to think more negative effects will come out from Ozempic use?

I had some pretty spectacular suppression on the early doses of mounjaro. I don’t get that now on a higher dose. I had my lunch an hour and half ago and am now feeling a slightly rumbly stomach. I’ll not eat now until dinner.
Being hungry has never really been an issue for for me - I’ve quite happily only eaten 2 meals a day for most of my adult life and not snacked in between. My problem has always been eating meals that are far too big and far too caloric. What the medication has done for me is allow me time to get to grips with what I should be eating, portion wise, and understand how many calories I should be eating to be in a deficit.

Mounjaro doesn't remove hunger. It does in a small number of people but that's not how it's supposed to work. It reduces hunger so it's manageable. I get hungry at mealtimes, I just don't get chew my own arm off hungry, or hungry when I've just eaten an hour ago, or still hungry even after eating a meal hungry. If you've not experienced what it feels like to have a large appetite driven by hormonal issues then you really can't comprehend why it's so difficult to just ignore being hungry. I don't want any drug to remove hunger from me! But to feel a normal slim person's level of hunger is fucking revelatory I can assure you. I'm not a weak person, I am a person who has an abnormal hunger level when I'm not on this medication.

I don't feel full all the time on Mounjaro. I just don't feel extremely hungry and I can take or leave snacks, so I choose to leave them. I still eat three meals a day, although smaller portions than before. Which makes sense because I'm trying to be in a constant calorie deficit.

I dont know if that's what you're after @JacquesHarlow but that's my personal experience.

I think what you're saying is that GLP-1 medications are unhelpful because they totally remove any feelings of hunger. I don't think that's true for the majority of people on them. I think it reduces the feelings of hunger or the mental obsession about food to a manageable level. Not to nothing.

Also, I was morbidly obese before I started. Now I'm not and I'm approaching a BMI of under 30. That's better for my health and long term wellbeing, even if it's morally or psychologically wrong to suppress hunger to some degree.

I'm going to be absolutely nailed to the wall for this but I don't care -

Am I allowed to talk about hunger on this thread?

You know. The H word that is never, ever spoken about in an objective way when we talk about dieting.

The reason I am mentioning it is because I think (and yeah it's just my opinion) that a lot of people in the Global North have completely forgotten what hunger is, and why it is a necessary part of our day.

We snack constantly. We say we "need wine" at the end of our days. We 'reward' ourselves with 'treats'.

It all leads to a world where a vast majority of people act on hunger instantly rather than allow themselves to be hungry for an hour or two before a mealtime.

For me there's so much psychology in this.

Am I allowed to actually talk about this?

Because Mountjaro for example has the effect of suppressing hunger by "making you feel fuller for longer".

Which is fascinating to me, because I don't actually understand or endorse that whole concept.

The whole idea of "I must feel full at all times" just makes my head spin...

Is anyone going to ever talk about this honestly on Mumsnet, or will it just be shouting folk down about thin privilege or whatever I get lobbed at me usually?

Oops @lettyraines has had her comment to me deleted. Just to say, I didn't report it 😅

@lettyraines 😅 That comment's 'spiteful'? Jeez
I'll try to explain but know I'm probably wasting my time. One of the problems with SM is that very few, if any, people with a different perspective ever changes their position, or allows themselves to learn anything new, or hears a story which shifts their viewpoint an iota....or admits that anyway. My point, which I'm sure you understood very well but choose to respond to in a weird, wounded way ironically, is basically that this thread is, as usual with this particular subject, a waste of time as the people who say they're looking for a polite discussion don't actually engage when someone from the opposing viewpoint tries to explain something - in this case why people get upset or cross or impatient or whatever (in a perfectly polite way too, not the first time on this thread either). They'd much prefer to trade insults and act the victim, bleating about how we're all so mean for daring to challenge what they say. That's fine if it's how they choose to pass their time and no doubt, they're getting plenty from the affirmation. It's just interesting when it's as obvious as it was in this instance. You're welcome.

Just to put forth another side that is often overlooked in these conversations. HCP view of weight and obesity is as skewed as the general populations. So alot of doctors view it as a failing of the individual and are as such uninclied to help outside of advising to move more and eat less. A mantra that has been entirely disproven to be sufficient to overcome obesity once an individual is obese ( it is something that makes you less likely to ever become obese). This is even more prevent towards females. Below is an exert from a paper

https://pmc.ncbi.nlm.nih.gov/articles/PMC4714720/#:~:text=Weight%20Bias%20in%20Clinical%20Care,-Unfortunately%2C%20negative%20societal&text=A%20recent%20study%20of%202%2C284,in%20their%20lives%20(21).

