I want to try mounjaro

They have, but it's rare and usually as a consequence of getting a dodgy supply from an unregulated seller, or because they did what some people have done here and 'fiddled' their weight or not told the pharmacy about certain health conditions that they have, that would make them unsuitable for the drug. If it was that dangerous when prescribed correctly to suitable people, I doubt it would be available from online pharmacies.

I've just ordered my first dose, my GP has referred me to weight loss clinic (BMI 39 with high bp and sleep apnoea) but it could be a long wait so I would like to try it while I wait.
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I had to submit a video of myself getting onto the scales so that they could see the weight shown was actually me. Plus I have to have a video consultation. Plus photo ID and all the health questions you have to answer beforehand, it seems very thorough.

Private doctors are prescribing to those such as Olivia Falcon who don’t meet official guidelines and a healthy BMI at least now & seemingly before. She explained sudden weight gain in menopause etc. Regular blood tests etc as safety mechanism plus medical supervision Interviewed on TV & seemingly positive response. Seems from what you say this is potentially playing roulette with health? At least until we know much more & not something to do lightly.

Like any medication, WLI come with risks - pancreatitis for eg being one of the most written about. The risk of taking the medication, as with any medication, has to be weighed up against the risk of not taking it.
The MHRA have seemed that risk, on balance, as worthwhile for someone who is obese and therefore has risk to their health from obesity. The risk is not deemed worth it for someone of a healthy weight. Bluntly an obese person might die because of their weight, a person with a healthy BMI won't.
Thet doesn't mean that the jabs are more dangerous necessarily for someone of a healthy weight but it's unknown as medical trials haven't been run.
I don't believe microdosing has been approved, or trialed, but is a way some people are going off menu. Again, that may not be any more dangerous that taking the prescribed doses but it too is unknown as trials haven't been run.

I hear you but I keep hearing about this disproportionate ‘danger’ for some, which doesn’t feel always logical & there are those who appear to be legally & medically sanctioned to ‘micro dose’ too. No doubt we’ll see all sorts of positive help/advances in time for broader categories.

I don't set the licensing guidelines 🤷🏻‍♀️ The folks who do though have assessed the risks and benefits and decided the criteria. It's not about what's fair, it's about the assessed licensing of a prescription medication for a disease.

Fascinating!

Any weight loss in any form comprises losing muscle mass & fat surely? The gym & right food can mitigate muscle loss.

Quite & hear you on quick fix but a body that just meets threshold isn’t same as one morbidly obese for decades surely? If someone is happily now mid healthy BMI for months but not yet at target this is fine?

Yes that sounds plausible. I'm worried about messing my body up even more. But carrying on as I am which isn't working also not a good option.

My worry with these drugs is that yes, your body will lose weight, but the weight will be composed of fat plus muscle mass. Then when you come off it, your metabolism will be in a worse state meaning you need to eat even less than before in order to maintain.

I have an underlying condition and have been prescribed it. Hence the dilemma. Honestly just trying to get some experiences to help me decide what to do.

You won't get it at BMI 28 either unless you have an underlying condition.

Lots of us who are BMI 28 have tried hard to lose weight for many years also, 15 years for me. I used to be BMI 19 before having kids.

Because a body that has been obese and is now a healthy weight doesn't behave in the same way as a body that's always been a healthy weight. The former is far more likely to become obese again.
It is medication designed to treat obesity, which includes maintenance, and not a quick fix to treat wanting to lose a few pounds before the summer.

There are many on here still on MJ etc with healthy BMI but not yet at goal, who started out overweight/obese. Why is this ok and not as or more ‘dangerous’ than someone theoretically on it who marginally misses overweight threshold criteria?

I am also concerned about gaining back after I stop so am trying to educate myself about the biochemistry of fat cells.

I heard/read something somewhere that in order to keep the weight off, you need to keep it off for at least 2 years (maybe it was 5!) because after this point the body gets rid of the fat cells rather than just emptying them out (to put it crudely).

From Oprah magazine:
When we quickly put on a lot of pounds in early childhood, at puberty, and sometimes even as adults, we can grow new fat cells. Known as hyperplastic obesity, it poses a daunting challenge. The only way to be thin if you have an excessive population of fat cells is to shrink them below normal size, which is where things get really tough. The cells begin to produce less leptin, a hormone that signals the brain when you're full. You'll end up feeling ravenous all the time. If you find the will to lose more than 10 percent of your body weight (more than 20 pounds for someone who weighs 200), eventually you'll induce a process called apoptosis—cell death. You could begin trimming your population of fat cells. Once you do, you'll find that maintaining a lower weight gets easier.

I'm currently taking mounjaro and I have CONSTANT food noise. Constantly starving, always thinking about food.
I'm loosing weight but it might not be the magic cure you think it is.
I have also shat myself. Multiple times. (Unpleasant side effects)

Don't bother tried it for six months, watched what I ate, went to the gym twice a week and it made no difference. Snake oil

I don't regret it at all. It's been life changing.

I plan to taper slowly down the doses before stopping and will do that v v slowly. I also plan to increase my running as I decrease my doses. So by the time I stop I'm running a decent mileage every week and working towards longer and longer distance events.

I can relate OP. I had a moment of desperation and applied for some on Superdrug. No judgement for anyone using it but I'm scared of the side effects and what happens after.

I'm not obese but my BMI is over 28 and I've got health conditions that make me eligible so they're on they're way to me. I half hoped they'd turn down my application so I tthought I'll be completely honest about my stats etc and let fate decide. But I'm freaking out now as all the data says once you come off your hunger is out of control (like after any really restrictive diet) and you gain all the weighted back and then some. I'm pretty scared of that having experiencd similar in the past when I've been too restrictive.

I definitely wouldn't want to be on it for life which seems to be what you're signing up for with it. I really need to lose some weight to look after my health but find it almost impossible due to peri menopause, emotional/boredom eating and general exhaustion of having a young family.

I generally eat pretty healthily and try to exercise 3 times a week but it's not enough. I'm going to give it another shot at exercise and trying to get a calorie deficit before I consider using it. Feels like it's signing a contract with the devil almost.

Does anyone in a similar position regret every starting on it?

I agree. Then there is that thing on Tik Tock making people look fatter in photos. Perfect for this I suppose. There have always been people willing to go to lengths to harm themselves in order to lose weight.

@MjStartsToday It’s great that it’s worked for you but that’s you not the OP just because you’ve been fine doesn’t necessarily mean that it will work for someone else though and they’ll be fine. How would you feel if someone read your comment and thought l’ll do the same thing and fudge my numbers it won’t matter and ended up dying. Think before you say something because you don’t who is reading these comments. It’s a dangerous drug with serious side effects and it’s better if your being monitored while your using it.

I would like to hope so but I know people are getting it online from “doctors” someone even said to fudge their numbers to get it because that’s what they did.

Possibly. But we already know many of the myriad dangers of being overweight- which is going to be the bigger problem? I actually think these drugs are going be a game changer for the NHS (in a good way).

I've lost a couple of stone, but more importantly, when I had a blood test in January all of my blood markers had improved, some significantly. My GP actually sounded amazed at how much better my cholesterol levels were! I had also gone from being pre-diabetic to being fine. Liver function improved as well, I could go on.....oh my blood pressure is also down to a healthy level, after years of taking medication for it.

I’m pretty sure she means buy online from a pharmacy.