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AIBU?

Share your dilemmas and get honest opinions from other Mumsnetters.

to feel uneasy about what this means long term rather than surprised by the weight regain itself?

682 replies

HazelMember · 28/01/2026 18:03

I’ve just read a BBC article about research into weight loss injections like Ozempic and Wegovy showing that people who stop taking them tend to regain weight quite quickly.

I’m not shocked that weight comes back. That happens after most weight loss attempts whether they involve medication or not.

These drugs are increasingly talked about as something people might take for years or even indefinitely. That raises questions for me about what happens when someone cannot afford them anymore, when supply changes, when side effects become an issue or when a person simply does not want to stay on a medication for life.

If stopping leads not just to regain but to a fairly rapid rebound, it feels less like a temporary aid and more like something that is very hard to step away from once started. That sits oddly with how casually they are sometimes discussed.

AIBU to think the real issue here is not that people regain weight after stopping, but whether we are quietly normalising a treatment that may be difficult to discontinue once begun? Or is this simply the reality of managing a chronic condition?

A woman, wearing bright red nail polish and unbuttoned blue jeans, injects herself into the skin and soft tissue of her lower abdomen with an obesity jab pen.

People coming off weight-loss injections risk fast weight gain

Overweight people shed large amounts on jabs but gain 0.8 kg a month on average once off them, study shows.

https://www.bbc.co.uk/news/articles/c050ljnrv2qo

OP posts:
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14
Binus · 01/02/2026 14:05

Tonissister · 01/02/2026 12:46

Come on. The massive difference here is - you don't have to pay for statins. A huge number of people who benefit from WLI have to pay for them privately. It's hard to keep that up. A better rquation would be ADHD drugs. People can get along with out them, just as people can exist without WLI but life and health are better with them, and yet they are not considered of primary importance to health.

Incientally - I would say that about statins. They are not necessarily viable long term. After a year or so they can cause awful side effects, including deep bone aches. I know a lot of people who have come off them because the side effects caused them to need strong painkillers. A lot of people take NHS funded drugs to ward off the side effects of other NHS funded drugs. In the end, the benefits of statins are not always valuable enough to offset the side effects.

I didn't know that about statins, thanks for the information. Makes me even gladder that WLIs have reduced my risk of needing them!

soupyspoon · 01/02/2026 13:44

Theres no cure for human nature

Fat people have always existed and do exist throughout the world at different levels and for different social and cultural reasons. Obesity lives with us, and always will.

If WLI are bad because of the natural limitations of payment, having to remain on them, industrial waste, skinny people using them, well so be it. So what.

Binus · 01/02/2026 13:39

HazelMember · 01/02/2026 12:10

I agree. There is little incentive to “cure” obesity. Managing it indefinitely is far more convenient and far more profitable for the pharmaceutical companies.

What sort of cure do you think might work? This is important, because all of our failed attempts to curb obesity thus far have hugely enriched pharmaceutical countries, what with them not working.

HazelMember · 01/02/2026 13:05

Tonissister · 01/02/2026 12:46

Come on. The massive difference here is - you don't have to pay for statins. A huge number of people who benefit from WLI have to pay for them privately. It's hard to keep that up. A better rquation would be ADHD drugs. People can get along with out them, just as people can exist without WLI but life and health are better with them, and yet they are not considered of primary importance to health.

Incientally - I would say that about statins. They are not necessarily viable long term. After a year or so they can cause awful side effects, including deep bone aches. I know a lot of people who have come off them because the side effects caused them to need strong painkillers. A lot of people take NHS funded drugs to ward off the side effects of other NHS funded drugs. In the end, the benefits of statins are not always valuable enough to offset the side effects.

Agree.

There’s a lot of whataboutery in this thread. Every time WLIs are mentioned, someone jumps in with “well what about this other drug?” or “what about that medication?”.

This thread is about WLIs. Not every medication that’s ever existed. Different meds do different things, come with different risk and are prescribed for different reasons.

OP posts:
Tonissister · 01/02/2026 12:46

SaintAgatha · 28/01/2026 18:19

If you took a brief stroll through historical posts, there are many posters like you expressing wide-eyed concern about the implications of life on a WLI. Do you feel the same disquiet about statins?

