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AIBU?

Share your dilemmas and get honest opinions from other Mumsnetters.

To just remind you that autism is genetic?

261 replies

robotgun · 02/07/2024 16:05

Research tells us that 60 to 90% of the risk for autism comes from your genome. Maternal and paternal age are also a significant factor. Also genetic variants exist that cause autism-like behaviours and go undiagnosed because we don't routinely run genetic tests on our children. We also don't routinely institutionalise children that are different to their peers.

There's 'more' autism because people are having babies at older ages. And we are better at spotting autism.

It isn't heavy metals, microplastics, or the MMR.

Sorry, but it seems like every day I open this app and there's a new post saying 'What's going on with all this autism around, eh?' and a slew of replies blaming environmental factors that have no science behind them whatsoever. Or, worse, blaming mothers for reproducing too late in life or eating tuna in pregnancy or taking prescribed meds.

If you see enough of these threads every day you could well start to believe the nonsense that people write, much like people that read the Daily Mail every day start to believe that Meghan Markle is the devil.

Autism has always been here. It's not better or worse than it used to be.

OP posts:
LiterallyOnFire · 02/07/2024 17:20

fliptopbin · 02/07/2024 17:18

Surely another factor in the perceived increase is that until recently the diagnostic criteria was based solely on the way autism typically presents in males (because of course it did), so it seemed that autistic females barely existed.

👏🏻 👏🏻 👏🏻

LiterallyOnFire · 02/07/2024 17:20

Both of us have ND parents who would/will never be diagnosed.

My dad is the same. It's a shame more of that generation won't cooperate. It would make things so much clearer.

Riversideandrelax · 02/07/2024 17:19

RatHole · 02/07/2024 16:36

Most of my family are on the autism spectrum.

Having had a child suffer side effects from a prescribed drug and seen first hand how the pharmaceutical companies close ranks and deny I’ve lost my faith in them and no longer trust them to be honest. I was going to be part of an exposè in a National newspaper, I talked to a journalist and a doctor about this, but they were later warned to not discuss it and the article was dropped.

Thousands of people a week join the support group for this drug so it’s still ongoing. The company conceded to add the side effects to the drug info several years ago, but refuse to support any research, so any medical findings are down to patient groups who have done the work.

My autistic son went from being fine and supportable to being very high needs, unable to go to school and needing an awful lot of support.

I suspect more children’s/people’s autism is more disabling to them and their families because of certain pharmaceutical and dietary factors but the might of these huge corporations keeps it well under wraps and parents who talk about this are dismissed as conspiracy theorists or stupid.

I think a lot will come out about certain pharmaceutical products in the next 10-20 years. There are already films about certain coverups (Dopesick, Painkiller, Dark Waters). There will be more to come.

Can you say what drug?

TheThreeCheesesOfTheApocalypse44 · 02/07/2024 17:18

Y

fliptopbin · 02/07/2024 17:18

Surely another factor in the perceived increase is that until recently the diagnostic criteria was based solely on the way autism typically presents in males (because of course it did), so it seemed that autistic females barely existed.

Alltheyearround · 02/07/2024 17:18

RatHole · 02/07/2024 16:36

Most of my family are on the autism spectrum.

Having had a child suffer side effects from a prescribed drug and seen first hand how the pharmaceutical companies close ranks and deny I’ve lost my faith in them and no longer trust them to be honest. I was going to be part of an exposè in a National newspaper, I talked to a journalist and a doctor about this, but they were later warned to not discuss it and the article was dropped.

Thousands of people a week join the support group for this drug so it’s still ongoing. The company conceded to add the side effects to the drug info several years ago, but refuse to support any research, so any medical findings are down to patient groups who have done the work.

My autistic son went from being fine and supportable to being very high needs, unable to go to school and needing an awful lot of support.

I suspect more children’s/people’s autism is more disabling to them and their families because of certain pharmaceutical and dietary factors but the might of these huge corporations keeps it well under wraps and parents who talk about this are dismissed as conspiracy theorists or stupid.

I think a lot will come out about certain pharmaceutical products in the next 10-20 years. There are already films about certain coverups (Dopesick, Painkiller, Dark Waters). There will be more to come.

Could you PM me and tell me what it is?

RatHole · 02/07/2024 17:17

robotgun · 02/07/2024 17:04

I agree @RatHole but only if a strong enough link has been made. It's beyond doubt now that drinking in pregnancy can cause certain conditions in babies. We aren't there with autism, and until that link is strong enough it just becomes a stick to bash people with.

