Is it the begining of the end for Weight loss injections?

@Catpuss66 Psoriasis and Psoriatic arthritis. Have read of positive effects on other autoimmune conditions as well on various forums.

Can I ask which autoimmune disease?

People seem to forget that. To be obese at my height (5ft 4) I have to be 2 stone over a healthy weight, that would be a 14-16 also. Just because I'm short doesnt mean it's not unhealthy to be over 30 BMI just because its not 5 or 6 stone to lose.

I am now BMI 25 but my waist measurement is still more 3 inches over a healthy size for my height, something the medical profession is taking as seriously as BMI now. People have lost sight of a healthy looking weight now for sure.

And didn't explain why the article has made her think this.

Insulin has been sold online to people AS WLI's there is no mistake. That has and probably is still happening and is extremely dangerous....

She said the beginning of the end - there’s a difference.

I'm 50 and have lost 30 pounds. BMI now 24 instead of 29.

I've always exercised but my joints were starting to ache from the additional weight. My HR is in the 120s when I run now instead of 140s, so I can do a lot more with less strain on my heart. I've started open water swimming which I'd never had done 30lbs heavier. I've had lessons and learned front crawl. I've started circuit training and keep up with people half my age. Everything I do from getting out of bed to weights and yoga is easier. Looking better is a mere side effect. I'm much fitter and have zero menopause symptoms in spite of my periods stopping 12 months ago, and having endometriosis and PCOS. There is certainly no inability to exercise, quite the reverse.

It's interesting that you got this from what OP wrote. Because actually what you've written here is better than what she did. Why haven't you mentioned that the whole premise of her thread is speculation about 'the end' of WLIs, based on absolutely bugger all?

And once again, nobody is telling you that you're not allowed to debate the issue. You are literally squashing debate yourself by pretending that detailed criticism of arguments is the same thing as trying to stop them from being made. I've engaged more with what OP wrote than you have!

Edit- sorry that was meant to quote, dunno where it went

Why would there be data on people who aren’t obese or significantly overweight with weight related health conditions taking a prescription medication for obesity? Medical studies don’t usually focus on the outcomes for people who illegally misuse medication.

The clinical trials looked at the outcomes for obese people taking these medications. There are known side effects as a result of those trials. We also already know about the issues around any kind of rapid weight loss, like muscle loss, bone density and nutrition. That’s why anyone prescribed WLI is advised to eat nutritious food and exercise.

So what exactly are the new revelations in this BBC story that are important to discuss?

Nice swerve, but let’s not pretend you weren’t using it as an insult.

Ignoramus is Latin for “we do not know”, so very apt I think - we are simply informing you of the facts so you need not be ignorant of them.

It’s a pretty tame word to use (and not the one I would like to use).

God this is frustrating.

You say OP’s opinion is ill informed but her entire point is that issues are starting to come to the fore that could potentially create long term health concerns for users and this should be discussed. How is that ill informed? Why are users so blind to the idea that 10, 20 years down the line people might wish they’d never taken WLI because the loss of muscle mass means they’re now wizened 60somethings? And no, I am not saying for a second that will happen, but why aren’t we allowed to debate the possibility?

Thank you for proving my point.

I didn't say OP wasn't entitled to post, and you couldn't possibly have got that from my post. Having the right to an opinion doesn't mean the opinion is remotely well informed. And OPs isn't.

Which goes to my point. If you want to argue about cult like mentalities and not being allowed to make valid criticism, you need to pick someone who had something sensible to say. You weren't discerning enough. If more of you were capable of differentiating knowledgeable scepticism from shit stirring, what you wrote wouldn't be well on the way to being a trope.

If you do go on them make sure you read up a lot more about it as tirzepatide is not insulin.

You’ve just proved my point with the name calling.

Thank you for proving my point. You might not like what OP has posted but she’s absolutely entitled to raise any question she wants to about WLI. Users do not have the monopoly on debating them.

There are plenty of medical studies highlighting new positives too. None of the medical studies that apparently highlight future issues have resulted in any change to the advice on WLI or the prescribing criteria from the MHRA.

Is there something about these medications that particular concerns you above and beyond any other relatively recent medication?

It’s not a “cult mentality” - it’s people getting - (rightly) pissed off at ignoramuses spouting easily debunked statements as “fact” when we - the people who have been taking them, have researched every bit of info about them and are effectively experts on them
know it’s a load of bollocks (there are threads on here every day going on about muscle wastage).

We just like to put you ignoramuses straight, that’s all 🤷‍♀️

You only have to google for about 10 seconds to find the information you need which is: all fast weight loss will cause muscle wastage and the onus is on the taker to do some weight lifting/exercise. It is much more dangerous to be an obese person who doesn’t exercise.

And if it turns out that scientists prove that there really is a risk from taking WLI’s (so far there is absolutely no evidence to suggest this - just it seems some very lazy journalism) il take my chances thanks!

I think there should be some kind of regulator who could balance the risks and benefits of drugs and decide the conditions under which they should be prescribed based on the sum of the evidence. Maybe a mumsnet Aibu poll?

It's becoming tedious seeing it claimed when people have made objectively not sensible posts.

Like OPs. This is an article broadly covering the positive impact of the drugs, and she started a thread based wholly on speculation. She then followed it by claiming that a post saying someone was concerned about the long term implications of the drugs without saying why was talking sense. When actually, that depends on what their concerns are.

Basically, yours is a point that would be better made if applied to a poster who's got something more useful to say than OP.

There are plenty of medical studies already highlighting issues, including the one I shared a few posts ago.

@HereforonedayonlytoavoidStrangerThingsspoilers I think if people had some kind of basis for thinking that there will be some as yet unknown long term issue they might be met with a reasonable response. But it just seems to be wishful crystal ball gazing rather than based on any kind of reasoned position.

It is “wheeled out” because it is becoming tedious the way anyone who dares to question the long term safety of these drugs is shot down on MN and attacked. I say that as someone who can see the positives of why people want to take them - it’s the cult mentality/don’t you dare question them mentality I find disturbing.

Yeah, do people really not get this?

@ThisTaupeZebra I’m not severely calorie restricted on WLI, it’s not an inevitable consequence although I’m sure some people experience that. Losing a lot of weight might not be benign. I don’t think that’s really an issue when you are already obese, which is most definitley not a benign position. It is a highly risky position to remain in. Losing weight via WLI is the overall less risky decision to make rather than remaining obese. I am overall healthier as a result and my risks of various serious health issues are massively reduced. So it’s a non issue for me, this idea that losing weight is somehow too problematic.