To have turned down Munjaro?

Agreed. The ‘hilarity’ is making me cringe. Many things can cause liver inflammation. I expect many people are thinking about Hep B etc.

@AccidentalPrawnYouFool there was a useful post earlier in the thread, where it was pointed out that hepatitis just means a liver inflammation. Many people associate the term with viral liver diseases, but they're not the only cause.

So, Mounjaro could cause liver inflammation, but it wasn't reported in any of the research trials. There's one possible case that has been written up, so it may be an extremely rare side effect. Or it may have been unrelated to the Mounjaro. Either way, it is odd for a pharmacist to warn someone off an appropriate medication for their condition by mentioning a possible and/or extremely rare complication.

I see the thread has moved on! Apologies. Congrats on your immense first week loss @Uberella!!!

Hepatitis? Did the pharmacist mean pancreatitis?

YANBU to turn it down but there’s a lot of fear mongering. In my opinion being obese has far more health risks than taking a medication for a short period.

Good for you - are you pleased with that? I know I would be.

How are the side effects now after your 2nd jab?

I found they were worse on the lowest dose right at the start and had a little blip (burps and farts - although the farts were not smelly) on the 2nd day after each injection. I have now just ordered my 4th pen I have gone up a dose each month and rarely any burps and farts now - will take 10mg tomorrow.

I have lost 2st 4lb whicg has knocked 6 points off my BMI.

I am doing intermittent fasting, one meal a day (as my metabolism is knackered due to meno, yo-yo dieting and hypo thyroidism) and low carb - this has stripped belly fat - my arms and legs are still fat but my abdomen is now flat - this tells me that I am not losing muscle and bone.

Well done on accessing and reading up on the science to weigh up the cost/benefit to you personally.

Do you have any interim goals and rewards for those goals?

@NoVibrato I am on statins but will only take half a dose 3 times a week - this still has some effect , but I found taking it every day at full dose gave me really weak legs and arms and I felt lousy -and I’ve been on 2 different types with same effect .

I'm 2lb away from losing 3 stone since last week of February.

I make sure I drink 3ltrs of water a day. I've found chia seeds to be a massive help to keep me regular lol and try and hit your protien goals every day.

Heard some baseless scaremongering stories on the radio today, but I'd like to delve more into them as I highly doubt the reason 6 people have died is due to MJ.

I also think that people with issues from it, are not looking after themselves properly whilst using it (i.e. not drinking enough water, eating shite, under eating)

Furthermore, there seems to be some evidence that statins can actually help to create the metabolic conditions in which type 2 diabetes emerges.

Welcome to the club OP! And yes they almost certainly will settle after a day or two. Pepto bismol is your friend.

I’d check her medical credentials. 😂

Are you sure it was hepatitis and not pancreatitis? Mounjaro/Ozempic do increase the risk of pancreatitis, and there is evidence of elevated risk for several other conditions (including macular degeneration). All drugs have risks, it’s a matter of balancing the risks against the benefits. If people are a relatively healthy weight, the risks should give them pause if they’re thinking of taking the drugs as an easy way to drop some weight (which a close friend told me they were thinking of doing). But the risks of the drugs are very small compared with the risks of obesity and uncontrolled diabetes.

Mounjaro was successfully used to treat diabetes long before the weightloss benefits came to light. In your shoes especially knowing you would like to loose more weight I would jump at it. I am paying privately for it as a treatment for obesity and have lost 3 stone since October and I am half way to my goal. It is life changing or me. I have lost weight slowly compared to some which I hope will help me keep it off. I don’t think you are more likely to put it back after mounjaro than any other diet. The side effects have been very manageable for me. A bit if nausea, bloating, indigestion. Pepto bismol or peptac settles it. The two worst times were after eating chinese takeaway and dominoes so I think a lot of people who suffer do so because of what they eat, although some are just unlucky. Do your research. Don’t dismiss it out of hand. All meds have risks but so does being obese or struggling to control your blood sugar.

I’d go for it. I’ve had zero side effects. lost 2 and half stone and it’s been life changing. I no longer hate my reflection. My clothes fit again
I don’t cry to myself. I can walk, bend, move everything is better.