Yes you’re right, and usually mothers!

Amongst the community though there seems to be a real problem with even suggesting things that may ease the symptoms (not the right word but I can’t think of the right one) and equate it to some sort of autism genocide, which is ridiculous. People seem very defensive.

For example - if I eat a very low carb diet my sensory issues basically go away. I don’t get overwhelmed by noise, I’m better at dealing with normal everyday stress. If I say that in certain places I’m shot down and told I’m irresponsible for saying that as they think I’m suggesting there’s a cure for autism, that it’s pseudoscience, that I’m basically Hitler etc. All I’ve done is say how low carb affects me positively, and maybe that can help others live easier lives. I know others who eat a similar diet for the same reasons, but now we tend to keep it to ourselves which is a shame.

Razorwire · 02/07/2024 17:17

The definition of AUTISM is wide open, it really depends on context.
NHS broadly says:
Autism, also called autism spectrum disorder (ASD), is a lifelong, developmental condition. It affects the way a person communicates, interacts and processes information.

Given that definition … most people with a syndrome, learning difficulty, etc can be defined as Autistic if the have communication & “processing” difficulties.

Consider the child w ehcp who was at Autism special school in our area, he was there, doing well, for 4 years. Yup, autism. He then got a Geneticist diagnosis of a rare chromosome Syndrome. The parents included this new info in the ehcp and the school said “he doesn’t have autism” and he needed to leave. He had the exact same communication and processing probs but paper pushers said Buh-bye this is Autism-only school. Parents said wished they had kept mouths shut.

Autism is a huge bucket that many many are put into.
IMO - in time, there will be many many subtypes of Autism with chromosomal causes. They are not all the same, rarely even similar.

FailBetter · 02/07/2024 17:16

robotgun · 02/07/2024 17:01

No, it's not easier or harder, just you are either autistic or not. Some diagnoses still contain levels. So I have the diagnosis of meeting criteria under DSM, level 1. My DS has a level 2 diagnosis.

Those with Asperger syndrome or “pervasive developmental disorder, not otherwise specified,” endured some of the same social struggles as those with autism but now no longer meet the definition. The proposed change consolidated all three diagnoses under one category, autism spectrum disorder, eliminating Asperger syndrome and P.D.D.-N.O.S. from the manual. Under the old criteria, a person would qualify for the diagnosis by exhibiting 6 or more of 12 behaviours; now the person has to exhibit 3 deficits in social interaction and communication and at least 2 repetitive behaviours, a much narrower menu.

There is debate as to whether the definitions were changed simply to appease those who associated Asperger with eugenics or to actually bring down the number of diagnoses in the U.S. at the time (which was increasing). Now the UK has the most number globally.

Marscapn3 · 02/07/2024 17:15

widowedm · 02/07/2024 17:06

Interesting.

As a mental health professional, I can safely say my parents are not autistic and do not show any neurodivergent traits. My parents were 19/20 when they had my sibling and 21 when they had me.

My eldest sibling is severely autistic.
I have ADHD.

We both have childhood trauma (physical and mental) which I can safely say triggered OCD (diagnosed) and I believe neurodivergence is closely linked to trauma.

Likewise there are a lot of misdiagnosed children, who aren't autistic- they're traumatised.

And lots of undiagnosed children/adults.

More research is needed and less finger pointing.

There isn't "more" neurodivergence. Looking back to childhood, there were a lot of kids in my class who I bet were neurodivergent but not diagnosed.

We have more testing and more awareness. Not more autism.

No neurodivergence isn’tlinked to trauma but neurodiverse individuals may be at increased risk to trauma.Trauma symptoms can exacerbate neurodiverse traits.

Where are your links re misdiagnosed children having trauma not autism?

I don’t think being a mental health professional
means anything to be honest.Some of the most ignorant as regards neurodiversity have been those we’ve had the misfortune to meet in the mental health field.

Also neurodiversity can skip generations.

Hb7x3 · 02/07/2024 17:14

JustHereWithMyPopcorn · 02/07/2024 16:34

The age thing I thought was more linked to father's age rather than mother?

Little sperms with their walking sticks and flat caps

Riversideandrelax · 02/07/2024 17:14

KeirSpoutsTwaddle · 02/07/2024 16:28

The increase is far greater than simply diagnosis. Apart from anything else, DH’s extended family aren’t actually diagnosed despite being pretty clearly autistic.

