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Women with complete androgen insensitivity syndrome

262 replies

Tandora · 01/08/2024 17:22

https://www.nhs.uk/conditions/androgen-insensitivity-syndrome/symptoms/#:~:text=Girls%20with%20CAIS%20do%20not,make%20some%20sexual%20acts%20difficult.
Inspired by the dumpster fire of a certain thread that filled up just now -
AIBU to share some information about girls and women with CAIS. Many of these women and girls won’t learn about their variation in sex characteristics until adulthood. Some might never know and not without the assistance of modern technologies (that can test , eg, karyotype). For cases of CAIS identified at birth, most individuals are assigned/ registered/ raised female. (Yes sex can be assigned).

Anyone who could know a girl/ woman with CAIS in the real world, and tell her she is , in fact , unambiguously a boy/ man, because gametes, - well you would deserve worse than to be called a sexual fascist.

The NHS recognises the existence of girls and women with CAIS , and provides medical interventions accordingly.

https://www.nhs.uk/conditions/androgen-insensitivity-syndrome/symptoms/#:~:text=Girls%20with%20CAIS%20do%20not,make%20some%20sexual%20acts%20difficult.

https://www.ncbi.nlm.nih.gov/books/NBK1429/

Yes these conditions are rare, but the more we learn about the biology of sex development , the more complex the picture becomes, as with most areas of science/ biology/ medicine .

nhs.uk

Androgen insensitivity syndrome - Symptoms

Read more about the symptoms of androgen insensitivity syndrome (AIS), which vary depending on whether the insensitivity is partial or complete.

https://www.nhs.uk/conditions/androgen-insensitivity-syndrome/symptoms#:~:text=Girls%20with%20CAIS%20do%20not,make%20some%20sexual%20acts%20difficult.

OP posts:
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Ereshkigalangcleg · 02/08/2024 17:02

No they're not!!! Cheek swab tests to determine sex were discontinued in 2000 - they were in use from 1968!!

And apparently 82% of female athletes voted to continue them at the time, but were ignored.

BreatheAndFocus · 02/08/2024 15:39

whattywhatt · 02/08/2024 14:49

Now you are just being pendantic. There has been cases. So what would you call them then? A man still?

No, I’m not. I didn’t know what type you’re referring to. I was talking about 5-ard, a DSD affecting males. You said what if they have “the type” where they can have a baby? I asked you to clarify which DSD you were talking about.

And, just to be clear, being female isn’t reliant on having a baby. Infertile women or women who are childless by choice are female/women.

If someone has a DSD and a fully present and functioning female reproductive system, they’d be female. But they’d only have a ‘mild’ DSD because DSDs usually affect fertility.

CleftChin · 02/08/2024 15:00

These genetic tests are only fairly recent. How far back shall we go?

No they're not!!! Cheek swab tests to determine sex were discontinued in 2000 - they were in use from 1968!!!

ditalini · 02/08/2024 14:54

whattywhatt · 02/08/2024 14:49

Now you are just being pendantic. There has been cases. So what would you call them then? A man still?

Are you talking about Swyer syndrome where a person is born with XY chromosomes but no sry gene, so no testicles, no virilisation via testosterone, no male puberty?

These women have a fully functioning female reproductive tract but no ovaries so can sometimes conceive and give birth via donor eggs and IVF.

If it's Swyer, then they'd be an absolutely bog standard woman in sporting advantage terms and none of this would ever have arisen.

whattywhatt · 02/08/2024 14:49

Now you are just being pendantic. There has been cases. So what would you call them then? A man still?

BreatheAndFocus · 02/08/2024 14:42

whattywhatt · 02/08/2024 14:38

Ok but would that change if an athelete had the type where they could?

What do you mean by “the type”? There are a number of DSDs. Many (most?) cause issues with fertility.

whattywhatt · 02/08/2024 14:38

BreatheAndFocus · 02/08/2024 14:37

It’s being suggested that Khelif might have 5-ard due to the way the tests are being reported. If that were the case, they would be male and wouldn’t be able to conceive or give birth.

Ok but would that change if an athelete had the type where they could?

outdamnedspots · 02/08/2024 14:37

summerdazey · 01/08/2024 17:27

I think this is really important information for people to read. It isn't as uncommon as people may imagine.

0.018% of people have a DSD. It is pretty rare.

whattywhatt · 02/08/2024 14:37

Ereshkigalangcleg · 02/08/2024 14:32

She is not a man! She could potentially give birth and woman have.

Who says? We don't know the condition. Link please.

No exactly but its as though everyone is jumping on like trans comoeo( which am
all against ) but this is completely different.

These genetic tests are only fairly recent. How far back shall we go?

www.boxingscene.com/misunderstanding-imane-khelifs-past-present--185133

BreatheAndFocus · 02/08/2024 14:37

It’s being suggested that Khelif might have 5-ard due to the way the tests are being reported. If that were the case, they would be male and wouldn’t be able to conceive or give birth.

Ereshkigalangcleg · 02/08/2024 14:32

She is not a man! She could potentially give birth and woman have.

Who says? We don't know the condition. Link please.

whattywhatt · 02/08/2024 14:19

Naunet · 02/08/2024 13:48

Oh for god sake, are some people still trying to convince us all that it’s fine for men to hit women?

She is not a man! She could potentially give birth and woman have.

I would totally agree with you if was a man born and changed but she wasn't and I think you arw being disingenuous at best and abelist.

Turophilic · 02/08/2024 14:11

Naunet · 02/08/2024 13:48

Oh for god sake, are some people still trying to convince us all that it’s fine for men to hit women?

Apparently so. Ludicrous, isn’t it?

Naunet · 02/08/2024 13:48

Oh for god sake, are some people still trying to convince us all that it’s fine for men to hit women?

JaneJeffer · 02/08/2024 13:39

you've created a thread about a thread
Seems MN is fine with this now so I look forward to being able to do the same in future.

They were excluded from boxing championships last year; a decision which the Olympic committee has called arbitrary.
I wonder what they think about their decision to let them compete now.

coffeeandteav · 02/08/2024 11:26

titchy · 02/08/2024 10:08

I also don't think that not fitting neatly into male means you get into female. I think the opposite, even if your DSD makes you weaker than other men and/or you think you are a woman, if you don't fit neatly into the female box you compete in the open category.

Male with unusual phenotype does not = female.

We wouldn't know if it wasn't for these tests. I wonder if it has happened in the past but been unaware as the person has female reproductive organs.

titchy · 02/08/2024 10:08

I also don't think that not fitting neatly into male means you get into female. I think the opposite, even if your DSD makes you weaker than other men and/or you think you are a woman, if you don't fit neatly into the female box you compete in the open category.

Male with unusual phenotype does not = female.

BreatheAndFocus · 02/08/2024 09:57

There’s no suggestion that either of these boxers have CAIS. The IOC seems to think their passports are enough, which is ridiculous.

People with DSDs need specific rules, eg the ones around Semenya and others with 5-ard, but basically no male person should be in a competition for females. The OP mentions CAIS. That’s an area of disagreement as far as I understand, but neither of these boxers are believed to have CAIS.

IMO, it would be better to release information - with the agreement of the competitor obviously - because that would stop the speculation. It would also stop blatant lies and propaganda, as well as the use of racist tropes.

LittleLittleRex · 02/08/2024 08:46

I would be happy to agree that some people don't fit neatly into male and female categories.

I also don't think that not fitting neatly into male means you get into female. I think the opposite, even if your DSD makes you weaker than other men and/or you think you are a woman, if you don't fit neatly into the female box you compete in the open category.

Female is the protected characteristic and these boxers do not meet the criteria, it is that simple.

Every day, all over the world, people are receiving diagnoses that limit their life and what they can do. I don't see any reason why males with DSDs can't have their limitations spelt out to them as well - they'll cope.

