to think more negative effects will come out from Ozempic use?

Im pretty worried at the moment about the number of women i know who have spoken openly about being able to get it online, with BMIs between 25& 28, having provided no evidence of their actual weight. I know its proven to have real benefits (outweighing side effects) in those who are obese, and have no issue with it in that medical context, but its more than just the obese who are taking it. I'm hoping a bit tighter regulation will come in before nasty side effects do emerge

I agree to an extent because these drugs haven't been tested much on people who are merely overweight not obese or diabetic, yet people are using them who really shouldn't be based on clinical need. Also, some users are saying they intend to follow a "maintenance dose" for life and the long term effects of continuing to take it when you're no longer obese and for so long have not been studied. The NHS only recommends it for up to 2 years at present.

On the other hand, the example that @nameey posted was not a good one as that person obviously made a lot of bad decisions around taking the drug, eg, she didn't need it for her weight and she didn't use a reputable pharmacy. I think a lot of positive things will come out of Ozempic where used correctly as there are potentially a lot of health benefits in losing weight. But I do worry that there will be some negative consequences too. If I were using it (and I did try it but it didn't agree with me), I would use a reputable pharmacist and only take it for up to the recommended 2 years.

We'll see more and more of these cases its simple stats. Million to one chances happen more than 60 times a day in the UK - simply because of the # of poeple.

My cardiologist was very impressed with my mj weight loss

Agree! It's v weird. I guess they can't think themselves superior for being slim anymore, if everyone is slim

I listened to a doctor who said we will start seeing some of the rarer serious side effects with Ozempic and similar, mainly because more people are taking them.

If there is a 1 in 100,000 chance of x side effect, the more people take it means the more cases of the rare side effect you will see.

It doesn't mean the drug is more dangerous that it was before, it's pure statistics.

A huge issue at the moment is the control of the drug and stopping people taking it who shouldn't be.

"I want to make it clear that I do have an eating disorder and did NOT get Ozempic from a doctor."

I am pretty sure I could also make myself very unwell by illegally obtaining drugs I do not meet the qualifying criteria for. This is not a warning case against Ozempic, it's a warning case about being an irresponsible idiot and misusing licenced drugs.

9 out of 37 million....

But American doctors, who tracked more than 37million people, said the injections put users at higher risk of nonarteritic ischemic anterior optic neuropathy (NAION).

However, overall risk of developing the condition while on the jabs remained 'low', experts said.

The medics cautioned that further research was still vital to further prove the link and said they couldn't be sure why the medicines, collectively known as GLP-1 agonists, may trigger the condition.

It comes as separate research released last month detailed nine cases of US patients who went blind after taking semaglutide or tirzepatide, the active ingredient behind Mounjaro, another popular weight-loss jab.

So @nameey did you even read the article? I'm guessing not and you just wanted to stir anti weight loss jabs eh?

It's been really good for me.

Well there are plenty of people abusing the drug (lots of posts all over the internet with people making up their own rules and doses instead of taking it as prescribed) but it’s also going to cut obesity rates massively and improve a lot of people’s health

I think there will be issues but due to the drugs being misused eg:

• people lying about weight to get it prescribed for longer
• people extracting the 'golden dose' and doing this incorrectly, not administering properly or other associated issues eg hygiene, injecting too deeply (not possible with the proper pen injection)
• side effects causes by people eating crap and potentially causing greater issues
• buying dodgy semaglutide etc from non registered prescribers

All the above I have come across in online forums

I think if it is followed correctly the negative effects will be minimal

I do think there are long term implications with WLI that we aren’t quite addressing properly BUT the problems aren’t the drug - it’s people who are using the drug when they shouldn’t be.

I worry about the effects too. I have a niece in law/ step son and daughter in law all taking it and they are young with very young children. They were “heavy” but not obese but I can see how much better than feel being thinner. I have seen phen phen then alle’ in my lifetime and phen phen in particular caused serious cardiac issues. We won’t know until there are longevity studies completed. I worry most about gastroparesis which is very very difficult to cure. I would like to see It be successful. I have young obese patients and I can see all their future health and emotional problems already starting. Weight loss is life changing but science has yet to prove a safe way to do it and maintain it but it’s possible ozempic is it.

That's a lot of assumptions.

The link about people going BLIND.... it's a possible small increase in the risk of an extremely rare eye condition, which is actually caused by a sudden drop in blood sugar not by the medication itself. So a possible risk to the people who are susceptible to it of any kind of calorie restricted diet, or short term period of not eating.

I guess having been on Mounjaro for 7 months that if I was going to go BLIND it might have happened by now!

Pass the bingo card please.

Shame a pp used a daily fail link, but the blindness thing is the reason I wouldn't use it. (There's been a lot written about it).

Every medication I've ever had, I've always got at least one supposedly rare side effect. So I just couldn't risk it personally. I'm sure millions of people can use it and be fine but I wouldn't feel confident, knowing how I am.

I think the opposite OP. The anti- inflammatory effect may well mean a lot more of us take these drugs in the future, not to deal with obesity:-

https://www.theguardian.com/society/2025/jan/20/weight-loss-jabs-linked-to-reduced-risk-of-42-conditions-including-dementia

I do feel there can be a rush to lose weight very quickly on weight loss injections which does worry me. I’m on Mounjaro and aiming for 1-2lb a week.

I thought the drugs affected hunger? So you’re eating less. It’s hard to get enough protein when you’re eating 3 meals but when you’re eating far less than that I can imagine it would be tricky.

Exactly what I wanted to say.

I’ve been prescribed Mounjaro through my GP because I fit criteria and am being properly monitored.. When I was telling my boss; she was horrified and went straight to ‘why don’t you come to slimming world with us’ and went off to reel a lot of negative stories (which usually come from people who have misused it) She then went on to tell me I will just pile it all back on once I finish.. (doesn’t that happen with all diets?).

I have noticed that people delight in telling you the bad side of it but not the positive.

Don’t get me wrong, I know there can be side effects and some people will suffer negative reactions but that risk comes with all prescription medication.

she also called it a ‘quick fix’ which it isn’t. I will be on it for a while and have completely overhauled my eating habits because I want to do it right and continue a healthy lifestyle once it is done. It’s not all just eat what you want and jab yourself at all. It’s a complete lifestyle change - if you are going to do it properly.

Congratulations, that’s a really huge health gain.

I'm kind of okay with people who lie to get drugs having a bad time because of it. Being responsible for your actions used to be a thing

Reading the Daily Mail can lead to blindness.

Or complete and utter stupidity…