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AIBU?

Share your dilemmas and get honest opinions from other Mumsnetters.

to feel uneasy about what this means long term rather than surprised by the weight regain itself?

682 replies

HazelMember · 28/01/2026 18:03

I’ve just read a BBC article about research into weight loss injections like Ozempic and Wegovy showing that people who stop taking them tend to regain weight quite quickly.

I’m not shocked that weight comes back. That happens after most weight loss attempts whether they involve medication or not.

These drugs are increasingly talked about as something people might take for years or even indefinitely. That raises questions for me about what happens when someone cannot afford them anymore, when supply changes, when side effects become an issue or when a person simply does not want to stay on a medication for life.

If stopping leads not just to regain but to a fairly rapid rebound, it feels less like a temporary aid and more like something that is very hard to step away from once started. That sits oddly with how casually they are sometimes discussed.

AIBU to think the real issue here is not that people regain weight after stopping, but whether we are quietly normalising a treatment that may be difficult to discontinue once begun? Or is this simply the reality of managing a chronic condition?

A woman, wearing bright red nail polish and unbuttoned blue jeans, injects herself into the skin and soft tissue of her lower abdomen with an obesity jab pen.

People coming off weight-loss injections risk fast weight gain

Overweight people shed large amounts on jabs but gain 0.8 kg a month on average once off them, study shows.

https://www.bbc.co.uk/news/articles/c050ljnrv2qo

OP posts:
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14
MagpiePi · 28/01/2026 18:40

Gingercar · 28/01/2026 18:15

I think it’s incredibly naive to think that you’re going to stroll off into the sunset without working very hard to maintain a weight loss. I’m on WLI and hope to drop them at the end. Most of my “naturally slim” friends work very hard at staying slim. I want to be like them - keeping an eye on my weight and reining myself in if need be. I definitely don’t want to stay on the drugs, despite having had no side effects whatsoever. I was obese, I’m not any longer. I was prediabetic, I’m not any more. I had high blood pressure and cholesterol, I don’t any more. I hope I can do it myself. I’ve been able to eat pretty normally on WLI l, I didn’t get full and had “food noise” so I hope I got used to using willpower and eating sensibly as much as the drugs.

You’d probably count me as ‘naturally thin’ but like your friends, it takes a lot of hard work to stay this way. From what I’ve heard other people say, I have all the food noise going on, but cope by having quite a restrictive and controlled diet and some pretty unhealthy attitudes to food, exercise and myself.
If they are now saying that people could stay on WLIs for life once they’d reached a healthy weight, why can’t people like me take them? I’d love to take a drug that stopped the constant battle that’s going on in my head.

soupyspoon · 28/01/2026 18:35

CraftyMintHedgehog · 28/01/2026 18:22

I disagree.

This is a HUGE issue. It is a drug that needs to be taken continuously otherwise you lose all benefits. For those who might struggle with money, or have a change in financial circumstances, or the price of the drug goes up, then they have no choice but to stop.

But ultimately, people already know this so need to make sure they have the financial means to continue or accept that they will have to find a more sustainable way to lose weight.

The drug is made by Novo Nordisk, so what's to stop them suddenly pushing the price up? I mean, it would make them a LOT of money now all these people are so reliant on it. They have HUGE pricing power here.

This is how a lot of successful diet things work. Herbalife is the same - it's a starvation diet that is only sustainable if you keep paying the exorbitant prices for their shakes. As soon as you stop, the weight goes back on. And the people selling this stuff are making a HUGE amount of money from it, and throw huge party conferences to celebrate!

So YABU to accuse people of starting a bashing thread when this could become a huge headache for many people trying to lose weight.

Which is why it should be available on the NHS

This worry about unsustainable 'treatment' applies to lots of things that many of us have to purchase or source privately because the NHS doesnt supply it or wont do it in a timely way. See therapy as another example.

