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AIBU?

Share your dilemmas and get honest opinions from other Mumsnetters.

to feel uneasy about what this means long term rather than surprised by the weight regain itself?

682 replies

HazelMember · 28/01/2026 18:03

I’ve just read a BBC article about research into weight loss injections like Ozempic and Wegovy showing that people who stop taking them tend to regain weight quite quickly.

I’m not shocked that weight comes back. That happens after most weight loss attempts whether they involve medication or not.

These drugs are increasingly talked about as something people might take for years or even indefinitely. That raises questions for me about what happens when someone cannot afford them anymore, when supply changes, when side effects become an issue or when a person simply does not want to stay on a medication for life.

If stopping leads not just to regain but to a fairly rapid rebound, it feels less like a temporary aid and more like something that is very hard to step away from once started. That sits oddly with how casually they are sometimes discussed.

AIBU to think the real issue here is not that people regain weight after stopping, but whether we are quietly normalising a treatment that may be difficult to discontinue once begun? Or is this simply the reality of managing a chronic condition?

A woman, wearing bright red nail polish and unbuttoned blue jeans, injects herself into the skin and soft tissue of her lower abdomen with an obesity jab pen.

People coming off weight-loss injections risk fast weight gain

Overweight people shed large amounts on jabs but gain 0.8 kg a month on average once off them, study shows.

https://www.bbc.co.uk/news/articles/c050ljnrv2qo

OP posts:
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14
BatchCookBabe · 28/01/2026 21:51

I'm not being funny @HazelMember but I really can't see the point of this thread. Why have you posted it? Just so you can gloat about how people who spends 1000s of pounds on weight loss injections and lose say, 7 stone, will regain it all all as soon as they come off the jabs? Ha ha ha. Hmm

Seriously, what is the object of this thread?

AbbaDabbaDooh · 28/01/2026 21:51

I'm hoping it changes the food available in shops, but also worried that it becomes a lot more expensive because people are eating less.

I'm also concerned about loss of muscle mass from sudden weight loss. It is catastrophic in older age.

I think we conceptualise the problem wrong- we are not obese, we are under muscled. My cholesterol improved a lot when I was lifting weights.

Perimenoanti · 28/01/2026 21:48

soupyspoon · 28/01/2026 21:46

Gaslighting innit

These threads are all the same.

Yes its abusive. Plot twist: i have seen a therapist for 4 years and remained obese 😂

Perimenoanti · 28/01/2026 21:46

DarkForces · 28/01/2026 21:44

I've tried that. I know what to do. The medication enables me to put my knowledge into practice. I can't do this when my body is fighting me constantly as it pretends it's starving and messes with my blood sugar levels and hormones. The medication stabilises this. It's not like normal hunger. I'm fine with that and keep my dose low so I still experience hunger. It's very very different off the injections. I don't need therapy or advice. I need a prescribed medicine to enable me to stay healthy. If you haven't experienced it lucky you, but the idea of being lectured by people who can't understand what it's like is more likely to send me to a pile of cream cakes than actually help.

But WILLPOWER

soupyspoon · 28/01/2026 21:46

Perimenoanti · 28/01/2026 21:45

One last time for you: for some that's not possible. Its better to stay on medication and accept the risks as the risks of obesity are far greater.

The side effects are not uncertain. You must have been reading the daily mail. The medication has been around for 20+ years.

There really isn't much depth to anything you say. Its all quite superficial. As soon someone challenges you you backtrack 'I didn't say this, what i meant is, you read something into it, you get emotional'. I tend to disengage with people showing this pattern and that's what im going to do.

Gaslighting innit

These threads are all the same.

EmeraldShamrock000 · 28/01/2026 21:46

Within the next year there’ll be cheaper maintenance pill brought out. It is a booming business and will eventually be tailored to suit all needs and pockets.

Perimenoanti · 28/01/2026 21:45

Whataninterestinglookingpotato · 28/01/2026 21:37

How did you come to the conclusion that using weight loss injections as a tool to loose weight and start the lifestyle changes was against my narrative? You really are reading too much into things and getting unnecessarily offended.

my point is that people may need support to keep up enough lifestyle changes to maintain weight loss after the jabs. Because surely changing your lifestyle and coming off them is preferable to long term meds with uncertain side affects. But you don’t seem to want that.

One last time for you: for some that's not possible. Its better to stay on medication and accept the risks as the risks of obesity are far greater.

The side effects are not uncertain. You must have been reading the daily mail. The medication has been around for 20+ years.

There really isn't much depth to anything you say. Its all quite superficial. As soon someone challenges you you backtrack 'I didn't say this, what i meant is, you read something into it, you get emotional'. I tend to disengage with people showing this pattern and that's what im going to do.

