Please or to access all these features

AIBU?

Share your dilemmas and get honest opinions from other Mumsnetters.

Women with complete androgen insensitivity syndrome

262 replies

Tandora · 01/08/2024 17:22

https://www.nhs.uk/conditions/androgen-insensitivity-syndrome/symptoms/#:~:text=Girls%20with%20CAIS%20do%20not,make%20some%20sexual%20acts%20difficult.
Inspired by the dumpster fire of a certain thread that filled up just now -
AIBU to share some information about girls and women with CAIS. Many of these women and girls won’t learn about their variation in sex characteristics until adulthood. Some might never know and not without the assistance of modern technologies (that can test , eg, karyotype). For cases of CAIS identified at birth, most individuals are assigned/ registered/ raised female. (Yes sex can be assigned).

Anyone who could know a girl/ woman with CAIS in the real world, and tell her she is , in fact , unambiguously a boy/ man, because gametes, - well you would deserve worse than to be called a sexual fascist.

The NHS recognises the existence of girls and women with CAIS , and provides medical interventions accordingly.

https://www.nhs.uk/conditions/androgen-insensitivity-syndrome/symptoms/#:~:text=Girls%20with%20CAIS%20do%20not,make%20some%20sexual%20acts%20difficult.

https://www.ncbi.nlm.nih.gov/books/NBK1429/

Yes these conditions are rare, but the more we learn about the biology of sex development , the more complex the picture becomes, as with most areas of science/ biology/ medicine .

nhs.uk

Androgen insensitivity syndrome - Symptoms

Read more about the symptoms of androgen insensitivity syndrome (AIS), which vary depending on whether the insensitivity is partial or complete.

https://www.nhs.uk/conditions/androgen-insensitivity-syndrome/symptoms#:~:text=Girls%20with%20CAIS%20do%20not,make%20some%20sexual%20acts%20difficult.

OP posts:
MissScarletInTheBallroom · 01/08/2024 20:06

Tandora · 01/08/2024 19:31

There we go. No details what this test is. There is no scientific basis for a singular , objective, test to determine someone’s gender

There are scientific, objective tests which can be used to determine someone's sex, in the rare cases where there is any ambiguity in the matter.

There is, as you correctly state, no scientific, objective test for determining someone's gender, because gender is not scientifically, objectively real.

Ihopeithinkiknow · 01/08/2024 20:03

Cancermummy · 01/08/2024 19:12

I just want to say thank you for this thread OP. There have been some truly awful things said by people on other threads. The hatred and fear of trans people is now spreading to anyone who even tangentially fits that category.

The hatred and fear of trans people? Pretty sure this has got fuck all to do with hating trans people because why would anybody hate a group of people just because they are trans 🤨 the issue is that a woman got punched in the fucking face by a bloke. Pisses me off when the label "transphobic" gets thrown about. I am not transphobic at all but I am ablokepunchingawomanphobic. 2 completely different things and it's amazing to me that some people can't seem to understand the difference.

RedToothBrush · 01/08/2024 20:03

OP has conveniently skipped over the point about this is a matter of SAFETY. Failure to recognise that males competing in female categories pose a physical risk.

That's outrageous sexism.

Instead we are told that we are just being prejudice and unfair.

All while the OP tries to virtue signal (badly) about identity managing to be homophobic and racist in the process.

I'm sorry but some lecturing over unfairness to make competitors in this context doesn't know what the fuck they are talking about and wants to facilitate physical harm to women.

Thats seriously perverse. But hey OP is a good little 'progressive' and can say how inclusive they are...

(Rolls eyes)

Tandora · 01/08/2024 20:01

SnakesAndArrows · 01/08/2024 19:58

That’s because gender is a meaningless term.

There is no such test for sex either

OP posts:
SnakesAndArrows · 01/08/2024 19:58

Tandora · 01/08/2024 19:31

There we go. No details what this test is. There is no scientific basis for a singular , objective, test to determine someone’s gender

That’s because gender is a meaningless term.

Tandora · 01/08/2024 19:58

TheBanffie · 01/08/2024 19:53

I don't see how anyone with XY and abnormal androgen production or sensitivity could 'not know' until they were an adult - they have no womb and will never have periods. Pretty big clue in their teens that they have a medical condition that needs investigation. At an elite athlete level I flatly refuse to believe that they wouldn't know - testosterone is a drug of abuse in sport so levels are routinely checked. It's very sad that some countries choose to exploit people with DSD for sporting advantage.

I don't see how anyone with XY and abnormal androgen production or sensitivity could 'not know' until they were an adult

well that just evidences your ignorance I’m afraid. its not uncommon.
yes people may wonder when they don’t get their period , at first they may just assume they are a late developer. Then they might worry that something else is amiss but there are many other explanations for this that are much more likely than having CAIS.
Many people get to adulthood before they have the types of investigations that eventually confirm CAIS - which are only possible with modern technologies anyway.

