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Is it the begining of the end for Weight loss injections?

489 replies

BeginingoftheendforWLI · 02/01/2026 18:54

Just watched a report on BBC news, they did an item on a woman who had type 2 diabetes and was prescribed Mounjaro, doctors were impressed she managed to come off insulin within a month. She had some weightloss and now goes to the gym regularly.

Her doctor admitted that there was widespread concern in the medical field that people who were buying it privately for cosmetic reasons not for medical reasons could face some consequences in the future such as muscle growth and bone degeneration and lack of nutrition - they simply don't have this data at present.

Feel like this is going to be big news in the foreseeable future.

OP posts:
Boohoo76 · 02/01/2026 19:47

MigGirl · 02/01/2026 19:40

I'm not talking about people who are prescribed them by a medical doctor, I'm referring to those buying them over the Internet.

Being prescribe a drug by a doctor is totally different as they will have weighed up the befits vs the risks for that individual first.

They are prescribed by a doctor when they are purchased online (unless someone is selling them illegally).

DarkForces · 02/01/2026 19:46

It's so lovely how many people 'care' about my health now I'm on wlis but didn't when I was obese and at far more risk. Makes me feel all warm inside.

SeekOIt · 02/01/2026 19:46

ColdAsAWitches · 02/01/2026 19:03

It's the beginning of the end, but only in the sense that the injections will be replaced by pills this year. One brand has already been approved by the FDA, and another is expected to be within 6 months.

Do you know what the main difference is between the pills and the injection? The price point? MJ is proving very expensive these days, I'd be very interested in a cheaper option.

PolyVagalNerve · 02/01/2026 19:44

MigGirl · 02/01/2026 19:06

I am concerned about the long term implications of these drugs. I agree they are a great tool and work really well for a lot of people, but I don't agree thay they should be available over the Internet and from online pharmacies. They are a medical drug and they should be monitored by a doctor, weather that be the NHS or private.

And yes I'm aware that would make them more expensive then they are now.

They are prescribed and monitored by a medical team -
yes, even when obtained through private prescription
only qualified doctors can prescribe these medications

Northerngirl821 · 02/01/2026 19:44

WLIs are revolutionising the treatment of obesity and obesity-related conditions such as diabetes. The only issue is around unregulated use which is the same as any other medication.

I suspect as they become more widely available on the NHS, the market for private treatment will shrink rapidly and the companies currently pushing them hard will lose interest as there won’t be enough profit to make it worthwhile. Once they are not being aggressively marketed, inappropriate use is likely to be less of an issue.

This class of drugs has been around for years so it’s highly unlikely that there is going to be any thalidomide-style side effect disaster waiting around the corner. Sorry to disappoint you, OP, but maybe you should instead focus your thoughts on why you REALLY feel this way about WLIs and what that says about you as a person.

Jackiepumpkinhead · 02/01/2026 19:44

Squirrelchops1 · 02/01/2026 19:33

My muscles have never been so strong! Easy 60kg RDL this am, farmers carries with 50kg total etc
..

That’s excellent, you should be really proud! Hoping to be where you are this year.

Tulcan · 02/01/2026 19:42

MigGirl · 02/01/2026 19:40

I'm not talking about people who are prescribed them by a medical doctor, I'm referring to those buying them over the Internet.

Being prescribe a drug by a doctor is totally different as they will have weighed up the befits vs the risks for that individual first.

All weight loss injections are prescribed though. Unless you are buying them illegally.

Jackiepumpkinhead · 02/01/2026 19:42

Youdontseehow · 02/01/2026 19:31

lol as if you work in health care coming away with 💩 like this.

if you do indeed work in health care, I assume you patrol the car parking or take the bins out?

Your comment is why we need the laughing emoji back 😂

DarkForces · 02/01/2026 19:42

devildeepbluesea · 02/01/2026 19:32

You assume correct.

Well he has the power to restrict them then and chose the rules that people are allowed to purchase them so not sure how he let them slip through?

millymollyminging · 02/01/2026 19:42

I think what the OP was saying was that they haven’t been around long enough to know the long term effects. And I agree. There are millions of people taking them now (and, yes I was one) but what will come out year down the line? Who knows?

kiwiane · 02/01/2026 19:41

If I had to wait for my GP’s support I’d be 4 stones heavier with high BP and near-diabetes. Thank goodness those of us that can afford it don’t have to wait for the NHS. I’ve improved my health and it would be good to have support and appreciation for taking this step.

Ukefluke · 02/01/2026 19:41

MigGirl · 02/01/2026 19:35

I'm always wary of any drug I need to take, I have had to take a lot of medication over the years for health problems and I would never take anything I don't absolutely feel I need to. I'm currently on a much newer drug then WLI and the long term side effects are as yet unknown. I really wish I didn't need to take anything. But I can't function without it so have no choice.

Yes I'm concerned about paracetamol overdose as well especially when there is a very simple way to stop this by adding in the correct amount of antidote into each tablet like they do in some countries.

You can never take anything without there being a side effect or risk and its weather the benefits outway the risk. But still there isn't enough regulation around these drugs, as I do know people who are taking then but don't seem to understand that there could be side effects from them. That's where more oversight by a medical professional comes in to make sure people know what they are taking first and how to use them properly.

