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AIBU?

Share your dilemmas and get honest opinions from other Mumsnetters.

to feel uneasy about what this means long term rather than surprised by the weight regain itself?

682 replies

HazelMember · 28/01/2026 18:03

I’ve just read a BBC article about research into weight loss injections like Ozempic and Wegovy showing that people who stop taking them tend to regain weight quite quickly.

I’m not shocked that weight comes back. That happens after most weight loss attempts whether they involve medication or not.

These drugs are increasingly talked about as something people might take for years or even indefinitely. That raises questions for me about what happens when someone cannot afford them anymore, when supply changes, when side effects become an issue or when a person simply does not want to stay on a medication for life.

If stopping leads not just to regain but to a fairly rapid rebound, it feels less like a temporary aid and more like something that is very hard to step away from once started. That sits oddly with how casually they are sometimes discussed.

AIBU to think the real issue here is not that people regain weight after stopping, but whether we are quietly normalising a treatment that may be difficult to discontinue once begun? Or is this simply the reality of managing a chronic condition?

A woman, wearing bright red nail polish and unbuttoned blue jeans, injects herself into the skin and soft tissue of her lower abdomen with an obesity jab pen.

People coming off weight-loss injections risk fast weight gain

Overweight people shed large amounts on jabs but gain 0.8 kg a month on average once off them, study shows.

https://www.bbc.co.uk/news/articles/c050ljnrv2qo

OP posts:
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HeidiLite · 28/01/2026 18:12

other sources have found many people will keep weight off successfully. But yes, many need to keep taking the wli just like any other medication to treat a chronic condition. I'm not stopping thyroid meds just because my levels at the moment are normal.

https://www.reuters.com/business/healthcare-pharmaceuticals/many-patients-may-keep-off-lost-pounds-after-stopping-glp-1-us-data-suggests-2026-01-22/

SaintAgatha · 28/01/2026 18:10

MrsMiagi · 28/01/2026 18:07

Some conditions may require lifelong medication. Obesity is one of the conditions. However, because its obesity, the idea of this seems odd to people.
Are you considering wli yourself op?

Exactly this. Another faux concern post because people can’t stand the fatties being thin. Find your social capital elsewhere, would be my advice.

waitingforthehallmarkedman · 28/01/2026 18:10

Disturbia81 · 28/01/2026 18:08

I think most will need to be on them for life. Because there’s a reason most needed them in the first place. Hopefully a pill will come along and it will keep improving with less side effects.

Eli lilly are working on a mounjaro pill!

blubberball · 28/01/2026 18:08

I'd love to be on wli. The cost and side effects put me off

Disturbia81 · 28/01/2026 18:08

I think most will need to be on them for life. Because there’s a reason most needed them in the first place. Hopefully a pill will come along and it will keep improving with less side effects.

MrsMiagi · 28/01/2026 18:07

Some conditions may require lifelong medication. Obesity is one of the conditions. However, because its obesity, the idea of this seems odd to people.
Are you considering wli yourself op?

Jackiepumpkinhead · 28/01/2026 18:05

Another WLI bashing thread, what fun. I’ll get my bingo card ready.