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AIBU?

Share your dilemmas and get honest opinions from other Mumsnetters.

to feel uneasy about what this means long term rather than surprised by the weight regain itself?

682 replies

HazelMember · 28/01/2026 18:03

I’ve just read a BBC article about research into weight loss injections like Ozempic and Wegovy showing that people who stop taking them tend to regain weight quite quickly.

I’m not shocked that weight comes back. That happens after most weight loss attempts whether they involve medication or not.

These drugs are increasingly talked about as something people might take for years or even indefinitely. That raises questions for me about what happens when someone cannot afford them anymore, when supply changes, when side effects become an issue or when a person simply does not want to stay on a medication for life.

If stopping leads not just to regain but to a fairly rapid rebound, it feels less like a temporary aid and more like something that is very hard to step away from once started. That sits oddly with how casually they are sometimes discussed.

AIBU to think the real issue here is not that people regain weight after stopping, but whether we are quietly normalising a treatment that may be difficult to discontinue once begun? Or is this simply the reality of managing a chronic condition?

A woman, wearing bright red nail polish and unbuttoned blue jeans, injects herself into the skin and soft tissue of her lower abdomen with an obesity jab pen.

People coming off weight-loss injections risk fast weight gain

Overweight people shed large amounts on jabs but gain 0.8 kg a month on average once off them, study shows.

https://www.bbc.co.uk/news/articles/c050ljnrv2qo

OP posts:
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Happyjoe · 28/01/2026 21:26

I saw the same news article OP, was a few weeks ago. Something that the weight goes back on 8 times as fast as someone coming off a normal diet.

I do feel as if the drug has been a little miss-sold to people and it's now coming to light. That this will have to be a long term thing if people are unable to keep up the good work after the medicine has stopped. I am a little concerned about long-term side effects, are they as serious as obesity, or are we swapping one set of health problems for another? And does the risk go up with age like most things do? Are people able to keep taking it into their 60/70's?

As it stands, they are helping people massively, making drugs companies rich and saving (hopefully) the NHS money in lack of obesity-related illnesses. I do wonder about the long term and it feels a little like the general public are being used as an experiment and things will be learned down the line as they come to light, much like HRT did.

Binus · 28/01/2026 21:26

Whataninterestinglookingpotato · 28/01/2026 21:21

of course you can live a lifestyle that reduces your risk of cancer but many many cancers will strike for no real reason.

very few people are obese because of health conditions. Mostly it’s psychological. It’s baffles me that you wouldn’t think treating the underlying causes is better than just taking a jab and covering up the issue. But we clearly have very different mindsets. To me it sounds like you’re saying, that’s too hard just give me the jabs.

It's baffling that you think, with no evidence whatsoever, that it's possible to successfully treat the causes of obesity and that these are mostly psychological. Why is it you think that, have you not researched the matter at all or did you read something and misunderstand it?

RufustheFactuaIReindeer · 28/01/2026 21:25

I dont find these threads triggering

i think people are entitled to their opinions and should be allowed to express them

i did read the article, but i am interested in more of a breakdown depending on the diet, so wli, weightwatchers, Cambridge etc which that article didn’t go into one imagines because the research just isn’t there yet

Bloozie · 28/01/2026 21:25

Whataninterestinglookingpotato · 28/01/2026 21:14

I’ve worked with a fair few people that cooking classes would have been helpful for. But I suppose that is only my anecdotal, lived experience evidence rather than a peer reviewed study.

I've worked with a fair few people who are brilliant cooks and their waistlines are testament to that. Though I suppose the fact that being able to cook makes you fat is only my anecdotal, lived experience rather than a peer reviewed study.

Perimenoanti · 28/01/2026 21:25

Whataninterestinglookingpotato · 28/01/2026 21:16

Look, it’s obviously a very touchy subject for you. I think that the comparison is a bit sick to be honest but obviously you have a different view.

at no point did I say that obese people aren’t trying hard enough. That’s just what you read into it because you’re clearly very sensitive about it. But you do need to address the underlying causes. They’ll be different for everyone but a change of lifestyle is what is needed for most people and some people may do better with support to do that. How ever offended you are by that.

That's you trying very hard to frame me as being triggered and too sensitive. I don't find the comparison sick at all. Obesity kills. The only difference is it does it slowly and often comes as a surprise. But I know you think that unlike cancer you view it as self inflicted and a weakness. Obesity is life limiting and results in premature death. Just like cancer.

I just wondered if I finally get a heart attack or become incapacitated after a stroke and need a carer (provided i didn't die from it) - you would presumably still tell me about willpower and how its my fault? Presumably you think that most people with lung cancer have caused it themselves and you'd be quite happy to lecture about willpower and lifestyle?

Im not reading into it. You said yourself its willpower and yadda yadda. And I say for many it is not and that it is a disease.

SilenceInside · 28/01/2026 21:24

@Whataninterestinglookingpotato WLI enable a lifestyle change for many of the people that use them, that’s one of the many benefits. Because I lost some weight I was able to start exercising regularly and consistently. Both structured exercise and more incidental activity during the course of my normal day. What are the underlying causes that I now need to address? I tend to eat high sugar and high fat foods when I’m a bit stressed or tired, and I live in a society where that kind of food is abundant. That’s my underlying cause.

velvetgeranium · 28/01/2026 21:21

RufustheFactuaIReindeer · 28/01/2026 21:18

I appreciate that it can be difficult to ignore posters for some people

skill worth working on though…

You might work on the skill of ignoring WLI threads outside the WLI board.
They are apparently intensely triggering for some on WLI.

You might also work on the skill of reading the article linked in the OP which the discussion is about. And/or consider a name change, as factual does not seem to be a major attribute given your earlier post:

I would be interested In evidence that shows that people on WLI gain at 4x the rate of slimming world, keto etc…not from you OP, i know you don’t know

Whataninterestinglookingpotato · 28/01/2026 21:21

Perimenoanti · 28/01/2026 21:10

Oh you could absolutely life a lifestyle to significantly reduce the risks of some cancers.

Great that you also just confirmed you don't actually understand obesity 👊

of course you can live a lifestyle that reduces your risk of cancer but many many cancers will strike for no real reason.

very few people are obese because of health conditions. Mostly it’s psychological. It’s baffles me that you wouldn’t think treating the underlying causes is better than just taking a jab and covering up the issue. But we clearly have very different mindsets. To me it sounds like you’re saying, that’s too hard just give me the jabs.

Bloozie · 28/01/2026 21:20

Wegovy's patent expires in 2031. Ozempic's patent expires in 2032. Mounjaro's patent expires in 2036. Competitively priced generic GLP-1s will soon flood the market. I'm on MJ. If I have to pay for a maintenance dose to stay at a healthy weight, I will. Alternatives may present themselves in the meantime.

GLP-1 receptor drugs have been used successfully to support people with diabetes for decades. It's not an experimental drug. Those of you gleefully rubbing your hands together at the possibility of the weak-willed fatties growing a third head as an unintended consequence of using WLIs when they could have simply eaten less and exercised more, like they do, will be disappointed.

Weight regain after rapid weight loss is a risk no matter how the weight is lost.

DarkForces · 28/01/2026 21:20

velvetgeranium · 28/01/2026 21:15

No, they cannot just be ignored. Every thread ends the same way. A swarm and a hammering and finally only the same posters shutting down any conversation about WLI that isn't a MLM-type hype fest are left, congratulating themselves and calling all the other posters wanting a normal discussion "idiots".

Ergo, a simple discussion is not allowed.

Why do you think I should debate a regulated medication that I am validly prescribed? Why do you think I wouldn't be grateful and speak out about a medication that will give me more healthy years with the people I love. Of all the things I've done in my life investing in weight loss injections is probably the best health wise other than actually life saving treatments I've had. I just have no patience with faux concern and scaremongering. If there was a big debate about the risk benefits they wouldn't be authorised for being prescribed by pharmacists. It's based on evidence not assumptions and anecdotes

sprigatito · 28/01/2026 21:20

I don’t understand all the comments about “not being allowed” to discuss WLI or anything else. Absolutely nobody is stopping anybody from posting exactly what they want to, as long as it’s not a personal attack. If you mean that you lack the resilience to cope with comments from people who disagree with you - and are similarly exercising their freedom to post - then own that. Otherwise, stop whining about being persecuted and get on with the discussion.