The side effect I have had ( aside from halving my body weight) is the lowering of high blood pressure to healthy rabge within 2 weeks of starting and the complete disappearance of an auto immune condition I controlled with VERY nasty drugs. I am now off everything and pain free for the first time in decades.
I'll risk it

FindingMeno · 02/01/2026 19:40

I have been very tempted by them.
I think I'm watching and waiting though to see what % of people maintain the weight loss once they've stopped, since I certainly wouldn't want to be on them indefinitely.
I'm not knocking anyone taking them as we all make our own choices. For me, though, I want to see more data over time before I part with hard earned cash.

Jackiepumpkinhead · 02/01/2026 19:40

devildeepbluesea · 02/01/2026 19:31

It’s a well known side effect that they cause tiredness, FFS. We’re not talking in absolutes here. These are new drugs.

I’m sure some people may feel tired (all medication has potential side effects) but I feel great. I have lost 3st, I now work out (strength training) 3 times a week and eat a healthy high protein and high fibre diet. As another PP said, I now feel confident to go to the gym and I can see my body changing. I also have a mild condition which can cause insulin resistance and inflammation, and I feel that’s under control now. It’s right to be cautious but these drugs can be life changing.

MigGirl · 02/01/2026 19:40

Tulcan · 02/01/2026 19:35

Are you? That’s nice of you.

What about the fact that the people who are prescribed them are not in tip top health in the first place? Just like all the other folks who are prescribed medication.

I'm not talking about people who are prescribed them by a medical doctor, I'm referring to those buying them over the Internet.

Being prescribe a drug by a doctor is totally different as they will have weighed up the befits vs the risks for that individual first.

Funnywonder · 02/01/2026 19:39

Her doctor admitted that there was widespread concern in the medical field that people who were buying it privately for cosmetic reasons not for medical reasons could face some consequences in the future such as muscle growth and bone degeneration and lack of nutrition - they simply don't have this data at present.

This is what stands out for me in the OP. People using the injections privately ARE doing it for medical reasons. Or health reasons if you will. It’s not all about fitting into a size 8 dress FFS.

HRTQueen · 02/01/2026 19:39

I’m so touched that so many are so concerned about all the previous obese people and the medication we are taking

I was never aware of how concerned people were before about fat people and I mistakenly took it as judgement

it’s really heart warming 😊

vodkaredbullgirl · 02/01/2026 19:36

tobee · 02/01/2026 19:35

Op has not returned yet I see.

Another dump and run

MigGirl · 02/01/2026 19:35

Ukefluke · 02/01/2026 19:12

If you are "concerned" dont take them. Simple.
Are you cobcerned about paracetamol use as well? Because there are more hospital admissions for that than for GLPs

I'm always wary of any drug I need to take, I have had to take a lot of medication over the years for health problems and I would never take anything I don't absolutely feel I need to. I'm currently on a much newer drug then WLI and the long term side effects are as yet unknown. I really wish I didn't need to take anything. But I can't function without it so have no choice.

Yes I'm concerned about paracetamol overdose as well especially when there is a very simple way to stop this by adding in the correct amount of antidote into each tablet like they do in some countries.

You can never take anything without there being a side effect or risk and its weather the benefits outway the risk. But still there isn't enough regulation around these drugs, as I do know people who are taking then but don't seem to understand that there could be side effects from them. That's where more oversight by a medical professional comes in to make sure people know what they are taking first and how to use them properly.

EdgeOfThirtySeven · 02/01/2026 19:35

CharlotteStreetW1 · 02/01/2026 19:22

Already here. I've just been prescribed with the tablets for Type II Diabetes.

(Feeling very ambivalent about it.)

(Feeling very ambivalent about it.)

Why?

Whoneedsanamesuggestion · 02/01/2026 19:35

I don't even use WLIs and hate seeing these fecking threads! Couldn't you at least keep it to the right board or just not? Lots of people seem to be losing weight using them and they all seem delighted. I am sure they are aware of the horror stories and have made the decision as grown ups to go ahead anyway. Leave them alone fgs! Nobody is forcing them into you

tobee · 02/01/2026 19:35

Op has not returned yet I see.

Tulcan · 02/01/2026 19:35

MigGirl · 02/01/2026 19:06

I am concerned about the long term implications of these drugs. I agree they are a great tool and work really well for a lot of people, but I don't agree thay they should be available over the Internet and from online pharmacies. They are a medical drug and they should be monitored by a doctor, weather that be the NHS or private.

And yes I'm aware that would make them more expensive then they are now.

Are you? That’s nice of you.

What about the fact that the people who are prescribed them are not in tip top health in the first place? Just like all the other folks who are prescribed medication.

tobee · 02/01/2026 19:34

Personally I’d love to be 3 stone lighter but I’m aware that WLIs are likely to take away my appetite and consequently my ability to exercise regularly oreffectively. And that’s the reason I won’t bother. At 52 health is more important than appearance to me.

What? Losing your appetite affects your ability to exercise? You don't lose your appetite for a kick off.

I need to lose about three stone and that will help me to avoid weight related diabetes type 2, help with avoiding the joint problems that run in my family, and help lower my blood pressure that I already have.

Squirrelchops1 · 02/01/2026 19:33

My muscles have never been so strong! Easy 60kg RDL this am, farmers carries with 50kg total etc
..

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