"The importance of addressing weight bias in clinical care is further highlighted by evidence that weight bias by HCPs can impair quality of health care for patients. Evidence suggests that HCPs spend less time in appointments (45), provide less education about health (46), and are more reluctant to perform certain screenings with patients who have obesity compared to thinner patients (47). Furthermore, some physicians view patients with obesity as less adherent to medications (28), express less desire to help these patients, and report that treating obesity is “more annoying” and a greater waste of their time compared to providing care to their thinner patients (45). In addition, perceived weight bias in the health care setting contributes to reduced health care utilization among patients with obesity, especially for women (35,48,49)."

This scares me more then potential side effects

People can access additional support if they want via online pharmacies that offer a more frequent and personalised level of contact. I think requiring it to be a private doctor is unnecessary and not justified by the rate of serious side effects that currently occur. That's also the position of the MHRA.

It's not "rolling the dice" as if its some kind of unknown and untested drug. People are taking it according to the required guidance. They are told about the possible risks and the symptoms of serious side effects that shouldn't be ignored. Why is taking a prescription medication that has been correctly prescribed to you, according to the instructions "rolling the dice"?

Many GP’s won’t have anything to do with a privately prescribed medication and won’t supply any level of monitoring or support.

I said in consultation with their doctor - which then would imply a level of monitoring as treatment progressed. By all means, just roll the dice.

How would those side effects have been prevented by having seen a doctor before being prescribed?

Well, because having read reports from people on the frontline seeing patients with serious adverse effects, often the signs of something really ominous but treatable are put down to just another symptom to suck up while on the treatment. Whether that's bowel obstruction leading to bowel perforation, or gallbladder problems then requiring removal, or gastroparesis.

Why in consultation with "their doctor"? I don't have a personal doctor. My GP hasn't seen me in person for several years and doesn't even want to see me in person or speak to me for my high BP medication review. That's done via me doing home BP checks and a phone call with a pharmacist.

The online pharmacy is very capable of taking my medical history, informing me of the possible side effects, and then reviewing my details before deciding whether to prescribe a WLI to me or not.

Are you saying your BMI is low 30s? Sorry, the thread has been going on for a while, not sure if you've said this before. Obviously you don't have to disclose that but it just sounded like that's what you meant as it was in response my question.

Yes, it was very concerning that 'the pharmacist' on this thread clearly didn't trust conventional medical trials and would only accept drugs were safe to use over twenty years after they appear on the market? Does she know something we don't?

@Caffeineneedednow
Interesting to see who hasn't responded to it, isn't it?

I personally would not be taking it.

Other people have to make their own decisions, don't they, hopefully in consultation with their doctor.

I was interested in what you mean by seriously obese too. Do you think people with BMIs in the low 30s shouldn't be taking it?

Namaste to you, too.

Well you can thank your fiend twiglets for the repeated going on about friendly debate. No idea why.

I had a go at you and used that as a way to wind you up as your initially sarcastic response to me was clearly an attempt to wind me up. Karmas a bitch.

I'm quite happy to have a discussion but I am a trained scientist so my idea of discussion and debate requires factual evidence which I have provided throughout.

You say you are not trying to stop people taking the drug but you just want to highlight the danger / discuss. Do you not see the paradox? If I told my sons it was dangerous to play on the road. I wouldn't follow that statement up with but crack on.

If my friend decided now was a great time to go on holidays to the Ukraine. I would very much highlight why that is a dangerous plan to try and stop them. By virtue of highlighting a danger in a disproportionate manner as this thread is doing then you are trying to stop people taking the drug, weather your actively aware of that or not it is how it comes across.

Maybe address your thin-lipped questions to someone else. I really have no desire to engage with you,

Nailed it, couldn't agree more.

Define seriously obese?

It was suggested up thread these drugs should be used obly in morbidly obese individuals. Is this what you mean by seriously obese?

Is there a reason your assement disagrees with the MRHA?

Well, of course there aren't lots of "ongoing debate threads" there. But there are plenty of opportunities to discuss WLI there, with people who are supportive of WLI because they are on WLI - just as you'd expect.

I don't know why the idea of a "debate" keeps coming up. I have been lectured multiple times and given condescending advice about my "debating" skills, or lack thereof, on this thread. Nowhere else on AIBU or Chat is one required to post as if they are in some sort of disorganised debate. It's just bizarre.