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AIBU?

Share your dilemmas and get honest opinions from other Mumsnetters.

To have turned down Munjaro?

136 replies

Uberella · 13/05/2025 19:32

In 2020 I was diagnosed with type two diabetes;I have since then lost 6st in weight to try to help;I was huge at 5ft 4in and a whooping 22st 10lbs.

Roll on now;unfortunately despite my weight loss I’m really struggling with my diabetes at the moment;My blood sugars are really high even when I’m not touched anything sugary.

I’m currently on insulin and statins for high cholesterol.I’ve been told multiple times in the last few months I’m at risk of early death.

which is why I’m wondering if I was right today to have turned down munjaro jabs when offered them during a routine treatment review today.

I know I need to lose more weight;I’ve been doing slimming on and off for a few years but I’m terrified of the munjaro jabs;I know people who have suffered terrible side effects from these jabs plus weight gain after stopping the jabs and I’m not liking the things I’m hearing in the media about it.

I saw another pharmacist at my GP surgery a few months ago that I don’t normally see and he said to me that he doesn’t personally recommend Munjaro as there is evidence it causes hepatitis.

OP posts:
BoredZelda · 15/05/2025 08:44

Ceska · 13/05/2025 20:14

pharmacist

(And you don't need to quote the op....)

Sure, whatever, you knew what I meant, clearly (And I’ll post how I like, I think I’ll quote the OP more, knowing how much it bothers you….)

ElaineBurdock · 14/05/2025 21:36

Many pharmacist have not studied up on Mounjaro and Zepbound as they are fairly new medications. Our small town pharmacist, who's been a pharmacist for 30 years, didn't understand the drug fully when I chatted to him about it, but he's learning.

I get my Zepbound from LillyDirect self-pay for $500/month, through a Telehealth clinic.

WiddlinDiddlin · 14/05/2025 21:15

Bluntly, yes thats daft.

Im on Ozempic, but they all do basically the same thing, these jabs will reduce the amount of insulin you need to take because they improve how you respond/reduce how much you need.

I've cut the amount of fast acting insulin I take by two thirds! Some days, more than.

That has had a significant effect, meaning I can eat more fruit/veg and have a healthier diet.

Talk to your Diabetes nurse again. Ignore what silly people say, these drugs were designed first and foremost for diabetes control/management!

IncessantNameChanger · 14/05/2025 21:13

I keep on creeping near the pre diabetic range and I have just started monjaro. But I'm doing fasting and have been on and off for around two years. During the week I don't eat anything from 9pm until 1pm the next day. I test my blood sugars at home and this has kept my sugars vert stable.

Weirdly the less I eat, the less I feel hungry. My brain was telling me I felt sick, I felt dizzy. But I'm not not. After a few weeks I honestly don't even feel hungry by 1pm.

I eat as I feel at the weekend.

Have you got a blood sugar app? I find the that was very insightful and I do my finger tricks in my thigh as it hurts less and gave the same readings as my fingers.

OrlandointheWilderness · 14/05/2025 21:04

Oh I’ve been on it since October. Lost 5 stone, feel fab and barring the odd bit of nausea no ill effects.

OrlandointheWilderness · 14/05/2025 21:03

Good on you for researching - but make sure you don’t just do opinion papers but actually read the published peer reviewed studies. You can find most of them on PubMed.
and while you are at it I urge you to properly research the consequences of your uncontrolled diabetes… there is a tiny tiny risk with MJ (as any meds) but an almost certainty that your diabetes will cause you awful effects. I’ve seen it - it’s not nice at all.

testest · 14/05/2025 16:42

OP - I have diabetes (on insulin) and am overweight. I don’t eat much and for a while refused ozempic because I didn’t need appetite suppression (my dr said that my insulin resistance was my main problem which was making it hard to control my blood sugar and lose weight).

My dr convinced me to try Mounjaro as it targets insulin resistance, inflammation- not just appetite suppression. At first I wasn’t sure as 2.5ml and 5ml doses made no difference to my blood sugar. However moving up to 7.5ml and 10ml has been a game changer, my hba1c has gone down and I’ve lost 10kg.

I think it’s worth a try

BethDuttonYeHaw · 14/05/2025 15:04

I’d rather take mounjaro than insulin and statins.

i recommend you read some of the many threads on here about it. That way you will hear real stories from real people rather than the clickbait dramas in the daily Mail and the like.

personally I’ve lost 4.5 stone over 8 months at roughly 1-2 lbs per week. I really don’t have any bad symptoms other than being a bit burpy for a fee days each week.

putting weight back on after any diet is a risk - you can put it back on after weight watchers and slimming world but that hasn’t stopped you so why the fear with mounjaro?

as for causing hepatitis - that’s just bollocks

mondaytosunday · 14/05/2025 14:57

I’d go in MJ in a nanosecond but I have type 1 diabetes and it’s not approved for that. I think the benefits far outweigh the risks.

untilido · 14/05/2025 14:31

Uberella · 14/05/2025 10:06

I want to thank everyone who has taken the time to reply with helpful suggestions and to share their own experiences;You’ve given me podcasts to listen to,literature to read and things to research.

