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Original poster

Sertraline 14 days positive stories please

169 replies

Francis24 · 23/04/2025 13:25

How long before sertraline made you start to feel better depression? I've been taking it 14 days 25mg positive stories please

OP posts:
ColdTofuSandwich · 01/05/2025 13:39

Couple of hours maybe? Much better if I get up as soon as I wake up - if I go back to sleep it’s harder to get going

Original poster
Francis24 · 01/05/2025 13:28

ColdTofuSandwich · 01/05/2025 12:26

But two weeks on 150mg dose

How soon after the morning does it pass for you?

OP posts:
Original poster
Francis24 · 01/05/2025 13:09

abracadabra1980 · 01/05/2025 12:34

Sertraline was a life saver for me - started on 50mg then upped to 100mg. The first 2/3 weeks are pretty rough but stick with it, you're through the worst now. Good luck X

Thank you for this xx😊

OP posts:
abracadabra1980 · 01/05/2025 12:34

Sertraline was a life saver for me - started on 50mg then upped to 100mg. The first 2/3 weeks are pretty rough but stick with it, you're through the worst now. Good luck X

WhereIsMyJumper · 01/05/2025 12:29

Not sertraline but I was on another SSRI. I was lucky in that the negative effects in the first weeks were minimal. I remember about week three all of a sudden having a positive thought pop in to my head. Like everything was going to be ok, so I think that’s when I first started feeling better. Then started feeling better and better and peaked around 3 months.
I came off them a year later with no ill effects and haven’t needed them since. Good luck.

ColdTofuSandwich · 01/05/2025 12:26

But two weeks on 150mg dose

ColdTofuSandwich · 01/05/2025 12:25

I have changed my meds to sertraline so am slightly different to you. I’m on 150mg and 8 weeks in.

Original poster
Francis24 · 01/05/2025 11:31

ColdTofuSandwich · 01/05/2025 10:31

Yes exactly that. I felt better of an evening - not 100% but better, and that feeling gradually gets earlier in the day. I’m a good 10 days into that at the moment and I’m still struggling in the morning but it does pass quite quickly

What dosage are you on and for how long?

OP posts:
ColdTofuSandwich · 01/05/2025 10:31

Yes exactly that. I felt better of an evening - not 100% but better, and that feeling gradually gets earlier in the day. I’m a good 10 days into that at the moment and I’m still struggling in the morning but it does pass quite quickly

Original poster
Francis24 · 01/05/2025 10:07

Hankunamatata · 30/04/2025 20:39

Hang on there. 50mg is my maintenance dose qnd has been for years. I'm just not a nice person without it. Times of high stress I move to 100mg for a period. Obviously with doctors permission

Thank you x

OP posts:
Original poster
Francis24 · 01/05/2025 10:07

NippyNinjaCrab · 30/04/2025 20:52

Keep hanging on lady, one day the low just won't seem as black and bleak. Hugs xx

Thank you x

OP posts:
Original poster
Francis24 · 01/05/2025 10:07

Hillsmakeyoustrong · 30/04/2025 21:03

Cortisol levels are at their highest in the morning (so I was told!) and my anxiety was always raging in the mornings. But also when are you taking the tablet? Morning or evening?

Hello 👋 in the morning, around 8am as I was sleeping at all before. Is it better to take at nighttime for morning anxiety?x

OP posts:
Original poster
Francis24 · 01/05/2025 10:06

ColdTofuSandwich · 01/05/2025 00:16

i know I’m getting better when it lifts in an evening. That will hopefully get gradually earlier as the medication takes effect

Thank you. So when you were getting better, did it start more on an evening? Did it eventually get earlier in the day too?

OP posts:
ColdTofuSandwich · 01/05/2025 00:16

i know I’m getting better when it lifts in an evening. That will hopefully get gradually earlier as the medication takes effect

Hillsmakeyoustrong · 30/04/2025 21:03

Cortisol levels are at their highest in the morning (so I was told!) and my anxiety was always raging in the mornings. But also when are you taking the tablet? Morning or evening?

NippyNinjaCrab · 30/04/2025 20:52

Keep hanging on lady, one day the low just won't seem as black and bleak. Hugs xx

Hankunamatata · 30/04/2025 20:39

Hang on there. 50mg is my maintenance dose qnd has been for years. I'm just not a nice person without it. Times of high stress I move to 100mg for a period. Obviously with doctors permission

Original poster
Francis24 · 30/04/2025 20:29

Hillsmakeyoustrong · 30/04/2025 20:18

Thinking of you @Francis24 x

Aw thank you x
I'm feeling a lot better tonight. I feel like a different person on an evening since Saturday. It is the morning and day time which is bad still. I'm hoping that will improve soon. The evenings are so different!
Thank you so much and hope you're ok xx

OP posts:
Hillsmakeyoustrong · 30/04/2025 20:18

Thinking of you @Francis24 x

Original poster
Francis24 · 29/04/2025 09:33

NippyNinjaCrab · 29/04/2025 09:23

Morning @Francis24 how you feeling? X

Hello, not great tbh. Feel very depressed and low and not myself at all. 5th day on 50mg. First week 25mg. Thanks for asking x

OP posts:
NippyNinjaCrab · 29/04/2025 09:23

Morning @Francis24 how you feeling? X

vincettenoir · 28/04/2025 17:37

Moomoo75 · 28/04/2025 13:48

Did anyone notice the gained weight on it?

Not me

Moomoo75 · 28/04/2025 13:48

Did anyone notice the gained weight on it?

Jumpingthruhoops · 28/04/2025 02:39

whatisforteamum · 26/04/2025 10:44

Did anyone take anti sickness

I took Lorazepam. Which I didn't actually realise is often prescribed as an anti-sickness med to those undergoing chemotherapy for cancer.

Jumpingthruhoops · 28/04/2025 02:31

Skade · 26/04/2025 07:29

I’m on 50mg and definitely remember starting to feel better after 3/4 weeks. I tried going up to 100mg but lost the ability to orgasm (libido was not affected!) almost overnight which I couldn’t tolerate, so went back down to 50mg which seems to be the sweet spot for me.

I experienced this and found that not taking my med on the day that there's a high chance of 'DTD' and I'd have no bedroom issues at all. Missing one day doesn't impact negatively on my mental health, so it's worth it.
Of course everybody is different though, so do consult your GP before contemplating this.

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