to think more negative effects will come out from Ozempic use?

Offensive does not necessarily mean writing abusive things.
It means that people are constantly "going on the offensive" with constant anti GLP comments based on their own assumptions and bias. Which in return makes people who use the drug legitimately and safely and with great health benefitd become very defensive. Words have different meanings and context.

We welcome anything negative, but it needs to be factual not nonsense. People will challenge bullshit.

Um I was responding to you. Unless you’re Justine, then I’m fairly sure it was obvious I wasn’t saying mnhq had a low bar. I said you did,😂

and I’m afraid I’m sorry to disappoint again, I’m not unhappy. I’m actually delighted, I cannot believe they cured obesity and I feel so lucky I’ve been able to access the medication and it has worked so well for me. I love being a healthy weight, having loads of energy, that my health markers are improved. And I love i have refound my vanity and able to wear some gorgeous clothes.

the unhappy one is clearly you, who is driven to start daft threads, and then posting sullen and rather batshit responses.

and yes, taking the drugs do make me happy, or the effects of them make me happy . I will continue to take them to maintain. I feel so lucky to be able to do so. I fully intend to continue to be a slim and healthy weight and not have to worry about deprivation or managing the scales again.

but you can crack on with your concern and mad threads. Although it doesn’t seem to be making you happy. Poor you.

@janeavrilavril if people put forward negative things that are untrue and without evidence then of course people will challenge those statements. The kind of negative nonsense that's all over this thread gets repeated each time one of these "concerned" posters starts a thread about it. Usually after another sensationalist Mail article.

I mean, that's not even slightly evidenced by this thread. It's something you've made up and decided to believe.

It is like a cult, it is apparent in many responses here. Nothing slightly negative can be put forward.

I just thought people worried with drug side effects might like to. Because you know...... "concerned".

Oh...... you mean it's just Ozempic that worries you to this extent. Riiight.

Please link the class action suits.

Ad a pp said I belive these are some who failed to be aware of the known side effects of the drug. This information is in the information leaflet and as others have said listing these is a legal requirement of advertising the drug in the US.

Yes this drug has side effects no one is disputing that. Most are mild and temporary ( usually gi related). Perhaps minimal was the wrong word but the side effect profilenjs no more dangerous then that of say the combined pill. However in the many years I have been on mumsnet I have never seen a thread about the potential dangers in the way the conversations regarding glp1 agonists are.

Hers is a the risks associated with the pill

https://www.drugs.com/article/birthcontrolpill-risks-benefits.html#:~:text=Combination%20pills%20that%20contain%20both,estrogen%20due%20to%20medical%20reasons.

To be clear I am not saying people shouldt take the pill but rather all drugs carry risk. However a drug that has been in the population for 30 years gives us a good data set of side effects. Which for this drug are small compared to the well established risks of obesity.

The specific concern of the OP regarding 1. The osteoporosis and 2. The blindness study have been discussed. No one is ignoring them they are saying 1 was due to a separate disease and 2 is so exceedingly rare that the risks are minimal.

On the blindness I would add that 8 / 9 affected suffered from diabetes which the study acknowledges was a contributing factor.

@Twiglets1 that's my point, plenty of lawsuits but no class action lawsuits.

But as others have pointed out, the litigation landscape in the US is very different. And the FDA is often not fit for purpose.

If Doritos were required to carry the same level of health warnings on them as drugs were there would be class actions against them too.

But the numbers of people losing 'huge amounts weekly' are very small. The drug isn't designed to make people lose huge amounts quickly. That's not how it works or how it affects most people. Most people lose 1-2 lbs a week on average. Some people are very sensitive to the drug and lose more at least at the start but as they develop a tolerance to it the rate of loss decreases. WLI are nothing like VLCD.

From my experience and what I see every day on the weightloss threads, most people are losing upto 2 lbs a week, often small gains, staying the same or closer to 1lb a week.

The difference the WLIs make is that it becomes sustainable, so rather than sticking to the diet for a month and then slipping, it is possible to continue for 6 months or a year or 2 years and remain consistent throughout.

