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To just remind you that autism is genetic?

261 replies

robotgun · 02/07/2024 16:05

Research tells us that 60 to 90% of the risk for autism comes from your genome. Maternal and paternal age are also a significant factor. Also genetic variants exist that cause autism-like behaviours and go undiagnosed because we don't routinely run genetic tests on our children. We also don't routinely institutionalise children that are different to their peers.

There's 'more' autism because people are having babies at older ages. And we are better at spotting autism.

It isn't heavy metals, microplastics, or the MMR.

Sorry, but it seems like every day I open this app and there's a new post saying 'What's going on with all this autism around, eh?' and a slew of replies blaming environmental factors that have no science behind them whatsoever. Or, worse, blaming mothers for reproducing too late in life or eating tuna in pregnancy or taking prescribed meds.

If you see enough of these threads every day you could well start to believe the nonsense that people write, much like people that read the Daily Mail every day start to believe that Meghan Markle is the devil.

Autism has always been here. It's not better or worse than it used to be.

OP posts:
LostTheMarble · 02/07/2024 18:26

Foxxo · 02/07/2024 18:22

Its something i warn people about as an adult with AuDHD.

late diagnosis and use of medication as an adult, is going to suddenly hand your Autism the rudder, and you will be at sea with your Autism in charge and it doesn't know how to steer the boat.

I ended up giving up my adhd meds, my brain is quieter on them but my autism was suddenly catapulted front and center, and my mood and sensory regulation abilities went totally out the window.

Edited

This is something I’m seriously concerned about in perusing an adult adhd diagnosis. I fully suspect autism in deeply buried under there (teenage me these days would have been diagnosed with both but I’ve learned to socially mask greatly since), but ADHD is fully at the wheel. It’s becoming increasingly detrimental to my life though, my brain is fried and I can no longer focus enough to do anything I used to enjoy, like reading.

RatHole · 02/07/2024 18:25

robotgun · 02/07/2024 17:36

This is the sort of BS I was hoping to avoid on this thread.

BS? Really?
People having real improvements and you’re calling it BS?

I have moved away from parts of the autism community because of shit like this, along with many others.

The absolute denial that we can take some responsibility for our own experiences and outcomes. There seems to be a real attachment to victimhood and not having any control over our own lives in too many groups, which is really unhealthy for us and for our children.

Yes autism is largely genetic/heritable, but there is a huge head in sand affect that there is anything we can do to improve our lives. I get that there are parents out there going to extremes and giving their children bleach enemas, electric shock therapy etc, but tweaking a diet is not on this level and shouldn’t be written off as such. It’s alienating to an awful lot of people who know that it works for them.

Calling another poster’s experience BS - I mean, wtf! Who are you to dismiss a benign method that is working for lots of people, whether you want it to or not!

hotandpremeni · 02/07/2024 18:24

Also has anyone watched sweet tooth series and their brains made the link between how the hybrids/kids are treated as the problem and prevailers of all things bad and cause of the sickness when actually the problem wasn't them.

Sorry weird tangent. Personally I don't want to cure my ASD my life in someways seems less complicated than my NT counter parts tbh.

Buddysbunda · 02/07/2024 18:23

Autism runs through dhs family but went unknown before this latest generation where the majority of his nieces/nephews and our children have been diagnosed with either autism, adhd or both. When you look at the other generations it seems obvious now knowing what we know but they were all oblivious until their own children started getting diagnosed.

Oh and they all pretty much exclusively started having children in their 20s so age wasn't a factor there.

Foxxo · 02/07/2024 18:22

PurpleBugz · 02/07/2024 17:32

@RatHole

I agrée with you re food! People don't want to hear it but there are lots of us who do see correlations. I cook from scratch and try not to use processed food. When I do my child's autistic traits are much much more obvious and challenging. I feel better in myself if I cut the carbs and processed food too.