Summerunlover · 28/01/2026 21:44

I have lost 2 stone on them but couldn’t afford to carry on. But since been off them have carried on losing. I have to calorie count everything, and exercise every day. But the jab gave me the chance to start healthy habits and I am not starting at over weight I am able to comfortably exercise. I find it so odd so many people keep posting this. Especially when they have never taken it themselves. People take drugs every day for mental health no one says a thing. But people are obsessed with the use of the jabs. I soon as I can afford it again I am back on it. It changed my whole life it solved a lot of my other issues with my disability. And my stomach issues, I also stopped being g anxious. Best drug I have Ever taken.

Binus · 28/01/2026 21:44

RufustheFactuaIReindeer · 28/01/2026 21:25

I dont find these threads triggering

i think people are entitled to their opinions and should be allowed to express them

i did read the article, but i am interested in more of a breakdown depending on the diet, so wli, weightwatchers, Cambridge etc which that article didn’t go into one imagines because the research just isn’t there yet

I quite like them! It really interests me the way people get so attached to theories about obesity and weight loss.

It's fascinating because it's obvious where the idea that there must be non drug cures for obesity comes from. It's what we were told for a long time, since it was either that or we were completely screwed. So I get that. When provided with a narrative, people invented the rest themselves, and some of them don't do well with the priors changing.

DarkForces · 28/01/2026 21:44

Whataninterestinglookingpotato · 28/01/2026 21:37

How did you come to the conclusion that using weight loss injections as a tool to loose weight and start the lifestyle changes was against my narrative? You really are reading too much into things and getting unnecessarily offended.

my point is that people may need support to keep up enough lifestyle changes to maintain weight loss after the jabs. Because surely changing your lifestyle and coming off them is preferable to long term meds with uncertain side affects. But you don’t seem to want that.

I've tried that. I know what to do. The medication enables me to put my knowledge into practice. I can't do this when my body is fighting me constantly as it pretends it's starving and messes with my blood sugar levels and hormones. The medication stabilises this. It's not like normal hunger. I'm fine with that and keep my dose low so I still experience hunger. It's very very different off the injections. I don't need therapy or advice. I need a prescribed medicine to enable me to stay healthy. If you haven't experienced it lucky you, but the idea of being lectured by people who can't understand what it's like is more likely to send me to a pile of cream cakes than actually help.

Binus · 28/01/2026 21:40

Whataninterestinglookingpotato · 28/01/2026 21:33

A quick Google search will tell you that less than 5% of all obese people are obese primarily because of medical conditions.

Yes, that's why I specifically highlighted your claims about psychological causes and addressing the root as the problems. Both entirely invented.

DarkForces · 28/01/2026 21:38

velvetgeranium · 28/01/2026 21:31

It is indeed. But on these thread we are not talking about just breezing over one individual annoying poster. It is a posse, and I recognise most of the names, that comes in as if a bat signal has gone off, and shuts down all conversation.

You seem like a nice reindeer. Go back and look at some of the threads, same names over and over, same progression - or lack of progression, as any discussion that is not utterly positive about WLI is apparently upsetting, and accusations must be hurled at anyone daring to try to discuss any downside - and same end: the same names congratulating themselves.

Why shouldn't I defend a medicine that's reduced my risk of a whole raft of life limiting conditions? Why shouldn't I point out that the evidence supports their use for people who use them correctly? I'm not going to shut up or apologise for speaking up for something that has transformed my life.

Whataninterestinglookingpotato · 28/01/2026 21:37

Perimenoanti · 28/01/2026 21:29

No, there is a reason for all cancers. The scientists just haven't found it all. Likely the factors are complex, just as they are with obesity. Research is being done on both. HTH.

I didn't say obesity is caused by health conditions. I say obesity has devastating effects on health and often kills. I also said WLI enabled me to make lifestyle changes beyond my diet, but that goes against your narrative so you couldn't pick up on it.

How did you come to the conclusion that using weight loss injections as a tool to loose weight and start the lifestyle changes was against my narrative? You really are reading too much into things and getting unnecessarily offended.

my point is that people may need support to keep up enough lifestyle changes to maintain weight loss after the jabs. Because surely changing your lifestyle and coming off them is preferable to long term meds with uncertain side affects. But you don’t seem to want that.

velvetgeranium · 28/01/2026 21:36

Perimenoanti · 28/01/2026 21:34

But you are here too!?

  1. not in a posse
  2. interested in discussing such things
soupyspoon · 28/01/2026 21:35

Whataninterestinglookingpotato · 28/01/2026 21:21

of course you can live a lifestyle that reduces your risk of cancer but many many cancers will strike for no real reason.

very few people are obese because of health conditions. Mostly it’s psychological. It’s baffles me that you wouldn’t think treating the underlying causes is better than just taking a jab and covering up the issue. But we clearly have very different mindsets. To me it sounds like you’re saying, that’s too hard just give me the jabs.

The basic underlying reason is we eat too much as a society

We are animals, we are flooded with food opportunities, cheap, socially acceptable, convenient.

So we need help to reduce our wants to eat less. We are hard wired to eat when available. Its how we now exist as a species.