OP posts:
SnakesAndArrows · 01/08/2024 19:56

Beth216 · 01/08/2024 19:16

The endocrinology of mammalian reproduction
David O. Norris PhD, James A. Carr PhD, in Vertebrate Endocrinology (Sixth Edition), 2021
4 Complete androgen insensitivity syndrome
A person with complete androgen insensitivity syndrome is a genetic male (46,XY) that lacks ARs. The testes are normal and secrete testosterone but do not descend from the body cavity. The testes may be removed, generally after puberty, to prevent testicular cancer in the undescended testes. Müllerian duct derivatives are absent because the embryonic testes also secreted AMH. However, the external appearance is that of a female because of the congenital absence of ARs in the tissues. This is an example of male pseudohermaphroditism.

If you have CAIS you are biologically male and your testes are internal but secrete testosterone. They may have female looking genitalia, they may choose to present as female but they are biologically male and will have the advantage of testosterone secretion.

The NHS link from the OP states that if you have CAIS you have XY chromosomes it then suggest you can be a girl with CAIS which is not genetically possible and makes no sense. It is talking about 'gender' rather than sex when it says 'girls' with CAIS I guess because it is totally captured in gender ideology.

No, CAIS means there is no sensitivity to testosterone so no huge advantage and have a female phenotype, although people with CAIS do tend to be tall.

Turophilic · 01/08/2024 19:56

Cancermummy · 01/08/2024 19:12

I just want to say thank you for this thread OP. There have been some truly awful things said by people on other threads. The hatred and fear of trans people is now spreading to anyone who even tangentially fits that category.

I don’t think anyone here hates or fears either trans people or people with DSDs. Lots of us number trans people among our friends and family.

Many of us do, however, value the safety and integrity of women’s sports (and other single sex provisions) and think those boundaries are worth defending.

TheBanffie · 01/08/2024 19:53

I don't see how anyone with XY and abnormal androgen production or sensitivity could 'not know' until they were an adult - they have no womb and will never have periods. Pretty big clue in their teens that they have a medical condition that needs investigation. At an elite athlete level I flatly refuse to believe that they wouldn't know - testosterone is a drug of abuse in sport so levels are routinely checked. It's very sad that some countries choose to exploit people with DSD for sporting advantage.

SnakesAndArrows · 01/08/2024 19:52

Cancermummy · 01/08/2024 19:12

I just want to say thank you for this thread OP. There have been some truly awful things said by people on other threads. The hatred and fear of trans people is now spreading to anyone who even tangentially fits that category.

You do understand that people with DSDs are not the same as trans people?

ExhaustedHousewife · 01/08/2024 19:49

Cancermummy · 01/08/2024 19:12

I just want to say thank you for this thread OP. There have been some truly awful things said by people on other threads. The hatred and fear of trans people is now spreading to anyone who even tangentially fits that category.

Nothing to do with trans and everything to do with dna,do your research.

Tandora · 01/08/2024 19:48

titchy · 01/08/2024 19:40

I didn’t say, nor do I believe , black men have a “genetic advantage” over white men in sport

We can read. You said:
Black men are overrepresented in many male sports. Do they have an unfair advantage because of their physiology / genetics

this is the last time I will explain myself here.
It was a question I posed to demonstrate that just because a group is over represented in sports doesn’t mean they have an unfair advantage due to physiology or genetics (which is what was being assumed re VSC),

OP posts:
SnakesAndArrows · 01/08/2024 19:47

WickieRoy · 01/08/2024 18:37

I haven't been able to face a lot of the commentary today, but a lot of the "men have penises and women have vaginas" crew have made hypocrites of themselves today.

People who have or who have ever had functional testes are men. People who have or who have ever had functional ovaries are women.

The existence of people with DSDs, who will additionally fall into either male or female category, does not negate this.

Where’s the hypocrisy ?

Tandora · 01/08/2024 19:45

titchy · 01/08/2024 19:32

I said that black men are overrepresented in male sport and lesbian women are over represented in female sports. That’s an empirical trend. Sorry if it offends you!

No. You didn't just state the empirical trend - you suggested there may be a physiological reason why more lesbians do sport:

ditalini
Jesus! That's desperate!

Actually, I'd love there to be research to investigate why lesbian girls are more likely than heterosexual girls to continue with sport as they grow. It's a much healthier way to be, both physically and mentally.

I'm guessing it's a social and community thing but you tell yourself it's in the genes if it makes you happy 😂

Your response (my bold): I’ve no doubt there is a huge social, community element. They may well also be some physiological/ hormonal factors at play. As with all differences it’s likely to be a complex mix of environmental, social, potentially physiological factors.

See also your comment on the physiology of black sports people:
Black men are overrepresented in many male sports. Do they have an unfair advantage because of their physiology / genetics?

yes , I said with regard to lesbian women in female sport ,

”I’ve no doubt there is a huge social, community element. They may well also be some physiological/ hormonal factors at play. As with all differences it’s likely to be a complex mix of environmental, social, potentially physiological factors”.