There is also medication. I'm ADHD as well as autistic. Was in my 20s when diagnosed so got through school struggling but without meds. Well ADHD meds they do like to hand out SSRIs (which absolutely make me worse and more obviously have needs) But I tried meds as an adult. Yes my brain could focus that was amazing but dear god it highlighted all my sensory issues and made me much more obviously autistic. Now I'm mes free and clean eating, im still autistic but the level of struggles is vastly reduced

Its something i warn people about as an adult with AuDHD.

late diagnosis and use of medication as an adult, is going to suddenly hand your Autism the rudder, and you will be at sea with your Autism in charge and it doesn't know how to steer the boat.

I ended up giving up my adhd meds, my brain is quieter on them but my autism was suddenly catapulted front and center, and my mood and sensory regulation abilities went totally out the window.

hotandpremeni · 02/07/2024 18:18

Cymbalssymbols · 02/07/2024 17:51

Well said OP. Just wanted to add my opinion to this. I don't think autism is created more often by parents having children later. I've seen so many parents having children in their teens and 20s (like me) who had babies young and their children are autistic. No surprise that one or both parents in each case is also autistic.

I'm positive it's purely genetics and not age or anything else food or environment related at all.

it's fantastic that more people of all generations are diagnosed now.

I think the NTs are freaking out that they will be the minority while us autistics take over the world!

NOT Sorry us autistics have the right to love to fuck and procreate like the rest of you.

I really agree with this.

It's amazing how you can spot the NT on this thread implying that op has a hidden meaning or agenda for her post.

When that's literally spouted as a "ND bad trait" saying exactly what you mean with no hidden agenda .

How that's the trait that's considered bad is quite beyond me.... but heck I probably miss the point right 😅

SapphireSeptember · 02/07/2024 18:15

Londonwriter · 02/07/2024 17:54

If you don’t have a history of learning disability in your family, you’ll get ‘the children you deserve’. The crazy thing about ‘familial autism’ (as I call it) is that you can have super-amazing kids who seem perfectly ‘normal’ to you, but have ridiculous support needs the minute they leave your care.

Honestly, I have a wonderful, super-smart, very mature, extremely sensible DS7 who needs an EHCP (and a 1-to-1) to be in school. He’s no trouble whatsoever at home and I can take him literally anywhere (or, at least, anywhere I want to go myself with two kids).

Because he has an EHCP, I keep getting adverts from the council telling me I’m eligible for respite care. I always look at it, thinking, “well, I’m so glad they’re able to offer respite care to the parents of children with very high support needs. It must be so tough being a full-time carer for a child with that level of need”…

We don't, other than my sister having a speech impediment when younger (and my niece to a lesser extent.) I wouldn't be surprised if my boyfriend is ND either.
I never had support at school, despite struggling with writing and maths, because I was bright and could read really well. I was also precocious and was comfortable talking to adults. I don't have a super high IQ, but I'm good at remembering things. I also manage alright socially. If little one is like me and his nanny he'll be alright. 😊

RatHole · 02/07/2024 18:13

Londonwriter · 02/07/2024 17:31

Sincerely, it’s what the OP put further up. Autism isn’t a ‘thing’ - it’s a bucket diagnosis from a ticklist of observed behaviours with countless genetic mechanisms.

I’m clearly in my ‘Group 3’. DH and I would be diagnosed autistic if we were children now. We have two autistic kiddos. One has an EHCP and the other is possibly AuDHD. They’re perfectly healthy DS who perfectly take after their parents - as you would expect.

The idea that their autism was ‘caused’ by our age, our diet, pollution, chemicals or trauma, or that we could ‘treat’ the ‘symptoms’ with diet (I adopted a low carb diet due to having gestational diabetes with DS2 and it makes not the blindest bit of difference to my sensory issues) is simply daft TO US.

I can see why this stuff might seem reasonable though if you have no family history of autism and then have a severely learning disabled DS with gut issues and epilepsy. You might be wondering “did I do something to cause this? Why me? How can I treat this disease? Can this be cured? Blah Blah…”

But, to us, it’s obvious what we ‘did’… we, erm, bumped uglies. And our DC’s ‘symptoms’ are, well, their personalities, which their parents reached adulthood also having and often being criticised for.

All due respect, I am autistic as are my children and many of my family.

I didn’t once suggest that what I eat would help everyone. It could help some though.

