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Is it the begining of the end for Weight loss injections?

489 replies

BeginingoftheendforWLI · 02/01/2026 18:54

Just watched a report on BBC news, they did an item on a woman who had type 2 diabetes and was prescribed Mounjaro, doctors were impressed she managed to come off insulin within a month. She had some weightloss and now goes to the gym regularly.

Her doctor admitted that there was widespread concern in the medical field that people who were buying it privately for cosmetic reasons not for medical reasons could face some consequences in the future such as muscle growth and bone degeneration and lack of nutrition - they simply don't have this data at present.

Feel like this is going to be big news in the foreseeable future.

OP posts:
SilenceInside · 02/01/2026 20:01

@BeginingoftheendforWLI anyone getting a legitimate private prescription from an online prescriber meets the clinical criteria for the medication. It is not for cosmetic reasons, it’s for health reasons. It’s odd that the doctor in this story apparently raised a concern about something that is nothing to do with peiple being legitimately prescribed WLI. There may be an issue with people acquiring POM illegally for conditions that they don’t have, but that’s not going to affect the legitimate uptake of WLI for those who meet the prescribing criteria.

Lolare · 02/01/2026 20:01

Ukefluke · 02/01/2026 19:59

Get back to us when you have maintained your excellent habits for a year.

I have. 5 years of maintenance. No kore kids so no more baby weight. I have an eggs and veg for breakfast. And a salad for lunch. And whatever I want for dinner. That is the only regime I now follow. I make sure to walk as much as possible and rarely use my car. Even with three kids

BeginingoftheendforWLI · 02/01/2026 20:00

MigGirl · 02/01/2026 19:06

I am concerned about the long term implications of these drugs. I agree they are a great tool and work really well for a lot of people, but I don't agree thay they should be available over the Internet and from online pharmacies. They are a medical drug and they should be monitored by a doctor, weather that be the NHS or private.

And yes I'm aware that would make them more expensive then they are now.

Agree with you, someone talking sense. Its well known people are wearing numerous clothes and putting weights in their pockets. The medical companies don't care as they are making billions.

OP posts:
Ukefluke · 02/01/2026 19:59

Lolare · 02/01/2026 19:57

I say this as someone whose lost 50 pounds slowly over the course of 12 months naturally

So many of the people who I’ve seen that have lost weight using jabs look awful. Honestly like they have deflated or were stuck on a deserted island. I, in contrast, have not sagged at all (only 39 and had baby weight to lose).

Being on the jabs for life is really the only option for most. As they haven’t made the changes necessary to maintain such a loss. Who wants to be on medication for life? It will all come back. Magically switching off your appetite is not really a solution. You need to commit to genuine lifestyle changes for a healthy outcome.

Get back to us when you have maintained your excellent habits for a year.

KimuraTan · 02/01/2026 19:59

I think the OP @BeginingoftheendforWLI is referring to the WLIs used without prescription to lose weight but these users not attending the gym to maintain muscle hence losing lean muscle as well as fat and thus losing strength. I completely agree - this will have huge ramifications in the future. It’s such a short sighted move to go on WLI but not build muscle and maintain strength. Natural selection 🙄

MyCatStoleSausages · 02/01/2026 19:59

Her doctor admitted that there was widespread concern in the medical field that people who were buying it privately for cosmetic reasons not for medical reasons could face some consequences in the future such as muscle growth and bone degeneration and lack of nutrition.

I think that this is due to people using these WLI to enable an eating disorder. I've seen it on threads here women on WLI egging each other on with I've eaten 2 peas today and couldn't possibly eat another bite. Losing weight can be addictive, I'd imagine if you are quite large then losing weight fast must feel awesome,discovering that you can eat fuck all in a day and have no hunger signals is like a cheat code to getting skinny fast.

Like anything these injections need to be used responsibly, people need to understand that food doesn't just make you fat or skinny it fuels your body and you need a certain amount of the right foods or your health will suffer. Even with that understanding though there are still people who will get sucked into thinking that it won't happen to them, they'll be fine etc. Skinny has always been desirable and some people have always been willing to risk their health to get there.

Tattiana · 02/01/2026 19:58

Funnywonder · 02/01/2026 19:39

Her doctor admitted that there was widespread concern in the medical field that people who were buying it privately for cosmetic reasons not for medical reasons could face some consequences in the future such as muscle growth and bone degeneration and lack of nutrition - they simply don't have this data at present.

This is what stands out for me in the OP. People using the injections privately ARE doing it for medical reasons. Or health reasons if you will. It’s not all about fitting into a size 8 dress FFS.

I mean I’m sure there are many people doing it for health reasons but I think in the main it is absolutely about being thin/cosmetic. I know LOADS of people on WLIs who perhaps needed to lost a stone or two, but they certainly weren’t life-threateningly obese.