Sure, everyone knows that, that’s irrelevant of drugs. Looking at the monthly threads, most folks lose up to a couple of pounds a week, some less, some more, average is healthy. So that’s good right.

Nope. Anyone who takes part in rapid weight-loss, who does or doesn't need it, there will be side effects. You can't loose huge amounts weekly, and not be causing some long term issues. I'm not against it, but if not done sensibly, there will be side effects. Same if you used shakes, or any VLCD programme.

You can take out a law suit about anything to anyone in the US and it will drag along, it doesnt mean it has any validity.

Wow. I’m surprised. Again. Just how many people are so jealous and resentful over these drugs. it’s a small number but bloody heck, the obsession, I feel pity.

The lawsuit comment actually made me laugh out loud, it was similar in vein to the op blaming the drug in the op and shows a lack of knowledge, or a desire to use anything,

the bottom like is all drugs have risks. 2000 people a year die from nurofen. There is no prescription med without a warning on the label.

the risks of obesity are signficant. Very signficant.

in the USA nearly 17 milllion on the drugs, less than 300 deaths, not one proven to due to correct usage of a legitimate drug. The stats speak for themselves.

the thing I don’t get is, how can you be so obsessive and consumed by something that doesn’t impact you that you start posting shite all over the internet. In some odd futile attempt to get people to stay fat and struggle

you can’t get them, tough shit. You want to have slim privalge, tough shit. It’s gone. You want others to work as hard as you to stay slim. Tough shit.

the horse bolted.

I just googled law suits against Ozempic & Wegovy in America and there are some law suits … not sure about class action law suits as was just a 5 minute search.

Most of the cases seem to focus on the manufacturers not giving enough warning of the possible side effects. Which I think is nonsense really as in the UK at least the potential side effects are clearly listed in the leaflet that comes with the drug. I suppose the issue is not everyone reads the information properly which personally I feel is their responsibility & not the fault of the manufacturer.

@lettyraines can you link to the class action lawsuits against MJ? This link suggests there aren't any. www.drugwatch.com/legal/mounjaro-lawsuit/

I agree that these drugs have been around for a long time, so the risks and side effects are very well known. What's changed recently is their use solely for weight loss, and the instances of inappropriate prescribing.

People have misused/abused drugs since the beginning of time, which means there has to be education and controls.

Personally I think that they are an absolute game changer, with even more potential to combat some of the lifestyle diseases our modern world has inflicted on us.

What would be even better is if we banned UPFs from the planet, reducing the problems that these drugs are needed for in the first place.

I'm not going to argue the toss, point by point, however, just from the wiki entry I linked:

"Fenfluramine was marketed by American Home Products (later known as Wyeth) as Pondimin, but was shown to cause potentially fatal pulmonary hypertension and heart valve problems, which eventually led to its withdrawal in 1997 and legal damages of over $13 billion."

Fenluramine had a weaker effect on its own. It was available from the 1970s to late 90s. Fen-Phen was a combo drug that was considered a wonder drug for weightloss in the nineties, until the reports of heart problems started flowing in, and a number of deaths from heart problems in users occurred. It was also viewed as useful for drug addiction... Wyeth set aside $21.1 billion (U.S.) to cover the cost of the lawsuits.

Given there are already class action lawsuits in the States, involving Ozempic, Rybelsus, Wegovy, Trulicity, and Mounjaro, from people claiming they weren't properly informed of the risks, I really don't think you can say "the risks of this class of drugs are minimal".

I’ve just had some post menopausal bleeding and referred on the cancer pathway. My recent weight loss, using Mounjaro, significantly reduces my breast, uterine and ovarian cancer risk. It’s also lowered my blood pressure meaning, I’m now at less risk of stroke, heart disease and kidney failure.

https://pmc.ncbi.nlm.nih.gov/articles/PMC8878541/
The effect of GLP 1 agonists on osteoporosis appears to be neither protective nor a risk of these drugs ie it has no effect.

This is based on a systematic review of the existing literature not a single case of an individual who missed the drug and developed it most likely die to her eating disorder.