to think more negative effects will come out from Ozempic use?

One of my friends is a lifelong endocrinologist and internationally known obesity/diabetes researcher. He says that these drugs are very safe and have been in use for a long time. Decades.

My sister has stage 4 cancer and her oncologist, also an esteemed physician researcher, has no problem with her patients taking Ozempic. The benefits of lower weight to cancer patients are well known.

What?

I am currently on Rybelsus (oral Ozempic) for diabetes, not weight loss. It was originally prescribed to regulate blood sugar in diabetics. I am not overweight. However, getting from "normal" to "thin but not too thin" could definitely help me to possibly be able to get my blood sugar back into normal range and go off all drugs. So I am hoping to only be on these meds for a couple more months, six months total.

That said, yes I do wonder what might come out about Ozempic and the other semaglutide drugs in the future, especially when they're used long term. (For diabetes, I believe the usual expectation is to be on them forever, though I don't plan to do that myself. If the weight loss isn't enough to correct my blood sugar, then I will switch to one of the old tried-and-true meds diabetes meds).

Now they're saying Ozempic also greatly helps with alcoholism. It really does seem to be touted as a "wonder drug." However, as far as I know, the long term effects simply are not yet known.

If we're talking about a sample size of one, here is the difference WLIs have made to my bone density (and muscle mass) since I started them.

I'm always very open to hearing about the negatives as I want to make sure I'm fully informed about the potential side effects of any meds I take. YOU'RE ALL GOING TO GET OSTEOPOROSIS, FATTIES isn't anything to do with helpful discussion about WLI though.
As others have informed the OP, Avery had an eating disorder and didn't get it through a reputable medical supplier. That has as much to do with those of us taking it as it should be used as Matthew Perry's painkiller addiction does any of us using ibuprofen.
I would love if the two conversations could be kept completely separate in the press in future. If there is an increase in deaths or serious side effects from people taking it as prescribed then fuck yeah I want to hear about that. But people abusing it like Avery did has absolutely nothing to do with that.

People talking about online pharmacies requiring videos of you stepping on scales etc...

All this sort of thing is easy to fake. Unless you are naked you can hide weights in clothing, or send a video of a friend, or tamper with your scales. Thus why plenty of people are accessing it who are neither diabetic nor obese.

It should be illegal to prescribe it unless you are seen face to face & your weight/bmi checked in person, including for follow ups. The research is not there to demonstrate that the pros outweigh the potential side effects unless you are actually obese.

To be fair thst sounds like they were doing it to have fun and staying thin was a side effect...

Seems unlikely. GLP1 RA have been used as a treatment for type 2 diabetes for 20 years with few issues.
It's idiots using it off license that are going to come to harm

“Someone told me ages ago”

you need to quantify ‘ages ago’ and the medical credentials of said person before you type such things, anyone can say anything given your rather loose criteria.

I think the singer in question has had an eating disorder for years - she would have got osteoporosis from that. I won’t read it as it’s the daily mail and they had another story recently that turned out to be shite as well.

@BeardofHagrid
Do you feel that way about all medications? Or are you lucky enough to be so healthy you're not faced with the dilemma of having to weigh up the benefits and potential costs of a prescribed medication? (btw, do you have to pay for your own life-saving medication yourself because the NHS won't?)
Is this 'someone' involved in medical research? I hope they share their findings as there's an awful lot of T2D, who've been taking glps for years, who'd like to hear what they've discovered.

Oh brilliant

reaches for more chocolate

I got it from a private pharmacy in the UK for weight loss. I’m not diabetic.

There is a thread like this every few days, where is the poster with the bingo card.

I reckon it’s a small handful of obsessives name changing and repeatedly doing it as they can’t get the drugs or resent them.

Someone once told me that's just fine, so don't worry about it @soupyspoon!

I’m staying on mounjaro for ever, a low dose, I feel awesome, all health markers improved, off my bp meds, a healthy weight again, blood sugars controlled, insulin well managed. I also eat my protein and work out, cardio/strengrh at least 5 days a week.

id not take much store by someone with an eating disorder who developed osteoporosis, it is the risk she sadly ran with her eating disorder.

but no one has to take it. You don’t need to op. Curious. Do you worry about other meds? Or just weight loss 😂

Oh well if someone told you...

GLP-1 medication doesn't 'seriously mess with your anatomy'. It is also hardly your business to decide what's 'worth it' to other people who aren't you!

You're right, what are the epidemics likely to be caused by layering flab upon chub upon flab upon chub. Particularly around the midsection? Is there any information about the health issues caused by that?

I think one very big issue is that people use it to loose weight as fast as possible. Like the 3stones in 3 months mentioned on this thread.

At that pace, regardless of how you loose weight, you’re going to loose muscle.
Much better to loose weight slowly (1~2 lb a week, as advised for other diets). But people are approaching that as they do dieting - quick and strong wins are always seen as the best. It’s very visible on the MJ threads on MN.

So basically, it’s not the medication that is an issue. It’s the way people approach weight loss as a whole.

And yes resistance training would help too. As would changing the way you eat (aka full lifestyle change) rather than just looking at scales.

🤦🏻‍♀️ Messing with your anatomy? Do you perhaps mean physiology? By that measure all drugs would be avoided.

"Someone one told me ages ago..." is quite the source for medical information.

And?

I can only just about read it due to ad blocker but this is a right pile of shit

Shes only been on it a year, how much weight did she lose?

Weight loss in one year (even if its a huge 12 stone or something) isnt going to give someone osteoporosis, its something that develops over many years

It has been used for years by diabetics ' are we seeing huge issues with that population?

There areplenty of endocrinologists and other doctors who accept that it will be a long-term, potentially life-long medication for some. As blood pressure medication or statins are.

What is your experience of this drug class, OP?

After all there are no risks at all associated with obesity are there? Stay fat fatties - know your place!