IkaBaar · 02/08/2024 08:38

Tandora · 01/08/2024 19:13

Did you read the OP? Karyotype doesn’t necessarily define what sex category you are in.
And I do think it’s a human right not to be arbitrarily excluded from sporting competitions because of an identity characteristic

Edited

But what about the rights of the other competitors to fight against other females? People will be excluded from elite sport for many reasons, maybe they need medication that is a performance enhancing drug, but it’s not one they can get a therapeutic exemption for. Should Russian athletes have the right to compete, I’m sure they all are not personally responsible for the war in Ukraine, what about their rights?

Khelif probably has a DSD. It is hard to believe that Khelif and his family, coaches and the Algerian boxing association and Algerian Olympic association don’t know that he has a DSD. It must be hard to have a DSD in a country where they aren’t routinely picked up at birth, however that doesn’t give him the right to fight against women. The corrupt IOC do have a lot to answer for in allowing this situation to even occur. A once in a lifetime sex test, would have prevented this. A check swab is all that is needed.

Sharron Davies’ book Unfair play, the battle for women’s sport is an excellent read. Sharron competed in the era of state sponsored doping in East Germany (and other countries) so was cheated out of medals by women who were pumped up on testosterone.

ChazsBrilliantAttitude · 02/08/2024 08:30

and contradicts the physiology of sex development , science, medicine, law and the self knowledge of women and girls living with CAIS.

Which specific laws were you thinking about? You make broad assertions so feel free to link peer reviewed research on the legal status of people with CAIS.

These areas of law are hugely complex as they involve an intersection of rights. Sex is a protected characteristic under the Equality Act and the ordinary meaning of the word would mean genetics.

Tandora · 02/08/2024 08:20

BreatheAndFocus · 02/08/2024 08:19

Yes, I chose Klinefelters as a simple one to illustrate my point. It’s more difficult with something like PAIS where the presentation can vary. In those cases, judgement has to be used. Not just a ‘social’ judgement, but medical judgements about how the external genitalia will develop, removal of any internal testes, hormone treatment.

Correct

OP posts:
BreatheAndFocus · 02/08/2024 08:19

Tandora · 02/08/2024 08:12

They don’t go, “Well, this person has A, B and C, so that equals Klinefelters. Now, are they male or female?” 🤔 All people with Klinefelters are male.

that is now the consensus around people with Klinefelters yes (it wasn’t always the consensus). But there are many other conditions where the situation isn’t clear cut , and deciding whether that person should be assigned male or female is exactly what medics need to do. The decision to assign someone’s sex in itself, of course, isn’t simply about whether they are properly described as male or female, that’s an even trickier question, and no, there isn’t any scientific consensus are a test , or sequencing of tests, to determine this.

Yes, I chose Klinefelters as a simple one to illustrate my point. It’s more difficult with something like PAIS where the presentation can vary. In those cases, judgement has to be used. Not just a ‘social’ judgement, but medical judgements about how the external genitalia will develop, removal of any internal testes, hormone treatment.

Tandora · 02/08/2024 08:18

ChazsBrilliantAttitude · 02/08/2024 08:10

Someone with CAIS is male. They may present as female but genetically they are male. If a way was found to induce androgen sensitivity they would go through male puberty not female.

Someone with CAIS is male. No. Somebody with CAIS has a male karyotype, that is all you can accurately say. The assumption that having a male karyotype is sufficient to make a person male is entirely yours , and contradicts the physiology of sex development , science, medicine, law and the self knowledge of women and girls living with CAIS.

If a way was found to induce androgen sensitivity they would go through male puberty not female

but there isn’t, so they didn’t!
It’s like saying, “well if we could cure autism, then autistic people would be neurotypical”!

OP posts:
ChazsBrilliantAttitude · 02/08/2024 08:18

I think there are two separate issues an individual one and a societal one.

On an individual level people with CAIS should be free to live their lives in a way that matches how they present.

On a societal level redefining the concepts of woman and female to include people with XY chromosomes has implications far beyond CAIS, so the existence CAIS is only a small consideration in a very much bigger picture.