Lolare · 02/01/2026 19:57

I say this as someone whose lost 50 pounds slowly over the course of 12 months naturally

So many of the people who I’ve seen that have lost weight using jabs look awful. Honestly like they have deflated or were stuck on a deserted island. I, in contrast, have not sagged at all (only 39 and had baby weight to lose).

Being on the jabs for life is really the only option for most. As they haven’t made the changes necessary to maintain such a loss. Who wants to be on medication for life? It will all come back. Magically switching off your appetite is not really a solution. You need to commit to genuine lifestyle changes for a healthy outcome.

Nannyogganny · 02/01/2026 19:56

Garroty · 02/01/2026 19:55

It's not exactly easy to get WLI for 'cosmetic' reasons. Even if someone's primary motivation for taking them is to improve the way they look, you can still only get them (safely at least) if you're obese. If you're obese you're at risk of a wide range of health concerns which weight loss can assist with. It's not like you don't get the medical benefit of weight loss just because your primary purpose is to look better.

All medication has side effects. When it comes to WLI the side effects are generally less concerning than the risks of being obese.

'Obese' is not that big for some people.

Im a size 14 - 16. Im short 5 foot 3.

If I use a BMI calculator, It calculates me as obese. Therefore, I was able to get Mounjaro

Arraminta · 02/01/2026 19:56

DarkForces · 02/01/2026 19:46

It's so lovely how many people 'care' about my health now I'm on wlis but didn't when I was obese and at far more risk. Makes me feel all warm inside.

Yes me too. I have 2 acquaintances who regularly express faux concern about my 'worrying thinness' (I'm 5ft 6 and 9st 8lbs, so hardly skin and bone).

I wonder why they never expressed any concerns when I was 3 stones heavier and mentioned my cholesterol was creeping up and up?

usedtobeaylis · 02/01/2026 19:55

BeginingoftheendforWLI · 02/01/2026 19:51

I'm just saying what the news report said - they are great for people that need it for medical reasons, cosmetic reason not so much. Do you normally struggle with understanding basic stuff?

So why is it the beginning of the end for WLIs?

BeginingoftheendforWLI · 02/01/2026 19:55

TheRealMagic · 02/01/2026 18:56

What are you on about? You watched a report about a WLI success story and from that concluded that they are actually a terrible thing that will soon be stopped? Do you normally struggle with comprehension?

The report was about a success story was for the woman who had diabetes and had managed to come off insulin. People taking it for cosmetic reasons not so much.

OP posts:
Garroty · 02/01/2026 19:55

It's not exactly easy to get WLI for 'cosmetic' reasons. Even if someone's primary motivation for taking them is to improve the way they look, you can still only get them (safely at least) if you're obese. If you're obese you're at risk of a wide range of health concerns which weight loss can assist with. It's not like you don't get the medical benefit of weight loss just because your primary purpose is to look better.

All medication has side effects. When it comes to WLI the side effects are generally less concerning than the risks of being obese.

Alpacajigsaw · 02/01/2026 19:54

chellewillnotbebeaten · 02/01/2026 19:04

I agree - admittedly I don’t need wli but I have been very overweight in the past and would have probably snapped them up at the time - early to mid twenties I fried every fad diet, pharmacy only shakes, everything (heartbreak diet solved the issue in the end haha) BUT I do think they are poorly regulated/controlled…… people are injecting insulin when they are not diabetic! That’s so dangerous! (I work in healthcare and have seen devastating effects and death from incorrect insulin management for people that actually are diabetic). Then again, I smoke and ecig and I’m sure in years to come there will be consequences with that.

What’s people injecting insulin got to do with WLI?

OP. Those of us taking them responsibly know they are serious meds but - the potential risks are less of a concern than the known risks of obesity. These kind of drugs are here to stay in how we manage and treat obesity and will improve people’s lives in a number of ways in years to come.

they are not for cosmetic weight loss they are for the serious health condition of obesity

BillieWiper · 02/01/2026 19:54

I don't think so. They are getting cheaper more popular and more effective. So maybe jabs will be replaced with tablets. That's already starting to come in.

Of course there are side effects and obviously the long term are unknown. But the health outcomes of morbidly obese people are usually markedly worse than anyone using GLP1 and/or of a healthy weight.

BeginingoftheendforWLI · 02/01/2026 19:53

miamo12 · 02/01/2026 18:58

You obviously didn’t see the story. The doctor said that it worked for short periods to reverse medical conditions when the person was significantly overweight, worries were for those not significantly overweight and not eating enough.

Pretty sure I watched it, then came here to post about it.

OP posts:
usedtobeaylis · 02/01/2026 19:53

devildeepbluesea · 02/01/2026 19:24

I have a good friend who is a senior medic, working in endocrinology- no idea how related this field is but I’m guessing at least a bit.

He maintains that WLIs are great for those who are morbidly obese and the danger of whose co-morbidities outweigh the unknown of WLIs.

However for people who only have a couple of stone to lose it could be cumulatively detrimental. The loss of muscle tone, bone density and who knows what else because we just don’t know yet, outweigh the health benefits of weighing less.

Personally I’d love to be 3 stone lighter but I’m aware that WLIs are likely to take away my appetite and consequently my ability to exercise regularly oreffectively. And that’s the reason I won’t bother. At 52 health is more important than appearance to me.

They don't have to take away your appetite. You don't have to take the maximum dose. I have stayed on lower doses and it hasn't affected my ability to exercise or made me unable to eat. Some people probably prefer having their appetite suppressed, people used to smoke for that reason, but many people taking Mounjaro eat what they're finding is normally.

Nannyogganny · 02/01/2026 19:51

I agree. Also, I feel it is not researched enough at all.

They currently sell WLI over the counter to nearly everyone over a certain weight

I took Mounjaro for six months. It made me so severely sick. I had to stop.

I'm not saying that there is something inherently wrong with mounjaro, just that it didnt work with my body.

They should research it more, and not just sell a strong drug to absolutely everyone over a certain weight

BeginingoftheendforWLI · 02/01/2026 19:51

TheRealMagic · 02/01/2026 18:56

What are you on about? You watched a report about a WLI success story and from that concluded that they are actually a terrible thing that will soon be stopped? Do you normally struggle with comprehension?

I'm just saying what the news report said - they are great for people that need it for medical reasons, cosmetic reason not so much. Do you normally struggle with understanding basic stuff?

OP posts:
PolyVagalNerve · 02/01/2026 19:50

devildeepbluesea · 02/01/2026 19:24

I have a good friend who is a senior medic, working in endocrinology- no idea how related this field is but I’m guessing at least a bit.

He maintains that WLIs are great for those who are morbidly obese and the danger of whose co-morbidities outweigh the unknown of WLIs.

However for people who only have a couple of stone to lose it could be cumulatively detrimental. The loss of muscle tone, bone density and who knows what else because we just don’t know yet, outweigh the health benefits of weighing less.

Personally I’d love to be 3 stone lighter but I’m aware that WLIs are likely to take away my appetite and consequently my ability to exercise regularly oreffectively. And that’s the reason I won’t bother. At 52 health is more important than appearance to me.

The weight someone is to receive a prescription is in the category of health risks due to obesity
even a couple of stones overweigjt increases significant health risks
obesity is the biggest health crisis humans have faced
it’s not just about appearance -
if someone is a healthy weight they aren’t prescribed weight loss medication

Arraminta · 02/01/2026 19:49

MigGirl · 02/01/2026 19:40

I'm not talking about people who are prescribed them by a medical doctor, I'm referring to those buying them over the Internet.

Being prescribe a drug by a doctor is totally different as they will have weighed up the befits vs the risks for that individual first.

You do know that WLI are prescribed by pharmacists? And that they're far more knowledgeable about drugs than doctors are?

usedtobeaylis · 02/01/2026 19:49

It looks like yet again people are confusing Ozempic and Mounjaro.

Mounjaro is licenced for obesity. You can only get it on prescription. If anyone is telling lies to obtain it, that is not on the people taking it legitimately. In that sense it is no different from getting your pill from an online pharmacy.

Additionally, almost every side effect people are 'concerned about' is a side effect of general rapid weight loss or of obesity, not of Mounjaro specifically.

OtherS · 02/01/2026 19:48

They don't cause any more bone or muscle loss than if you lost the weight as fast naturally, do they? I thought the loss was purely down to the actual weight loss rather than anything the pill was doing.

ChazsBrilliantAttitude · 02/01/2026 19:48

Any form of rapid weight loss can lead to loss of lean muscle mass and impacts on bone density. People who have bariatric surgery are also at risk of nutrient deficiencies due to absorption issues.

That is why people taking WLI (or who have had weight loss surgery) are advised to eat extra protein, lift heavy weights and consider multivitamins etc if their diet is limited.

These medications are not a quick fix but a tool to help with lifestyle changes. As with any diet, if you make rubbish choices your health will suffer. You can lose weight eating only 3 Mars bars a day but it’s not a healthy thing to do.

maddiemookins16mum · 02/01/2026 19:47

People buying it privately (like me) are potentially saving the NHS money. I’ve reduced my blood pressure big time in the 6 months I’ve been on MJ (down from 13 stone 12 to 10 stone 8). This time last year I struggled to walk any huge distance, yesterday I swam 20 lengths after using the treadmill for 30 mins on a 10 incline.

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