To those ridiculing the lovely pharmacist from my GP surgery (not some member of boots staff as someone suggested) shame on you;my daughters close friend is a third year pharmacy student, pharmacists go through four years of university, do hours of placements in hospitals like other medical professionals and have extensive medical knowledge.Medication can cause liver inflammation and mounjaro is a medication.

I have a telephone review with the pharmacist (who deals with my diabetes reviews) in 3 weeks so If I change my mind I can request a prescription for mounjaro then.I’d say 3 weeks is long enough to do some reading on it.

‘Shame on you’ - really? I don’t need to be shamed for suggesting that the pharmacist was batshit. He absolutely was. Of all the potential side effects and complications of Mounjaro hepatitis isn’t up there. It’s a miniscule risk in comparison with all the others and when you balance it over the health benefits it really does become even smaller.

If the pharmacist had listed possible complications and hepatitis was one of them, fair enough. But to suggest you should not take it due to a risk of hepatitis definitely was batshit. So shame the idiotic man who told you that, not the people who are sensible enough to consider all aspects of the drug.

Wonkypictureframe · 14/05/2025 14:17

I'm really pleased you feel this thread has provided good research material.

The many posters on MN who are 'concerned' about the side effects/long term outcomes for fat people taking it often also say that it's a diabetes drug (and presumably think that then none of those effects are relevant for them). It's sad that they may be putting you off accessing an effective medication - for weight loss and blood sugar control.

Your pharmacist's advice is also a bit worrying - hepatitis is NOT a common side effect of Mounjaro and for him to be deterring people from it on that basis who could benefit enormously from it is questionable. It should be an informed balance of risks and not skewed like that. There have been some reports of people with raised liver enzymes on MJ but nothing that is causing serious concern and the effects appear to be totally reversible. This article is quite good - I can't vouch for Diabetes Magic as a website but he is citing scientific articles.

Can Mounjaro Cause Elevated Liver Enzymes? - Diabetes Magic

Can Mounjaro Cause Elevated Liver Enzymes

Can Mounjaro Cause Elevated Liver Enzymes? - Diabetes Magic

Yes, Mounjaro can cause elevated liver enzymes in some patients. However, this risk is relatively low and reversible.

https://diabetesmagic.com/can-mounjaro-cause-elevated-liver-enzymes/

Crikeyalmighty · 14/05/2025 14:01

@Moooooooooooooooooo. I had very weak feeling legs on statins- had to cut down to 2 a week to get rid of that and not at a high dose either ( which apparently is still
much better than none) not a great feeling -

a GP friend told me that whilst statins are very useful for cholesterol levels and de rigeur if you have had a stroke or coronary event - they work better on males and women under 50 and aren’t necessarily that effective on women over50 with only cholesterol Asa problem and better trying to get it down on its own with different diet, quit smoking if applicable and a bit more excercise

Moooooooooooooooooo · 14/05/2025 13:19

No-one mentioning the side effects of statins? Look them up.

AmythestBangle · 14/05/2025 12:43

It's not a "new drug".

21ZIGGY · 14/05/2025 12:33

2024onwardsandup · 13/05/2025 19:37

Hepatitis 😂

Exactly🤣

Op, you can make any decision that you want for yourself. But you knew that.

fatttyfatfat · 14/05/2025 12:32

Are the recommending it for weight loss, or are they recommending it because it helps with insulin production? If it's the second I'd be more inclined to go for it- yes these jabs are great for weight loss but that wasn't why they were originally created

HuskyNew · 14/05/2025 12:00

It seems mad to me that you’ll take statins and insulin, but not mounjaro based on …. Not quite sure what, media hype?

have you looked at the side effects of statins?

and the side effects of uncontrolled blood glucose?

mounjaro is a safe & effective treatment for many, in your case the benefits far outweigh the risks.

Tiredb · 14/05/2025 11:45

Uberella · 13/05/2025 19:32

In 2020 I was diagnosed with type two diabetes;I have since then lost 6st in weight to try to help;I was huge at 5ft 4in and a whooping 22st 10lbs.

Roll on now;unfortunately despite my weight loss I’m really struggling with my diabetes at the moment;My blood sugars are really high even when I’m not touched anything sugary.

I’m currently on insulin and statins for high cholesterol.I’ve been told multiple times in the last few months I’m at risk of early death.

which is why I’m wondering if I was right today to have turned down munjaro jabs when offered them during a routine treatment review today.

