DH and me on Mounjaro weightloss injections

I'm not making claims. I'm stating facts.

People with insulin resistance can't process insulin properly. This can lead to weight gain, and causes cravings for carbs and sugars.

People who gain weight can become insulin resistant and that's how you get prediabetics and diabetes type 2.

It doesn't matter how they became obese whether that's through primarily overeating or secondary to a condition or medication. They're not exempt from developing insulin resistance.

Once you are insulin resistant then you can't really reverse that without intervention.

It's not my job to educate you. You've clearly got an agenda against people trying to use modern medicine to benefit their health with a faux concern for side effects.

Google scholarly articles are free. You can browse them at your own leisure. Or you can continue arguing with people on mumsnet.

You have a difference of opinion, that’s all. Your lack of community outside of your relationship to share your experiences is your responsibilityn not his. You need to respect his decision/ opinion just as much you expect him to respect yours.

Yes, I am aware of that. My comment was sarcastic - hence the mentioning of laudanum. I see that wasn't picked up.

I suppose neither of us can truly say how low risk or safe these drugs are. However, I still cannot see how they can solve the core issue. I suppose we'll just have to see how people get on when their year is up.

@GiddyRobin also, if choosing examples of medications declared to be safe enough for prescription, best to choose examples from modern medicine that complied with the same standard of testing that drugs now on the market have.

Nothing is "safe". But they are low risk, and the risks of side effects or adverse reactions is significantly outweighed by their therapeutic use. Hence being approved in the UK for weight loss.

Yes I can see that. But it doesn't prove that food noise is a purely physical issue. The reduction of appetite is one thing; food noise is another. Not only obese people suffer with food noise.

I was giving you my personal experience. The medications of course have been extensively tested and have been shown to reduce appetite, create feelings of fullness for longer and feeling fuller sooner. So there's that.

My point is that lots of things have been claimed to be safe. It doesn't mean that they are just because you want them to be.

Ah, okay. So your claim that this is a completely physical response is only through your experience of injecting yourself with said drugs, not through any rigorous scientific research? Cool.

@GiddyRobin "diet pills" presumably you mean things that were basically speed? Do you think they went through the same testing process that modern medicines go through? As for laudanum, you're being absurd to compare a Victorian era drug to modern medicines and I'm surprised you can't see that.

It's clearly a physical response because immediately on taking the medication, my response to food changed. Why do you think it's not to do with the medication?

Of course I am, but you're the one making claims so I'd love to be provided with reputable sources!

Well surely you're capable of using Google?

You can do your own research on insulin resistance and the hormones responsible for hunger. You should probably start with Ghrelin.

So are you saying that every obese person taking this drug, who suffers from food noise, is struggling with insulin resistance? Please provide evidence that all food noise is caused by this.

I'm more than happy to read up on this.

I can see you're talking about food noise but you're talking about something you actually don't know anything about and it's showing.

Food noise, the constant thinking about food, the cravings and how it drives you isn't a psychological issue. It's very much physiological and driven by hormones in our body. Those of us with insulin resistance which can be a cause of obesity and caused by obesity have an increase in hormones that drive hunger and fuel cravings for specific things usually sugar and carbs.

That's food noise. It's not a lack of willpower. It's not something you can CBT or DBT your way out of. Therapy can help you identify why you're eating the things you eat like it you're dopamine searching so you can make other choices but not every one is eating to fill an emotional gap.

Medical conditions and medication can also cause food noise because they interact with our physiology.

How do you know the health risks are minimal? Can the studies now see far into the future? Diet pills were also marketed as being safe. So was laudanum.

How is it clearly a physical response? Happy to read any studies that prove this is the case. The only physical response that I'm aware of is how stretched the stomach is or isn't from eating too much/too little.

The cycle you describe is mental. Stages of restriction and stages of overeating.

@GiddyRobin the health risks are minimal and counterbalanced by the very real and ongoing risks of being long term obese. The injections do work, they produce weight loss. Maintaining after weight loss is an issue for all weight loss methods.

It seems like a waste of money to you and that's ok.

The injections are probably cheaper than private therapy!

@GiddyRobin what you seem to be absolutely missing is the fact that "food noise" is clearly a physical response. It is altered by the injections because it's altering your body chemistry. Did you miss the part where I explained how I have been overweight, obese, from childhood and been on a constant diet/gain cycle since then? That has had an effect on my ability to maintain a calorie deficit or even a calorie neutral diet. It's not something that therapy can tackle, it hasn't been something that therapy can tackle.

It isn't wrong, you're the one making this all about moral judgments. It just seems like a waste of money, a risk of health, all topped with a high likelihood that it won't work.

Dealing with food noise while there is no food noise isn't going to combat it long term. As soon as those thoughts begin again, it'll be far harder to stick to it.

So using meds to cut out food noise to allow yourself to work on your relationship with food in preparation to come off the meds is wrong?

I am talking specifically about food noise. Those with medical conditions are a separate issue, though it's still entirely possible to lose weight without drugs.

Obesity doesn't just happen. Just as drastic weight loss doesn't just happen.

This thread is bizarre in places.

I'm talking specifically about food noise. Not insulin resistance. Please read what's actually being written.

That's silly.

Lots of us are doing some sort of therapy or have access to supplementary resources that help us reshape the way we think and interact with food.

Some of us have done therapy for overeating and without the medical intervention it has been unsuccessful.

And we do know the long term effects of obesity which include but aren't limited to: hypertension, high cholesterol, diabetes, organ failure, cancer, stroke, heart attacks and death.

Mind boggling that you think the route to treatment for obesity should be the same as restrictive eating disorders when they're two completely separate entities. If there was a medication that could be used to effectively reverse organ damage and increase the appetite of people with restrictive eating disorders that would be absolutely miraculous but at it's core restrictive eating disorders are usually stemmed from trauma with a need for control and a personal desire to improve is needed to recover from eating disorders with a massive failing mental health system behind it, a lack of inpatient beds within rehabilitation centres and sadly a large portion of people with restrictive eating disorders die. There's a huge comorbidity association between autism and conditions like anorexia and bulimia too and it requires a specialist and tailored approach.

Being obese and a disordered restrictive eater are not comparable.

Not everyone is overweight because of emotional eating. Weight gain can also happen for many other reasons like as a side effect to medication, see: basically any hormonal contraception, SSRIs, etc. The menopause/ageing, poor work life balance/life commitments and caring responsibilities. Again, a non-exhaustive list.

And finally obesity often is a lifelong issue, it will be something that we have to work on throughout the rest of our lives. There are lots of conditions and diseases which are lifelong and life limiting but they deserve attention and care for the rest of our lives as appropriate management of these conditions improves the quality of living and mitigates against developing other conditions.

You say you don't have an eating disorder, yet you say your brain gives you food noise, which presumably compels you to eat more than you should. That sounds like an eating disorder. If you haven't already, I'd speak to someone about that.

If you don't have an eating disorder, and the food noise isn't compelling you to eat more, I don't understand how this drug is supposed to help you.

2 stone on a month is probably too much, too quick, surely? Re Dh maybe just dint lentil it at all, ie don't mention what you've lost.