I do think there are a lot of scare stories in the Press about MJ side effects. It put me off for quite a while but then once I started to do my own reading, I was pretty surprised. I’ve been on MJ for nearly 6 weeks and have lost 11lbs. I’ve had some minor side effects such as heart burn and constipation but it’s all been very treatable with over the counter stuff.

It’s been the easiest thing I’ve ever done. I’ve overhauled my diet and now find myself actually craving vegetables (unheard of for me!) and even when I’m hungry, I still find it really easy to choose good foods rather than fall face first into a takeaway. I can cook for others and not feel the need to eat it. I can go to a BBQ and be really content with having one burger and not need to hoover up potato salad, crisps, dessert and wine. For many, it’s a life-changing drug which buys them time to ‘reset’ their relationship with food. Of course I’m already thinking about what it looks like when I get to my goal weight but I’ve still got 5 stone to lose so I’m just focusing now on developing a taste for good, wholesome food and not some of the rubbish I used to eat.

I pay for it (as I imagine many do) but it’s worth every penny.

In your situation and especially with the warnings about your health, have a good read and give it some serious consideration. It’s obviously your decision but for me, I’m so, so glad I did it.

There is no evidence of this, so far as I'm aware, unless people are sharing needles?

I was at a cosmetic clinic the other day, getting some fillers for marionette lines which have become a problem since my weight loss on MJ. The person doing the procedures was a doctor. She had never heard of MJ, when I mentioned I has lost weight on it she said "what's that?". I have to say I lost some confidence in her.

OP I tend to be quite conservative about medicating, and especially newer drugs and uses. But in your case it seems to me that your risks from your weight are much greater than from taking the drug.

I would be worried about gaining later and I think you will need a good plan to deal with that.

I do think you are being unreasonable not to try it, seeing as you are still overweight (despite a previous fantastic loss which you should obvs be very proud of achieving) and still struggling to get your diabetes under control.

I lost 4.5 stone with Mounjaro (from BMI 30 to BMI 20) and it’s like losing 15 years of aging. Back at the gym 6 days a week, cycling for transport and dancing for fun. This time last year just climbing the stairs made my knees hurts.

Side effects have been extremely minimal for me, but if they had been difficult (as they are for some people) I would’ve just stopped or switched to one of the other injection types to see if they were more tolerable.

I really cannot express how sincerely I feel that Mounjaro has given me my life back.

Out of interest, are you seeing people with panic attacks and racing heart? That was my experience - day after the jab woke in the early hours, heart rate 140, absolute rolling panic up and down my spine. Continued for 3 days and even if you paid me £1000 I wouldn't take it again. Threw the pen away!

And it was from Voy so definitely not a dodgy back Street dealer.

I don’t have any side affects, just weight loss and all the health benefits shots that go with it. Listen to Dr Tyne’s podcast. Most of the scaremongering isn’t factual. All rapid weight loss can potentially cause these same health issues. The key is slow steady loss and Mounjaro can really help you achieve that while also helping with your blood sugar issues. My dad suffered seriously with his diabetes and the suffering I saw before he died of diabetes related health issues was horrendous. I’d rather have Mounjaro’s worst side affects than that.

Speak to health professionals who know about glps and don’t have a vested interest in keeping you fat and sick (like big sugar who are putting many of the scare stories out there!)

The reason people are ridiculing him/her is because the information they gave you is completely inaccurate and illustrates the fact that they know nothing about it and they're not in a position to recommend or otherwise as their information is wrong.

Mounjaro can causevpancreatitis (which has nothing to do with your liver apart from it being in the same area of the body) in mice. It is contraindicated in people with gall bladder problems, again nothing to do with the liver apart from it's general location.

That is the reason people are shaking their heads at the pharmacist, who unfortunately needs to do some reading before running their mouth with incorrect information.

I was taking MJ for a few months but despite being morbidly obese have stopped taking it. I am not diabetic. My main concern is that I feel like my eyesight has deteriorated and obviously that's not something I want to risk further. Also has awful diarrhea and nausea.

Yes some (not all) are taking it inappropriately, which muddies the waters.
If a person is concerned about the real (as opposed to fake stuff on social media), known, and serious side effects of a new drug, I would never try to persuade them to take that drug. They’re telling you that if they got those serious side effects, it would not have been worth it for them.
It’s an amazing drug, but it’s one treatment amongst many and it’s not for everyone.