

If they’re fat, they’re disgusting and unhealthy.

If they loose weight they’re haggard, old crones who have ‘cheated’ to loose weight.

A lot of thin women have a massive superiority complex.

Forestgreenblue · 04/03/2026 10:11

Nanda66 · 04/03/2026 09:54

The experience of your family members isn’t representative of most users. The person who suffered terrible gastric issues should have either stopped taking the jab or reduced the dose. They certainly should have sought medical advice. It’s irresponsible use of prescription medication like this that lead to people saying that the jabs are bad for you.

Personally I’ve had no side effect since the first couple of jabs, I am eating healthily and normally, ensuring I eat adequate amounts of protein and exercising regularly. I’ve only increased the dose when I felt I need to. I’ve lost weight very slowly and I feel fantastic. That’s my experience, and you’ll find it’s the experience of many many people.

I didn’t say our experiences with family members is representative of most users though did I. I simply pointed out what we had experienced. I’m sure a lot of people, like yourself, have no issues however the fact remains that a lot of people do have issues. I’ve also said it’s not a bad thing - I’m sure for a lot of people it’s been an absolute game changer for them.

And yes I agree that my family member should have stopped the jabs when they were experiencing pain - but how many people out there are also experiencing pain but loving their weight loss? I’m sure there are people out there who are choosing to continue their weight loss rather than listen to their body.

Nanda66 · 04/03/2026 09:54

Forestgreenblue · 04/03/2026 09:13

I think it’s great that a lot of people who were significantly overweight and unable to lose weight before have managed on the jab. Loose skin is purely from rapid weight loss and loss of collagen.

However the weight loss jab ultimately doesn’t magically solve the reason they were overweight in the first place and if they don’t work on their own eating habits and healthy habits I would imagine stopping the jab would cause weight regain. It is also not without its risks.

Personally we have had 2 people in our family who have been on them - one ended up in hospital and had her gall bladder removed - now will have life long issues as a result - and one hid her symptoms of dreadful gastro issues and significant pain for months before stopping, though she was happy with the results of her weight loss, she actually looked really poorly a lot of the time and had the reported ‘ozempic face’. She was actually grey at one point. We were terribly worried about her as she wasn’t actually particularly overweight to begin with. She’s regained most of her weight though since stopping.

Long term I would be concerned about premature loss of bone density, particularly where the weight loss jab is being used by people who don’t medically qualify for it OR are using it when they are already underweight - Kelly Obsourne for example. In females this is something we will naturally decline with in age so early progression is a huge concern.

Id imagine with the majority of people who are getting their jabs from unregulated suppliers that their bone density isn’t being checked or tracked in any way.

Whilst people say, quite rightly, it’s a medication that has been utilised by diabetics for years so their assumption is that it’s completely safe - well an diabetics other option of not using it is frankly death. The jabs are a medication with risks associated to it, no matter which way you look at it.

The experience of your family members isn’t representative of most users. The person who suffered terrible gastric issues should have either stopped taking the jab or reduced the dose. They certainly should have sought medical advice. It’s irresponsible use of prescription medication like this that lead to people saying that the jabs are bad for you.

Personally I’ve had no side effect since the first couple of jabs, I am eating healthily and normally, ensuring I eat adequate amounts of protein and exercising regularly. I’ve only increased the dose when I felt I need to. I’ve lost weight very slowly and I feel fantastic. That’s my experience, and you’ll find it’s the experience of many many people.

Forestgreenblue · 04/03/2026 09:53

Mrsredlipstick · 04/03/2026 09:32

@Forestgreenblue I only took the jab for three weeks and ended up in hospital. I've had my gallbladder removed as I had gallstones. I didn't know but they had showed up two years prior to taking the jab. The weren't cause by it and at that point I was six stone heavier.
I was in agony. However the wli side effect saved my life as it was discovered I had a more serious illness. Had I not been blue lighted I would have died.
Thanks wegovy.

Obviously I couldn't continue with the jab but I've had no issues with my gut since.

They showed up 2 years prior though ?

I believe if they are unsymptomatic and at a size where they can possibly pass naturally then they are left in situ - however as you said you ended up being blue lighted to hospital and I am presuming in pain (so now symptomatic after weeks of using the jabs) leading to you having your gall bladder removed. I’d hardly say this is a good result of taking the jab.

On a further note gall bladder removal surgery is massively increased in the NHS at the moment because of the suspected link of the jab - which is reported and being reviewed on.

Mrsredlipstick · 04/03/2026 09:32

@Forestgreenblue I only took the jab for three weeks and ended up in hospital. I've had my gallbladder removed as I had gallstones. I didn't know but they had showed up two years prior to taking the jab. The weren't cause by it and at that point I was six stone heavier.
I was in agony. However the wli side effect saved my life as it was discovered I had a more serious illness. Had I not been blue lighted I would have died.
Thanks wegovy.