What I eat helps me, and helps some of my friends to live our lives in a much easier, less stressful way. It didn’t my son, but was worth a trial - he has no limiting issues with food so it didn’t hurt him to try it.

What I object to is the blanket shut down on any suggestions that certain things might ease the difficulties. The assumption that easing symptoms is the same as suggesting a cure.

I don’t believe there is a cure for autism, it is what it is. However in my experience I have come to strongly believe that we can find things that make life more bearable - and why wouldn’t we do that if we could? My daughter has a carefully structured exercise routine that helps her to manage her mental health - that might help some but not others.

The response in many autism community spaces is overwhelmingly negative, which I don’t understand. Surely we all have a responsibility to ourselves to try to live the best lives we can in the varying ways that we can find, without being told that we don’t want autistic people to exist, which is ridiculous as I am autistic! If any autistic people have found ways that have helped them I always love to hear it, because maybe it will work for one of my children, or my friends, or even me. I would never suggest to them that they’re being offensive in any way.

Carock · 02/07/2024 18:12

CatkinToadflax · 02/07/2024 16:51

I’m so pleased to see the reference to prematurity here. My DS1 was born extremely prematurely and is one of the earliest babies of his time to survive (born at 24 weeks nearly 19 years ago). He has multiple complex disabilities and autism is his primary diagnosis.

I have mentioned a few times on MN over the years that, in his case, his autism almost certainly results from his extreme prematurity. What I find baffling is that other posters always want to tell me I’m wrong. On one occasion a particularly charming poster told me I was “talking shit”. How any of the naysayers know more about my child and his circumstances and diagnoses than his entire medical team and his parents, I have no idea.

Yup!

there is more to it than genetics but people are keen to go that way. Prematurity often brings intraventricular haemorrhaging in the brain, amongst similar. The brain needs to find different pathways and then… guess what

hotandpremeni · 02/07/2024 18:11

Amen op.

I think in previous generation if you were rich and ND you would have been considered eccentric, downtown abbeys the grandmother springs to mind or locked away in a posh house never to be seen or recognised by anyone in wider society.

If you were poor you would have probably ended up in mental facility or died.

I personally don't think there more ND around, I think there's more visibility of ND traits due to it not be considered shameful being ND . So society doesn't require as much masking as it is as whole it's more accepting of ND.

Whenever I hear the words eccentric used to describe an older person it now translates to potentially undiagnosed ND from someone who probably has no interest in getting a label.

Peoples needs don't change with a label- the behaviours that have been knocking around for years just understanding and visibility has grown. People now have access to more information that triggers the thought "oh wait I thought that was just me having some weird foibles - that's ND ? But wait there are other people with the same foibles"

And usually it's NT people who point out the behaviours as "not normal" where as the ND person is just existing as they always have. While some NT people are aghast at the thought people might be ok with being ND and worse those ND people aren't showing shame and get their knickers in a twist about it. Bit like NT kids picking on ND for being weird but in adult form.

I say this as a middle aged late diagnosed female with ASD - with my daughter's diagnosis prompting the doctors to go .. you know there's a genetic component right shall we do a few test with you 😵‍💫 low and behold

I can't tell you how much of a head fuck it is for someone to come along and tell you btw you have asd when you have spent a good chunk of your life thinking you just sucked at life. My traits didn't appear with my diagnosis, I just managed/ masked them to fit into society.

Highly functional ND doesn't equal 🟰 life's easier for the person with ND.
It means it's easier for NT people to cope with the ND persons traits and that person to pass as NT

I don't have any problem when I leave my ND house and family. It's usually when I encounter NT people who are hell bent on suggesting ND means the persons defective in some way . Some people tend to think that because the world is geared towards NT so anything that doesn't fit into that "mould" is wrong.

I'm married, house owner, have two children and good circle of friends (all whom un surprising ND) and on a 6 figure salary and have been since I was 30
And I got there by being lucky enough to be surrounded by family teachers who worked with my ND not against it.

I said what I said 🤷‍♀️

magentarain · 02/07/2024 18:09

Londonwriter · 02/07/2024 18:02

No, it isn’t.

The mouse studies are silly. Autism is diagnosed, by definition, from observing social behaviours. Humans are complex social animals. Mice are not. I have read some of the mouse studies - they’re very very silly. Stuff like ‘oh, the mice spend more time burying marbles than other mice, so they’re autistic’. If it was that easy to diagnose autism (in humans), there wouldn’t be a multi-stage multi-hour diagnostic process.

The autistic adults who were institutionalised are not the same autistic adults who are now having children. I’m in my mid-40s and there’s not a snowball’s chance in Hades I’d have been institutionalised. I’m told by my elderly mum that my DS7 would have been caned for bad behaviour and ‘naughtiness’ in her day, not institutionalised.

These are two wholly different groups of people. The only ‘increasing prevalence’ theories that make sense are ones about children surviving brain injury due to extreme prematurity and ‘assortative mating’ between geeks.

Many of my autistic siblings, cousins, aunts and uncles would have been institutionalised, and indeed a few were (before diagnosis was widespread), and later went on to get married.

mrsmiawallace3 · 02/07/2024 18:09

Professor Simon Baron Cohen has produced some amazing research on this topic.

Willyoujustbequiet · 02/07/2024 18:08

FuzzyStripes · 02/07/2024 16:28

To just remind you that autism is genetic?

YABU. Autism can be genetic but it’s not believed to be the only cause.

It’s highly genetic in my family though.

This

There's growing evidence of environmental factors according to some of the world's leading experts.

cremebrulait · 02/07/2024 18:07

what point is OP trying to make?

Last I checked nobody is ENTIRELY sure what causes Autism. And better yet, there is a lot of debate on the DSM-5 diagnostic criteria.

And it is often confused with other coditions.

And it is often diagnosed in some places because an autism diagnosis legally requires certain therapy/interventions/help at school.

So what's your point OP???

EinekleineKatze · 02/07/2024 18:07

behindthemall · 02/07/2024 16:08

Your post says there is more autism, then that there isn’t. Then ages of parents increase prevalence, but it’s wrong to attribute an increase to “mothers reproducing too late in life”.

So I’m not really sure what your point is.

The more is in inverted commas, which leads me to believe that @robotgun is indicating it's not more at all, only that it might seem that way.

ProfessorPeppy · 02/07/2024 18:07

Quantumphysicality · 02/07/2024 17:35

Even then, though, the risk of increased autism is relevant statistically on a population level rather than an on an individual level. it’s really important not to misunderstand this.
it makes beginners difference in individual cases.

As this 2020 roundup states.

“Even so, the absolute chance of having a child with autism is low even for the oldest parents. The researchers in the 2017 study calculated that about 1.5 percent of children born to parents in their 20s will have autism, compared with about 1.58 percent of children born to parents in their 40s.”

www.thetransmitter.org/spectrum/link-parental-age-autism-explained/

I often think about the parental age link. Surely autistic people take longer to mature emotionally, and therefore start relationships later, on the whole? It’s not causation.

raffegiraffe · 02/07/2024 18:04

There's some animal studies which have suggested a higher risk. Changes in neurodevelopment on imaging and pain perception on fluoxetine exposed animal neonates. It makes sense in a way with serotonin being a neuromodulator

Londonwriter · 02/07/2024 18:02

magentarain · 02/07/2024 17:55

It's more complex than this. Autism is caused by a complicated combination of genetic and environmental factors. There are various environemtal factors that have been identified, for example the study on mice showing that the presence of a certain microbiome in the mother during pregnancy reduced the risk of autism-like behaviours in offspring, but we're not at the stage where we can medicate to actually try and control the outcomes.
Also, because autistic people are better integrated now than in the past, when they were often institutionalised, they are more likely to have children, and therefore there are more children being born who are autistic.

No, it isn’t.

The mouse studies are silly. Autism is diagnosed, by definition, from observing social behaviours. Humans are complex social animals. Mice are not. I have read some of the mouse studies - they’re very very silly. Stuff like ‘oh, the mice spend more time burying marbles than other mice, so they’re autistic’. If it was that easy to diagnose autism (in humans), there wouldn’t be a multi-stage multi-hour diagnostic process.