I know I need to lose more weight;I’ve been doing slimming on and off for a few years but I’m terrified of the munjaro jabs;I know people who have suffered terrible side effects from these jabs plus weight gain after stopping the jabs and I’m not liking the things I’m hearing in the media about it.

I saw another pharmacist at my GP surgery a few months ago that I don’t normally see and he said to me that he doesn’t personally recommend Munjaro as there is evidence it causes hepatitis.

The value in GLP1 drugs isn't just in weight loss.

There are massive clinical trials showing they significantly improve diabetic control, reduce chronic kidney disease, and protect against stroke and cardiovascular events including heart failure. It is a standard part of care to offer these drugs to patients like you with risk factors.

They've been used in diabetic care for many years (at least 10 years)

Serious side effects are rare and you need to balance the more common side effects against a significant long term benefit to your health

PiggyPigalle · 14/05/2025 11:01

Uberella · 14/05/2025 10:06

I want to thank everyone who has taken the time to reply with helpful suggestions and to share their own experiences;You’ve given me podcasts to listen to,literature to read and things to research.

To those ridiculing the lovely pharmacist from my GP surgery (not some member of boots staff as someone suggested) shame on you;my daughters close friend is a third year pharmacy student, pharmacists go through four years of university, do hours of placements in hospitals like other medical professionals and have extensive medical knowledge.Medication can cause liver inflammation and mounjaro is a medication.

I have a telephone review with the pharmacist (who deals with my diabetes reviews) in 3 weeks so If I change my mind I can request a prescription for mounjaro then.I’d say 3 weeks is long enough to do some reading on it.

Pharmacists aren't infallible.
Neither one High St and the other a hospital pharmacist knew that Vit K2 should be taken with Vit D3. They both checked on their computer to find it was correct.

Nor have they recommended Vit B12 to patients taking Omeprazole, which would have saved many from the bad side effects resulting from the drug.

As to your original question, if you want to discuss with more people who actually take it for Diabetes, rather than weight loss only. People are sharing their experiences of taking Mounjaro on Diabetes UK.

Anyotherdude · 14/05/2025 11:00

My relative is type 2, Mounjaro has been wonderful for them so far - it really helps with keeping glucose spikes down. They wear a cgm, so you can see the difference it has made to them in the few weeks they’ve been using it along with Insulin

dottydodah · 14/05/2025 10:51

Firstly well done on weight loss.I read somewhere that pancreaitis and gallstone issues can be caused by MJ .maybe rare though .If you are not happy with these injections I would carry on losing weight as you are .You have done well to lose so much.

BurBurBarBar · 14/05/2025 10:49

I had prediabetes and lost 5 stone over the last few years. I'd have taken weight loss injections if they were around at the start but by the time they rolled out I wouldn't have been prescribed them.

I was a couch potato eating and drinking lots of crap, and started off cutting out junk and calories generally, and started running and then doing weight training. I gradually increased the running and moved onto a high protein diet I track with a fitness app.

I now run or work out 5/6 times a week and while I occasionally give myself a holiday from nutrition tracking I do it most days. I've joined a running club and a gym I really like, and get advice from a PT. It's sometimes tricky balancing this around the kids and work and means some early starts to fit in exercise, and tbh some other things I enjoy have slid a bit.

My BMI is now in the middle of the healthy range.

I think what I'm saying is that it can be done but it takes a lot of effort, time, some expense and continuous lifestyle changes; i couldn't have leapt straight into what I do now but it was a process over a few years of tightening things up and getting better advice. And also realising these changes were permanent.

I guess a lot of it comes down to wanting to improve your health and weighing up whether you're going to be able to go further on diet and weight (and well done on losing 6 stones, that's amazing!) or whether the jabs will be more effective.

mumuseli · 14/05/2025 10:12

I admit I'm not very knowledgable on this, but wasn't the original purpose of these jabs to help those with diabetes? So they could be ideal for you. Good luck. x

Uberella · 14/05/2025 10:06

I want to thank everyone who has taken the time to reply with helpful suggestions and to share their own experiences;You’ve given me podcasts to listen to,literature to read and things to research.

To those ridiculing the lovely pharmacist from my GP surgery (not some member of boots staff as someone suggested) shame on you;my daughters close friend is a third year pharmacy student, pharmacists go through four years of university, do hours of placements in hospitals like other medical professionals and have extensive medical knowledge.Medication can cause liver inflammation and mounjaro is a medication.

I have a telephone review with the pharmacist (who deals with my diabetes reviews) in 3 weeks so If I change my mind I can request a prescription for mounjaro then.I’d say 3 weeks is long enough to do some reading on it.

OP posts: