Please or to access all these features

AIBU?

Share your dilemmas and get honest opinions from other Mumsnetters.

Is Mounjaro magic or misery??

38 replies

CareerChange24 · 19/11/2025 14:52

I know there’s threads for new starters, but I’m looking for advice from those who have been on mounjaro and how they’ve found it.

Food is an addiction for me. Theres sympathy for alcoholics and drug addicts and anorexia. Much less so for those of us addicted to comfort eating. I’m 5’3 and 15 stones now. Getting the weight off is an absolute must now.

I have been on 2.5mg for the past three weeks and lost 12lbs without even trying. I feel nauseous and stomach ache and wiped out. I wanted to exercise alongside taking it but at the moment I couldn’t. I don’t have the energy I look ghostly and feel it.

Id love to hear the positives and negatives because im terrified of long term damage they could do. Also, when something feels too good to be true, theres that voice saying it probably is!

OP posts:
RhaenysRocks · 19/11/2025 17:21

showgirl · 19/11/2025 17:13

I have been on it for a year and have lost 30kgs still have a way to go. My hair is definitely thinner but I am also menopausal so it could be that. It can make me feel a bit icky sometimes and tired but I will take that. I am at my lowest weight for nearly 25 years. My blood pressure is almost perfect and my blood sugars are perfect now (was pre diabetic.) It has changed my life for the better.

I'd say the same. Been on it since April, lost slowly around 2.5 stone so far, not gone higher than 5mg. I've spent twenty five years going round the same cycle of gaining and losing a stone here and there, always creeping up and getting harder to lose. From day 1 this was just much easier to stick to whatever food I had planned. Not much in the way of side effects. OP I really recommend going and looking on the WLI boards and gave a read of one of the threads where people started a while back.

RhaenysRocks · 19/11/2025 17:18

JinglingtoChristmas · 19/11/2025 16:18

90% of people who stop taking it regain weight which is why many people accept it’s a drug for life.

90% of people who lose weight via any method tend to regain.

showgirl · 19/11/2025 17:13

I have been on it for a year and have lost 30kgs still have a way to go. My hair is definitely thinner but I am also menopausal so it could be that. It can make me feel a bit icky sometimes and tired but I will take that. I am at my lowest weight for nearly 25 years. My blood pressure is almost perfect and my blood sugars are perfect now (was pre diabetic.) It has changed my life for the better.

bridgetreilly · 19/11/2025 17:05

A friend of mine who has been on MJ since the beginning of the year recently had a heart attack. The doctors were very clear that the MJ was the best thing she could have done for her health, continued giving it to her in hospital, and sent her home with a full pen.

BelleEpoque27 · 19/11/2025 17:02

JinglingtoChristmas · 19/11/2025 16:18

90% of people who stop taking it regain weight which is why many people accept it’s a drug for life.

Oh yes, I know - but many people seem to be coming off it at the moment after losing a lot of weight in the past year or so.

If it works as well for me as many others I would be happy to stay on it forever, but the majority don't seem to be doing that (at least at the moment... probably mainly due to price).

IsThisLifeNow · 19/11/2025 16:22

its been great for me, 19 month in and I'm 70kg down, gone from a size 26 to a 16 and still losing. I've learned to control the side effects by making changed to my diet, which are healthier habits anyway so that's not a bad thing either.

I've lost all desire for fizzy drinks, which I used to drink a ton of too and stick to lower fat foods, as too much grease makes me nauseous anyway. I suffered terribly from dizziness for a while, till I realised I'd managed to lose my high blood pressure that I'd developed so I was able to stop my medication for that.

My plantar fasciitis has gone, I was in so much pain with that for a very long time and I'm so happy its gone. Ive been overweight my entore life, done all the slimming stuff, scottish slimmers, slimming world, keto, low fat, calorie counting, but this is the lowest weight I've been since I was probably 16 years old

JinglingtoChristmas · 19/11/2025 16:18

BelleEpoque27 · 19/11/2025 15:54

I am about to start (and terrified) and am interested to know, from those who have been overweight long term, lost weight and now come off... would you go back on if you needed to? Like most of us have been off and on WW, or SW, or calorie counting all our lives?

I can't imagine actually sorting out my weight problem and am wondering what life looks like if I do actually lose weight.

90% of people who stop taking it regain weight which is why many people accept it’s a drug for life.

JinglingtoChristmas · 19/11/2025 16:17

12pounds in 3 weeks is a lot. What are you eating? If you don’t each enough that can make you feel ill.

I would just stay on 2.5 mg for now.

GLP medication has been around for decades. We know MJ causes an increased risk of thyroid cancer but overall this level of increased risk of multiple types of cancer is less than risk of developing cancer if you’re being obese.

Ineedanewsofa · 19/11/2025 16:11

90% magic - 19 weeks in and 20kgs down, all on 2.5mg.
Some nausea and dizziness in the first 6 weeks but that subsided and hasn’t come back. A couple of bouts of fairly horrific constipation that did concern me but have adjusted diet and supplements and things are back to normal.
I am cold a lot of the time now and have lost some hair but I’ve always been a shedder!
My inflammation symptoms (tendon issues, carpal tunnel, bloating) vanished along with the nausea and have not returned. My blood pressure, HRV, resting heart rate and CVo2 max are all vastly improved. I am still drawn to healthier choices and feel full before the ens of a ‘normal’ portion. I’ll stay on 2.5 forever if I have to, hopefully it will get cheaper/microdosing will become more mainstream

BelleEpoque27 · 19/11/2025 15:54

I am about to start (and terrified) and am interested to know, from those who have been overweight long term, lost weight and now come off... would you go back on if you needed to? Like most of us have been off and on WW, or SW, or calorie counting all our lives?

I can't imagine actually sorting out my weight problem and am wondering what life looks like if I do actually lose weight.

HansHolbein · 19/11/2025 15:45

I would ask for this to be moved to the WLI section so that you get advice from people actually taking it.

FWIW, I’ve been on it 13 months, no issues or problems. 16st > 8st. Will be on it for life. Not concerned about it either.

crazeekat · 19/11/2025 15:15

5’3, 14 stone, comfort eater
all
My life. Lost 4 stone. Very happy. Blood pressure down, pain issues so much better, off meds.
it is difficult when u come off the eating does come back. U need to be really strict but u need to while u lose change the mind set. This is the key. Not the weight loss. The way I feel I would rather be skinnier and battle to keep weight off than be fat and battle to lose it. I will always have food and weight issues. But it’s managed so much better and mj gave me the tools to do it. I will never say bad about it as it has helped so many. Speak to ur gp.

incognitomummy · 19/11/2025 15:09

I lost on 2.5 as well but had no symptoms. So went up to 5 and then 7.5.

my only symptoms eventually were feeling cold and losing my hair.
i have lost 25% of me since Christmas (started MJ in Feb)

it is nothing short of magic. In terms of keeping me on track.

obvs stil need to not overeat but it makes that easier.

less snacking.
Drinking less.

Smaller portions.

I don’t think I would have stayed on it if I had felt sick. It’s just not worth ruining my day to day life.

But I was a size 16/14. I’m now a size 10.

perhaps if I had been morbidly obese I may have battled through sickness.

luckily I wasn’t and it wasn’t my experience.

best of luck to you.

Swipe left for the next trending thread