The autistic adults who were institutionalised are not the same autistic adults who are now having children. I’m in my mid-40s and there’s not a snowball’s chance in Hades I’d have been institutionalised. I’m told by my elderly mum that my DS7 would have been caned for bad behaviour and ‘naughtiness’ in her day, not institutionalised.

These are two wholly different groups of people. The only ‘increasing prevalence’ theories that make sense are ones about children surviving brain injury due to extreme prematurity and ‘assortative mating’ between geeks.

Pipsqueaker · 02/07/2024 18:01

Predisposition to Autism is genetic.

Our genes interact with the environment in complex ways.

I think that our modern environment ‘favours’ autistic traits.

raffegiraffe · 02/07/2024 17:58

robotgun · 02/07/2024 16:52

I would v much imagine that a hefty proportion of women who are depressed/anxious to the point of needing to continue SSRIs through pregnancy could have a certain underlying disorder causing their anxiety/depression... called autism...

Yeah I guess that's the issue. So many confounders and never going to be able to conduct a study to show causation. The only things I've read showed association.

ProfessorPeppy · 02/07/2024 17:57

It’s genetic, and epigenetic to an extent.

Since DS1 got his Level 1 Autism/ADHD diagnoses, I’ve spotted it on all sides of my/DH’s families.

I used to think his mum had a personality disorder, but it’s ‘just’ maladaptive autism coping mechanisms 🤣 my mum has chronic ADHD, one of the worst cases I’ve ever encountered 🤣🤣

magentarain · 02/07/2024 17:55

It's more complex than this. Autism is caused by a complicated combination of genetic and environmental factors. There are various environemtal factors that have been identified, for example the study on mice showing that the presence of a certain microbiome in the mother during pregnancy reduced the risk of autism-like behaviours in offspring, but we're not at the stage where we can medicate to actually try and control the outcomes.
Also, because autistic people are better integrated now than in the past, when they were often institutionalised, they are more likely to have children, and therefore there are more children being born who are autistic.

Londonwriter · 02/07/2024 17:54

SapphireSeptember · 02/07/2024 17:34

This being a worry of mine, I'm 35, my boyfriend is 62. Pregnant with my first child and I know autism and ADHD run in my family. Didn't know about the age of the parents link until I was quite far along in my pregnancy, (although both my mum and my sister were much younger than me when they were having kids, me and my siblings and my niece are ND to some extent.) I'm more worried about the severity of it, than whether or not my little boy is going to be autistic.

If you don’t have a history of learning disability in your family, you’ll get ‘the children you deserve’. The crazy thing about ‘familial autism’ (as I call it) is that you can have super-amazing kids who seem perfectly ‘normal’ to you, but have ridiculous support needs the minute they leave your care.

Honestly, I have a wonderful, super-smart, very mature, extremely sensible DS7 who needs an EHCP (and a 1-to-1) to be in school. He’s no trouble whatsoever at home and I can take him literally anywhere (or, at least, anywhere I want to go myself with two kids).

Because he has an EHCP, I keep getting adverts from the council telling me I’m eligible for respite care. I always look at it, thinking, “well, I’m so glad they’re able to offer respite care to the parents of children with very high support needs. It must be so tough being a full-time carer for a child with that level of need”…

Cymbalssymbols · 02/07/2024 17:51

Well said OP. Just wanted to add my opinion to this. I don't think autism is created more often by parents having children later. I've seen so many parents having children in their teens and 20s (like me) who had babies young and their children are autistic. No surprise that one or both parents in each case is also autistic.

I'm positive it's purely genetics and not age or anything else food or environment related at all.

it's fantastic that more people of all generations are diagnosed now.

I think the NTs are freaking out that they will be the minority while us autistics take over the world!

NOT Sorry us autistics have the right to love to fuck and procreate like the rest of you.

Inyournewdress · 02/07/2024 17:49

I fear for DD, she has parents who are both old and both quite probably undiagnosed neurodivergent. Ah well, at least we understand each other 😂😳🤣

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