Obviously I couldn't continue with the jab but I've had no issues with my gut since.

Forestgreenblue · 04/03/2026 09:13

I think it’s great that a lot of people who were significantly overweight and unable to lose weight before have managed on the jab. Loose skin is purely from rapid weight loss and loss of collagen.

However the weight loss jab ultimately doesn’t magically solve the reason they were overweight in the first place and if they don’t work on their own eating habits and healthy habits I would imagine stopping the jab would cause weight regain. It is also not without its risks.

Personally we have had 2 people in our family who have been on them - one ended up in hospital and had her gall bladder removed - now will have life long issues as a result - and one hid her symptoms of dreadful gastro issues and significant pain for months before stopping, though she was happy with the results of her weight loss, she actually looked really poorly a lot of the time and had the reported ‘ozempic face’. She was actually grey at one point. We were terribly worried about her as she wasn’t actually particularly overweight to begin with. She’s regained most of her weight though since stopping.

Long term I would be concerned about premature loss of bone density, particularly where the weight loss jab is being used by people who don’t medically qualify for it OR are using it when they are already underweight - Kelly Obsourne for example. In females this is something we will naturally decline with in age so early progression is a huge concern.

Id imagine with the majority of people who are getting their jabs from unregulated suppliers that their bone density isn’t being checked or tracked in any way.

Whilst people say, quite rightly, it’s a medication that has been utilised by diabetics for years so their assumption is that it’s completely safe - well an diabetics other option of not using it is frankly death. The jabs are a medication with risks associated to it, no matter which way you look at it.

Notsosweetcaroline · 04/03/2026 08:44

likelysuspect · 04/03/2026 08:36

Well you'll notice I was careful not to use the words 'it has aged me'

My weight loss hasnt aged me at all, Ive probably added years to my life, maybe decades, who knows, or to a healthy life I should say

But I do look older, those two things are different

Me personally I have tons of of loose skin, I spent nearly 50 years overweight, had no skin elasticity before weight loss and none now, I had lots and lots of stretch marks. That sort of skin is never going to adjust, it is what it is. I have always had very thin skin

I look great in clothese, I wont wear a bikini (never have anyway!), but thats not what I did it for.

So yes, loose skin is abundant but Im not that bothered.

And I think that’s valid. And I also think you raise a good point. On skin health and how long over weight.

i was overweight for less than 5 years, menopause did for me, and of course I didn’t gain it over night, it was a slow progression up. So I don’t have lose skin when I hit goal. Being overweight for a few years will have a very different result to being overweight for 50.

I also worked out throughout, ate my protein, drank my collagen, did a mix of strength and cardio exercises 5-6 days a week, still do, protected my muscle, and moisturised all over daily, as the moisture and the massage motion helps skin.

so some people will have loose skin, it will be unavoidable. Others will not, and many factors will play into what you end up with when you hit goal.

but you’re right, you will have added years to your life, and your internal organs will very likely be less aged, and much more healthy.

i think nearly all of us doing this legitimately do this for health first and foremost. I was becoming really quite ill, with very high blood pressure and sleep apnea. It was difficult to function if I’m honest, as I was exhausted all the time.

likelysuspect · 04/03/2026 08:36

Notsosweetcaroline · 04/03/2026 08:27

Agree, it’s odd, I’m mid fifties, I posted my before and afters up thread, I lost six and a half stone, and it is clearly visible I have absolutely no loose skin. Anywhere.

I had some crepy skin on my upper arms, but it disappeared totally. My face is the same, i have no jowls,marionette lines, saggy neck etc, just forehead wrinkles and crows feet which are normal.

so I just don’t get it I don’t see this ageing thing some folks go on about. On none of the before and afters.

What I do see is people irrelevant of weight, gain, loss stability, that age better than others, or worse than others, often due to diet, genetics, lifestyle etc. but that’s nothing to do with the drugs or losing weight, it would always happen to them. And yes maybe being heavier does help their faces, but in no way can that be used as a generalisation.

Well you'll notice I was careful not to use the words 'it has aged me'

My weight loss hasnt aged me at all, Ive probably added years to my life, maybe decades, who knows, or to a healthy life I should say

But I do look older, those two things are different

Me personally I have tons of of loose skin, I spent nearly 50 years overweight, had no skin elasticity before weight loss and none now, I had lots and lots of stretch marks. That sort of skin is never going to adjust, it is what it is. I have always had very thin skin

I look great in clothese, I wont wear a bikini (never have anyway!), but thats not what I did it for.

So yes, loose skin is abundant but Im not that bothered.

HeidiLite · 04/03/2026 08:34

I don't want to trot out the 'we have lost sight what healthy weight looks like' but it's true. Size 16 woman is not 'barely overweight', never mind slim. But many studies have shown that people tend to misjudge their own weight when their social circle is heavier. So if an average woman is 16 then yes it's understandable that overweight seems average. And not big. And size 14 may seem slim in comparison, as it's smaller than average.
Medically not accurate though.

