to think more negative effects will come out from Ozempic use?

OK sorry I didn't read It properly but the rest of it stands.

Unlike previous drugs GLP1 has a very safe profile with 30 years of human data.

They are also very effective. I mean a 2inute Google says the first one you mentioned was pulled due to ineffectiveness alongside an increase in risks.

The risks of this class of drugs are minimal and the drug is very effective at reducing obesity.

Those drugs are all amphetamine based

That is not accurate.

Those drugs are all amphetamine based, a class of drugs with significantly worse side effects then GLP1s

One of the safest things you can do in drug development is repurpose an existing drug as you have in this case 3 decades of human data on the drug. Long term use has been shown to have far more benefits then negative effects.

https://www.bbc.co.uk/news/articles/c9d5pq4y5wpo

The use of these drugs are also so safe their use is being expanded having just been approved to adress chronic kidney disease in diabetic patients and clinical trials for a variety of things including neurodegeneratove disease like alzhimers disease and parkinsons where other effective treatments are massively lacking.

Unlike amphetamines which due to side effects have very very limited uses.

I think there’s quite a big difference in being informed between getting properly prescribed medication that you genuinely fit the criteria for, reading the info leaflet, taking the meds the right way, and being aware of developing scientific thought, and reading endless threads with Daily Mail links to stories with bad stats, inaccurate information, and zero research, and posters who were told by their sister in law’s friend who’s a dental nurse, and ‘someone told me once they kill you’ contributions.

Can somebody start a "concerned" thread for me and others who were prescribed Methotrexate ........ a drug so toxic that you have to have your blood monitored every month. Adverse reactions include ulcerative stomatitis, leukopenia, nausea, and abdominal distress. In addition, infections, malaise, fatigue, chills, fever, Thromboembolic events (including arterial thrombosis, cerebral thrombosis, deep vein thrombosis, retinal vein thrombosis, thrombophlebitis, and pulmonary embolus), pericarditis, pericardial effusion, hypotension, sudden deathToxic epidermal necrolysis, Stevens-Johnson syndrome, exfoliative dermatitis, skin necrosis, and erythema multiforme, erythematous rashes, pruritus, alopecia, skin ulceration, accelerated nodulosis, urticaria, pigmentary changes, ecchymosis, telangiectasia, photosensitivity, acne, furunculosis. Potentially life-threatening hepatotoxicity, pulmonary damage, and myelosuppression.

And that's just the first half page of about 20 pages.
A very toxic drug that's not even the best treatment but it's the go to as its cheap.
Did I mention the birth defects and carcinogenic properties?
Weight loss injections aren't even in the same league.

I want a concern filled thread from all the drug side effect concerned folk because I know they will know all about it because they will be just be as well read on all drugs as they are on Ozempic🙄. I simply can't understand why I haven't seen 200 “Deeply concerned about Methotrexate" threads. Can't figure it out at all........ 🤔

Can you name a single medication that doesn’t have any side effects?

Honestly, anyone would think this is the first medication to emerge with links to possible side effects. Apparently someone on this thread went to the States and saw an advert for wegovy that listed numerous side effects. But they didn’t see adverts for any number of medicines with a long list of side effects recited at the end of each and every one of them. Just wegovy?

Medicines have side effects. All of them. The user must weigh up whether the potential side effects are worth it for the benefits of the drug. Which is what lots of people are currently doing with WLI. And with 30000 people in the UK dying each year, from obesity related diseases, I’d say it’s a punt worth taking.

I don't think it would be surprising if more effects came out. I think any kind of drug that has such a wide system effect has a high chance of having some unexpected side effects that will emerge as they are used by more people for longer periods of time.

Look at Depo-Provera, for example, many people were assured it was very safe, I know people that have been taking it for 20 years. Now there are two class action lawsuits, one around brain tumors.

Of course with someone very obese, or diabetic, the risks of that might well justify those unknowns, but I think it's important not to fool ourselves that serious side effects could well emerge.

Except...... that's not what it does.

Perhaps if all those "concerned" people were less offensive......

They are lovely aren't they? Such genuine concerned people. 🙄When do they ever sleep what with worrying day and night about side effects in every person on earth taking every drug ever marketed......... oh wait........ They arent.

and I bet you can't weight......

Yes but paracetamol risks don't give bitchy women the excuse to criticise fat people in the guise of faux "concern"

Because like a lot of unpleasant women, she can't bear the thought of fat people losing weight because she won't have anybody to look down on in her pathetic bitchy life.

Absolutely this. It's the most bizarre, petty bitchy thing I have ever seen.
Of course dressed up as "concern". Because of course they get "concerned" for users of every drug on ye market. 🙄. Not.

And you will be first in the queue rubbing your hands together saying "Bad fatties, it what you deserve"

I would suggest she got osteoporosis from her eating disorder long before Ozempic. But hey, if it makes you happy.....

Time will tell, I'm sure. It's distasteful how people seem to almost be keen for dire side effects to be inflicted on people taking Wegovy or Mounjaro for obesity. Hence seizing on these stories of foolhardy people experiencing issues after making stupid choices, and suggesting it's an issue for people who are taking the medication because it was appropriately prescribed to them.

What was absolutely certain for me was dire health outcomes from remaining morbidly obese. So as with many decisions, it's a balance or risk versus benefit and it's clear what the outcome of that balance is for me.

I was thinking of Fen-Phen, as mentioned by a pp.

Fenfluramine/phentermine - Wikipedia

(There's also Lorcaserin, Rimonabant, Dexfenfluramine,and others, as well as good old amphetamines and methamphetamine products.)

Spot on. Dressed up as “concern”.

What are these amazing, life changing weight loss medications that have been on the market and then quietly withdrawn after killing a few people? I’m in my mid 40s and can’t think of anything…

Meh, given I’m in my 50s and morbidly obese I’ll take my chances with the risk of the jabs compared to the risk of remaining this fat

I love to be well-informed of emerging risks and potential downsides. This story in the news is not an emerging risk or a potential downside. It's a story about a woman who has made many very poor life choices having a consequence that she's upset about after the latest poor choice went badly. It's not new information from the drug manufacturer, or from new drug trials, or from the MHRA, or from another source that might be an authority on this particular medication.

She will have osteoporosis from her eating disorder not from her medication. It is a very very common side-effect of anorexia and bulimia.

They are only defensive and aggressive in the face of ignorance or deliberate goading,

these threads have brought out the worst in some people. Peiple like the op with their fake concern. They never want to reveal their real issue,,jealousy, resentment, instead proclaim their altruism , look at the op, who apparently spends much of her time concerned about other random prescription meds that she doesn’t take .

yet posted something idiotic about a woman who has an eating disorder and got osteoporosis, simply as she was taking th4 drug when she shouldn’t, she almost salivated trying to blame the drug,

thr issue isn’t the drug, it isn’t posters responding, it is the small minority of people consumed with jealousy or resentment about the drugs,

People do get incredibly aggressive and defensive on these threads. I would think they would like to be well-informed of emerging risks and potential downsides - especially as they claim to be well-informed already.

I probably qualify to take a GLP-1 agonist of one name or another, but having suffered gastritis with really painful and distressing symptoms the last few years, I would not want to take the risk of causing problems with my digestive tract, as reported by some users. And some of those problems are serious and apparently irreversible.

Also, I am old enough to have seen a few other amazing life-changing weight-loss medications come on the market, eventually kill a few people, and be quietly withdrawn from sale or just massively lose popularity due to unpleasant side effects like soiling yourself. Time will tell, I suppose.