Turmerictea · 28/01/2026 18:31

I took the tablet form for 3 months and lost two stone. Ive regained about 8lbs albeit very slowly. I thought Id go back on the pills and four days in, I got pancreatitis. So I can never take the meds again.

Back to faux keto and working out for me!

SaintAgatha · 28/01/2026 18:31

HazelMember · 28/01/2026 18:22

Does this mean I have a problem with fatties being thin? To quote the language of the pp.

I think you’re being disingenuous. And you didn’t answer my question about statins.

MO0N · 28/01/2026 18:28

Ihateboris · 28/01/2026 18:27

Pharmaceutical companies are basically legal drug dealers. THEY WANT you to get addicted.

Of course, they want a guaranteed income stream to protect profits & keep jobs.

Gwenhwyfar · 28/01/2026 18:28

HazelMember · 28/01/2026 18:15

It would make sense for them to be more widely available as it would be cheaper for the NHS in the long run.

I would think that they will be more easily available on the NHS in future.

Ihateboris · 28/01/2026 18:27

Happygirl79 · 28/01/2026 18:24

You are absolutely spot on

Pharmaceutical companies are basically legal drug dealers. THEY WANT you to get addicted.

Gwenhwyfar · 28/01/2026 18:26

"That raises questions for me about what happens when someone cannot afford them anymore, when supply changes, when side effects become an issue or when a person simply does not want to stay on a medication for life."

And also about how they are not available to normal weight people with small amounts to lose or maintain, but previously overweight/obese people can take them even while at a healthy weight.

Happygirl79 · 28/01/2026 18:24

MO0N · 28/01/2026 18:13

You're looking at it all wrong OP!
It's about making money for the big corporations.
Fast food companies produce HIFLs (highly addictive food-like substances) many people cant resist them and become overweight.
Pharmaceutical companies have found a solution but it only works while you are using it. When you stop you cant resist the lure of the HIFLs, so they get your money for a while. Then you go back on the jabs and the pharma companies get your money, until you get fed up of the side effects and go back on the HIFLs.
Etc.

You are absolutely spot on

QuickBlueKoala · 28/01/2026 18:23

Weight loss only works if you change your lifestyle. Weightloss drugs are no different, so no surprises here?

CraftyMintHedgehog · 28/01/2026 18:22

Jackiepumpkinhead · 28/01/2026 18:05

Another WLI bashing thread, what fun. I’ll get my bingo card ready.

I disagree.

This is a HUGE issue. It is a drug that needs to be taken continuously otherwise you lose all benefits. For those who might struggle with money, or have a change in financial circumstances, or the price of the drug goes up, then they have no choice but to stop.

But ultimately, people already know this so need to make sure they have the financial means to continue or accept that they will have to find a more sustainable way to lose weight.

The drug is made by Novo Nordisk, so what's to stop them suddenly pushing the price up? I mean, it would make them a LOT of money now all these people are so reliant on it. They have HUGE pricing power here.

This is how a lot of successful diet things work. Herbalife is the same - it's a starvation diet that is only sustainable if you keep paying the exorbitant prices for their shakes. As soon as you stop, the weight goes back on. And the people selling this stuff are making a HUGE amount of money from it, and throw huge party conferences to celebrate!

So YABU to accuse people of starting a bashing thread when this could become a huge headache for many people trying to lose weight.

HazelMember · 28/01/2026 18:22

SaintAgatha · 28/01/2026 18:19

If you took a brief stroll through historical posts, there are many posters like you expressing wide-eyed concern about the implications of life on a WLI. Do you feel the same disquiet about statins?

Does this mean I have a problem with fatties being thin? To quote the language of the pp.

OP posts:
TempNameForObviousReasons · 28/01/2026 18:20

These WLI are going to come back and bite everyone on the backside in a few years.

SaintAgatha · 28/01/2026 18:19

HazelMember · 28/01/2026 18:14

Where did I say I had a a problem with fatties being thin? If they are now thin then they are not fatties anymore surely? (to use your language).

If you took a brief stroll through historical posts, there are many posters like you expressing wide-eyed concern about the implications of life on a WLI. Do you feel the same disquiet about statins?

HazelMember · 28/01/2026 18:19

houseofisms · 28/01/2026 18:18

I think the problem is that when you’re on it, I suppresses your appetite and people think they’ve got used to smaller portions so will be fine once stopped. Appetite soon comes back when you finish them. (I’ve used the jabs for a few months but stopped as the side effects)

What side effects did you have?

OP posts:
houseofisms · 28/01/2026 18:18

I think the problem is that when you’re on it, I suppresses your appetite and people think they’ve got used to smaller portions so will be fine once stopped. Appetite soon comes back when you finish them. (I’ve used the jabs for a few months but stopped as the side effects)

LookingThroughGlass · 28/01/2026 18:17

That raises questions for me about what happens when someone cannot afford them anymore, when supply changes, when side effects become an issue or when a person simply does not want to stay on a medication for life.

They have the choice to maintain the eating habits they've adopted on WLI - it may be hard but no harder than starting a diet from a position of being obese.

Disturbia81 · 28/01/2026 18:15

waitingforthehallmarkedman · 28/01/2026 18:10

Eli lilly are working on a mounjaro pill!

That’s great news

Gingercar · 28/01/2026 18:15

I think it’s incredibly naive to think that you’re going to stroll off into the sunset without working very hard to maintain a weight loss. I’m on WLI and hope to drop them at the end. Most of my “naturally slim” friends work very hard at staying slim. I want to be like them - keeping an eye on my weight and reining myself in if need be. I definitely don’t want to stay on the drugs, despite having had no side effects whatsoever. I was obese, I’m not any longer. I was prediabetic, I’m not any more. I had high blood pressure and cholesterol, I don’t any more. I hope I can do it myself. I’ve been able to eat pretty normally on WLI l, I didn’t get full and had “food noise” so I hope I got used to using willpower and eating sensibly as much as the drugs.

HazelMember · 28/01/2026 18:15

WallaceinAnderland · 28/01/2026 18:13

It doesn't seem fair that they are only available to people who can afford them, but that's life I guess. Yet another privilege for the rich who can afford to buy them for life.

It would make sense for them to be more widely available as it would be cheaper for the NHS in the long run.

OP posts:
Nickyknackered · 28/01/2026 18:14

@HazelMember how long have you been on WLI so far OP?

HazelMember · 28/01/2026 18:14

SaintAgatha · 28/01/2026 18:10

Exactly this. Another faux concern post because people can’t stand the fatties being thin. Find your social capital elsewhere, would be my advice.

Where did I say I had a a problem with fatties being thin? If they are now thin then they are not fatties anymore surely? (to use your language).

OP posts:
MO0N · 28/01/2026 18:13

You're looking at it all wrong OP!
It's about making money for the big corporations.
Fast food companies produce HIFLs (highly addictive food-like substances) many people cant resist them and become overweight.
Pharmaceutical companies have found a solution but it only works while you are using it. When you stop you cant resist the lure of the HIFLs, so they get your money for a while. Then you go back on the jabs and the pharma companies get your money, until you get fed up of the side effects and go back on the HIFLs.
Etc.

WallaceinAnderland · 28/01/2026 18:13

It doesn't seem fair that they are only available to people who can afford them, but that's life I guess. Yet another privilege for the rich who can afford to buy them for life.

Knitterofcrap · 28/01/2026 18:12

Lots of medications for lifelong health conditions can be withdrawn for various reasons, or patients can develop unacceptable side effects. WLI are no different in this respect.

There are new medications being developed and trialled at the moment which might be cheaper, might minimise side effects for those who suffer.

I can’t imagine not taking epilepsy/asthma medication because I might have to stop taking it for any reason.