I stand by that. That doesn’t mean I think gay women are physiologically diff to straight women, but there is research that shows that women in sport have higher levels of testosterone. There is also some reaearxh that suggests that lesbian women may generally on average have higher levels of testosterone than straight women (eg . www.sciencedirect.com/science/article/abs/pii/S0306453016301846#:~:text=Sex%20hormone%20differences%20among%20diverse,lesbian%2Fbisexual%20than%20heterosexual%20women.) This is obviously massively complex and I certainly am not claiming to know the facts/ have the answers here!!!! But it’s not a ludicrous or homophobic proposition, although I know you want to make it out to be.

OP posts:
sunflower1022 · 01/08/2024 19:42

This thread is nuts

titchy · 01/08/2024 19:40

I didn’t say, nor do I believe , black men have a “genetic advantage” over white men in sport

We can read. You said:
Black men are overrepresented in many male sports. Do they have an unfair advantage because of their physiology / genetics

SnakesAndArrows · 01/08/2024 19:39

WednesburyUnreasonable · 01/08/2024 18:21

Presumably the people insistent that women with Swyer syndrome (most of whom have a uterus) are definitely men will no longer be objecting to “women and people with X” terminology then.

People with Swyer syndrome are genetically male but have a female phenotype, like people with CAIS. They are considered women, for obvious reasons.

C’mon this isn’t difficult.

MissScarletInTheBallroom · 01/08/2024 19:38

whattywhattaa · 01/08/2024 17:34

But most people have a genetic advantage one way or another.

Big feet, long legs, height.

50% of people have the genetic advantage of having testes which produce large quantities of testosterone, thus vastly improving sporting performance.

That's the main reason why we have separate categories for male and female athletes.

nameynamenamenamename · 01/08/2024 19:37

So do please tell us @Tandora

What do you believe are the “physiological/ hormonal factors at play” that make lesbians different?

Tandora · 01/08/2024 19:37

nameynamenamenamename · 01/08/2024 19:28

Yes, I do have issue with your “black and white” reasoning.

The suggestion that black men, as a group, have a genetic advantage over white men has long been debunked as racist scaremongering.

I have no idea who you are arguing with but it’s not me. I didn’t say, nor do I believe , black men have a “genetic advantage” over white men in sport (nor would I give a flaming toss if they did but that’s by the by). I said black people are over-represented in sports which they are. in the same way, women with sex variations are over represented in female sports- this doesnt mean they have a “genetic advantage”. pP on this thread are suggesting as if one automatically implies the other.

Anyway there’s no point in defending myself against fabricated points of argument.

OP posts:
WickedSerious · 01/08/2024 19:35

LoobyDoop2 · 01/08/2024 19:28

Hear, hear. Thank goodness there are people with the courage to stand up and defend the right of men to beat women to a pulp and then claim the medals that were intended for those women. You are a beacon of hope in a cruel, cruel world that doesn’t always condone male violence against women as blatantly as it could.

Yep,it's a dirty job but someone had to do it.

needmoresheep · 01/08/2024 19:33

What’s this about lesbians? Has there been a survey conducted on our Olympic team and others to show an ‘over representation’ of lesbians?

what a load of nonsense!

titchy · 01/08/2024 19:32

I said that black men are overrepresented in male sport and lesbian women are over represented in female sports. That’s an empirical trend. Sorry if it offends you!

No. You didn't just state the empirical trend - you suggested there may be a physiological reason why more lesbians do sport:

ditalini
Jesus! That's desperate!

Actually, I'd love there to be research to investigate why lesbian girls are more likely than heterosexual girls to continue with sport as they grow. It's a much healthier way to be, both physically and mentally.

I'm guessing it's a social and community thing but you tell yourself it's in the genes if it makes you happy 😂

Your response (my bold): I’ve no doubt there is a huge social, community element. They may well also be some physiological/ hormonal factors at play. As with all differences it’s likely to be a complex mix of environmental, social, potentially physiological factors.

See also your comment on the physiology of black sports people:
Black men are overrepresented in many male sports. Do they have an unfair advantage because of their physiology / genetics?

montysma1 · 01/08/2024 19:32

Tandora · 01/08/2024 19:14

Please tell me what the test consists of, and the science that endorses it as an objective, valid and reliable method to test someone’s gender.

Edited

That would be "determining their sex". Gender is irrelevant to sporting performance.

Sex however is relevant.
As you have been told many times, male puberty , which happens to men not women, causes irreversible physical development of a male body, which confers sporting advantage.

How many times?

FOJN · 01/08/2024 19:32

Tandora · 01/08/2024 19:13

Did you read the OP? Karyotype doesn’t necessarily define what sex category you are in.
And I do think it’s a human right not to be arbitrarily excluded from sporting competitions because of an identity characteristic

Edited

Karyotype does determine your sex category.

DSD's are not identities, they are medical conditions, some of which can have significant health implications for the person affected. If you weren't so determined to exploit DSD's in your "sex is a spectrum" argument, which ultimately leads to men dominating womens sport, you might have researched more than CAIS and have some genuine compassion for people with other types of DSD.

You trivialise the meaning of the term "human rights" when you apply it to the right to compete in the sports team/category of your choosing at elite level. You are being ridiculous.

Swipe left for the next trending thread