I too hope that we can find cures for cancer, abolish homophobia and so on but these things don't really get to the problem of pain progress doesn't seem to be able to deal with the depths if human depravity, with natural disasters, with diseases and congenital birth defects caused by random genetic mutation. Progress isn't able to deal with (well, it certainly hasn't so far) the propensity of human beings to kill, maim and torture each other, to stand by while others suffer, to say 'pull up the ladder, Jack, I'm all right.'
Now, your answer suggests that because the 'universe is what it is' all this is just how things are, and that you are basically ok with that. It's easy to feel awe at the mind-blowing vastness of the universe and the richness of life on earth anyone can do that. I do it too. But I don't feel awe and wonder at pain and suffering and these things are as much a part of the universe as grandeur and rich variety are.
So. Either we simply ignore the problem of pain or kid ourselves that human progress can simply eradicate it (an idea that has no evidence to back it up) or we can, quasi-stoically, say that pain is part of the cosmos and that is how it is (which is ok until we, or someone we know, is affected by unendurable suffering). Or we have a response which helps us to have hope and equips us to try and do what we can to mitigate it, and to reach out to those who suffer.
Now, for me, Christian faith does that. As Fizzoclock says, I believe that nothing can separate us from the love of God, and that his love can, and will, ultimately mend everything. That doesn't stop me having to deal with the reality of life -- but it gives me resources for dealing with life's pains and sorrows hopefully. I am commanded to reach out to those in pain and suffering in the light of that hope and love.
The question I was asking was what helps you deal with life's pains and sorrows?