I am now often called too slim, too thin - my BMI is 20.8, could happily lose another 6-7 kilos to get close to underweight and too thin. But I do of course look slim compared to an average person - because 'average' is objectively overweight.

Nanda66 · 04/03/2026 08:30

likelysuspect · 04/03/2026 08:19

BMI has such a wide range its ridiculous to dismiss it and say 'one size doesnt fit all'. Of course it doesnt, thats why each BMI range has about 3 stone variance in it and is different for different ethnicities.

I’m not dismissing it, I appreciate it’s a broad range. I will definitely be at or near the top of it. I suspect even happy to be just above it. I think what I was trying to say is that people have a perception of what, for example, a size 14 looks like and weighs. But the reality is that it is very different for different people. At size 14 I look slim (I know I’m still overweight). Others will look fat at size 14. I’ll never be a 10, it’s not possible.

Notsosweetcaroline · 04/03/2026 08:27

likelysuspect · 04/03/2026 08:11

Yes I dont think its outrageous or verboten to say that sometimes people look older if they lose weight. Ive lost half my body weight, I do look older, but then Im in peri and the aging started before my weight loss, my face sort of half fell off its self, and then Iost weight so that continued the journey.

I now look my age whereas before I probably looked younger than my age.

My health has benefited hugely though so Im not bothered and most people will look younger as extra weight is aging.

The two things that people go on about hugely is loose skin and aging. The two worst things that can happen to a person apparently 'oh what are you going to do about the loose skin, you'll get loads of loose skin', as if its preferable to be 10 stone overweight rather than have loose skin. Or god forbid a woman looks older, the worst female crime ever

Perhaps if we werent obsessed with these things we could focus on the health benefits of being a healthy weight, give or take a few pounds.

Agree, it’s odd, I’m mid fifties, I posted my before and afters up thread, I lost six and a half stone, and it is clearly visible I have absolutely no loose skin. Anywhere.

I had some crepy skin on my upper arms, but it disappeared totally. My face is the same, i have no jowls,marionette lines, saggy neck etc, just forehead wrinkles and crows feet which are normal.

so I just don’t get it I don’t see this ageing thing some folks go on about. On none of the before and afters.

What I do see is people irrelevant of weight, gain, loss stability, that age better than others, or worse than others, often due to diet, genetics, lifestyle etc. but that’s nothing to do with the drugs or losing weight, it would always happen to them. And yes maybe being heavier does help their faces, but in no way can that be used as a generalisation.

Notsosweetcaroline · 04/03/2026 08:21

The thing people are missing gaining weight also ages you. A healthy bmi is best; yes some folks will be unfortunate in terms of genetics, and have saggy faces and wrinkles, genetics and previous life style. But that’s just life. It is not everyone is, in fact go on any before and after view, most on Reddit show their faces and you can see people looo more youthful.

likelysuspect · 04/03/2026 08:19

BMI has such a wide range its ridiculous to dismiss it and say 'one size doesnt fit all'. Of course it doesnt, thats why each BMI range has about 3 stone variance in it and is different for different ethnicities.

EnterQueene · 04/03/2026 08:16

To be clear - losing weight hasn't aged you. You make think you look older, but that is a different thing. Losing weight will likely prolong your life, so it could be said to have youthed you, more than aged you. Which I think is more important that the relentless focus on looks over health.

CreamolaFoam26 · 04/03/2026 08:13

BMI is a great indicator but it isn’t a one size fits all

Im not a fan of BMI at all but I do like to refer to ‘smart bmi’. In fact I knew I’d never want to be even at the top of my regular BMI but when I found the smart BMI I was really happy to find that what I’d instinctively known was a great weight for me was actually what turned out to be my smart bmi.

eta - what numbers make me happy? It’s very easy. It’s the numbers I now see on my absolutely fantastic blood test results.

likelysuspect · 04/03/2026 08:11

Yes I dont think its outrageous or verboten to say that sometimes people look older if they lose weight. Ive lost half my body weight, I do look older, but then Im in peri and the aging started before my weight loss, my face sort of half fell off its self, and then Iost weight so that continued the journey.

I now look my age whereas before I probably looked younger than my age.

My health has benefited hugely though so Im not bothered and most people will look younger as extra weight is aging.

The two things that people go on about hugely is loose skin and aging. The two worst things that can happen to a person apparently 'oh what are you going to do about the loose skin, you'll get loads of loose skin', as if its preferable to be 10 stone overweight rather than have loose skin. Or god forbid a woman looks older, the worst female crime ever

Perhaps if we werent obsessed with these things we could focus on the health benefits of being a healthy weight, give or take a few pounds.