We aren’t giving a new label to existing behaviours. We are seeing massive increases in primary children struggling to cope at school.

Either the world has changed so much that people who used to cope no longer can- which is perfectly possible - or there are far more children with autism than there used to be, perhaps because of different ways of socialising.

Part of that is lots of DC being put in mainstream when they need a special school.

MsCactus · 02/07/2024 17:13

robotgun · 02/07/2024 17:11

I'm not denying the fathers age link @MsCactus, that's been studio and recognised too

Yeah I know. I just think autism is one of the rare ones that from what I've seen a mother's age doesn't influence - which I welcome because tbh they seem to blame everything on a mother's age rather than the father's age

robotgun · 02/07/2024 17:11

I'm not denying the fathers age link @MsCactus, that's been studio and recognised too

OP posts:
robotgun · 02/07/2024 17:10

Londonwriter · 02/07/2024 17:08

I spoke to a scientist about this. There are three main ‘causes’ of autism - two which cause intellectual disability, and one which doesn’t.

The first (Group 1) is a massive genetic mutation (or major congenital damage), which leads to children with major intellectual disability, epilepsy, etc. etc These are children who get diagnosed very early, end up in special school, and have very high support needs into adulthood. They are largely in families with no history of autism.

The second (Group 2) are ‘copy number’ genetic variations. These cause mild intellectual disability, but - again - largely aren’t uncomplicated inherited from parents. Again, the kids usually end up in special school and often have co-associated conditions.

The third (Group 3) is where the kids have inherited autistic traits from one, or more, family members. Increasingly, these kids get diagnosed in childhood and you’ll find whole families where every child, or almost every child, has a diagnosis of ADHD, autism or both. These children are healthy, of average, or above average, intelligence, and they usually have an autistic parent or grandparent. They don’t have any co-associated conditions that aren’t shared with a family member (i.e. if you get arthritis or migraines, your kids probably will).

It turns out there’s vastly more Group 3 than Groups 1 & 2, probably 10x more, but most adults in Group 3 were never diagnosed. About a third of diagnosed-autistic adults aged 30-50 registered with GPs in the UK have a learning disability. Only 10% of autistic children diagnosed under 10 do (90% don’t).

As such, there’s now a huge fight within the autism community between parents of kids in Groups 1 & 2, who view autism as a disaster that needs curing, and families of people where literally everyone is autistic (or ‘broader autistic phenotype’), who see themselves as ‘neurodivergent’, and simply requiring some adjustments to live a happy, productive life.

Most research was done on people who are now adults and, as such, most autism resources assume the vast majority of autistic people have learning disabilities. This isn’t the situation on the ground and it’s obvious that researchers haven’t yet caught up. Some of the increased diagnosis is due to changing classroom settings (e.g. talking in class for group work) along with powerful noisy new technologies, such as Dyson hand driers, which many autistic kids struggle with.

My DS would be group 1 in this case and me and DH group 3. Both of us have ND parents who would/will never be diagnosed.

OP posts:
MsCactus · 02/07/2024 17:10

robotgun · 02/07/2024 17:06

It's sometimes hard to sort the wheat from the chaff in these debates but this is a good place to start www.scientificamerican.com/article/autism-maternal-age/

I don't think this study has tracked fathers ages - or has it? They're finding now that a lot of disorders they linked to higher maternal age are actually due to father paternal age, and once you account for that the mother's age has no impact.

It's just sexism in research. But the rigorous studies have found only a link with autism and fathers age afaik - happy to be proven wrong if there's evidence to the contrary

Londonwriter · 02/07/2024 17:08

I spoke to a scientist about this. There are three main ‘causes’ of autism - two which cause intellectual disability, and one which doesn’t.

The first (Group 1) is a massive genetic mutation (or major congenital damage), which leads to children with major intellectual disability, epilepsy, etc. etc These are children who get diagnosed very early, end up in special school, and have very high support needs into adulthood. They are largely in families with no history of autism.

The second (Group 2) are ‘copy number’ genetic variations. These cause mild intellectual disability, but - again - largely aren’t uncomplicated inherited from parents. Again, the kids usually end up in special school and often have co-associated conditions.

The third (Group 3) is where the kids have inherited autistic traits from one, or more, family members. Increasingly, these kids get diagnosed in childhood and you’ll find whole families where every child, or almost every child, has a diagnosis of ADHD, autism or both. These children are healthy, of average, or above average, intelligence, and they usually have an autistic parent or grandparent. They don’t have any co-associated conditions that aren’t shared with a family member (i.e. if you get arthritis or migraines, your kids probably will).