Come on. The massive difference here is - you don't have to pay for statins. A huge number of people who benefit from WLI have to pay for them privately. It's hard to keep that up. A better rquation would be ADHD drugs. People can get along with out them, just as people can exist without WLI but life and health are better with them, and yet they are not considered of primary importance to health.

Incientally - I would say that about statins. They are not necessarily viable long term. After a year or so they can cause awful side effects, including deep bone aches. I know a lot of people who have come off them because the side effects caused them to need strong painkillers. A lot of people take NHS funded drugs to ward off the side effects of other NHS funded drugs. In the end, the benefits of statins are not always valuable enough to offset the side effects.

RufustheFactuaIReindeer · 01/02/2026 12:26

It is fascinating though about how people react

yes…agreed

RufustheFactuaIReindeer · 01/02/2026 12:24

It assumes that choosing WLI automatically means someone has fully thought everything through and that anyone asking questions must be judging or criticising

nope…

I used the word most…not all

i used the word some repeatedly which means ‘not all’

i also used a real life example of people i know being genuinely curious…..so loads of people not being judgy at all

youve completely turned my post around to mean the opposite of what I said

Wickedlittledancer · 01/02/2026 12:21

HazelMember · 01/02/2026 12:10

I agree. There is little incentive to “cure” obesity. Managing it indefinitely is far more convenient and far more profitable for the pharmaceutical companies.

But they are curing it, they are now working on a once and done injection.its called gene therapy, and they are also working on a monthly one. So once again you’re talking nonsense.

HazelMember · 01/02/2026 12:10

Bruisername · 28/01/2026 18:42

I agree OP. I think they are great for tackling obesity but long term use of any drug should be avoided if at all possible and with obesity it’s important to tackle the underlying causes (societal I mean - as a pp said - pushing unhealthy foods alongside the WLI isn’t great!). Or even therapy if over eating is a trauma response.

of course the pharmaceutical companies have an incentive to keep people on them for life so why would anyone address the underlying causes of obesity

I agree. There is little incentive to “cure” obesity. Managing it indefinitely is far more convenient and far more profitable for the pharmaceutical companies.

OP posts:
SwingTheMonkey · 01/02/2026 11:56

I mean, it is entirely possible to leave your own thread. If you realise you’ve been a bit of a dick and people have seen through your ‘concerned’ act…

HazelMember · 01/02/2026 11:53

velvetgeranium · 01/02/2026 11:41

Yes! And apparently you should leave your own thread!

That really made me laugh 😂

OP posts:
soupyspoon · 01/02/2026 11:52

I mean this thread has not been started in good faith at all. Im amazed its still standing.

Alltheyellowbirds · 01/02/2026 11:49

velvetgeranium · 01/02/2026 11:41

Yes! And apparently you should leave your own thread!

I think you’ve got that backwards. It’s OP repeatedly telling people to leave the thread.

velvetgeranium · 01/02/2026 11:41

HazelMember · 01/02/2026 11:34

Flew off the handle? 😂

Yes! And apparently you should leave your own thread!

Wickedlittledancer · 01/02/2026 11:38

HazelMember · 01/02/2026 11:34

Flew off the handle? 😂

It’s as comical as you telling people to leave the thread as they are upset or triggered.

honestly you keep dishing it out but clearly hate it coming back to you.

Alltheyellowbirds · 01/02/2026 11:37

HazelMember · 01/02/2026 11:34

Flew off the handle? 😂

Telling people to leave the thread does come off as flying off the handle yes. Or at least as having a strop.

Alltheyellowbirds · 01/02/2026 11:36

HazelMember · 01/02/2026 10:54

I’m not telling people they have to agree with me. I’m saying that if someone is getting worked up or clearly unhappy with the direction of the discussion, they’re not obliged to stay.

Starting a thread doesn’t require expert status. People start threads all the time for various reasons.

I didn’t say you can’t start a thread on something you’re not an expert about 🙄 I said that it’s weird to ask a question about something you don’t know about and then not be interested in answers from people with experience and knowledge of it.

See the rock-climbing example I used. If I started a thread because I was “concerned” that people were putting their lives in danger going climbing, or “concerned” that it’s an expensive hobby they might not be able to afford, I’d be specifically looking to hear from the people who actually go rock climbing.

You on the other hand have ignored or disparaged every answer from people who know anything about WLI, posted negative link after negative link, and repeatedly challenged anyone who disagrees with your narrative to report the thread and leave.