Animals will eat when they can, its how they survive.

We do not have more or less 'psychological underlying reasons' than any other countries around the world.

We have a vastly different cultural attitude to overeating than countries which have less of a problem with obesity, although they too are catching up as they adopt American/UK style food cultures. UPFs encourage the body to literally change how it responds perpetuating a cycle.

Perimenoanti · 28/01/2026 21:34

velvetgeranium · 28/01/2026 21:31

It is indeed. But on these thread we are not talking about just breezing over one individual annoying poster. It is a posse, and I recognise most of the names, that comes in as if a bat signal has gone off, and shuts down all conversation.

You seem like a nice reindeer. Go back and look at some of the threads, same names over and over, same progression - or lack of progression, as any discussion that is not utterly positive about WLI is apparently upsetting, and accusations must be hurled at anyone daring to try to discuss any downside - and same end: the same names congratulating themselves.

But you are here too!?

RufustheFactuaIReindeer · 28/01/2026 21:33

Will do velvet

Whataninterestinglookingpotato · 28/01/2026 21:33

Binus · 28/01/2026 21:26

It's baffling that you think, with no evidence whatsoever, that it's possible to successfully treat the causes of obesity and that these are mostly psychological. Why is it you think that, have you not researched the matter at all or did you read something and misunderstand it?

A quick Google search will tell you that less than 5% of all obese people are obese primarily because of medical conditions.

velvetgeranium · 28/01/2026 21:31

RufustheFactuaIReindeer · 28/01/2026 21:26

And i even said that the skill of ignoring posters is a skill i need to work on 🤷🏻

its very difficult to do

It is indeed. But on these thread we are not talking about just breezing over one individual annoying poster. It is a posse, and I recognise most of the names, that comes in as if a bat signal has gone off, and shuts down all conversation.

You seem like a nice reindeer. Go back and look at some of the threads, same names over and over, same progression - or lack of progression, as any discussion that is not utterly positive about WLI is apparently upsetting, and accusations must be hurled at anyone daring to try to discuss any downside - and same end: the same names congratulating themselves.

DarkForces · 28/01/2026 21:31

Whataninterestinglookingpotato · 28/01/2026 21:28

Not everyone who is obese needs cooking lessons 😂. I find it amusing that everyone is so offended by this. All I meant by it is that practical support for lifestyle changes should be available along side. That will be different for everyone depending on need.

No ta. I'm quite capable of losing weight in a healthy way. The weight loss injections enable me to put my knowledge into action without my body screaming at me constantly that I need more food. I'm perfectly healthy and on a long term maintenance dose. No more interventions needed.

Perimenoanti · 28/01/2026 21:29

Whataninterestinglookingpotato · 28/01/2026 21:21

of course you can live a lifestyle that reduces your risk of cancer but many many cancers will strike for no real reason.

very few people are obese because of health conditions. Mostly it’s psychological. It’s baffles me that you wouldn’t think treating the underlying causes is better than just taking a jab and covering up the issue. But we clearly have very different mindsets. To me it sounds like you’re saying, that’s too hard just give me the jabs.

No, there is a reason for all cancers. The scientists just haven't found it all. Likely the factors are complex, just as they are with obesity. Research is being done on both. HTH.

I didn't say obesity is caused by health conditions. I say obesity has devastating effects on health and often kills. I also said WLI enabled me to make lifestyle changes beyond my diet, but that goes against your narrative so you couldn't pick up on it.

EmeraldShamrock000 · 28/01/2026 21:29

I have no doubt that the jab will help people change their mindset around food and their stomach will change size, they’ll be in a routine of moving more, probably part of a local exercise class.

sprigatito · 28/01/2026 21:28

Bloozie · 28/01/2026 21:25

I've worked with a fair few people who are brilliant cooks and their waistlines are testament to that. Though I suppose the fact that being able to cook makes you fat is only my anecdotal, lived experience rather than a peer reviewed study.

That’s me unfortunately, I am a passionate and competent cook and I love food. Coupled with emotional eating issues, AuDHD sensory seeking and poor impulse control, I’ve struggled with my weight all my adult life. Obesity is miserable and humiliating and painful and I hate it. I don’t really understand slimmer people who make it their life’s work to make people like me feel even worse than we already do. I think being that cruel and twisted is far worse than being fat.

Whataninterestinglookingpotato · 28/01/2026 21:28

Bloozie · 28/01/2026 21:25

I've worked with a fair few people who are brilliant cooks and their waistlines are testament to that. Though I suppose the fact that being able to cook makes you fat is only my anecdotal, lived experience rather than a peer reviewed study.

Not everyone who is obese needs cooking lessons 😂. I find it amusing that everyone is so offended by this. All I meant by it is that practical support for lifestyle changes should be available along side. That will be different for everyone depending on need.

RufustheFactuaIReindeer · 28/01/2026 21:26

And i even said that the skill of ignoring posters is a skill i need to work on 🤷🏻

its very difficult to do

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