Binus · 28/01/2026 21:20

Whataninterestinglookingpotato · 28/01/2026 21:14

I’ve worked with a fair few people that cooking classes would have been helpful for. But I suppose that is only my anecdotal, lived experience evidence rather than a peer reviewed study.

It is, but I don't think anyone disputes that there are people for whom cooking lessons would be useful. It's just that's a very different point to whether they do anything to make obese people get and stay a healthy BMI.

But they can still be useful without being something that curbs existing obesity. And it's best those resources are directed at the people who'd most benefit from them- because they're such a good thing when needed!

RufustheFactuaIReindeer · 28/01/2026 21:19

Deffo skill i need to work on…not on this thread 😀

RufustheFactuaIReindeer · 28/01/2026 21:18

I appreciate that it can be difficult to ignore posters for some people

skill worth working on though…

RufustheFactuaIReindeer · 28/01/2026 21:16

Ergo, a simple discussion is not allowed

ergo 😀

MN allow discussion….individual posters may not

Whataninterestinglookingpotato · 28/01/2026 21:16

Perimenoanti · 28/01/2026 21:13

I also think the quite valid comparison shocked you and you probably didn't see another way but to insult obese people for not trying hard enough according to your belief.

Look, it’s obviously a very touchy subject for you. I think that the comparison is a bit sick to be honest but obviously you have a different view.

at no point did I say that obese people aren’t trying hard enough. That’s just what you read into it because you’re clearly very sensitive about it. But you do need to address the underlying causes. They’ll be different for everyone but a change of lifestyle is what is needed for most people and some people may do better with support to do that. How ever offended you are by that.

soupyspoon · 28/01/2026 21:15

We have a food and social/environmental culture in thsi country which encourages over eating

Posters are keen, almost to the point of obsession to repeat the false narrative that obese people need therapy or counseling to fix their 'unhealthy relationship' with food.

Society, supported by government and food industries have promoted an unhealthy relationship with food for all of us.

Boringly I did some calorie calucations on another thread ages ago, you dont need to binge eat or rely on food as some sort of emotional crutch to get obese. It can happen over the course of a year. pound by pound. Eating a few biscuits a day, an extra blob of butter, holidays, christmases, birthdays, celebrations. We dont need therapy for this.

Society, supported by government have promoted a car based system, a system which doesnt even allow kids to have a proper lunchtime at school, a system which means that there isnt time to prepare batch cooking .

We are replicating America and Australia in their food habits and our weight shows this.

We dont need therapy for this either, we need government to support a healthy physical and food environment, just like in other countries.

velvetgeranium · 28/01/2026 21:15

RufustheFactuaIReindeer · 28/01/2026 21:12

People are not allowed to ask questions about or ponder the implications of WLI on MN, that is clear

those posters can be ignored and the phrase used was ‘not allowed…on MN’ when quite obviously MN is allowing these threads

No, they cannot just be ignored. Every thread ends the same way. A swarm and a hammering and finally only the same posters shutting down any conversation about WLI that isn't a MLM-type hype fest are left, congratulating themselves and calling all the other posters wanting a normal discussion "idiots".

Ergo, a simple discussion is not allowed.

Whataninterestinglookingpotato · 28/01/2026 21:14

Binus · 28/01/2026 21:10

There's a lot of 'I'd say' and 'seems' in here, but no actual proof. And there's a reason for that, which is that these are just beliefs you hold. If you try looking for evidence that cookery classes assist obese people in becoming and staying a healthy BMI, none will be forthcoming.

It's one of those things that sounds nice, and certainly it would be a good thing if more people knew how to cook adequately. But the obesity stuff is merely what you wish was true.

I’ve worked with a fair few people that cooking classes would have been helpful for. But I suppose that is only my anecdotal, lived experience evidence rather than a peer reviewed study.

Perimenoanti · 28/01/2026 21:13

Whataninterestinglookingpotato · 28/01/2026 21:08

Wow, I know being obese is a touchy subject for many but I can’t believe you just likened it to cancer patients. That’s a bit much. You can’t cure cancer with diet exercise and will power. While there are some people medical conditions that will make you gain weight through no fault of their own, that’s not the case for most. For most it comes down to their relationship with food.

I also think the quite valid comparison shocked you and you probably didn't see another way but to insult obese people for not trying hard enough according to your belief.

RufustheFactuaIReindeer · 28/01/2026 21:12

velvetgeranium · 28/01/2026 20:43

Having an immediate swarm of the same posters appear on every thread to hammer the OP and anyone else wishing to discuss anything other than how miraculous the injections are is not my idea of a discussion.

People are not allowed to ask questions about or ponder the implications of WLI on MN, that is clear

those posters can be ignored and the phrase used was ‘not allowed…on MN’ when quite obviously MN is allowing these threads

Perimenoanti · 28/01/2026 21:10

Whataninterestinglookingpotato · 28/01/2026 21:08

Wow, I know being obese is a touchy subject for many but I can’t believe you just likened it to cancer patients. That’s a bit much. You can’t cure cancer with diet exercise and will power. While there are some people medical conditions that will make you gain weight through no fault of their own, that’s not the case for most. For most it comes down to their relationship with food.

Oh you could absolutely life a lifestyle to significantly reduce the risks of some cancers.

Great that you also just confirmed you don't actually understand obesity 👊

Binus · 28/01/2026 21:10

Whataninterestinglookingpotato · 28/01/2026 21:02

i would say that the is evidence that gaining a healthier relationship with food, cooking lower fat meals from scratch and exercising correctly and regularly helps to keep weight off.

people struggle with these things for many different reasons but weight loss injections alone just seem like a massive sticking plaster rather than dealing with the underlying reason for obesity. It won’t work for everyone as people have got to be motivated and actually want to engage with it, but it might give some people a fighting chance of coming off the injections and not regaining weight. As someone who has lost weight and keep it off you do need to change your whole life. Society is built to make us over weight, it’s easy to gain and a lot harder not to slip back into old habits once the weight loss “journey” is over.

There's a lot of 'I'd say' and 'seems' in here, but no actual proof. And there's a reason for that, which is that these are just beliefs you hold. If you try looking for evidence that cookery classes assist obese people in becoming and staying a healthy BMI, none will be forthcoming.

It's one of those things that sounds nice, and certainly it would be a good thing if more people knew how to cook adequately. But the obesity stuff is merely what you wish was true.

Whataninterestinglookingpotato · 28/01/2026 21:08

Perimenoanti · 28/01/2026 20:59

Lots of people who receive cancer treatment die anyway. They hope for a cure, or some quality of life for longer. But for fat people that's not acceptable, eh?

Wow, I know being obese is a touchy subject for many but I can’t believe you just likened it to cancer patients. That’s a bit much. You can’t cure cancer with diet exercise and will power. While there are some people medical conditions that will make you gain weight through no fault of their own, that’s not the case for most. For most it comes down to their relationship with food.

Perimenoanti · 28/01/2026 21:05

Whataninterestinglookingpotato · 28/01/2026 21:02

i would say that the is evidence that gaining a healthier relationship with food, cooking lower fat meals from scratch and exercising correctly and regularly helps to keep weight off.

people struggle with these things for many different reasons but weight loss injections alone just seem like a massive sticking plaster rather than dealing with the underlying reason for obesity. It won’t work for everyone as people have got to be motivated and actually want to engage with it, but it might give some people a fighting chance of coming off the injections and not regaining weight. As someone who has lost weight and keep it off you do need to change your whole life. Society is built to make us over weight, it’s easy to gain and a lot harder not to slip back into old habits once the weight loss “journey” is over.

Its great this worked for you, but you are feeding into the willpower narrative. WLI enable people to change their lifestyle. Im starting to gain back more mobility. My aches and pains are gone. They allow me to make changes that go way beyond my diet.

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