That is what people are taking issue with.

HazelMember · 01/02/2026 11:34

Flew off the handle? 😂

OP posts:
Wickedlittledancer · 01/02/2026 11:07

HazelMember · 01/02/2026 10:23

People can post on whatever angle they wish to. They do not have to follow guidance from other posters. If people are getting so worked up then leave the thread.

Simple.

It is fascinating though about how people react.

Op why did you ask, I specifically responded to your post , with a valid come back and you immediately flew off the handle, once again telling people to leave the thread.

stop giving it if you cannot cope with anyone coming back at you. You also don’t need to stay on the thread if it’s upsetting you.

soupyspoon · 01/02/2026 10:59

HazelMember · 01/02/2026 10:54

I’m not telling people they have to agree with me. I’m saying that if someone is getting worked up or clearly unhappy with the direction of the discussion, they’re not obliged to stay.

Starting a thread doesn’t require expert status. People start threads all the time for various reasons.

Its clear you are very unhappy with the direction of discussion

You highlight things to express your unease or concern and dont like the correction of that

So the drugs create industrial waste, just like any other drug and not as much as other drugs as per the list I put forward. No comment about that?

So the drugs stop working when you stop taking them, no shit. Just like all the other medications there are. No comment about that?

So you say the drugs make weight gain 4x more likely than other slimming methods but the research isnt on real life cases and doesnt take account of the amount lost over all which is much more than other slimming methods, no comment about that?

So the drugs can be misused, just like any drugs particularly the opioid painkiller drugs around, no comment about that?

So what is the discussion about exactly? Whats your point?

Binus · 01/02/2026 10:56

OP what would you say your level of knowledge about obesity and WLIs was, before starting the thread? I can see that you don't feel you're an expert, which I agree isn't a necessity to start an MN thread.

HazelMember · 01/02/2026 10:54

I’m not telling people they have to agree with me. I’m saying that if someone is getting worked up or clearly unhappy with the direction of the discussion, they’re not obliged to stay.

Starting a thread doesn’t require expert status. People start threads all the time for various reasons.

OP posts:
Alltheyellowbirds · 01/02/2026 10:38

HazelMember · 01/02/2026 10:23

People can post on whatever angle they wish to. They do not have to follow guidance from other posters. If people are getting so worked up then leave the thread.

Simple.

It is fascinating though about how people react.

What’s fascinating is you repeatedly instructing other people to leave the thread. It’s almost as if you don’t want anyone in the conversation who doesn’t agree with you.

It’s also fascinating that you would start a thread on a subject you know nothing about and then not want to hear from the people who do. If I started a thread about say, the dangers of rock climbing, I would specifically be wanting to learn from the people who do it and therefore have knowledge of the subject.

HazelMember · 01/02/2026 10:23

People can post on whatever angle they wish to. They do not have to follow guidance from other posters. If people are getting so worked up then leave the thread.

Simple.

It is fascinating though about how people react.

OP posts:
Wickedlittledancer · 01/02/2026 10:16

HazelMember · 01/02/2026 10:10

I don’t really agree with this. It assumes that choosing WLI automatically means someone has fully thought everything through and that anyone asking questions must be judging or criticising. That just isn’t always the case. People ask questions for lots of reasons. It does not mean they think someone is lazy or greedy.

I also think there is a tendency to read bad intent into any questioning at all. Not every “have you thought about X” is an attack. If every question is treated as judgement, then no one can say anything.

I get that it must be tiring to feel like you are constantly having to justify yourself. But feeling worn down does not automatically make the discussions unreasonable and it does not mean going on the attack is the only understandable response.

People can post a thread for whatever reasons they want, they do not need to have an objective, they do not reveal anything about themselves. Even if it has been posted thousands of times, they can post again if they want. As long as they are not breaking the talk guidelines of course.

The poster said most users, not all. And I agree with them looking at threads on here and Reddit, people are very well educated and more than able to make decisions on their health. Most does not mean all.

and people take into based on posts made, an example would be everything you posted was negative, at no stage did you look to balance it with the positives. So people can assume you were simply wishing to be negative about the meds for your own reasons.

had you posted about the health benefits, the societal benefits, the environmental impacts of all the meds and treatments people needed due to obesity and offset it with the tiny environmental impact of the wli, your arguments would have appeared balanced.

but yoh didn’t,