It turns out there’s vastly more Group 3 than Groups 1 & 2, probably 10x more, but most adults in Group 3 were never diagnosed. About a third of diagnosed-autistic adults aged 30-50 registered with GPs in the UK have a learning disability. Only 10% of autistic children diagnosed under 10 do (90% don’t).

As such, there’s now a huge fight within the autism community between parents of kids in Groups 1 & 2, who view autism as a disaster that needs curing, and families of people where literally everyone is autistic (or ‘broader autistic phenotype’), who see themselves as ‘neurodivergent’, and simply requiring some adjustments to live a happy, productive life.

Most research was done on people who are now adults and, as such, most autism resources assume the vast majority of autistic people have learning disabilities. This isn’t the situation on the ground and it’s obvious that researchers haven’t yet caught up. Some of the increased diagnosis is due to changing classroom settings (e.g. talking in class for group work) along with powerful noisy new technologies, such as Dyson hand driers, which many autistic kids struggle with.

mickybarrysmum · 02/07/2024 17:07

My son is diagnosed asd my husband is exploring this now and seems to be struggling later in life, my mother in law and husbands grandad also both undiagnosed but very clearly asd.
Husbands grandad is 98 mother in law 70 they were never tested but their autisim is plain to see there isn't more autism just more awareness 🙌 I understand what you meant.

Riversideandrelax · 02/07/2024 17:07

raffegiraffe · 02/07/2024 16:46

I think ssri exposure in utero is being postulated also

What is SSRI?

widowedm · 02/07/2024 17:06

Interesting.

As a mental health professional, I can safely say my parents are not autistic and do not show any neurodivergent traits. My parents were 19/20 when they had my sibling and 21 when they had me.

My eldest sibling is severely autistic.
I have ADHD.

We both have childhood trauma (physical and mental) which I can safely say triggered OCD (diagnosed) and I believe neurodivergence is closely linked to trauma.

Likewise there are a lot of misdiagnosed children, who aren't autistic- they're traumatised.

And lots of undiagnosed children/adults.

More research is needed and less finger pointing.

There isn't "more" neurodivergence. Looking back to childhood, there were a lot of kids in my class who I bet were neurodivergent but not diagnosed.

We have more testing and more awareness. Not more autism.

robotgun · 02/07/2024 17:06

Riversideandrelax · 02/07/2024 17:04

I've never heard anything about age. Can you say more about that? What sort of age are we talking and how much does it effect things? It doesn't ring true from my experience but of course that's anecdotal.

It's sometimes hard to sort the wheat from the chaff in these debates but this is a good place to start www.scientificamerican.com/article/autism-maternal-age/

OP posts:
TattiePants · 02/07/2024 17:05

I'm involved with a children's disability charity and have a DC of my own with SEN (although not ASD). Genetics plays a huge part and many of our families can trace ASD back through their family tree although it's often only once a child has been diagnosed that everything slots into place. I had no idea that my DF probably has undiagnosed SEN until my DS was struggling as he'd learned to mask. Most of us will remember the 'weird' kid at school who may well have had SEN.

Other factors likely to contribute are increase in parental age (generally thought to be DF's age as opposed to DM's age although the two are often linked). Premature and disabled DC surviving that wouldn't have survived previously. There are also social factors like more women going into previously 'male' STEM jobs or university courses. Some of those women will have ASD, meet men also with ASD and go on to have DC with ASD. The internet has also provided a way for people with ASD who might struggle socially or have niche interest etc to meet online then get together and have DC.

Clarice99 · 02/07/2024 17:05

BoobyDazzler · 02/07/2024 16:13

I’ve literally never seen anyone say most of the stuff you’ve claimed to see with the expecting perhaps of vaccine damage concern in the Andrew Wakefield era.

Perhaps you're not reading the same threads as the OP.

I see it regularly and I'm not on here daily.

MsCactus · 02/07/2024 17:05

I'm pretty certain it's only fathers ages that makes a difference to autism. Not mother's age
There's loads of reputable studies on this - I can't be bothered to post them but have posted them on other similad threads

robotgun · 02/07/2024 17:05

Andthereitis · 02/07/2024 17:03

My DH always says that if we ever had to survive in the wild our autistic DC would thrive and we would all perish 😂

OP posts: