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AIBU?

Share your dilemmas and get honest opinions from other Mumsnetters.

to feel uneasy about what this means long term rather than surprised by the weight regain itself?

682 replies

HazelMember · 28/01/2026 18:03

I’ve just read a BBC article about research into weight loss injections like Ozempic and Wegovy showing that people who stop taking them tend to regain weight quite quickly.

I’m not shocked that weight comes back. That happens after most weight loss attempts whether they involve medication or not.

These drugs are increasingly talked about as something people might take for years or even indefinitely. That raises questions for me about what happens when someone cannot afford them anymore, when supply changes, when side effects become an issue or when a person simply does not want to stay on a medication for life.

If stopping leads not just to regain but to a fairly rapid rebound, it feels less like a temporary aid and more like something that is very hard to step away from once started. That sits oddly with how casually they are sometimes discussed.

AIBU to think the real issue here is not that people regain weight after stopping, but whether we are quietly normalising a treatment that may be difficult to discontinue once begun? Or is this simply the reality of managing a chronic condition?

A woman, wearing bright red nail polish and unbuttoned blue jeans, injects herself into the skin and soft tissue of her lower abdomen with an obesity jab pen.

People coming off weight-loss injections risk fast weight gain

Overweight people shed large amounts on jabs but gain 0.8 kg a month on average once off them, study shows.

https://www.bbc.co.uk/news/articles/c050ljnrv2qo

OP posts:
Thread gallery
14
Bloozie · 02/02/2026 13:32

velvetgeranium · 02/02/2026 12:35

What is all this objection to the very existance of this thread if not ownership of some drug? What is all the mockery of posters wanting to discuss the topic of thread, if not a weird ownership of some GLP-1 drug of one brand or another the objectors all happen to be on?

You and many others like you only want to discuss the topic of the thread so you can use it as a vehicle for your uninformed views on the moral depravity of fat people while signalling the twin virtues of denial and restraint, in full denial of the body of research into the causes of obesity and all tied up in a disingenuous 'I'm just interested in the medicines people take can't we even TALK about this' bow.

And it's this disingenuousness that people taking WLI are reacting strongly to. No one wants to take ownership of anything. They're just a little bored of the pious hand-wringing and pearl clutching, and the faux concern. If you and others like you genuinely cared about obese people, you'd take a step back and think more carefully about how you frame your arguments.

I feel like the best course of action for you, personally, would be to not take a GLP-1 drug. But you need to reach your own decision on that. And trust other people to do the same.

Binus · 02/02/2026 13:23

velvetgeranium · 02/02/2026 13:09

When 90% of a 600+-post thread is posters defending themselves against a small group of people determined to shut down, derail, and end a topic discussion - because they don't like any criticism of a substance they are injecting - then I call that taking ownership.

Even in this post, you declare it off limits for the OP and others to discuss the issue - as if she has no right to. That is taking ownership. If you are so full of knowledge of the topic, enough to declare who is and isn't allowed to discuss it, why aren't you responding to the question of the PP who wants to know what will happen when she goes off WLI?

More projection! I'm not saying the OPs stance is the only way of taking ownership. The exact opposite, in fact. It's one of multiple ways.

You also need to get better at reading if you think trying to invite someone into discussion, as I have with OP, is declaring it off limits to her. I am again doing the precise opposite.

velvetgeranium · 02/02/2026 13:09

Binus · 02/02/2026 13:00

You wrote 'The only posters showing ownership of the topic are the ones who insist it must not be discussed'. The idea that only one group can be taking ownership of an issue came from you, not me. You're projecting that onto me. Don't.

My point is about the OP and similar as a group who feel enough ownership to discuss the issue without having any idea what they're talking about. So for example OPs post yesterday about cures and incentives is interesting because she had enough of an opinion to type that, whilst also showing no indication of having engaged with any evidence on the issue (same is also true of the person she was agreeing with). This is distinct from someone who feels ownership of an issue because of their relevant personal or professional experience.

I did ask OP to expand further on that point yesterday, hoping for a meatier discussion of her points than she's yet offered, but didn't get a response.

When 90% of a 600+-post thread is posters defending themselves against a small group of people determined to shut down, derail, and end a topic discussion - because they don't like any criticism of a substance they are injecting - then I call that taking ownership.

Even in this post, you declare it off limits for the OP and others to discuss the issue - as if she has no right to. That is taking ownership. If you are so full of knowledge of the topic, enough to declare who is and isn't allowed to discuss it, why aren't you responding to the question of the PP who wants to know what will happen when she goes off WLI?

Binus · 02/02/2026 13:00

velvetgeranium · 02/02/2026 12:35

What is all this objection to the very existance of this thread if not ownership of some drug? What is all the mockery of posters wanting to discuss the topic of thread, if not a weird ownership of some GLP-1 drug of one brand or another the objectors all happen to be on?

You wrote 'The only posters showing ownership of the topic are the ones who insist it must not be discussed'. The idea that only one group can be taking ownership of an issue came from you, not me. You're projecting that onto me. Don't.

My point is about the OP and similar as a group who feel enough ownership to discuss the issue without having any idea what they're talking about. So for example OPs post yesterday about cures and incentives is interesting because she had enough of an opinion to type that, whilst also showing no indication of having engaged with any evidence on the issue (same is also true of the person she was agreeing with). This is distinct from someone who feels ownership of an issue because of their relevant personal or professional experience.

I did ask OP to expand further on that point yesterday, hoping for a meatier discussion of her points than she's yet offered, but didn't get a response.

Worralorra · 02/02/2026 12:37

I’ve been on the WLI (Wegovy) for a few months. One thing I haven’t experienced (yet) is feeling ill when I eat too much, so I have been waiting for the moment when I feel “just” full, and stop eating there.
I have also been observing the reduction in portion sizes that correlate to me feeling full, and have been reducing the size of my portions accordingly.
The intention is to reach my target weight, then stay on the same portion size to see if I lose or gain weight, adjusting as necessary.
Are you saying that without the WLI, and even with the reduced portion sizes (i .e. the magical “Lifestyle Change” that is discussed very widely), I would gain weight?

velvetgeranium · 02/02/2026 12:35

Binus · 02/02/2026 12:22

You can't really be accusing anyone of projection and then type that second sentence with a straight face!

What is all this objection to the very existance of this thread if not ownership of some drug? What is all the mockery of posters wanting to discuss the topic of thread, if not a weird ownership of some GLP-1 drug of one brand or another the objectors all happen to be on?

Binus · 02/02/2026 12:22

velvetgeranium · 02/02/2026 12:16

It's the projection. It's mindboggling. The only posters showing ownership of the topic are the ones who insist it must not be discussed.

You can't really be accusing anyone of projection and then type that second sentence with a straight face!

velvetgeranium · 02/02/2026 12:16

Binus · 02/02/2026 11:07

What, is he involved as well now?

It's the projection. It's mindboggling. The only posters showing ownership of the topic are the ones who insist it must not be discussed.

soupyspoon · 02/02/2026 11:31

Binus · 02/02/2026 11:07

What, is he involved as well now?

Well he did turn water into that well known, 'wonder drug' - wine.

Good on him

People were up in arms with their concerns of course. He was a very naughty boy.

Binus · 02/02/2026 11:07

velvetgeranium · 02/02/2026 11:01

It's pretty obvious why someone like OP feels the level of familiarity and ownership over the issue that she clearly does

Jesus Christ.

What, is he involved as well now?

velvetgeranium · 02/02/2026 11:01

It's pretty obvious why someone like OP feels the level of familiarity and ownership over the issue that she clearly does

Jesus Christ.

velvetgeranium · 02/02/2026 10:52

SwingTheMonkey · 02/02/2026 09:07

No, it’s because nobody cares about medications other people are taking, unless it’s related to weight loss.

No, it's because it is a new and hugely popular weight loss "wonder drug". There hasn't been a huge new popular weight loss wonder drug since the 90s.

I care about what medications other people are taking. I find it interesting.

Binus · 02/02/2026 09:52

If we're honest with ourselves, it's worth acknowledging that WLI medication doesn't just relate to health but also allows people to access something that has previously had rarity as well as social value. There aren't really comparable examples of other medicines.

To that end, it would be surprising if it didn't elicit a different set of responses to other medications. People's pile cream and inhalers don't have anything like the same wider importance, because we don't attach social significance to them like we do to body size and shape. It's pretty obvious why someone like OP feels the level of familiarity and ownership over the issue that she clearly does, and it's broadly the same thing that led the BBC to pick that headline. She has plenty of company.

And I actually think all this is only to be expected.

SwingTheMonkey · 02/02/2026 09:07

velvetgeranium · 02/02/2026 08:13

Well, it might be because statins have been on the market since the 90s and the longterm and adverse effects and most downsides are now well known.

Nobody is trying to source statins on the black market, or shooting themselves up with compounds made in some suburban kitchen or garage that they bought online. And people who don't actually need statins are not trying to find loopholes to secure them.

Also, the law suits have mostly been settled (17 million dollar payout from Pfizer and Ranbaxy); unlike the currently pending lawsuits around GLP-1s, expected to cost manufacturers around 2 billion dollars.

But I do still look forward to reading an interesting thread talking about statins. Or paracetamol.

Edited

No, it’s because nobody cares about medications other people are taking, unless it’s related to weight loss.

velvetgeranium · 02/02/2026 08:13

SwingTheMonkey · 02/02/2026 05:22

It’d be a very quiet thread, I imagine, because unlike weight loss medication, nobody gives a fuck about statins. I wonder why that might be?

Well, it might be because statins have been on the market since the 90s and the longterm and adverse effects and most downsides are now well known.

Nobody is trying to source statins on the black market, or shooting themselves up with compounds made in some suburban kitchen or garage that they bought online. And people who don't actually need statins are not trying to find loopholes to secure them.

Also, the law suits have mostly been settled (17 million dollar payout from Pfizer and Ranbaxy); unlike the currently pending lawsuits around GLP-1s, expected to cost manufacturers around 2 billion dollars.

But I do still look forward to reading an interesting thread talking about statins. Or paracetamol.

Wickedlittledancer · 02/02/2026 07:23

Binus · 02/02/2026 07:19

You won't be able to recreate the stylistic effect OP has managed to achieve here either, sadly. It's a type of insouciance only really available to people who don't know what they don't know. The energy OP has exuded in this thread isn't great for looking like you know what you're talking about, but it is does motivate people to engage. But it's not available to everyone, you have to be authentically not very well informed!

Suspect she maybe also authentically uninformed on statins, but I too look forward to that thread,where she informs all the statin users how uneasy she feels about their medication.

😄

Binus · 02/02/2026 07:19

SwingTheMonkey · 02/02/2026 05:22

It’d be a very quiet thread, I imagine, because unlike weight loss medication, nobody gives a fuck about statins. I wonder why that might be?

You won't be able to recreate the stylistic effect OP has managed to achieve here either, sadly. It's a type of insouciance only really available to people who don't know what they don't know. The energy OP has exuded in this thread isn't great for looking like you know what you're talking about, but it is does motivate people to engage. But it's not available to everyone, you have to be authentically not very well informed!

SwingTheMonkey · 02/02/2026 05:22

velvetgeranium · 01/02/2026 22:28

I am looking forward to your statin thread! I am sure you will be able to discuss the adverse effects of statins and what happens when you do stop taking them, and are there any lifestyle changes you have made that work as well - without a group leaping on to ask in querulous tones, "Why are you so concerned about statins? You're just jealous and bitter because I have statins!"

It’d be a very quiet thread, I imagine, because unlike weight loss medication, nobody gives a fuck about statins. I wonder why that might be?

HazelMember · 01/02/2026 22:39

velvetgeranium · 01/02/2026 22:28

I am looking forward to your statin thread! I am sure you will be able to discuss the adverse effects of statins and what happens when you do stop taking them, and are there any lifestyle changes you have made that work as well - without a group leaping on to ask in querulous tones, "Why are you so concerned about statins? You're just jealous and bitter because I have statins!"

Love your use of the word querulous. It is absolutely spot on!

OP posts:
velvetgeranium · 01/02/2026 22:28

I am looking forward to your statin thread! I am sure you will be able to discuss the adverse effects of statins and what happens when you do stop taking them, and are there any lifestyle changes you have made that work as well - without a group leaping on to ask in querulous tones, "Why are you so concerned about statins? You're just jealous and bitter because I have statins!"

RufustheFactuaIReindeer · 01/02/2026 18:34

Deffo agree

godmum56 · 01/02/2026 18:33

godmum56 · 01/02/2026 18:13

My late husband did, my late mother didn't. Both on the same statin.

at least now GP's accept that it happens!

RufustheFactuaIReindeer · 01/02/2026 18:19

godmum

yeah its funny how the same thing can affect someone differently

godmum56 · 01/02/2026 18:13

RufustheFactuaIReindeer · 01/02/2026 14:07

I am on statins…glad I don’t have those side effects!!!

My late husband did, my late mother didn't. Both on the same statin.

RufustheFactuaIReindeer · 01/02/2026 14:07

I am on statins…glad I don’t have those side effects!!!